Selected recent research |
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Evolution of animal symbiosis Symbiosis is a strong factor promoting evolutionary novelty. Its study requires a joint analysis of both the eukaryotic host and its intimately associated microorganisms. To achieve this goal, we use genomic and metagenomic approaches. |
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Synthetic biology The tree of life shows a variety of microorganisms with minimal genomes whose study can provide clues for the understanding and enginneering of minimal cells with applications in biomedicine, bioremediation, and biotechnology. |
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Genetic studies of aphids: Taxonomy and reproductive polyphenism We are interested in identifying the genes and routes governing the mode of reproduction in aphids (parthenogenesis vs. sexuality). |
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Molecular epidemiology of infectious diseases We use modern sequencing, population genetics, and molecular systematics to investigate disease outbreaks and elucidate evolutionary patterns in viruses and other pathogenic organisms. |
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Genetics and experimental evolution of viruses Molecular and experimental evolution are combined to seek a better understanding of the origin and maitenance of viral genetic variation, paying special attention to basic mechanisms such as mutation and selection. |
Selected recent publications |
- L�pez-Madrigal, S., Latorre, A., Porcar, M., Moya, A., Gil, R. 2013. Mealybugs nested endosymbiosis: going into the 'matryoshka' system in Planococcus citri in depth. BMC Microbiology 13:74. [PDF]
- Pati�o-Navarrete, R., Moya, A., Latorre, A., Peret�, J. 2013. Comparative genomics of Blattabacterium cuenoti: the frozen legacy of an ancient endosymbiont genome. Genome Biol Evol. 5(2):351-61. [PDF]
- Belda, E., Silva, F.J., Peret�, J., Moya, A. 2012. Metabolic networks of Sodalis glossinidius: a systems biology approach to reductive evolution. PLoS One. 7(1):e30652. [PDF]
- Cuevas, J.M., Domingo-Calap, P., Sanju�n, R. 2012. The fitness effects of synonymous mutations in DNA and RNA viruses. Mol. Biol. Evol. 29: 17-20. [PDF]
- Gonz�lez-Domenech, C.M., Belda, E., Pati�o-Navarrete, R., Moya, A., Peret�, J., Latorre, A. 2012. Metabolic stasis in an ancient symbiosis: genome-scale metabolic networks from two Blattabacterium cuenoti strains, primary endosymbionts of cockroaches. Bmc Microbiology. 12(Suppl 1):S5. [PDF]
- Gosalbes, M.J., Abellan, J.J., Durb�n, A., Pe�rez-Cobas, A.E., Latorre, A., Moya, A. 2012. Metagenomics of human microbiome: beyond 16s rDNA. Clin Microbiol Infect. 18 (Suppl. 4): 47-49. [PDF]
- Lira, F., Hern�ndez, A., Belda, E., S�nchez, M.B., Moya, A., Silva, F.J., Mart�nez, J.L. 2012. Whole-Genome Sequence of Stenotrophomonas maltophilia D457, a Clinical Isolate and a Model Strain. Journal of Bacteriology. 194(13):3563. [PDF]