Index|Info|Foro|Docs|Alternativas|Links|Contact|English|Conceptos|Inventario
Alternativas en la web / Alternatives on line
Dado el incremento en importancia de los recursos de internet, se incluyen en la página del GTEMA- Grupo de Trabajo Especializado en Métodos Alternativos 87 enlaces sobre el uso de métodos alternativos y complementarios en investigación, enseñanza y ensayo. / Due to the increasing importance of world-wide web internet resources, 87 links on alternative and complementary methods used for research, education and testing are included.
INDICE / INDEX:
- 1 Bases de Datos sobre Alternativas / Alternative Data Bases
2 Protocolos / Protocols
3 Enseñanza y Formación / Education & Training
4 Simulación en Linea / On-line Simulation
5 Reducción y Refinamiento / Reduction & Refinement
6 Legislación / Legislation
1 Bases de Datos sobre Alternativas / Alternative Data Bases:
- ALTWEB: The Alternatives to Animal Testing Web Site, a very complete web site with news, etc
http://altweb.jhsph.edu - Guía para búsquedas sobre Alternativas (muy útil) / A Guide to Searching for Alternatives to the use of laboratory animals, by Krys Bottrill, FRAME
http://www.frame-uk.demon.co.uk/guide/index.htm - Alternatives databases
http://oslovet.veths.no/databases.html - MEIC- Multicenter Evaluation of in Vitro Cytotoxicity, MEMO and EDIT projects
CTLU http://www.ctlu.se/CTLU_HOME.html
NICA: http://www.cctoxconsulting.a.se/index.htm - Alternatives on Line by D Sladowski
http://embryo.ib.amwaw.edu.pl/~dslado/invitro/Online5a.htm - Searching for Alternatives UF
http://nersp.nerdc.ufl.edu/~iacuc/alternatives.htm - ATCC- American Type Culture Collection
http://www.atcc.org/ - ECACC- European Collection of Cell Cultures
http://www.camr.org.uk - Cell Lines Collections
http://www.biotech.ist.unige.it/cldb/indexes.html - NetVet, the electronic Zoo
http://netvet.wustl.edu/e-zoo.htm - Toxicology in Vitro
http://www.elsevier.nl/cdweb/journals/08872333/viewer.htt - ATLA- Alternatives to Laboratory Animals
http://www.frame-uk.demon.co.uk/atlahome.htm - Reports and Recommendations of the European Centre for Validation of Alternative Methods (ECVAM)
http://altweb.jhsph.edu/science/pubs/ECVAM/ecvam.htm
2 Protocolos / Protocols:
- INVITTOX - FRAME/ERGATT/ECVAM Data base of protocols on in vitro experimental methods
http://www.invittox.com/ - OECD list of protocols for toxicity assessment
http://www.oecd.org/ehs/test/testlist.htm - Model organisms for biomedical research / Modelos experimentales
http://www.nih.gov/science/models/ - Alternatives annotated bibliography
http://sis.nml.nih.gov/altanim.htm - lternatives to Skin Irritation Testing in Animals
http://www.invitroderm.com/ - Corrositex: An In Vitro Method for Assessing Dermal Corrosivity Potential of Chemicals, NIH publication 99-4495 ICCVAM
http://iccvam.niehs.nih.gov/corrode.htm - LLNA -The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds
http://iccvam.niehs.nih.gov/llnarep.htm - FETAX- Frog Embryo Teratogenesis Assay - Xenopus
http://iccvam.niehs.nih.gov/fetax.htm - Flow Cytometry Protocols
http://www.biochem.mpg.de/valet/protoco1.html - Molbio/biotechnology protocols and software sites, Paul N. Hengen
http://www-lmmb.ncifcrf.gov/~pnh/
3 Enseñanza y Formación / Education & Training:
- Norina database: cita más de 3800 audiovisuales / audiovisuals inventory
http://oslovet.veths.no/NORINA/ - AVAR alternatives in education database
http://arrs.envirolink.org/avar/alted_db.htm - World Animal Net web site
http://worldanimal.net/humane-ed.html - EuroNICHE- European network of Individuals and campaigns for Humane Education
http://www.euroniche.internetworking.de/ and http://eniche.ong.ro, the book 'From Guinea Pig to Computer Mouse' Alternatives in Education - new approaches for a new millennium' video. Info., Nick Jukes, EuroNICHE Co-ordinator, lynx@gn.apc.org - Alternatives to the Use of Animals in Higher Education, ECVAM WR 33, ATLA 27: 39-52, 1999
http://altweb.jhsph.edu/science/pubs/ECVAM/ecvam33.htm - ANZCCART- Australian and New Zealand Council for the Care of Animals in Research and Teaching
http://www.adelaide.edu.au/ANZCCART/ - BioEd- Biology Education Resources
http://www-hpcc.astro.washington.edu/scied/biology.html - SciEd- Science and Mathematics Education Resources
http://www-hpcc.astro.washington.edu/scied/science.html - The Whole Mouse Catalog, mice and rats information
http://www.rodentia.com/wmc/ - CLIVE- Computer Aided Learning in Veterinary Education
http://www.clive.ed.ac.uk/ - OSERA- Ohio Scientific Education and Research Association
http://www.osera.org/index.htm - Questions People Ask About Animals in Research; With Answers from The American Physiological Society
http://www.faseb.org/aps/pubaff/animals/index.html - Sniffy the Virtual Rat Software for teaching operant conditioning
http://brookscole/technology/products/sniffy/4.5/mtsnf.html - Curso de Introducción a la Inmunología Porcina
http://www.3tres3.com/welcome.htm - Fondo Documental de la SECAL: videos y CDs sobre el animal de Laboratorio
http://www.secal.es/fondo.htm
4 Simulación en Linea ! / On-line Simulation !:
- The Axon Potential Simulator
http://www.phypc.med.wayne.edu/jeffram/axon3.htm - HyperHeart- bloodflow, aortic/ventricular volumes and pressures in a normal cardiac cycle
http://medstat.med.utah.edu/kw/pharm/index.html - On-Line Pharmacokinetic Simulations
http://www.cop.ufl.edu/safezone/pat/pha5127/SIMULATN.HTM - Virtual Dissections of a Frog: focused to undergraduate students:
Vfrog, http://www-itg.lbl.gov/vfrog/,
Net-Frog, http://teach.virginia.edu/go/frog - Sheep Brain Dissection
http://www.exploratorium.edu/memory/braindissection/ - Cat Diseccion Online
http://www.bhs.berkeley.k12.ca.us/departments/Science/anatomy/cat/ - Anatomically Correct: The On-line Cat Dissection
http://library.thinkquest.org/15401/ - The Virtual Pig Dissection
http://mail.fkchs.sad27.k12.me.us/fkchs/vpig/ - Visible Human: 3-D representation of the human body
http://www.nlm.nih.gov/research/visible/visible_human.html - The Heart: An Online Exploration
http://sln.fi.edu/biosci/heart.html - The Human Brain
http://uta.marymt.edu/~psychol/brain.html - Interactive Brain Atlas: Digital anatomist
http://www9.biostr.washington.edu/cgi-bin/DA/imageform - Brain Atlas: The Whole (and diseases)
http://www.med.harvard.edu/AANLIB/home.html - The Mouse Brain Library, Atlas and iScope (Nissl-stained brain sections, microscope slides)
http://www.nervenet.org/mbl/mbl.html - The Digital Anatomist
http://sig.biostr.washington.edu/projects/da/ - Neuroanatomy Interactive Syllabus
http://www9.biostr.washington.edu/cgiin/DA/PageMaster?atlas:NeuroSyllabus+ffpathIndex:Splash^Page^Syllabus+2 - Interactive Atlas of Thoracic viscera
http://www9.biostr.washington.edu/cgi-in/DA/PageMaster?atlas:Thorax+ffpathIndex:Thorax^Splash+2 - 2D and 3D views of the Knee
http://www9.biostr.washington.edu/cgi-bin/DA/PageMaster?atlas:Knee+ffpathIndex:active1+2 - Cells alive!
http://www.cellsalive.com/ - Selected Microscopy Resources for K-12 Education
http://www.mwrn.com/feature/educatio.htm - Virtual Plant Cell
http://ampere.scale.uiuc.edu/~m-lexa/cell/cell.html - Movies
http://www.bio.davidson.edu/biology/courses/movies.html - Virtual Gastroscopy (Quicktime required), A fly through the esophagus and stomach of the Visible Human
http://www.uke.uni-hamburg.de/institute/imdm/idv/publikationen/mia97/movies/gastro.mov - Muscle Contraction Tutorial (freeware)
http://www.clive.ed.ac.uk/web/queries/catalog/program.idc?PRG_Id=78 - Normal Ear of Dogs and Cats (freeware)
http://www.clive.ed.ac.uk/web/queries/catalog/program.idc?PRG_Id=166
5 Reducción y Refinamiento / Reduction & Refinement:
- Reducing the Use of Laboratory Animals in Biomedical Research: Problems and Possible Solutions : ECVAM Workshop Report 29
http://altweb.jhsph.edu/science/pubs/ECVAM/ecvam29.htm - OECD Draft Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Humane Endpoints for Experimental Animals used in Safety Evaluation"
http://www.oecd.org/ehs/test/DGD.pdf - Canadian Council on Animal Care (CCAC) guidelines on: choosing an appropriate endpoint in experiments using animals for research, teaching and testing
http://www.ccac.ca/english/gdlines/endpts/appopen.htm - Guide for the Care and Use of Laboratory Animals (NAS)
http://stills.nap.edu/readingroom/books/labrats/ - A Bibliography for Members of Institutional Animal Care and use Committees
http://www.animalwelfare.com/Lab_animals/biblio/iacuc2.htm - How to Write an Animal Use Protocol
http://www.uchsc.edu/sm/animal/How_to_write_an_animal_proto.htm - Euthanasia Recommendations
http://www.uchsc.edu/sm/animal/AVMA_Euthanaisa_Recommendations.html - An alternative method for rat fixation when giving subcutaneous, intramuscular and intraperitoneal injections ("Camilla´s method")
http://www.lawte.org/exchange/%5Cmerel%5Ccamilla.html - The importance of non-statistical design in refining animal experiments
http://www.adelaide.edu.au/ANZCCART/publications/fs17.pdf - Readings and resources on The Third R: Refinement
http://www.vetmed.ucdavis.edu/Animal_Alternatives/REFINE.htm - Laboratory Animals online documents: very useful
http://www.lal.org.uk/pdf.htm - Publicaciones de Laboratory Animals en Español (SECAL)
http://www.secal.es/publicac.htm - Animales de Experimentacion. The Spanish-Language Magazine of Laboratory Animal Science
http://www.anidex.com/ - Alternatives to animal testing bibliography with abstracts
http://sis.nlm.nih.gov/altaniml.htm - Compilation of literature on the assessment of animal welfare and animal distress
http://www.vetinfo.demon.nl/aw/index.html - The Transgenic / Targeted Mutation Database
http://tbase.jax.org/ - Transgenic Mouse Facility Home Page
http://darwin.bio.uci.edu/~tjf/index.html - Animal web sites
http://www.uchsc.edu/sm/animal/Animal_Web_Sites.htm
6 Legislación / Legislation:
- European Union Legislation Searcher
In Spanish http://europa.eu.int/eur-lex/es/search.html
In English http://europa.eu.int/eur-lex/en/search.html - European Convention for the Protection of Vertebrate Animals Used for Experimental and other Scientific Purposes
http://www.uku.fi/laitokset/vkek/Sopimus/convention.html - Council Directive 86/609/EEC of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the Protection of Animals Used for Experimental and other Scientific Purposes
http://europa.eu.int/eur-lex/en/lif/dat/1986/en_386L0609.html - European Union Legislation related to Protection of Animals
http://europa.eu.int/eur-lex/en/lif/reg/en_register_1540.html - Animal Protection Legislation Links
http://worldanimal.net/legislinks.html
Fuente / Source: Guillermo Repetto, Ana del Peso, Manuel Salguero, Manuel Repetto (1999)Inventory of the Spanish Institutions and Scientists Involved in Alternatives to the use of Laboratory Animals (Refinement, Reduction or Replacement) Revista de Toxicología 16: 50-127.
Si tienes sugerencias para incluir en las páginas del GTEMA- Grupo de Trabajo Especializado en Métodos Alternativos, por favor indícalo a Guillermo <repetto@us.es> / If you have suggestions of web sites to include, please let us know at the address repetto@us.es.
