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Evolutionary Systems Biology

Study of the evolution of complete genomes and the genes present in them, with special emphasis on bacteria and viruses.

Experimental evolution of viruses

We use viruses as model organisms in the laboratory to study evolutionary processes on an experimental basis.

Molecular epidemiology of rotavirus and norovirus infections

This line of research focuses on the study of the epidemiology of rotavirus and norovirus through the application of molecular techniques (RT-PCR, qPCR, cDNA sequencing, etc.) and the detection of new variants of viral genotypes.

Molecular epidemiology

Use of genetic and genomic information of pathogenic microorganisms (bacteria and viruses) to study their spread in human populations and in their natural reservoirs, complementing the tasks of epidemiological care and control.

Pathogenesis and immune response of enteric virus infections: rotavirus and norovirus

The aim of this line of research is to study the pathogenic mechanisms and the immune response of infections by the two main enteric viruses (rotavirus and norovirus).

Study of virus / microbiota / host interactions

The aim of this line of research is to study the interactions that occur between enteric viruses and the host without excluding the interactions that occur between enteric viruses and the intestinal microbiota or the interaction between the intestinal microbiota and the host.

Viral mutation and evolution

Using various experimental approaches, we aim to identify and characterise mechanisms in the generation of RNA virus diversity, and to obtain quantitative estimates of mutation rates in RNA viruses.