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The Evolutionary Genetics section of the Instituto Cavanilles de Biodiversitat i Biologia Evolutiva (University of Valencia, Spain) is devoted to the theoretical, computational, comparative, and experimental study of evolution within the fields of genetics, genomics, microbiology, molecular biology, and population biology. At present, it includes four full professors, four associate professors, four postdocs, and ten PhD students.

Several of its members are also associated to the Join Unit of Genomics and Health, which integrates the University of Valencia and the Centro Superior de Investigaci�n en Salud P�blica (CSISP).

Selected recent research

Evolution of animal symbiosis

Symbiosis is a strong factor promoting evolutionary novelty. Its study requires a joint analysis of both the eukaryotic host and its intimately associated microorganisms. To achieve this goal, we use genomic and metagenomic approaches.

Synthetic biology

The tree of life shows a variety of microorganisms with minimal genomes whose study can provide clues for the understanding and enginneering of minimal cells with applications in biomedicine, bioremediation, and biotechnology.

Genetic studies of aphids: Taxonomy and reproductive polyphenism

We are interested in identifying the genes and routes governing the mode of reproduction in aphids (parthenogenesis vs. sexuality).

Molecular epidemiology of infectious diseases

We use modern sequencing, population genetics, and molecular systematics to investigate disease outbreaks and elucidate evolutionary patterns in viruses and other pathogenic organisms.

Genetics and experimental evolution of viruses

Molecular and experimental evolution are combined to seek a better understanding of the origin and maitenance of viral genetic variation, paying special attention to basic mechanisms such as mutation and selection.

Selected recent publications
  • L�pez-Madrigal, S., Latorre, A., Porcar, M., Moya, A., Gil, R. 2013. Mealybugs nested endosymbiosis: going into the 'matryoshka' system in Planococcus citri in depth. BMC Microbiology 13:74. [PDF]
  • Pati�o-Navarrete, R., Moya, A., Latorre, A., Peret�, J. 2013. Comparative genomics of Blattabacterium cuenoti: the frozen legacy of an ancient endosymbiont genome. Genome Biol Evol. 5(2):351-61. [PDF]
  • Belda, E., Silva, F.J., Peret�, J., Moya, A. 2012. Metabolic networks of Sodalis glossinidius: a systems biology approach to reductive evolution. PLoS One. 7(1):e30652. [PDF]
  • Cuevas, J.M., Domingo-Calap, P., Sanju�n, R. 2012. The fitness effects of synonymous mutations in DNA and RNA viruses. Mol. Biol. Evol. 29: 17-20. [PDF]
  • Gonz�lez-Domenech, C.M., Belda, E., Pati�o-Navarrete, R., Moya, A., Peret�, J., Latorre, A. 2012. Metabolic stasis in an ancient symbiosis: genome-scale metabolic networks from two Blattabacterium cuenoti strains, primary endosymbionts of cockroaches. Bmc Microbiology. 12(Suppl 1):S5. [PDF]
  • Gosalbes, M.J., Abellan, J.J., Durb�n, A., Pe�rez-Cobas, A.E., Latorre, A., Moya, A. 2012. Metagenomics of human microbiome: beyond 16s rDNA. Clin Microbiol Infect. 18 (Suppl. 4): 47-49. [PDF]
  • Lira, F., Hern�ndez, A., Belda, E., S�nchez, M.B., Moya, A., Silva, F.J., Mart�nez, J.L. 2012. Whole-Genome Sequence of Stenotrophomonas maltophilia D457, a Clinical Isolate and a Model Strain. Journal of Bacteriology. 194(13):3563. [PDF]