Biomedical applications of bacteriophages, including diagnosis, prevention, and therapy, as an alternative tool against multidrug-resistant bacteria. Isolation and characterization of novel phages, directed evolution for phage optimization, resistant emergence, and nanotechnology.
Isolation and characterisation of extracellular vesicles (EVs) in different helminth parasites. Identification of molecules present in EVs. Analysis for the usefulness of EVs in helminthiasis control and other diseases (diagnosis, vaccination and treatment).
Epidemiological (life cycle, transmission, population dynamic) and ecological (influence of biotic and abiotic factors) analysis of human and animal parasites (especially rodents). Analysis of behaviour and response of parasites after natural disasters.
Study of the evolution of complete genomes and the genes present in them, with special emphasis on bacteria and viruses.
The main research lines are: i) Evolution of symbiosis ii) Synthetic biology iii) Genetic study of aphids
We use viruses as model organisms in the laboratory to study evolutionary processes on an experimental basis.
Epidemiological study of food-transmitted human parasites (protozoa and helminths). Study of the influence of intrinsic and extrinsic factor on parasitism. Morphological and molecular diagnosis and identification of parasite species. Anisakiasis study.
Creation of Geographic Information Systems with the use of satellite images and thematic maps (climate, surface, parasitological parameters, etc.) for the modelling of epidemiology and the transmission of human / animal parasites, as well as the influence of climate change on them.
Diagnosis and epidemiological study of human ectoparasite arthropods (mosquitoes, myiasis, lice, bedbugs, etc.). Pest control and vectors on an individual level. Analysis of vector-transmitted parasitic diseases and influence of climate change on them.
This line of research focuses on the study of the epidemiology of rotavirus and norovirus through the application of molecular techniques (RT-PCR, qPCR, cDNA sequencing, etc.) and the detection of new variants of viral genotypes.
Use of genetic and genomic information of pathogenic microorganisms (bacteria and viruses) to study their spread in human populations and in their natural reservoirs, complementing the tasks of epidemiological care and control.
There's an analysis for the parasites-food intolerance relationship and the prevalence, transmission routes and risk factors of suffering from intestinal parasitosis, the correlation between parasitosis and the reception of breastfeeding, as well as the parasites-child development relationship.
The aim of this line of research is to study the pathogenic mechanisms and the immune response of infections by the two main enteric viruses (rotavirus and norovirus).
The aim of this line of research is to study the interactions that occur between enteric viruses and the host without excluding the interactions that occur between enteric viruses and the intestinal microbiota or the interaction between the intestinal microbiota and the host.
Study of molecular interactions between helminth parasites and their hosts. Tools destined to the control of said parasitosis (proteins and recombinant peptides along with polyclonal antibodies) stem from identified molecules.
Epidemiological study of teniasis / cisticercosis, with special reference to the third new parasitic tapeworm: Taenia asiatica. Ultrastructural studies of infective forms. Secretomics analysis of cisticercosis' infective forms (eggs) of the three human Taenia species.
Monitoring natural and anthropogenic environments for disease surveillance, specially viral outbreaks. Detection of emerging viruses in natural environments and development of quantification techniques for population monitoring. Study of new transmission routes of emerging viruses.
Using various experimental approaches, we aim to identify and characterise mechanisms in the generation of RNA virus diversity, and to obtain quantitative estimates of mutation rates in RNA viruses.
