PUBLICACIONES RECIENTES

AUTORES: Joan Miquel Jordá-Gregori, Maria Eugenia González-Rosende, Patricia Cava-Montesinos  and José Sepúlveda-Arques 
TITULO: 1,3-0xazin-2-ones vs. Tetrahydrofurans by iodocyclisation of 2-alcoxycarbonylamino-3-alken-1-ols.
REF.REV: Tetrahedron Asymmetry.   En prensa  (2000)

AUTORES: Chakib Hajji, M. Luisa Testa, E. Zaballos garcia,, R. Salud-Bea, J. Srever Carrio, J. Sepulveda-Arques.
TITULO: Reaction of 3-methylamino-1,2-diols with dihalomethanes. Synthesis of chiral 4-substituted 3-methyltetrahydro-1,3-oxazinan-5-ols.
REF. REVISTA: Tetrahedron  56, 8173-8177, (2000)

AUTORES: Lourdes Rodriguez Salvador, Elena Zaballos Garcia, Eugenia Gonzalez Rosende. M. Testa, Jose Sepulveda Arques, R. Alan Jones.
TITULO: Thermolysis of 3-(Carbazol-3-yl)-2-azidopropenoates. 
REF. REVISTA: Tetrahedron 56, 4511-4514, (2000)

AUTORES: Alberto Acero Alarcón, Trinidad Armero Alarte, Joan Miquel Jordá Gregori, Cristina Rojas Argudo, Elena Zaballos García, Juan Server Carrió, Fatima Z. Ahyaje, José Sepúlveda Arques.
TITULO: Unusual ring closure reaction of amides on pyrimidines. Novel stereoselective synthesis of hexahydroimidazo [1,2-c]pyrimidines.
REF.REVISTA :   Synthesis , 2124-2130, (1999)

AUTORES:  Juan-Miquel Jordá Gregori, Mª Eugenia González Rosende, José Sepúlveda Arques, Roberta Galeazzi, Mario Orena.
TITULO: Highly regio- and stereoselective iodocyclization of chiral 3-alkoxycarbonyl-4-propenyl-2,2-dimethyl-1,3-oxazolidines: a computational investigation.
REF. REVISTA Tetrahedron Asymmetry 10, 1135-1143, 1999.

AUTORES: M.Eugenia Gonzalez-Rosende, José Sepúlveda-Arques, Elena Zaballos-Garcia,
 Luis R. Domingo, Ramón  J. Zaragozá, W. Brian Jennigs, Simon E. Lawrence and Donal O´Leary.
TITULO:Domino Reaction between 2-acylfurans and Diethyl azodicaraboxylate. 
A combined experimental, theoretical, X-ray and Dynamic NMR Study.
REF. REVISTA: J. C. S. Perkin Trans 2,  73,  (1999)                                                                     

PUBLICACIONES ANTERIORES

AUTORES :  M. Liu, F. Sanz, E. Gonzalez, O. Lozano, E. Zaballos, J. Sepúlveda.
TITULO : Ethyl N-Methyl-2-pyrrolylcarbonyl-hydrazinocarboxylate
REF.REVISTA :  Acta Crystalographica  C53, 492 (1997)

AUTORES :  E. Zaballos, E. Gonzalez, J.M. Jorda, J. Sepúlveda, W.B. Jennings, D.O´Leary, S. Twomey
TITULO : Ring transformation of furfural into an unusual bicyclic system:Characterisation and dinamic stereochemistry of 6,7-diethoxycarbonyl -(6,7) diaza-8-oxabicyclo (3,2,1) oct-3-en-2-one
REF.REVISTA :      Tetrahedron  53, 9313-9322 (1997)

AUTORES : E. Gonzalez, L.R. Domingo, J. Sepúlveda, D. Perona, E. Zaballos, A. Acero, B. Yruretagoyena
TITULO : Ring cleavage of 1-alkyl-2-aryl-3-(hydroxymethyl)pyrrolidines. A PM3 semiempirical study of molecular mechanism.
REF.REVISTA :  Journal Chemical Society. Perkin  Trans 2, 643-648, (1997)       	

AUTORES : L. Rodriguez, E. Zaballos, E. Gonzalez, M. Djebbouri, J. Sepulveda, A. Jones 
TITULO :  Synthesis and chemical reactivity of 5-methoxy-2-vinyl-4-azaindoles
REF.REVISTA :  Synthetic Communications   27 (8), 1439-1447, (1997)     	

AUTORES : J. Sepúlveda Arques, T. Armero Alarte, A. Acero Alarcón, E. Zaballos
 García, B. Yruretagoyena Solesio, J. Ezquerra Carrera. 
TITULO : Stereoselective Ring Transformation of N-Alkyl Aziridines into Oxazolidin-2-ones
REF.REVISTA :   Tetrahedron  52, 2097-2102 , (1996)                          

AUTORES : L. R. Domingo, A. Jones, M.T. Picher, J. Sepúlveda
TITULO : Theoretical Study of the reactions of 1-methyl-2-vinylpyrrole with methyl propiolate and with dimethyl acetylendicarboxylate
REF.REVISTA :  Journal of Molecular Structure 362, 209-213, (1996)     	

AUTORES :L.R. Domingo, R.A. Jones, M.T. Picher and J. Sepúlveda-Arques
TITULO :Theoretical Study of the Addition of Dimethylacetylenedicarboxylate to 1-Methyl-2-(1-substitutedvinyl) pyrroles 
REF.REVISTA:Tetrahedron  51, 8739-8747,  (1995) 

AUTORES : J. Sepúlveda-Arques, B. Abarca-Gonzalez and M. Medio-Simón 
TITULO : Cycloaddition Reactions with Vinyl Heterocycles
REF.REVISTA : Advances in Heterocyclic Chemistry  339-401, 63,  (1995)         	

AUTORES : M. E. Gonzalez-Rosende, O. Lozano-Lucia, E. Zaballos and J. Sepúlveda-Arques
TITULO : Reaction of N-Substituted 2-formylpyrroles with Azodicarbonylic compounds    
REF.REVISTA :    J. Chem. Research   (S) 260-261 (1995)	

AUTORES : E. Zaballos, L. R. Domingo, J. Sepúlveda, J. Ezquerra y B. Yruretagoyena 
TITULO : Ensayos de Hidrogenación de 4-alcoxicarbonil-4-pirrolidin-2-onas 5-sustituidas.
                Estudio semiempirico
REF.REVISTA : Anales de Quimica  594-598, 91, (1995)	

AUTORES : J. Sepúlveda-Arques, E. Gonzalez-Rosende, D. Perona Marmol, E. Zaballos
TITULO : Unusual Hofmann Elimination at Low Temperature. Reaction of 3-hydroxymethyl
                pyrrolidines with p-toluensulfonyl chloride
REF.REVISTA : Monatshefte fur Chemie 124, 323, (1993)        	

AUTORES : J. Sepúlveda, M. Medio, and E. Zaballos  
TITULO : Drug Synthesis through cycloaddition reactions
REF.REVISTA :  Il Farmaco 48, 195-207, (1993)       	

AUTORES : M. Pitarch-Vinuesa, M. A. Miranda, M. Medio-Simón, J. Sepúlveda  
TITULO : Electron transfer Reactions of 1-Phenyl-4-vinylpyrazole  Mediated by Cerium (IV)
                Ammonium Nitrate.
REF.REVISTA : Monatshefte fur Chemie 124, 959, (1993)   

AUTORES : J. Sepúlveda, E. Romero, M. E. Gonzalez, M. E. Zaballos 
TITULO : Reaction of Cycloimmonium ylides with DiethylAzodicarboxylate.
REF.REVISTA : Anales 88, 253, (1992).        	

AUTORES : S. Escrivá-Moscardó, J. Sepúlveda-Arques, B. Abarca, R. Ballesteros, S. García and  F. Gómez.   
TITULO : Reaction of 3-Formylindole N,N Dimethylhydrazone with Dienophiles. A Stereoselective  Addition.
REF.REVISTA : Heterocycles 34, 61, (1992).        	

AUTORES :  L. R: Domingo-Asensi y J. Sepúlveda-Arques.
TITULO : DataC13
REF.REVISTA : Seraphim, PC 410 , (1993).       	

AUTORES : J. Sepúlveda-Arques, M. E. Gonzalez and M. E. Zaballos 
TITULO : Reacción de Bencenoazopirroles con Azodicarboxilato de Dietilo
REF.REVISTA : Anales de Química 88, 246, (1992)        	

AUTORES : F. B. W: Dida, S. García, F. Gómez, R. A. Jones, E. pérez, J. Sepúlveda 
TITULO : The Reaction of 1-Methylindole with Diethylazodicarboxylate
REF.REVISTA : J. Chem. Research (S), 206-207, (1990)        	

AUTORES : C. Borras-Almenar, J. Sepúlveda-Arques, M. Medio-Simón, U. Pindur
TITULO : First Reactions of 1,4-Dimethylcarbazole-3-Carbaldehyde N, N-Dimethyl
               hydrazone with Carbo- and Azo-Dienophiles              
REF.REVISTA : Heterocycles 31, 1927, (1990)         	

AUTORES : B. Abarca, R. Ballesteros, E. Gonzalez, P. Sancho, J. Sepúlveda 
TITULO : Studies on Dimethylhydrazones of Heteroaryl Aldehydes. The Reactivity of 
 2-Formylfuran, 2-formylthiophene...
REF.REVISTA : Heterocycles 31,1811, (1990)       	

AUTORES : J. Sepúlveda, E. Romero, M. E. Gonzalez, R. Pérez and  M. López
TITULO : Unprecedented ring Cleavage in the reaction of 1-methyl-3-phenacyl  Benzimi-
                dazolium ylide with Diethyl Azodicarboxylate                    
REF.REVISTA : Recueil. Travaux. Chim. Pays Bas. 109, 410. (1990)        	

AUTORES :  J. Sepúlveda-Arques, M. J: Alvarez and M. Medio-Simón.
TITULO : Cycloaddition reaction of 5-Deutero-1-phenylpyrazole. Stereoselective Cis "Ene" 
                Reactions and Simplification of  NMR spectra.
REF.REVISTA : Monatshefte fur Chemie. 121, 81-84, (1990)        	

AUTORES :  M. Medio -Simon, M. J. Alvarez, and J. Sepúlveda-Arques
TITULO : Cycloaddition reactions with 1-phenyl-5-vinylpirazole
REF.REVISTA : J. Chem. Soc. Perkin Trans. I , 2749, (1990)        	

AUTORES :  B. Abarca, R. Jones, M. Medio, J. Quilez, J. Sepúlveda, E. Zaballos
TITULO : Synthesis and Characterizacion of 1-(1-Methyl-Imidazol-2-yl)Ethenes
REF.REVISTA : Synthetic Commun. 20 (3), 321-331, (1990)        

AUTORES :  J. Sepúlveda-Arques, M. Medio-Simon and L. Piqueres, Vidal.
TITULO : Cycloaddition Reactions of 1-Tert-Butyl-4-vinylpyrazole
REF.REVISTA : Monatshefte fur Chemie.  120, 1113 (1989)       	

AUTORES : M. E. Gonzalez, P. Sancho, C. Soriano, R. Ballesteros, B. Abarca, J. Sepúlveda. 
TITULO : The  Reactivity of 2-Formylthiophene, 1-methyl-2-formylpyrrole, Benzaaldehyde and 
                2-formylfurane, N,N-dimethylhydrazones with Dimethyl Acetylenedicarboxylate.
REF.REVISTA : Heterocycles 1227, 27, (1988)          	

AUTORES : M. Gonzalez, R.A. Jones J. Sepúlveda and E. Zaballos.  
TITULO : Pyrrole Studies XL Synthesis of 2- and 3- substituted 1-Methylindoles from   
                vinylpirroles.
REF.REVISTA : Synthetic Commun 18,1669, (1988)        	

AUTORES : F. H. Cano, C. Foces, T. Aznar, J. Sepúlveda, R. A. Jones  
TITULO : Structure of (1R-3R) and (1S-3S)-1-(Methylindol-2-yl)-1, 3 Diphenylbutano-1,3 diol
REF.REVISTA : Acta Cryst. 44, 583-584 (1988)        

AUTORES :  F. Fuentes, J. Sepúlveda, R. A. Jones
TITULO : Pyrrole Studies. Part 39. The Disparate Reactivity of 5,7-Dimethyl-6H-pyrrolo
 (3, 4-d)  Pyridazines with Acetylenic...
REF.REVISTA : J. Chem. Research (S) 356, (M) 3001-3007. (1987)        	

AUTORES :  F. Fuentes, J. Sepúlveda, R. A. Jones, P.A. Bates and M. B. Hurstshouse
TITULO : Pyrroles studies. Part 37 Characterisation of the Adduct derived from       
               5,6-Dimethyl-2-phenacyl-6H-pyrrolo [3,4-d-pyridazinium Bromide and Dimethyl          Acetylenedicarboxylate under Basic Conditions. An X -Ray Crystallographic Study
REF.REVISTA : J. Chem. Research (S) 354-355(M) 2901-2914, (1987).  

AUTORES :  M. Medio-Simón and J. Sepúlveda-Arques.
TITULO : Evidence of 1,4-Dipolar intermediates in the Reaction of 4-phenyl-1,2,4-Triazoline 3,5- dione with Alkenes by Steromutation of dimethyl maleate 
REF.REVISTA : J. Chem. Research (S) 384-385,  (1987)        	

AUTORES : T. Sanchis, J. Sepúlveda, E. Zaballos and R. A. Jones. 
TITULO : The Reaction of 1-Methyl-2-vinylindoles with 4-phenyl-1,2,4- Triazoline-3, 5-dione.
REF.REVISTA : Heterocycles. 26, 401-404,  (1987).        	

AUTORES :  J. Sepúlveda , C. Soriano, Roquet-Jalmar, R. Mestre and J. Riego.
TITULO : Addition of Organomagnesium Reagents to Ring Epoxy-Ketones. V. 4, 4 Dimethyl-2,3- Epoxyciclohexanone and 3,5,5 Trimethyl-2,5 epoxycyclohexanone
REF.REVISTA : Bull. Soc. Chim. France. 1, 189-92 (1987)        	

AUTORES : R. A. Jones, J. Sepúlveda E. Zaballos , P. Bates and M. Hurstshose 
TITULO : An Unprecedented Reaction of Diethylazodicarboxylate with imidazolium ylides
REF.REVISTA : J. Chem . Soc. Chem Commun . 1745 (1986)        	

AUTORES : M. Medio Simon, J. Sepúlveda 
TITULO : New Cycloaddition reactions of 1-phenyl-4-vynilpyrazoles.
REF.REVISTA : Tretrahedron 42, 6683-86 (1986)        	

AUTORES :  J. Sepúlveda and M. Medio.
TITULO : Evidence of 1,4-dipole intermediate the reaction of 1-phenyl-4-vinylpyrazole with PTAD           
REF.REVISTA : Thetrahedron Letters, 26, 6357, (1985).          	

AUTORES : T. Hernández, R. A. Jones, H. Dawes and J. Sepúlveda. 
TITULO : Pyrrole Studies.32. A Novel Ring-Cleavage Reaction of the Pyridazine Ring
During the Reaction of 6H-pyrrolo(3,4)-Pyridazines with DMAD.
REF.REVISTA : J. Chem. Research. (M) 1128.(1985).         	

AUTORES :  R. A. Jones, P. Fresneda (in part), T. Aznar, J. Sepúlveda-Arques
TITULO : The Reactivity of 2-vinylindoles with Dimethylacetylendicarboxylate.
REF.REVISTA : Tetrahedron, 40, 4837-42, (1985).	

AUTORES : T. Aznar, R.A. Jones, R. T. Sanchis and J. Sepúlveda-Arques  
TITULO : Pyrrole Studies. 33. The Reactions of 2-vinylpyrroles with Diethylazodicarboxylate.
REF.REVISTA : J. Chem. Research. (M) 1232-1240. (1985)        	

AUTORES :  G. Barrie, W. Hinz, R. A. Jones and J. Sepúlveda-Arques
TITULO : Utilization of C Spectroscopy for the identification of the E and Z  , - Unsaturated  Ester Ketones and Nitriles.   
REF.REVISTA : J. Chem. Research. (M) 2801-2821, (1984)         	

AUTORES :  R. A. Jones, T. Aznar J. Sepúlveda
TITULO : Pyrroles. XXVIII. The effect of steric hindrance upon reaction of 2-vinylpyrroles
                with DMAD. 
REF.REVISTA : J. Chem. Soc. (PI), 2541 (1984).       	

AUTORES : R. A. Jones, B. Abarca, J. Sepúlveda, J. Quilez, T. J. King 
TITULO : The reaction of 1-phenyl-4-vinylpirazole with DEAZD
REF.REVISTA : J. Chem. Soc. (PI), 1423 (1984)  GB       	

AUTORES : J. Sepúlveda, J. Tortajada, R. Mestres  
TITULO : Addition of organomagnesium reagents to ring epoxy-ketones. IV. Cis and trans
                R(+) pulegone oxides
REF.REVISTA :  Bull. Soc. Chim. France (7-8) 237 (1984) .     	

AUTORES : J. Sepúlveda, C. Soriano, R. Mestres, J. Sendra 
TITULO: Addition of organomagnesium reagents to ring epoxy-ketones. III.2,3-epoxyciclohexanone.
REF.REVISTA : Bull. Soc. Chim. France, (7-8) 241 (1983) ..        	

AUTORES : J.Sepúlveda, S. Soto, R. Mestres 
TITULO : Reactions of Grignard reagents with -epoxycyclopentanones. II. The opening of the  oxirane ring.        
REF.REVISTA : Bull. Soc. Chim. France (7-8),237 (1983) .        	

AUTORES : J. Sepúlveda S. Soto, R. Mestres 
TITULO : Reactions of Grignard reagents with -epoxycyclopentanones, estereoselective addition to the carbonyl  group 
REF.REVISTA : Bull. Soc. Chim. France, (7-8) 233 (1983) ..        	

AUTORES : J. M. Brittain, R.A. Jones, J. Sépulveda, T. Aznar 
TITULO : Pyrrole studies. 27. Utilization of 1-methyl-2-pyrrolyl lithium in the synthesis of 1-methyl-2-substituted pyrroles
REF.REVISTA : Synthetic Comm.,12 231-248 (1982).         	

AUTORES : R. A. Jones, J. Sepúlveda 
TITULO : Pyrrole studies. 25. The reactions of 1-methyl-2-vinylpyrrole with DMAD
REF.REVISTA : Tetrahedron, 37, 1597 (1981) .       	

AUTORES : R. A. Jones, M. P. Marriot, W. P. Rosenthal, J. Sepúlveda 
TITULO :  Pyrrole studies. 22. (4 +2) Cycloaddition reactions with vinylpyrroles.
REF.REVISTA : J. Org. Chem., 45, 4515 (1980) .    

AUTORES : J. Sepúlveda, C. polo, R. Mestres  
TITULO :  Acyclic aldehydes from cyclic terpenes. Preparation of (3R)-3, 7-dimethyl-7-methoxy- 6-oxooctanal from (+)-pulegone
REF.REVISTA : An. Quim., 75, 398 (1979) . 

AUTORES : J. Sepúlveda, J. M. Viguera, J, Sánchez - Parareda
TITULO : Aislamiento de Chalepensina y Chalepina de Ruta Montana
REF.REVISTA : An. Quim., 70, 1020 (1974), .        	

AUTORES : J. Sepúlveda, J. M. Viguera, J, Sánchez - Parareda. 
TITULO :  Bergapteno y psoraleno en Ruta Montana.
REF.REVISTA : An. Quim., 69, 365 (1973).     

AUTORES : J. M. Viguera, J. Sánchez - Parareda, J. Sepúlveda 
TITULO :  Aislamiento y caracterización de 1-sesamina de las hojas de Ruta Montana.
REF.REVISTA :  Grasas y Aceites ,  6, 21 (1970) .