PILAR DOMINGO CALAP
PI-Invest Cont Ramon y Cajal
PI-Invest Cont Ramon y Cajal
:
Department: Institute for Biological Systems Integration (I2SYSBIO)
Department: Institute for Biological Systems Integration (I2SYSBIO)
(9635) 43261
Subjects taught and teaching methods
Academic training
- LICENCIADA EN BIOLOGIA. UNIVERSIDAD DE VALENCIA. 10/07/2007 (Diploma / Degree / Activities).
- MASTER EN BIODIVERSIDAD. UNIVERSIDAD DE VALENCIA. 08/09/2008 (Diploma / Degree / Activities).
- Mutational Effects, Evolution and Adaptation in single stranded RNA and DNA bacteriophages. Instituto Cavanilles de Biodiversidad y Biología Evolutiva, Universidad de Valencia. (Ph.D.).
Journal Publications
- Sanjuán R.; Domingo-Calap P. (2016) Mechanisms of viral mutation. Cellular and Molecular Life Sciences, 73, p. 44343 . ISSN: 1420-682X
- C Sueur; M Solis; M Meddeb; E Soulier; P Domingo-Calap; Q Lepiller; R Freitag; S Bahram; S Caillard; H Barth; F Stoll-Keller; S Fafi-Kremer (2015) Toward standardization of BK virus monitoring: evaluation of the BK Virus R-gene kit for quantification of BK viral load in urine, whole blood and plasma specimens. Journal of Clinical Microbiology, 52, pp. 4298 - 4304 . ISSN: 0095-1137
- M Solis; M Meddeb; C Sueur; P Domingo-Calap; E Soulier; A Chabaud; P Perrin; B Moulin; S Bahram; F Stoll-Keller; S Caillard; H Barth; S Fafi-Kremer (2015) Sequence Variation in Amplification Target Genes and Standards Influences Interlaboratory Comparison of BK Virus DNA Load Measurement. Journal of Clinical Microbiology, 53, pp. 3842 - 3852 . ISSN: 0095-1137
- Geller, R.; Domingo-Calap, P.; Cuevas, J.M.; Rossolillo, P.; Negroni, M.; Sanjuán, R. (2015) The External domains of the HIV-1 envelope are a mutational cold spot. Nature Communications, 6, p. 8571 . ISSN: 2041-1723
- M Solis; A Velay; R Porcher; P Domingo-Calap; E Soulier; M Joly; M Meddeb; W Knack-Knack; B Moulin; S Bahram; F Stoll-Keller; H Barth; S Caillard; S Fafi-Kremer. BKV replication in kidney transplant recipients: towards an earlier marker? (2017) BKV replication in kidney transplant recipients: towards an earlier marker?. Transplant International, 30, p. 21 . ISSN: 0934-0874
- M Solis; A Velay; R Porcher; P Domingo-Calap; E Soulier; M Joly; M Meddeb; W Knack-Knack; B Moulin; S Bahram; F Stoll-Keller; H Barth; S Caillard; S Fafi-Kremer. (2017) Neutralizing Antibody-Mediated Response and Risk of BK Virus-Associated Nephropathy. Journal of the American Society of Nephrology. ISSN: 1046-6673
- M Solis; A Velay; R Porcher; P Domingo-Calap; E Soulier; M Joly; M Meddeb; W Kack-Kack; B Moulin; S Bahram; F Stoll-Keller; H Barth; S Caillard; S Fafi-Kremer. (2016) Anti-BK virus neutralizing antibody titers before transplantation predict BK virus replication in kidney transplant recipients after transplantation. Journal of Clinical Virology, 82, p. s6 . ISSN: 1386-6532
- P Domingo-Calap; P Georgel; S Bahram. (2016) Back to the future: bacteriophages as promising therapeutic tools. Hla, 87, pp. 133 - 140 . ISSN: 2059-2302
- M Solis; M Meddeb; C Sueur; P Domingo-Calap; E Soulier; A Chabaud; P Perrin; B Moulin; S Bahram; F Stoll-Keller; S Caillard; H Barth; S Fafi-Kremer. (2016) Interlaboratory comparison of BK virus DNA load measurement: impact of viral polymorphism. Transplant International, 29, p. 11 . ISSN: 0934-0874
- M Solis; M Meddeb; C Sueur; P Domingo-Calap; E Soulier; A Chabaud; P Perrin; B Moulin; S Bahram; S Caillard; F Stoll-Keller; S Fafi-Kremer. (2015) Interlaboratory comparison of BK virus in DNA load assays. Journal of Clinical Virology, 70, p. S114 . ISSN: 1386-6532
- Pilar Domingo-Calap; Jennifer Delgado-Martínez (2018) Bacteriophages: Protagonists of a Post-Antibiotic Era. Antibiotics-Basel, 7(66) . ISSN: 2079-6382
- Domingo-Calap,P.; Schubert,B.; Joly,M.; Solis,M.; Untrau,M.; Muller,C.; Le Gentil,M.; Michel,S.; Carapito,R.; Georgel,P.; Caillard,S.; Fafi-Kremer,S.; Kohlbacher,O.; Paul,N.; González-Candelas,F.; Bahram,S. (2018) An unusually high substitution rate for transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides. PLOS Pathogens, 14(10), p. e1007368 . ISSN: 1553-7366
- Pilar Domingo-Calap; Juan Vicente Bou (2018) A Method for Isolation of the Virome from Plasma Samples. Methods in Molecular Biology, 1838 . ISSN: 1064-3745
- Pilar Domingo-Calap, Ernesto Segredo-Otero, María Durán-Moreno and Rafael Sanjuán (2019) Social evolution of innate immunity evasion in a virus. Nature Microbiology. ISSN: 2058-5276
- María Cebriá-Mendoza; Rafael Sanjuán; Pilar Domingo-Calap (2019) Directed evolution of a mycobacteriophage. Antibiotics-Basel, 8, p. E46 . ISSN: 2079-6382
- Pilar Domingo-Calap (2019) Viral Evolution and Immune Responses. Journal of Clinical Microbiology and Biochemical Technology, 5, pp. 13 - 18 . ISSN: 2581-527X
- Ezequiel Monferrer; Pilar Domingo-Calap (2019) Virus-Host Coevolution as a Tool for Controlling Bacterial Resistance to Phage Therapy. Journal of Biotechnology and Biomedicine, 2, pp. 096 - 104 . ISSN: 2642-9128
- Domingo-Calap, Pilar; Beamud, Beatriz; Vienne, Justine; González-Candelas, Fernando; Sanjuán, Rafael (2020) Isolation of four lytic phages infecting Klebsiella pneumoniae K22 clinical isolates from Spain. International Journal Of Molecular Sciences, 21(2), p. 425 . ISSN: 1661-6596
- Domingo-Calap, Pilar; Beamud, Beatriz; Mora,L.; González-Candelas, Fernando; Sanjuán, Rafael (2020) Isolation and characterization of two Klebsiella pneumoniae phages encoding divergent depolymerases. International Journal Of Molecular Sciences, 21(9), p. 3160 . ISSN: 1661-6596
- Pilar Domingo-Calap; Lucas Mora-Quilis; Rafael Sanjuán (2020) Social Bacteriophages. Microorganisms, 8, p. 533 . ISSN: 2076-2607
- Walter Randazzo; Enric Cuevas-Ferrando; Rafael Sanjuán; Pilar Domingo-Calap; Gloria Sánchez (2020) Metropolitan wastewater analysis for COVID-19 epidemiological surveillance. International Journal of Hygiene and Environmental Health, 230, p. 113621 . ISSN: 1438-4639
- Celia Ferriol-González; Pilar Domingo-Calap (2020) Phages for biofilm removal. Antibiotics-Basel, 9, p. 268 . ISSN: 2079-6382
- Beatriz Gutierrez; Pilar Domingo-Calap (2020) Phage therapy in gastrointestinal diseases. Microorganisms, 8, p. 1420 . ISSN: 2076-2607
- Alsaadi, A.; Beamud, B.; Easwaran, M.; Abdelrahman, F.; El-Shibiny, A.; Alghoribi, M.F.; Domingo-Calap, P. (2021) Learning from mistakes: the role of phages in pandemics. Frontiers In Microbiology. ISSN: 1664-302X
- Albert S; Ruíz A; Pemán J; Salavert M; Domingo-Calap P (2021) Lack of evidence for infectious SARS-CoV-2 in feces and sewage. European Journal of Clinical Microbiology & Infectious Diseases. ISSN: 0934-9723
- Pilar Domingo-Calap (2018) Phages as Promising Biomedical Tools. Biomedical Journal of Scientific & Technical Research. ISSN: 2574-1241
- Ahmed Al-Zaher; Pilar Domingo-Calap; Rafael Sanjuan (2021) Experimental virus evolution in cancer cell monolayers, spheroids, and tissue explants. Virus Evolution. ISSN: 2057-1577
- Olga Pacios; Laura Fernández-García; Inés Bleriot; Lucia Blasco; Antón Ambroa; María López; Concha Ortiz-Cartagena; Felipe Fernández Cuenca; Jesús Oteo-Iglesias; Álvaro Pascual; Luis Martínez-Martínez; Pilar Domingo-Calap; María Tomás (2021) Phenotypic and Genomic Comparison of Klebsiella pneumoniae Lytic Phages: vB_KpnM-VAC66 and vB_KpnM-VAC13. Viruses. ISSN: 1999-4915
- Celia Ferriol-González; Pilar Domingo-Calap (2021) Phage Therapy in Livestock and Companion Animals. Antibiotics-Basel. ISSN: 2079-6382
- María-Carmen Marqués; Raúl Ruiz; Roser Montagud-Martínez; Rosa Márquez-Costa; Sandra Albert; Pilar Domingo-Calap; Guillermo Rodrigo (2021) CRISPR-Cas12a-Based Detection of SARS-CoV‑2 Harboring the E484K Mutation. Acs Synthetic Biology. ISSN: 2161-5063
- Olga Pacios; Laura Fernández-García; Ines Bleriot; Lucia Blasco; Mónica González-Bardanca; María López; Felipe Fernández Cuenca; Jesús Oteo; Álvaro Pascual; Luis Martínez-Martínez; Pilar Domingo-Calap; German Bou; María Tomás (2021) Enhanced Antibacterial Activity of Repurposed Mitomycin C and Imipenem in Combination with the Lytic Phage vB_KpnMVAC13 against Clinical Isolates of Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy. ISSN: 0066-4804
- Rafael Sanjuán; Pilar Domingo-Calap (2021) Reliability of Wastewater Analysis for Monitoring COVID-19 Incidence Revealed by a Long-Term Follow-Up Study. Frontiers in Virology. ISSN: 2673-818X
- Maria Luisa Domingo-Calap; Mireia Bernabeu-Gimeno; Cristina M Aure; Ester Marco-Noales; Pilar Domingo-Calap (2022) Comparative Analysis of Novel Lytic Phages for Biological Control of Phytopathogenic Xanthomonas spp. Microbiology Spectrum. ISSN: 2165-0497
- Roberto Vázquez; Roberto Díez-Martínez; Pilar Domingo-Calap; Pedro García; Diana Gutiérrez; Maite Muniesa; María Ruiz-Ruigómez; Rafael Sanjuán; María Tomás; María Ángeles Tormo-Mas; Pilar García (2022) Essential Topics for the Regulatory Consideration of Phages as Clinically Valuable Therapeutic Agents: A Perspective from Spain. Microorganisms, 10, p. 717 . ISSN: 2076-2607
- Pilar Domingo-Calap; Celia Ferriol-González (2022) Fagos como herramientas biomédicas contra superbacterias. Genética Médica y Genómica. ISSN: 2605-0501
- Ines Bleriot; Lucia Blasco; Olga Pacios; Laura Fernandez-Garcia; Anton Fernandez; Maria Lopez; Monica Gonzalez-Bardanca; Felipe Fernandez-Cuenca; Jesús Oteo; Alvaro Pascual; Luis Martinez-Martinez; Pilar Domingo-Calap; Thomas K. Wood; Maria Tomas (2022) PemIK (PemK/PemI) type II TA system from Klebsiella pneumoniae clinical strains 2 inhibits lytic phage. Scientific Reports. ISSN: 2045-2322
- Pilar Domingo-Calap (2022) Los Virus de las Bacterias. Mètode - Revista de la Universitat de València. ISSN: 1133-3987
- Marco Pardo-Freire; Pilar Domingo-Calap (2022) Phages and nanotechnology: new insights against multi-drug resistant bacteria. BioDesign Research. ISSN: 2693-1257
- Beamud, Beatriz; García-González, Neris; Gómez-Ortega, Mar; González-Candelas, Fernando; Domingo-Calap, Pilar; Sanjuán, Rafael (2023) Genetic determinants of host tropism in Klebsiella phages. Cell Reports, 42(2), p. 112048 . ISSN: 2211-1247
- Noelia Losada-Garcia; Angela Vazquez-Calvo; David Ortega-Alarcon; Olga Abian; Adrian Velazquez-Campoy; Pilar Domingo-Calap; Antonio Alcami; Jose M. Palomo (2023) Nanostructured biohybrid material with wide-ranging antiviral action. Nano Research. ISSN: 1998-0124
- Clara Ortega-Nieto; Noelia Losada-Garcia; Benevides C. Pessela; Pilar Domingo-Calap; Jose M. Palomo (2023) Design and Synthesis of Copper Nanobiomaterials with Antimicrobial Properties. ACS BIO & MED CHEM AU. ISSN: 2694-2437
- Maria Lavilla; Pilar Domingo-Calap; Sandra Sevilla-Navarro; Amaia Lasagabaster (2023) Natural Killers: Opportunities and Challenges for the Use of Bacteriophages in Microbial Food Safety from the One Health Perspective. Foods. ISSN: 2304-8158
- Marco Pardo-Freire; Pilar Domingo-Calap (2023) Phages and Nanotechnology: New Insights against Multidrug-Resistant Bacteria. BioDesign Research. ISSN: 2693-1257
- Noelia Losada-Garcia; Angela Vazquez-Calvo; David Ortega-Alarcon; Olga Abian; Adrian Velazquez- Campoy; Pilar Domingo-Calap; Antonio Alcami; and Jose M. Palomo (2023) Nanostructured biohybrid material with wide-ranging antiviral action. Nano Research. ISSN: 1998-0124
- Clara Ortega-Nieto; Noelia Losada-Garcia; Benevides C. Pessela; Pilar Domingo-Calap; Jose M. Palomo (2023) Design and Synthesis of Copper Nanobiomaterials with Antimicrobial Properties. ACS BIO & MED CHEM AU. ISSN: 2694-2437
- Maria Lavilla; Pilar Domingo-Calap; Sandra Sevilla-Navarro; Amaia Lasagabaster (2023) Natural Killers: Opportunities and Challenges for the Use of Bacteriophages in Microbial Food Safety from the One Health Perspective. Foods. ISSN: 2304-8158
- Arnau, Vicente; Díaz-Villanueva, Wladimiro; Mifsut Benet, Jorge; Villasante, Paula; Beamud, Beatriz; Mompó, Paula; Sanjuan, Rafael; González-Candelas, Fernando; Domingo-Calap, Pilar; Dzunková, Mária (2023) Inference of the life cycle of environmental phages from genomic signature distances to their hosts. Viruses, 15(5), p. 1196 . ISSN: 1999-4915
- Robby Concha-Eloko; Pilar Barberán-Martínez; Rafael Sanjuán; Pilar Domingo-Calap (2023) Broad-range capsule-dependent lytic Sugarlandvirus against Klebsiella sp. Microbiology Spectrum. ISSN: 2165-0497
- Pilar Domingo-Calap (2023) Fagos como Herramientas Biomédicas en la Lucha contra Bacterias Resistentes. Virología: Publicación Oficial de la Sociedad Española de Virología. ISSN: 2172-6523
Previous Tasks
- Curso: Técnicas de Análisis de Cromosomas y Ácidos Nucleicos. Servef. 2005 - 2005.
- Postdoc. Instituto de Hematología e Inmunología, Universidad de Estrasburgo. 01/01/2013 - 31/08/2016.
- doctorando. Instituto Cavanilles de Biodiversidad y Biología Evolutiva. 01/09/2008 - 31/08/2012.
- estancia predoctoral. Insituto de Biología Molecular y Celular, Universidad de Estrasburgo. 01/05/2011 - 31/08/2011.
- estancia predoctoral. Insituto de Biología Molecular y Celular, Universidad de Estrasburgo. 01/05/2012 - 31/08/2012.
- Juan de la Cierva Incorporación. Instituto de Biología Integrativa de Sistemas (Universitat de València-CSIC). 01/11/2016 - 31/10/2018.
- Postdoc Senior. Instituto de Biología Integrativa de Sistemas (Universitat de València-CSIC). 01/11/2018 - 30/11/2020.
Activity interests
- Epidemiología viral-ambiental Monitorización de ambientes naturales y antropogénicos para la vigilancia de enfermedades, especialmente brotes virales. Instituto de Biología Integrativa de Sistemas. . (01/12/2020).
- Aplicaciones biomédicas de bacteriófagos Desarrollo de bacteriófagos como herramientas biomédicas alternativas en la lucha contra bacterias multirresistentes, incluyendo su uso en diagnóstico, prevención y terapia. Aislamiento y caracterización de nuevos bacteriófagos, evolución dirigida para su optimización, emergencia de resistencias y nanotecnología. Instituto de Biología Integrativa de Sistemas (Universitat de València-CSIC). . (01/12/2020).
- Concienciación ciudadana de la emergencia de bacterias multiresistentes a antibióticos y necesidad de tratamientos alternativos. Terapia de fagos como herramienta de biocontrol desde una aproximación One Health. Instituto de Biología Integrativa de Sistemas (Universitat de València-CSIC). . (01/12/2020).
Projects
- ISOLATION AND CHARACTERIZATION OF NOVEL KLEBSIELLA PNEUMONIAE PHAGES AS A TOOL FOR PHAGE THERAPY AGAINST RESISTANT STRAINS (ISOLATION) (). 2020 - 2021. ESCMID. Sociedad Europea de Microbiología y Enfermedades Infecciosas. . PI: Pilar Domingo Calap.
- DETERMINACIÓN DE LA PRESENCIA DE SARS-COV-2 EN MUESTRAS AMBIENTALES Y SU POTENCIAL TRANSMISIÓN INDIRECTA (). 2020 - 2021. PROYECTO DE INVESTIGACIÓN DE SALUD, ISCIII, MINECO, MADRID, ESPAÑA. . PI: Pilar Domingo Calap.
- DOTACIO ADICIONAL AJUDAS PROGRAMA DE AYUDAS RAMON Y CAJAL 2019 (). 2020 - 2025. MINECO. Ministerio de Economía y Competitividad. . PI: Pilar Domingo Calap.
- Evolución Dirigida de Virus Oncolíticos (). 2018 - 2020. MINISTERIO DE CIENCIA, INNOVACIÓN Y UNIVERSIDADES. . PI: Rafael Sanjuán.
- Collective Infectious Units and the Social Evolution of Viruses (). 2017 - 2022. European Research Council. . PI: Rafael Sanjuán Verdeguer.
- Vigilancia epidemiológica del COVID-19 en aguas residuales (). 2020. Generalitat Valenciana. . PI: Rafael Sanjuán.
- VALIDACION DE LA ACCION VIRUCIDA DEL MATERIAL VIRUCLEAN_T2 CONTRA CORONAVIRUS EN MUESTRAS DE TEJIDO DE PES PARA COLCHON ECOPURE (). 2020. COLCHONES DELAX S.L.. . PI: Rafael Sanjuán; Pilar Domingo-Calap.
- ESTABILIDAD DE CORONAVIRUS EN CONTACTO CON DIFERENTES MATERIALES (). 2020. Asociación de la Industria Navarra. . PI: Rafael Sanjuán; Pilar Domingo-Calap.
- ESTABILIDAD DE CORONAVIRUS EN DIFERENTES MATERIALES (). 2020. Instituto Tecnologico del Embalaje, Transporte y Logística - ITENE. . PI: Rafael Sanjuán; Pilar Domingo-Calap.
- AISLAMIENTO, CARACTERIZACION Y VALIDACION DE FAGOS PARA EL TRATAMIENTO DE LA MASTITIS BOVINA (). 2020. Laboratorios Hipra, S.A.. . PI: Rafael Sanjuán; Pilar Domingo-Calap.
Thesis, minor thesis and research reports
- Iván Andreu Moreno, (2016). Análisis de la Distribución de Mutaciones Espontáneas en el Genoma del Virus de la Hepatitis C. (Master Thesis). Universitat de València..
- María Cebrián Mendoza, (2017). Evolución Experimental de Micobacteriófagos. (Master Thesis). Universitat de València..
- Amanda García Martínez, (2020). Búsqueda y caracterización de bacteriófagos de Staphylococcus presentes en la microbiota de la piel. (Master Thesis). ..
- Beatriz Gutierrez Lopez, (2020). Bacteriófagos: componentes y reguladores dinámicos de la microbiota intestinal. (Final Degree work). ..
- Pilar Barberán Martínez, (2020). Aislamiento y caracterización fenotípica de fagos líticos contra los 77 tipos capsulares de referencia de Klebsiella sp. (Final Degree work). ..
- Carlos Selles, (2022). Una aproximación a la fagoterapia: aislamiento de micobacteriófagos contra Mycobacterium abscessus multirresistentes. (Final Degree work). ..
- Mar Balanzá, (2022). Bacteriófagos como herramienta de biocontrol frente a la bacteria fitopatógena Xylella fastidiosa. (Master Thesis). ..
- Mieke Dejonghe, (2022). Isolating bacteriophages for the treatment of antibiotic-resistant Mycobacterium species. (Final Degree work). ..
- Casper Van der Hert, (2022). Isolation and characterization of novel bacteriophages for the treatment of diseases related to antibiotic resistant Mycobacterium strains. (Final Degree work). ..
- Marco Pardo, (2022). Síntesis y optimización de micropartículas para su empleo en terapia fágica. (Master Thesis). ..
© 2024 UV. - Av. Blasco Ibáñez, 13. 46010 Valencia. Spain. UV phone +34 963 86 41 00