García-López, A., Llamusi, B., Orzáez, M., Pérez-Payá E. and Artero R.
In vivo discovery of a peptide that prevents CUG RNA hairpin formation and reverses RNA toxicity in Myotonic Dystrophy models.
Proc. Natl. Acad. Sci. USA (in press).
Coll, C., Mondragón, L., Martínez-Máñez, R., Sancenón, F., Marcos, M.D., Soto, J., Amorós, P., Pérez-Payá E.
Click chemistry anchoring of peptide sequences for the design of enzyme-mediated controlled release systems based on silica mesoporous supports
Angewandte Chemie Int Ed 50(9), 2138-40 (2011)
Orzáez, M., Gortat, A., Sancho M., Carbajo, R.J., Pineda-Lucena, A., Palacios-Rodríguez, Y., Pérez-Payá, E.
Characterization of Dequalinium as a XIAP antagonist that targets the BIR2 domain
Apoptosis 10(5), 460-7 (2011)
Pérez-Payá, E., Orzáez, M., Mondragón, L., Wolan, D., Wells, J.A., Messeguer, A., Vicent, M.J.
Molecules that modulate Apaf-1 activity
Medicinal Research Reviews (in press) Jan 22 Epub ahead of print (2010)
Vicent, M.J., Cascales, L., Carbajo, R.J., Cortés, N., Messeguer, A. Pérez-Payá, E.
Nanoconjugates as intracorporeal neutralizers of bacterial endotoxins
J Control Release 142(2), 277-85 (2010)
García-Saez, A., Ries, J., Orzáez, M., Pérez-Payá, E., Schwille, P.
Lipid membranes promote tBid interaction with Bcl-xL.
Nature Structural and Molecular Biology 16(11), 1178-85 (2009)
Santamaría, B., Benito-Martín, A., Conrado, A., Aroeira, L., Reyero, A., Vicent, M.J., Orzaez, M., Celdrán, A., Esteban, J., Selgas, R., Ruiz-Ortega, M., López-Cabrera, M., Egido, J., Pérez-Payá, E., Ortíz, A.
A nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injury.
PLoS One. (2009) 4(8): e6634
Orzáez, M., Gortat, A., Mondragon, L., Pérez-Payá, E.
Peptides and peptide mimics as modulators of apoptotic pathways
ChemMedChem 4(2) 146-160 (2009)
Mondragón, L., Orzáez, M., Armiñán, M., Sanclimens, G., Sepúlveda, P., Messeguer, A., Vicent, M.J., Pérez-Payá, E.
Modulation of Cellular Apoptosis with Apaf-1 Inhibitors
J Med Chem 51(3) 521-529 (2008)
Canela, N., Orases, M., Fucho, R., Gutierrez, R., Pineda-Lucena, A., Bachs, O., Pérez-Payá, E.
Identification of an hexapeptide that binds to a surface pocket in cyclin A and inhibits the catalytic activity of the complex cyclin-dependent kinase 2/cyclinA
J Biol Chem 281(47) 35942-53 (2006)
Vicent M.J., Pérez-Payá, E.
PGA-aided inhibitors of Apaf-1: An Antiapoptotic Polymeric Nanomedicine
J Med Chem 49(13), 3763-5 (2006)
Malet, G., Martín, A.G., Orzáez, Vicent, M.J., M., Masip, I., Sanclimens, G., Mingarro, I., Ferrer-Montiel, Messeguer, A., Fearnhead, O., Pérez-Payá, E.
Small molecule inhibitors of Apaf-1-related caspasa-3/-9 activation that control mitochondrial-dependent apoptosis
Cell Death and Differentiation 13, 1523–1532 (2006)
Mora, P., Masip, I., Cortés, N., Marquina, R., Merino, R., Merino, J., Carbonell, C., Mingarro, I., Messeguer, A., Pérez-Payá, E.
Identification from a Positional Scanning Peptoid Library of in vivo Active Compounds that Neutralize Bacterial Endotoxins
J Med Chem 48, 1265-1268 (2005)
Pastor, M., De la Paz, M., Lacroix, E., Serrano, L., Pérez-Payá, E.
Combinatorial approaches: a new tool to search for highly structured -hairpin peptides
Proc. Natl. Acad. Sci. USA 99, 614-619 (2002)
García-Martinez, C., Humet, M., Planells-Cases, R., Merino, J.M., Sánchez-Baeza, F., Carbonell, T., Pérez-Payá, E., Belmonte, C., De Felipe, C., Messeguer, A., Ferrer-Montiel, A.V.
Identification of novel peptoid-based blockers of VR-1 that attenuate thermal hyperalgesia.
Proc. Natl. Acad. Sci. USA 99, 2374-2379 (2002)
Vilar, M., Esteve, V., Marcos, J. Pallás, V., Pérez-Payá, E.
Structural properties of carnation mottle virus p7 movement protein and its RNA-binding domain
J. Biol. Chem. 276, 18122-18129 (2001)
Taulés, M., Rodriguez, A., Rius, E., Estanyol, J.M:, Casanovas, O., Sacks, D.B., Pérez-Payá, E., Bachs, O., Agell, N.
Calmodulin binds to p21cip1 and is involved in the regulation of its nuclear localization
J. Biol. Chem. 274, 24445-24448. (1999)
Ferrer-Montiel, A.V., Merino, J.M., Blondelle, S.E., Pérez-Payá, E., Houghten, R.A., Montal, M.
Selected peptide targeted to the NMDA receptor channel protect neurons from excitotoxic death
Nature Biotech., 16(3), 286-291 (1998).
Pérez-Payá, E., Houghten, R.A., Blondelle, S.E.
Functionalized protein-like structures from conformationally defined synthetic combinatorial libraries
J. Biol. Chem. 271, 4120-4126. (1996)
Blondelle, S.E., Houghten, R.A., Pérez-Payá, E.
Identification of inhibitors of melittin using nonsupport-bound combinatorial libraries
J. Biol. Chem. 271, 4093-4099. (1996)
Pérez-Payá, E., Houghten, R.A., Blondelle, S.E.
The role of amphipathicity in the folding, self-association and biological activity of multiple subunit small proteins
J. Biol. Chem. 270, 1048-1056. (1995)
Marcos, J.F., Beachy, R.N., Houghten, R.A., Blondelle, S.E., Pérez-Payá, E.
Inhibition of a plant virus infection by analogs of melittin
Proc. Natl. Acad. Sci., USA 92, 12466-12469. (1995)