Animaciones multimedia
o Adhesion junction between cells. CD-ROM de Alberts et al, 2002, Vídeo
19-1. Vídeo que muestra células epiteliales
en cultivo que expresan cadherinas fusionadas a proteína fluorescente
verde. Se observa como se van creando uniones adherentes entre las células
a medida que aumenta la densidad celular del cultivo.
o Cell-Cell adhesion in leucocyte extravasation. CD-ROM de Lodish et
al, 2000, Focus Animation 22-4. Muestra la interacción
entre las diferentes proteínas de adhesión intercelular
(selectinas, integrinas de tipo beta-2, ICAMs) que median la extravasación
de leucocitos hacia zonas infectadas por bacterias.
o Calcium signaling through GAP junctions. CD-ROM de Alberts et al,
2002, Vídeo 15-1. Vídeo que muestra
células gliales en cultivo en presencia de un fluorescente dependiente
de calcio. Se observa que pequeñas cantidades de un neurotransmisor
producen ondas de calcio, que es transmitido entre células adyacentes
a través de uniones en GAP. |
Bibliografía complementaria
- Libros
BECKERLE, M.C. (2001) Cell Adhesion. Oxford University Press, Oxford.
CEREJIDO, M., ANDERSON, J. (2001) Tight Junctions. CRC Press.
HERTSBERG, E.L. y JOHNSON, R.G. (1988) Gap junctions. Alan R. Liss, Nueva
York.
PIGOTT, R. y POWER, C. (1993) The Adhesion Molecule Facts Book. Academic
Press, London.
STEVENSON, B.R., GALLIN, W.J. y PAUL, D.L. (1992) Cell-cell interactions:
A practical approach. Oxford University Press, Oxford.
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Bibliografía complementaria - Artículos
BENNET, M.V. et al. (1991) Gap junctions: new tools, new
answers, new questions. Neuron 6: 305-320.
CEREIJIDO, M. VALDÉS, J., SHOSHANI, L. y CONTERAS, R. (1998) Role
of tight junctions in establishing and maintaining cell polarity. Annu.
Rev. Physiol. 60: 161-177.
CHOTHIA, C. y JONES, E.Y. (1997) The molecular structure of cell adhesion
molecules. Annu.Rev. Biochem. 66: 823-862.
CHRISTOFORI, G. y SEMB, H. (1999) The role of the cell-adhesion molecule
E-cadherin as a tumor-suppressor gene. Trends Biochem. Sci. 24: 73-76.
DUNON, D., PIALI, L. y IMHOF, B.A. (1996) To stick or not to stick: the
new leucocyte homing paradigm. Curr. Opin. Cell Biol. 8: 714-723.
GREEN, K.J., y GAUDRY, C.A. (2000) Are desmosomes more than tethers for
intermediate filaments? Nat. Rev. Mol. Cell Biol. 1: 208-216.
GUMBINER, B.M. (1996) Cell adhesion: the molecular basis of tissue architecture
and morphogenesis. Cell 84: 345-357.
HUMPHRIES, M.J. y NEWHAM, P. (1998) The structure of cell-adhesion molecules.
Trends in Cell Biol. 8: 78-83.
HYNES, R.O. (1992) Specificity of cell adhesion in development: the cadherin
superfamily. Curr. Opin. Cell Biol. 2: 621-624.
KUMAR, N.M. y GILULA, N.B. (1996) The gap junction communication channel.
Cell 84: 381-388.
KELSELL, O.P., DUNLOP, J., Y HODGINS, M.B. (2001) Human diseases: clues
to cracking the connexin code? Trends Cell Biol. 11: 2-6.
KOCH, A.W., BOZIC, D., PERTZ, O. y ENGEL, J. (1999) Homophilic adhesion
by cadherins. Curr. Opin. Struct. Biol. 9: 275-281.
LASKY, L.A. (1992) Selectins: interpreters of cell-specific carbohydrate
information during inflammation. Science 258: 964-969.
LO, C. W. (1999) Genes, gene knockouts, and mutations in the analysis
of gap juntions. Dev. Genet. 24: 1-4.
MADARA, J.L. (1998) Regulation of the movement of solutes across tight
junctions. Annu. Rev. Physiol. 60: 143-159.
MITIC, L.L. y ANDERSON, J.M. (1998) Molecular architecture of tight juntions.
Annu. Rev. Physiol. 60: 121-142.
SIMON, A.M. y GOODENOUGH, D.A. (1998) Diverse functions of vertebrate
gap junctions. Trends Cell Biol. 8: 477-483.
STEVENSON, B.R. y KEON, B.H. (1998) The tight juntion: Morphology to molecules.
Annu. Rev. Cell Dev. Biol. 14: 89-109.
WHELAN, J. (1996) Selectin synthesis and inflammation. Trends Biochem.
Sci. 21: 65-69.
WORTHYLAKE, R.A. AND BURRIDGE, K. (2001) Leukocyte transendothelial migration:
orchestrating the underlying molecular machinery. Curr. Opin. Cell Biol.
13: 569-577.
YAP, A.S., BRIEHER, W.M. y GUMBINER, B.M. (1997) Molecular and functional
analysis of cadherin-based adherens junctions. Annu. Rev. Cell Dev. Biol.
13: 119-146.
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