Position

Full Professor of Genetics, Department of Genetics
University of Valencia (Spain)

Institut Cavanilles de Biodiversitat i Biologia Evolutiva (ICBiBE), University of Valencia.

CIBER en Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III

Centro Superior de Investigación en Salud Pública (CSISP), Generalitat Valenciana.

EDUCATION RESEARCH PEOPLE PUBLICATIONS TEACHING CONTACT

You can also follow my work in Academia.edu

My new book in both Spanish ("La evolución, de Darwin al genoma") and Catalan ("L'evolució, de Darwin al genoma") versions has just been published.

I have coauthored a book on GMOs ("Transgénicos") with Carmen Fenoll, from UCLM.

Education

1982      B.Sc. (Biology), University of Valencia

1987      Ph.D. (Genetics), University of Valencia

Major research interests

My main research interests are in population and evolutionary genetics, molecular and evolutionary epidemiology, molecular systematics and genomics, bioinformatics and conservation biology. I am currently working on the molecular evolutionary epidemiology of different pathogens, mainly RNA viruses, such as hepatitis C virus (HCV) and human immunodeficiency virus (HIV), and bacteria, such as Legionella pneumophila. Our basic approach is the analysis of nucleotide sequence variability at different levels, from intrapatient to world-wide samples, depending on the speficic goals of the different projects.

Previously I have been studied the population and evolutionary biology of Mediterranean endemic Limonium (Plumbaginaceae) species, by using an array of genetic markers (RAPDs, AFLPs, microsatellites, isozymes) and including the analysis of quantitative traits. Besides, I have been very involved in the establishment of the Bioinformatics Service at my university, of which I have been in charge from 1994 to 2000. I have also helped in the development of the Automated Sequencing Service. I have served as head of the Bioinformatics Service at the University of Valencia from 1994 until 2001 and as Scientific Expert on the Spanish National Biosafety Council since 1998.

Current research projects

• Molecular and evolutionary epidemiology of RNA virus
• Molecular populations genetics and evolutionary epidemiology of Legionella pneumophila
• Comparative and evolutionary genomics, phylogenomics
• Population and evolutionary genetics of pathogens, parasites and their vectors
• Conservation genetics of endangered plant species

People

Research Associates

Dr. Juan José Abellán, CIBERESP, CSISP

Dr. María Alma Bracho Lapiedra, CIBERESP, CSISP

Dr. Mireia Coscollá, CIBERESP, CSISP

Dr. Xavier López-Labrador, CIBERESP, CSISP

Postdocs

Dr. Ferrán Palero

Graduate students

Alicia Amadoz, (PhD thesis: Bioinformatic methods for molecular epidemiology analysis)

Vicente Sentandreu, (PhD thesis: Evolutionary dynamics of HCV and HIV in coinfected patients)

Former PhD students

Dr. Mireia Coscollá, (PhD thesis: Population genetics and molecular epidemiology of Legionella pneumophila)

Dr. Iñaki Comas, MRC-Division of Mycobacterial Research (PhD thesis: Phylogenomics of Proteobacteria, 2008)

Dr. Marisa Palop Esteban, (PhD thesis: Population genetics with SSR markers of endangered Limonium sp, 2003.)

Dr. Manuela Torres-Puente, (PhD thesis: Molecular epidemiology of HCV in the Comunidad Valenciana, 2004)

Dr. Carmen Palacios, (PhD thesis: Conservation genetics and evolution of Limonium spp, 1997)

Dr. Adoración Hernández, (PhD thesis: Effects of recurrent bottlenecks in experimental populations of Drosophila psuedobbscura, 1993)

Former Postdocs

Dr. Borys Wróbel, Institut of Oceanography - Polish Academy of Sciences, Methods for dating viral infections.

Undergraduate students

Juan Angel Patiño Galindo

Marta Adriana Pinto Carbó

Collaborations

Dr. Andrés Moya, ICBiBE, CIBERESP, CSISP

Dr. José Manuel Cuevas, ICBiBE, CIBERESP

Dr. Rafael Sanjuán, ICBiBE

Dr. Juan Carlos Galán, CIBERESP, Hosp. Ramón y Cajal

Dr. África Holguín, CIBERESP, Hosp. Ramón y Cajal

Dr. Vicente Ausina, CIBERES, Hosp. Germans Trias i Pujol

Dr. Elisa Martró, CIBERESP, Hosp. Germans Trias i Pujol

Dr. Miguel Thomson, Instituto de Salud Carlos III

Dr. Manuel Zúñiga, IATA

Dr. Carmen Amaro, Dpto. Microbiología, Univ. Valencia

Dr. Pilar Catalán, Univ. Zaragoza

Dr. José Gabriel Segarra, Univ. Zaragoza

Dr. María Dolores Bargues, Dpt. Parasitología, Univ. Valencia

Selected publications PubMed

González-Candelas, F. 2010. Molecular Phylogenetic Analyses in Court Trials. In: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0021575 [PDF]

González-Candelas, F.; López-Labrador, F.X. 2010. Clinical relevance of genetic heterogeneity in HCV. Future Virology 5(1): 33-49 [PDF]

Novais, Â.; Comas, I.; Baquero, F.; Cantón, R.; Coque, T.M.; Moya, A.; González-Candelas, F.; Galán, J.C. 2010. Evolutionary Trajectories of Beta-Lactamase CTX-M-1 Cluster Enzymes: Predicting Antibiotic Resistance. PLoS Pathogens 6(1): e1000735. doi:10.1371/journal.ppat.1000735. [Full text] [PDF] [Supplementary Material]

Sánchez, B.; Zúñiga, M.; González-Candelas, F.; González de los Reyes-Gavilán,C.; Margolles,A.. 2010. Bacterial and eukaryotic phosphoketolases: phylogeny, distribution and evolution. Journal of Molecular Microbiology and Biotechnology 18: 37-51. [Abstract] [PDF]

Coscollá, M.; González-Candelas, F. 2009. Comparison of clinical and environmental samples of Legionella pneumophila at the nucleotide sequence level. Infection, Genetics and Evolution 9: 882-888. [Abstract] [PDF] [Supplementary Data]

Coscollá, M.; González-Candelas, F. 2009. Direct sequencing of Legionella pneumophila from respiratory samples for Sequence-Based Typing analysis. Journal of Clinical Microbiology 47(9): 2901-2905. [Abstract] [PDF] [Supplemental Data]

Cuevas, J.M.; González, M.;Torres-Puente, M.; Jiménez-Hernández, N.; Bracho, M.A.; García-Robles, I.; González-Candelas, F.; Moya, A. 2009.The role of positive selection in hepatitis C virus. Infection, Genetics and Evolution 9: 882-888. [Abstract] [PDF]

Cuevas,J.M.; Gonzalez-Candelas,F.; Moya,A.; Sanjuan,R. 2009. The effect of ribavirin on the mutation rate and spectrum of Hepatitis C virus in vivo. J. Virol. 83: 5760-5764. [Abstract] [PDF] [Supplemental material]

Cuevas, J.M.; Torres-Puente, M.; Jiménez-Hernández, N.; Bracho, M.A.; García-Robles, I.; Carnicer, F.; Olmo, J.D.; Ortega, E.; González-Candelas, F.; Moya, A. 2009. Combined therapy of interferon plus ribavirin promotes multiple adaptive solutions in hepatitis C virus. Journal of Medical Virology 81(4): 650-656. [Abstract] [PDF]

Domingo-Calap, P.; Sentandreu,V.; Bracho, M.A.; González-Candelas, F.; Moya,A.; Sanjuán, R. 2009. Unequal distribution of RT-PCR artifacts along the E1-E2 region of Hepatitis C virus. Journal of Virological Methods 161: 136-140. [PDF]

Lourenço Jr., V.; Moya, A.; González-Candelas, F.; Carbone, I.; Maffia, L.A.; Mizubuti, E. 2009. Molecular diversity and evolutionary processes of Alternaria solani in Brazil inferred using genealogical and coalescent approaches. Phytopathology 99: 765-774.

Juárez, P.; Comas, I.; González-Candelas, F.; Calvete, J.J. 2008. Evolution of snake venom disintegrins by positive Darwinian selection. Molecular Biology and Evolution 25: 2391-2407; doi:10.1093/molbev/msn179. [Abstract] [PDF] [Full Text]

Bargues, M.D.; Klisiowicz, D.R.; González-Candelas, F.; Ramsey, J.M.; Monroy, C.; Ponce, C-; Salazar-Schettino, P.M.; Panzera, F.; Abad-Franch, F.; Sousa, O.E.; Schofield, C.J.; Dujardin, J.P.; Guhl, F.; Mas-Coma, S. 2008. Phylogeography and genetic variation of Triatoma dimidiata, the main Chagas disease vector in Central America, and its position within the genus Triatoma. PLoS Neglected Tropical Diseases 2(5): e233. doi:10.1371/journal.pntd.0000233.
[Full Text] [PDF] [Suppl. Material]

Bracho, M.A.; Saludes, V.; Martro, E.; Bargallo, A.; González-Candelas, F.; Ausina, V. 2008. Complete genome of a European hepatitis C virus subtype 1g isolate: phylogenetic and genetic analyses. Virology Journal 5: 72.
[Abstract] [Provisional PDF]

Comas, I.; González-Candelas, F.; Zúñiga, M. 2008. Unravelling the evolutionary history of the phosphoryl-transfer chain of the phosphoenolpyruvate:phosphotransferase system by phylogenetic analyses and genome context. BMC Evolutionary Biology 8:147.
[Abstract] [PDF]

Cuevas, J. M.; Torres-Puente, M.; Jiménez-Hernández, N.; Bracho, M. A.; García-Robles, I.; Carnicer, F.; Olmo, J. D.; Ortega, E.; Moya, A.; González-Candelas, F. 2008. Refined analysis of genetic variability parameters in hepatitis C virus and the ability to predict antiviral treatment response. Journal of Viral Hepatitis. Online Early, May 12, 2008. doi:10.1111/j.1365-2893.2008.00991.x.
[Abstract] [Full Text] [PDF] [Suppl.Material]

Cuevas, J.M.; Torres-Puente, M.; Jiménez-Hernández, N.; Bracho, M.A.; García-Robles, I.; Wrobel, B.; Carnicer,F.; del Olmo, F.; Ortega,E.; Moya,A.; González-Candelas,F. (2008) Genetic variability of Hepatitis C Virus before and after combined therapy of interferon plus ri bavirin. PLoSONE 3(8): e3058. doi:10.1371/journal.pone.0003058. [Full Text] [PDF]

Sentandreu, V.; Jiménez-Hernández, N; Torres-Puente, M.; Bracho, M.A.; Valero, A.; Gosalbes, M.J.; Ortega, E.; Moya, A.; González-Candelas, F. (2008) Evidence of Recombination in Intrapatient Populations of Hepatitis C Virus. PLoS ONE 3(9): e3239. doi:10.1371/journal.pone.0003239. [Full Text] [PDF] [Supporting Information]

Torres-Puente, M.; Cuevas, J.N.; Jiménez-Hernández, N.; Bracho, M.A.; García-Robles, I.; Wróbel, B.;Carnicer, F.; del Olmo, F.; Ortega, E.; Moya, A.; González-Candelas, F. 2008. Using evolutionary tools to refine the new hypervariable region 3 within the envelope 2 protein of hepatitis C virus. Infection, Genetics and Evolution 8(1): 74-82. [PDF]

Torres-Puente, M.; Cuevas, J.N.; Jiménez-Hernández, N.; Bracho, M.A.; García-Robles, I.; Wrobel, B.; Carnicer, F.; del Olmo, F.; Ortega, E.; Moya, A.; González-Candelas, F. 2008. Genetic variability in hepatitis C virus and its role in antiviral treatment response. The Journal of Viral Hepatitis 15: 188-199. [Abstract] [PDF] [Suppl.Material]

Torres-Puente, M.; Cuevas, J.N.; Jiménez-Hernández, N.; Bracho, M.A.; García-Robles, I.; Carnicer, F.; del Olmo, F.; Ortega, E.; Moya, A.; González-Candelas, F. 2007. Hepatitis C virus and the controversial role of the interferon sensitivity determining region in the response to interferon treatment. The Journal of Medical Virology 80(2): 247-253. [Abstract] [PDF]

Jimenez-Hernandez N, Sentandreu V, Castro JA, Torres-Puente M, Bracho A, Garcia-Robles I, Ortega E, Del Olmo J, Carnicer F, Gonzalez-Candelas F, Moya A. 2008. Effect of antiviral treatment and host susceptibility on positive selection in hepatitis C virus (HCV). Virus Res. 2008 131(2): 224-232. [Abstract] [PDF]

Palop-Esteban, M.; Segarra-Moragues, J.G.; González-Candelas, F. 2007. Historical and biological determinants of genetic diversity in the highly endemic triploid sea lavender Limonium dufourii (Plumbaginaceae). Molecular Ecology 16(18):3814-27. [PDF]

Torres-Puente, M.; Cuevas, J.M.; Jiménez-Hernéndez, N.; Bracho, M.A.; García-Robles, I.; Carnicer, F.; del Olmo, J.;Ortega, E.; Moya, A.; González-Candelas, F. 2007. Contribution of insertions and deletions to the variability of hepatitis C virus populations. Journal of General Virology 88(8):2198-2203. [PDF]

Amadoz, A.; González-Candelas, F. 2007. epiPATH: an information system for the storage and management of molecular epidemiology data from infectious pathogens. BMC Infectious Diseases 7: 32. [PDF]

Comas, I.; Moya, A.; González-Candelas, F. 2007. From phylogenetics to phylogenomics: the evolutionary relationships of insect endosymbiotic gamma-Proteobacteria as a test case. Systematic Biology 56(1): 1-16. [PDF]

Comas, I.; Moya, A.; González-Candelas, F. 2007. Phylogenetic signal and functional categories in Proteobacteria genomes. BMC Evolutionary Biology 7 (Suppl. 1): S7 (8 February 2007) [PDF]

Garcia-Martinez, J.; González-Candelas, F.; Perez-Ortin, J. 2007. Common gene expression strategies revealed by genome-wide analysis in yeast. Genome Biology 8:R222. [Abstract] [PDF] [PubMed]

Coscollá, M.; González-Candelas, F. 2007. Population structure and recombination in environmental isolates of Legionella pneumophila. Environmental Microbiology 9(3): 643-656. [PDF]

Segarra-Moragues J.G.; Palop-Esteban M.; González-Candelas F.; Catalán P. 2007. Nunatak survival vs. tabula rasa in the Central Pyrenees: a study on the endemic plant species Borderea pyrenaica (Dioscoreaceae). Journal of Biogeography 34: 1893-1906. [Abstract] [PDF]

Jiménez-Hernández, N.; Torres-Puente, M.; Bracho, M. A.; García-Robles, I.; Ortega, E.; del Olmo, J.;Carnicer, F. González-Candelas, F.; Moya, A. 2007. Epidemic dynamics of two coexisting hepatitis C virus subtypes. Journal of General Virology 88(1): 123-133.[Abstract] [PDF]

Comas, I.; Moya, A.; Azad, R.K.; Lawrence, J.G.; González-Candelas, F. 2006. The Evolutionary Origin of Xanthomonadales Genomes and the Nature of the Horizontal Gene Transfer Process. Molecular Biology and Evolution 23(11): 2049-2057. PDF

Coscollá, M.; Gosalbes, M.J.; Catalán, V.; González-Candelas, F. 2006. Genetic variability in environmental isolates of Legionella pneumophila from Comunidad Valenciana (Spain). Environmental Microbiology 8 (6): 1056-1063. PDF

Wróbel, B.; Torres-Puente, M.; Jiménez, N.; Bracho, M.A.; García-Robles, I.; Moya, A.; González-Candelas, F. 2006. Analysis of the overdispersed clock in the short term evolution of hepatitis C virus: using the E1/E2 gene sequences to infer infection dates in a single source outbreak. Molecular Biology and Evolution 23(6):1242-1253. PDF

Czarna, A.; Sanjuán, R.; González-Candelas, F.; Wróbel, B. 2006.Topology testing of phylogenies using least squares methods. BMC Evolutionary Biology 6:105. PDF

Bargues, M.D.; Klisiowicz, D.R.; Panzera, F.; Noireau, F.; Marcilla, A.; Perez, R.; Rojas, M.G.; O’Connor, J.E.; González-Candelas, F.; Galvão, C.; Jurberg, J.; Carcavallo, R.U.; Dujardin, J.P.; Mas-Coma, S. 2006. Origin and phylogeography of the Chagas disease main vector Triatoma infestans based on nuclear rDNA sequences and genome size. Infection, Genetics and Evolution 6(1): 46-62. PDF

López-Labrador, F.-X.; Bracho, M.A.; Berenguer, M.; Coscolla, M.; Rayón, J.M.; Prieto, M.; Carrasco, D.; Gómez, M. D.; Moya, A.; González-Candelas, F. 2006. Genetic similarity of hepatitis C virus and fibrosis progression in chronic and recurrent infection after liver transplantation. Journal of Viral Hepatitis 13: 104-115. PDF

Bracho, M.A.; Carrillo-Cruz, F.Y.; Ortega, E.; Moya, A.; González-Candelas, F. 2006. A new subtype of hepatitis C virus genotype 1: complete genome and phylogenetic relationships of an Equatorial Guinea isolate. Journal of General Virology 87 (6): 1697-1702. PDF

Maria Alma Bracho, María José Gosalbes, Francisco González, Andrés Moya and Fernando González-Candelas. 2006. Molecular epidemiology and evolution in a fulminant hepatitis B virus outbreak. Journal of Clinical Microbiology 44(4): 1288-1294. PDF

Pilar Catalán, José Gabriel Segarra-Moragues, Marisa Palop-Esteban, Carlos Moreno and Fernando González-Candelas. 2006. A Bayesian approach for discriminating among alternative inheritance hypotheses in plant polyploids: the allotetraploid origin of genus Borderea (Dioscoreaceae). Genetics 172(3): 1939-1953. PDF

González-Candelas, F.; Moya, A. 2005. Time and rate of evolution are the key to establish transmission cases. AIDS 19(14): 1552-1553. PDF

Zúñiga, M.; Comas,I.; Linaje, R.; Monedero, V.; Yebra, M. J.; Esteban, C.D.; Deutscher, J.;Pérez-Martínez, G.; González-Candelas, F. 2005. Horizontal Gene Transfer in the Molecular Evolution of Mannose PTS Transporters. Molecular Biology and Evolution 22(8):1673-1685. doi:10.1093/molbev/msi156
[Abstract] [Full Text] [PDF]

Bracho,M. A.; Gosalbes, M. J.; Blasco, D.; Moya, A.; González-Candelas, F. 2005. Molecular Epidemiology of a Hepatitis C Virus Outbreak in a Hemodialysis Unit. J. Clin. Microbiol. 43: 2750-2755.
[Abstract] [Full Text] [PDF]

Comas, I.; Moya, A.; González-Candelas, F. 2005. Validating viral quasispecies with digital organisms: a re-examination of the critical mutation rate. BMC Evolutionary Biology 5: 5.
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Segarra-Moragues, J.G.; Palop-Esteban, M.; González-Candelas; F. and Catalán, P.; 2005. On the verge of extinction: Genetics of the critically endangered Iberian plant species Borderea chouardii (Dioscoreaceae) and implications for conservation management. Molecular Ecology 14: 969-982.
[Abstract] [PDF] [Supplementary Material]

Bracho, M. A.; García-Robles, I.; Jiménez, N.; Torres-Puente, M.; Moya, A., and González-Candelas. F. 2004. Effect of oligonucleotide primers in determining viral variability within hosts. Virology Journal, 1:13.
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Segarra-Moragues, J.G., M. Palop-Esteban, F. González-Candelas & P. Catalán. 2004. Characterization of seven (CTT)n microsatellite loci in the Pyrenean endemic Borderea pyrenaica (Dioscoreaceae). Remarks on ploidy level and hybrid origin assessed through allozymes and microsatellite analyses. Journal of Heredity 95(2):177–183.
[PubMed] [PDF]

Moya, A., E.C. Holmes & F.González-Candelas. 2004. Population genetics and the evolutionary epidemiology of RNA viruses. Nature Reviews in Microbiology 2: 279-288.
[PubMed][PDF]

López-Labrador,F.X., X.-S. He, M. Berenguer, R.C. Cheung, F. González-Candelas, T.L. Wright y H.B. Greenberg. 2004. Genetic variability of hepatitis C virus non-structural protein 3 and virus-specific CD8+ response in patients with chronic hepatitis C. Journal of Medical Virology 72(4): 575-585.
[PubMed] [PDF]

Gil, R. , F. J. Silva, E. Zientz, F. Delmotte, F. González-Candelas, A. Latorre, C. Rausell, J. Kamerbeek, J. Gadau, B. Hölldobler, R. C. H. J. van Ham, R. Gross & A. Moya. 2003. The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes. Proceedings of the National Academy of Sciences USA 100(16): 9388-9393.
[PubMed] [PDF]

Segarra-Moragues, J.G., M. Palop-Esteban, F. González-Candelas & P. Catalán. 2003. Characterization of ten microsatellite loci in the critically endangered Pyrenean yam Borderea chouardii (Dioscoraceae). Molecular Ecology Notes 3(2): 265-267.
[PDF]

Torres-Puente, M., M.A. Bracho , N. Jimenez , I. Garcia-Robles , A. Moya & F. Gonzalez-Candelas. 2003. Sampling and repeatability in the evaluation of hepatitis C virus genetic variability. Journal of General Virology 84(9):2343-50.
[PubMed] [PDF]

González-Candelas, F., M.A. Bracho & A. Moya. 2003. Molecular epidemiology and forensic genetics: application to a hepatitis C virus transmission event in a hemodialysis unit. Journal of Infectious Diseases 187(3): 352-358.
[PubMed] [PDF]

Rodríguez, S., M. Palop, C. Palacios & F. González-Candelas. 2003. Molecular and morphological differentiation in Limonium dufourii (Plumbaginaceae), an endangered Mediterranean plant. Conservation Genetics 4(3): 383-391.
[PDF]

Zúñiga, M., G. Pérez & F. González-Candelas. 2002. Evolution of arginine deiminase (ADI) pathway genes. Molecular Phylogenetics and Evolution 25(3): 429-444.
[PubMed] [PDF]

Marín, I., M.A. Farés, F. González Candelas, E. Barrio & A. Moya. 2001. Detecting changes in the functional constraints of paralogous genes. Journal of Molecular Evolution 52(1): 17-28.
[PubMed] [PDF]

Palop, M., Palacios, C. & F. González Candelas. 2000. Development and across species transferability of microsatellite markers in the genus Limonium (Plumbaginaceae). Conservation Genetics 1(2): 177-179.
[PDF]

VanHam, R.C.H.J., F. González Candelas, F. Silva, A. Moya & A. Latorre. 2000. Post-symbiotic plasmid acquisition and evolution of the repA1-replicon in Buchnera aphidicola. Proceedings National Academy Sciences USA. 97(20): 10855-10860.
[PubMed] [PDF]

Sanchis, A., A. Latorre, F. González Candelas & J.M. Michelena. 2000. An 18S rDNA based molecular phylogeny of Aphidiinae (Himenoptera: Braconidae). Molecular Phylogenetics and Evolution 14 (2): 180-194.
[PubMed] [PDF]

Palacios, C., J.A. Rosselló & F. González Candelas. 2000. Study of the evolutionary relationships among Limonium species (Plumbaginaceae) using nuclear and cytoplasmic molecular markers. Molecular Phylogenetics and Evolution 14(2): 232-249.
[PubMed] [PDF]

Palacios, C., S. Kresovich & F. González Candelas. 1999. A population genetic study of the endandered plant species Limonium dufourii based on AFLPs. Molecular Ecology 8: 645-657.
[PDF]

Palacios, C. & F. González Candelas. 1997. Analysis of population genetic structure and variability using RAPD markers in the endemic and endangered Limonium dufourii (Plumbaginaceae). Molecular Ecology 6 (12): 1107-1121.
[PubMed] [PDF]

Phippen, W.B., S. Kresovich, F. González Candelas & J.R. McFerson. 1997. Molecular characterization can discriminate and partition variation among genebank holdings: a case study with phenotypically similar accessions of Brassica oleracea L. var. capitata (cabbage) 'Golden Acre'. Theoretical and Applied Genetics 94: 227-234.
[PDF]

Brown, S.M.; M.S. Hopkins, S.E. Mitchel, T.Y. Wang, S. Kresovich, R.R. Duncan, M.L. Senior & F. González Candelas. 1996. Multiple methods for the identification of polymorphic simple sequence repeats (SSRs) in sorghum [Sorghum bicolor (L.) Moench.?. Theor. Appl. Genet. 93: 190-198.
[PDF]

Elena, S.F., F. González-Candelas, I.S. Novella, E.A. Duarte, D.K. Clarke, E. Domingo, J.J. Holland & A. Moya. 1996. Evolution of fitness in experimental populations of Vesicular Stomatitis Virus. Genetics 142: 673-679.
[PubMed] [PDF]

Galiana, A., F. González Candelas y A. Moya. 1996. Postmating isolation analysis in founder-flush experimental populations of Drosophila pseudoobscura. Evolution 50 (2): 941-944.
[PDF]

González Candelas, F., S.F. Elena y A. Moya. 1995. Approximate variance of nucleotide divergence between two sequences when restriction fragment data are available. Genetics 140: 1443-1446.
[PDF]

Elena, S.F., F. González Candelas y A. Moya. 1992. Does the VP1 gene of foot-and-mouth disease virus behave as a molecular clock? Journal of Molecular Evolution 35: 223-229.
[PDF]

Martínez, M.A., Carrillo, C., González Candelas, F., Moya, A., Domingo, E. y Sobrino, F. 1991. Fitness alteration of foot-and-mouth disease virus mutants: measurement of the adaptability of viral quasispecies. Journal of Virology 65(7): 3954-3957.
[PDF]

Mueller, L.D., González Candelas, F. y Sweet, V.F. 1991. Components of density-dependent population dynamics: models and tests with Drosophila. The American Naturalist 137(4): 457-475.
[PDF]

 

Courses taught

Introduction to Evolutionary Theory (undergrad)

Population Genetics (advanced undergraduate)

Molecular Population Genetics (graduate)

Systematics, Classification and Phylogeny (graduate)

Biological Basis for Conservation (graduate)

Phylogenography and Population Structure (graduate)

Molecular Phylogenetics (graduate level)

Bioinformatics (graduate level)

 

Mailing address

            Instituto Cavanilles de Biodiversidad y Biología Evolutiva
            Universidad de Valencia
            APDO. 22085
            46071 - Valencia
            Spain

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