Dr. Jose M. Prieto-Garcia

M.Pharm., Ph.D. (Pharmacology), MSEP, MRSC, FHEA

Email: drprietojm@gmail.com | j.m.prietogarcia@ljmu.ac.uk | prietojm@uv.es
Websites: Google Scholar | ORCID | LinkedIn

Objective

A highly experienced pharmacology researcher and educator with a strong foundation in pharmacy, seeking to leverage my extensive background in drug discovery to contribute to and expand curricula across medical and allied healthcare sciences. Committed to delivering high-quality learning experiences, advancing pharmacological research, and supporting curriculum development for both undergraduate and postgraduate programs.

Professional Profile

Over 30 years of expertise in Pharmacology, Drug Discovery, and Analysis of Medicinal substances.
Advance HE Qualified University Teacher, Coordinator and Supervisor of both teaching and research activities.
Contribution to Pharmacy recruitment as Admissions tutor.
Strong research output (Q1 47%, 3*) and international footprint.
Capacity to attract funding for my research activities.

Education

Ph.D. (Pharmacology) - School of Pharmacy, University of Valencia, Spain (1994-2001)
Thesis: "Effects of Anti-inflammatory Plants on Leukocytes and oxidative processes" (Cum Laude)
Master in Pharmacy - School of Pharmacy, University of Valencia, Spain (1993-1994)
Dissertation: "Anti-inflammatory compounds from Haplophyllum hispanicum Spach" (Distinction)
Bachelor in Pharmacy - School of Pharmacy, University of Valencia, Spain (1986-1993)

Employment History

Associate Professor / Senior Lecturer, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK (2020-Present)
Assistant Professor / Lecturer B, School of Pharmacy, University College London, UK (2012-2020)
Lecturer, School of Pharmacy, University of London, UK (2006-2012)
Postdoctoral Research Fellow, School of Pharmacy, University of London, UK (2005-2006)
Postdoctoral Research Fellow, School of Pharmacy, University of Pisa, Italy (2001-2014)
Sciences Teacher, SAIT High School, Xàtiva, Spain (1995-1996)

Research Lines

My research focuses on several key areas within pharmacology and drug discovery:

RESEARCH INTEREST

Drug Discovery with Emphasis on Combinatorial Therapies Against Melanoma

Focuses on identifying and developing new therapeutic strategies, particularly combination therapies, to combat melanoma, a severe form of skin cancer.
Drug Interactions with Emphasis on Herb-Drug and Food-Drug Interactions

Investigates how herbal medicines and dietary components can interact with conventional drugs, understanding their pharmacokinetic and pharmacodynamic implications to ensure patient safety and optimize treatment outcomes.
Developing New AI Assisted Platforms for the Prediction of Pharmacological Properties of Complex Bioactive Products

Leverages artificial intelligence and in silico methods to predict the biological activities of complex natural products, accelerating the drug discovery process and improving the efficiency of compound screening.
In Vivo and In Vitro Studies on Anti-Inflammatory, Antioxidant and Anti-Infective Products with Emphasis on Skin Conditions

Conducts experimental studies (both in living organisms and in laboratory settings) to evaluate the effectiveness of natural compounds in treating inflammation, oxidative stress, and infections, especially those affecting the skin.

Publications

Summary: 1 Textbook; 6 Chapters; >75 Papers; >70 Communications. Metrics: (3,371 Citations; h-index 28; i10-index 53)

For a comprehensive list of all my publications, please download the full PDF:

Download Full List of Scientific Outputs (PDF)

Books

Heinrich, M., Barnes, J., Prieto-Garcia, J., Gibbons, S., & Williamson, E. M. (2024). Fundamentals of Pharmacognosy and Phytotherapy (4th ed.). London: Elsevier.

Book Chapters (Selected)

Stobart, A., Garcia, J.P., Vieweger, A., Westaway, S., Whistance, L., 2023. Medicinal tree products offer therapeutic benefits and potential diversification for small scale agroforestry and farm woodlands: An overview with indications for further studies, in: Medicinal Agroecology. CRC Press.
Jose M. Prieto, Andre L. D. A. Mazzari. 2022. Herb-Drug Interactions: Fundamental Mechanisms, Prevalence and Challenges in Their Identification., in: Barnes, J. (Ed.) Pharmacovigilance for Herbal and Traditional Medicines: Advances, Challenges and International Perspectives. Springer International Publishing AG, Cham, pp. 51-75.
Jose M. Prieto, Muna Ismail, Valentina Cattero, Moinuddin Amrelia, Scott Darby and Francis Evans Climate change in the Horn of Africa Drylands: domestication of Yeheb as a Climate-smart agricultural mitigation strategy to protect the regional food chain. In "Handbook of Climate Change Across the Food Supply Chain" Springer. (In press).
Silveira D., Prieto J.M., Freitas M.M., Mazzari A.L.D.A. (2018) Herbal Medicine and Public Healthcare: Current and Future Challenges. In: Cechinel Filho V. (eds) Natural Products as Source of Molecules with Therapeutic Potential. Springer, Cham.
Jose M. Prieto. "Artificial intelligence for the modelling and prediction of complex natural products bioactivities", In "Artificial Intelligence: Advances in Research and Applications", 2017, Pages 277-300. Ed. Luis Rabelo, Nova publishers, New York, ISBN: 9781536126785.
Pravit Akarasereenont, Marianne Jennifer Datiles, Natchagorn Lumlerdkij, Harisun Yaakob, Jose M. Prieto, Michael Heinrich. A Southeast Asian perspective on ethnopharmacology. In "Ethnopharmacology" 2015, ULLA Series, Pages 317-332. Ed. M. Heinrich and Anna Jäger, Elsevier Science B.V.: Amsterdam, ISBN 9781118930748.

Articles (Selected)

Shao, L., Zhao, Y., Heinrich, M., Prieto-Garcia, J.M., Manzoni, C., 2024. Active natural compounds perturb the melanoma risk-gene network. G3 (Bethesda) 14.
Prieto, J.M., Barker, A.M., Schaffner, U., Quetin-Leclercq, J., Braca, A., Boevé, J.-L., 2024. Furostanol saponins and ecdysteroids from plants of the genus Helleborus as phagostimulants and predator deterrents for larvae of two Monophadnus sawfly species. Plants 13, 2230.
Maiztegui, B., Villagarcía, H.G., Román, C.L., Flores, L.E., Prieto, J.M., Castro, M.C., Massa, M.L., Schinella, G.R., Francini, F., 2023. Dietary Supplementation with Yerba Mate (Ilex paraguariensis) Infusion Increases IRS-1 and PI3K mRNA Levels and Enhances Insulin Sensitivity and Secretion in Rat Pancreatic Islets. Plants (Basel) 12.
Dadé, M., Prieto-Garcia, J., Fancini, F., Schinella, G.R., 2024. Apoptotic activity of Boswellia carterii extract on human neutrophils. Journal of Natural Products Discovery 3.
Prieto, J.M., Hanafi, M.M.M., 2023. Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia. Curr Issues Mol Biol 45, 1536-1567.
Shao, L., González-Cardenete, M.A., Prieto-Garcia, J.M., 2023. In Vitro Cytotoxic Effects of Ferruginol Analogues in Sk-MEL28 Human Melanoma Cells. Int J Mol Sci 24.
Prieto-Garcia, J.M., Graham, L., Alkhabbaz, O., Mazzari, A.L.D.A., 2023. Potential Pharmacokinetic Interactions of Common Cardiovascular Drugs and Selected European and Latin American Herbal Medicines: A Scoping Review. Plants (Basel) 12.
Hanafi, M.M.M., Yaakob, H., Gibbons, S., Prieto, J.M., 2023. In Vitro Pro-Apoptotic and Anti-Migratory Effects of Marantodes pumilum (syn. Labisia pumila) Extracts on Human Prostate Cancer Cell Lines: Bioguided Isolation of 5-Henicosene-1-yl-resorcinol. Plants (Basel) 12.
Jalil, B., Naser, A.Y., M Prieto, J., Heinrich, M., 2022. Herbal supplements in Jordan: a cross-sectional survey of pharmacists' perspectives and knowledge. BMJ Open 12, e057405.
Mazzari, A.L.D.A., Lacerda, M.G., Milton, F.A., Mulin Montechiari Machado, J.A., Sinoti, S.B.P., Toullec, A.-S., Rodrigues, P.M., Neves, F. de A.R., Simeoni, L.A., Silveira, D., Prieto, J.M., 2022. In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity. Frontiers in Pharmacology 13, 826395.
Prieto, J.M., Schinella, G.R., 2022. Anti-Inflammatory and Antioxidant Chinese Herbal Medicines: Links between Traditional Characters and the Skin Lipoperoxidation "Western" Model. Antioxidants (Basel) 11.
Prieto-Garcia, J.M., 2022. Stability of Feverfew and its Active Principle Parthenolide: An Elusive Antimigraine Herbal Medicine. Journal of Natural Products Discovery 1.
Viteri, M.R., Fiebich, B.L., Prieto, J.M., Heinrich, M., 2022. Effects of important plant species of Teruel on the pro-inflammatory signalling cascade of human monocytes. Journal of Natural Products Discovery 1, 12-12.
Da-Costa-Rocha, I., Prieto, J.M., 2021. In Vitro Effects of Selective COX and LOX Inhibitors and Their Combinations with Antineoplastic Drugs in the Mouse Melanoma Cell Line B16F10. International Journal of Molecular Sciences 22.
AlQathama, A., Ezuruike, U. F., Mazzari, A. L. D. A., Yonbawi, A., Chieli, E., & Prieto, J. M. (2020). Effects of Selected Nigerian Medicinal Plants on the Viability, Mobility, and Multidrug-Resistant Mechanisms in Liver, Colon, and Skin Cancer Cell Lines. Frontiers in Pharmacology, 11.
AlQathama, A., Shao, L., Bader, A., Khondkar, P., Gibbons, S., & Prieto, J. M. (2020). Differential Anti-Proliferative and Anti-Migratory Activities of Ursolic Acid, 3-O-Acetylursolic Acid and Their Combination Treatments with Quercetin on Melanoma Cells. Biomolecules, 10(6), 894.

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