Viral mutation rates
This on-line resource contains
estimates of the spontaneous mutation rate for 25 different viruses.
Several independent estimates are
available for some viruses.
Viral mutation rates can be
expressed as substitutions per nucleotide site per cell infection
(s/n/c) or as substitutions per nucleotide per strand copying
(s/n/r).
Mutation rates per cell
infection
Mutation rates per strand
copying
The goal of this site is to
provide an easily accessible dataset and to promote the use of
common units. References to original publications and
methodological details of each estimate are provided.
Data are taken from the following
article, which also contains a detailed description of the methods
used:
Sanjuán R., Nebot M.R., Chirico
N., Mansky L.M., Belshaw R. (2010). Viral mutation rates.
J. Virol.
84: 9733-9748. [pdf]
Two recent estimates which do not
appear in the above paper have been added (foamy virus and HIV-1)
This dataset will be
updated yearly. The goal is to make it as extensive as possible.
Please contact me if you know of any estimate which has not been
included.
Rafael Sanjuán,
Institute Cavanilles for Biodiversity and Evolutionary Biology
University of Valencia, Spain
Tel: +34 963 543 270
E-mail: rafael.sanjuan@uv.es
Mailing address: Institut Cavanilles de Biodiversitat i Biologia
Evolutiva
Parc Cientific de la Universitat de Valencia
C/ Catedratico Agustin Escardino n° 9
46980 Paterna, Valencia
Spain
