Profile

Varea E, Ponsoda X, Molowny A, Danscher G, Lopez-Garcia C. (2001) Imaging synaptic zinc release in living nervous tissue . Journal of Neuroscience Methods, 110, pp. 57 - 63 . ISSN: 0165-0270

Wang ZY, Li JY, Varea E, Danscher G, Dahlström A. (2001) Is the postganglionic sympathetic neuron zinc-enriched? A stop-flow nerve crush study on rat sciatic nerve. . Neuroreport, 12, pp. 2247 - 2250 . ISSN: 0959-4965

Danscher G, Jo SM, Varea E, Wang Z, Cole TB, Schrøder HD. (2001) Inhibitory zinc-enriched terminals in mouse spinal cord. . Neuroscience, 105, pp. 941 - 947 . ISSN: 0306-4522

Nacher J, Soriano S, Varea E, Molowny A, Ponsoda X, Lopez-Garcia C. (2002) CRMP-4 expression in the adult cerebral cortex and other telencephalic areas of the lizard Podarcis hispanica. Developmental Brain Research, 139(2), pp. 285 - 294 . ISSN: 0165-3806

Lopez-Garcia C, Varea E, Palop JJ, Nacher J, Ramirez C, Ponsoda X, Molowny A. (2002) Cytochemical techniques for zinc and heavy metals localization in nerve cells. Microscopy Research and Technique, 56(5), pp. 318 - 331 . ISSN: 1059-910X

Nacher J, Varea E, Blasco-Ibanez JM, Castillo-Gomez E, Crespo C, Martinez-Guijarro FJ, McEwen BS. (2005) Expression of the transcription factor Pax6 in the adult rat dentate gyrus. Journal of Neuroscience Research, 81(6), pp. 753 - 61 . ISSN: 0360-4012

Varea E, Nacher J, , Blasco-Ibanez JM, Gomez-Climent MA, Castillo-Gomez E, Crespo C, Martinez-Guijarro FJ. (2005) PSA-NCAM expression in hte rat medial prefrontal cortex. Neuroscience, 136(2), pp. 435 - 443 . ISSN: 0306-4522

Gutierrez-Mecinas, M.; Crespo, C.; Blasco-Ibanez, J.M.; Gracia-Llanes, F.J.; Marques-Mari, A.I.; Nacher, J.; Varea, E.; Martinez-Guijarro, F.J. (2005) Distribution of D2 dopamine receptor in the olfactory glomeruli of the rat olfactory bulb. European Journal of Neuroscience, 22(6), pp. 1357 - 1367 . ISSN: 0953-816X

Varea, E.; Alonso-Llosà, G.; Molowny, A.; Lopez-Garcia, C.; Ponsoda, X. (2006) Capture of extracellular zinc ions by astrocytes. Glia, 54(4), pp. 304 - 315 . ISSN: 0894-1491

Frederickson CJ, Giblin LJ 3rd, Balaji RV, Masalha R, Frederickson CJ, Zeng Y, Lopez EV, Koh JY, Chorin U, Besser L, Hershfinkel M, Li Y, Thompson RB, Krezel A. (2006) Synaptic release of zinc from brain slices: factors governing release, imaging, and accurate calculation of concentration.. Journal of Neuroscience Methods, 154, pp. 19 - 29 . ISSN: 0165-0270

Gutièrrez-Mecinas M, Crespo C, Blasco-Ibáñez JM, Nácher J, Varea E, Martínez-Guijarro FJ, (2007) Migrating neuroblasts of the rostral migratory stream are putative targets for the action of nitric oxide. European Journal of Neuroscience, 26, pp. 392 - 402 . ISSN: 0953-816X

Varea E, Blasco-Ibáñez JM, Gómez-Climent MA, Castillo-Gómez E, Crespo C, Martínez-Guijarro FJ, Nácher J (2007) Chronic fluoxetine treatment increases the expression of PSA-NCAM in the medial prefrontal cortex. Neuropsychopharmacology, 32(4), pp. 803 - 812 . ISSN: 0893-133X

Nácher J, Varea E, Blasco-Ibáñez JM, Gómez-Climent MA, Castillo-Gómez E, Crespo C, Martínez-Guijarro FJ, McEwen BS (2007) NMDA receptor expression during adult neurogenesis in the rat dentate gyrus. Neuroscience, 144(3), pp. 855 - 864 . ISSN: 0306-4522

E. Varea, E. Castillo-Gómez, M.A. Gómez-Climent, J.M. Blasco-Ibáñez, C. Crespo, F.J. Martínez-Guijarro, J. Nàcher (2007) Chronic antidepressant treatment induces contrasting patterns of synaptophysin and PSA-NCAM expression in different regions of the adult rat telencephalon. European Neuropsychopharmacology, 17(8), pp. 546 - 557 . ISSN: 0924-977X

E. Varea, E. Castillo-Gómez, M.A. Gómez-Climent, J.M. Blasco-Ibáñez, C. Crespo, F.J. Martínez-Guijarro, J. Nàcher (2007) PSA-NCAM expression in the human prefrontal cortex. Journal of Chemical Neuroanatomy, 33(4), pp. 202 - 209 . ISSN: 0891-0618

Lopez-Fernandez MA, Montaron MF, Varea E, Rougon G, Venero C, Abrous DN, Sandi C. (2007) Upregulation of polysialylated neural cell adhesion molecule in the dorsal hippocampus after contextual fear conditioning is involved in long-term memory formation. . Journal of Neuroscience, 27, pp. 4552 - 4561 . ISSN: 0270-6474

Sandi C, Cordero MI, Ugolini A, Varea E, Caberlotto L, Large CH. (2008) Chronic stress-induced alterations in amygdala responsiveness and behavior--modulation by trait anxiety and corticotropin-releasing factor systems. . European Journal of Neuroscience, 28, pp. 1836 - 1848 . ISSN: 0953-816X

Castillo-Gómez E, Gómez-Climent MA, Varea E, Guirado R, Blasco-Ibáñez JM, Crespo C, Martínez-Guijarro FJ, Nácher J. (2008) Dopamine acting through D2 receptors modulates the expression of PSA-NCAM, a molecule related to neuronal structural plasticity, in the medial prefrontal cortex of adult rats. Experimental Neurology. ISSN: 0014-4886

Gomez-Climent MA, Castillo-Gomez E, Varea E, Guirado R, Blasco-Ibañez JM, Crespo C, Martinez-Guijarro, FJ, Nacher J (2008) A Population of Prenatally Generated Cells in the Rat Paleocortex Maintains an Immature Neuronal Phenotype into Adulthood. Cerebral Cortex, 18(10), pp. 2229 - 2240 . ISSN: 1047-3211

Borcel E, Pérez-Alvarez L, Herrero AI, Brionne T, Varea E, Berezin V, Bock E, Sandi C, Venero C. (2008) Chronic stress in adulthood followed by intermittent stress impairs spatial memory and the survival of newborn hippocampal cells in aging animals: prevention by FGL, a peptide mimetic of neural cell adhesion molecule. . Behavioural Pharmacology, 19, pp. 41 - 49 . ISSN: 0955-8810

Gutièrrez-Mecinas M, Blasco-Ibáñez JM, Nàcher J, Varea E, Martínez-Guijarro FJ, Crespo C. (2008) Distribution of the A3 subunit of the cyclic nucleotide-gated ion channels in the main olfactory bulb of the rat. Neuroscience, 153(4), pp. 1164 - 1176 . ISSN: 0306-4522

Varea E, Castillo-Gomez E, Gomez-Climent MA, Guirado R, Blasco-Ibanez JM, Crespo C, Martinez-Guijarro FJ, Nacher J. (2009) Differential evolution of PSA-NCAM expression during aging of the rat telencephalon. Neurobiology of Aging, 30, pp. 808 - 818 . ISSN: 0197-4580

Guirado R, Varea E, Castillo-Gomez E, Gomez-Climent MA, Rovira-Esteban L, Blasco-Ibanez JM, Crespo C, Martinez-Guijarro FJ, Nacher J. (2009) Effects of chronic fluoxetine treatment on the rat somatosensory cortex: activation and induction of neuronal structural plasticity. Neuroscience Letters, 457, pp. 12 - 15 . ISSN: 0304-3940

D. Pérez-Cremades ¿ S. Hernández ¿ J. M. Blasco-Ibáñez ¿ C. Crespo ¿ J. Nacher ¿ E. Varea (2010) Alteration of inhibitory circuits in the somatosensory cortex of Ts65Dn mice, a model for Down's syndrome. Journal of Neural Transmission, 117, pp. 445 - 455 . ISSN: 0300-9564

Berbel P, Navarro D, Ausó E, Varea E, Rodríguez AE, Ballesta JJ, Salinas M, Flores E, Faura CC, de Escobar GM (2010) Role of late maternal thyroid hormones in cerebral cortex development: an experimental model for human prematurity. Cerebral Cortex, 20(6), pp. 1462 - 1475 . ISSN: 1047-3211

Azkona G, Amador-Arjona A, Obradors-Tarragó C, Varea E, Arqué G, Pinacho R, Fillat C, de la Luna S, Estivill X, Dierssen M. (2010) Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2. Genes Brain and Behavior, 9(2), pp. 160 - 172 . ISSN: 1601-1848

Castro JE, Varea E, Márquez C, Cordero MI, Poirier G, Sandi C (2010) Role of the amygdala in antidepressant effects on hippocampal cell proliferation and survival and on depression-like behavior in the rat. Plos One, 5(1), pp. 8618 - 8629 . ISSN: 1932-6203

Nacher J, Guirado R, Varea E, Alonso-Llosa G, Röckle I, Hildebrandt H (2010) Divergent impact of the polysialyltransferases ST8SiaII and ST8SiaIV on polysialic acid expression in immature neurons and interneurons of the adult cerebral cortex. Neuroscience, 167(3), pp. 825 - 837 . ISSN: 0306-4522

Gracia-Llanes FJ, Blasco-Ibáñez JM, Nacher J, Varea E, Liberia T, Martínez P, Martínez-Guijarro FJ, Crespo C (2010) Synaptic connectivity of serotonergic axons in the olfactory glomeruli of the rat olfactory bulb. Neuroscience, 169, pp. 770 - 780 . ISSN: 0306-4522

Castillo-Gómez E, Gómez-Climent MA, Varea E, Guirado R, Blasco-Ibáñez JM, Crespo C, Martínez-Guijarro FJ, Nácher J. (2008) Dopamine acting through D2 receptors modulates the expression of PSA-NCAM, a molecule related to neuronal structural plasticity, in the medial prefrontal cortex of adult rats. Experimental Neurology, 214(1), pp. 97 - 111 . ISSN: 0014-4886

Gomez-Climent MA; Guirado R; Varea E; Nàcher J. (2010) 'Arrested development'. Immature, but not recently generated, neurons in the adult brain. Archives Italiennes de Biologie, 148(2), pp. 159 - 172 . ISSN: 0003-9829

Gómez-Climent MA, Guirado R, Castillo-Gómez E, Varea E, Gutièrrez-Mecinas, M, Gilabert-Juan J, Sánchez-Mataredona D, Hernández S, Blasco-Ibáñez JM, Crespo C, Rutishauser U, Schachner M, Nacher J (2011) The polysialylated form of the neural cell adhesion molecule (PSA-NCAM) is expressed in mature cortical interneuons and influences their structure and connectivity. Cerebral Cortex, 21(5), pp. 1028 - 1041 . ISSN: 1047-3211

Castillo-Gómez E; Varea E; Blasco-Ibáñez JM; Crespo C; Nacher J. (2011) Polysialic Acid is required for dopamine d2 receptor-mediated plasticity involving inhibitory circuits of the rat medial prefrontal cortex. Plos One, 6(12), p. e29516 . ISSN: 1932-6203

Gracia-Llanes FJ, Crespo C,Blasco-Ibáñez JM, Nacher J, Varea E, Rovira-Esteban L, Martínez-Guijarro FJ, (2010) GABAergic basal forebrain afferents innervate selectively GABAergic targets in the main olfactory bulb. Neuroscience, 170, pp. 913 - 922 . ISSN: 0306-4522

Conboy, L., Varea, E., Castro, J.E., Sakouhi-Ouertatani, H., Calandra, T., Lashuel, H.A., Sandi, C. (2011) Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and mememory related behaviors. Molecular Psychiatry, 16(5), pp. 533 - 547 . ISSN: 1359-4184

Varea E; Guirado R; Gilabert-Juan J; Martí U; Castillo-Gomez E; Blasco-Ibáñez JM; Crespo C; Nacher J. (2012) Expression of PSA-NCAM and synaptic proteins in the amygdala of psychiatric disorder patients. Journal of Psychiatric Research, 46, pp. 189 - 197 . ISSN: 0022-3956

Guirado R; Sanchez-Matarredona D; Varea E; Crespo C; Blasco-Ibanez JM; Nacher J. (2012) Chronic fluoxetine treatment in middle-aged rats induces changes in the expression of plasticity-related molecules and in neurogenesis. Bmc Neuroscience, 13, p. 5 . ISSN: 1471-2202

Varea E, Belles M, Vidueira S, Blasco-Ibáñez JM, Crespo C, Pastorand AM, Nacher J (2011) PSA-NCAM is Expressed in Immature, but not Recently Generated, Neurons in the Adult Cat Cerebral Cortex Layer II. Frontiers In Neuroscience, 5(17), pp. 1 - 9 . ISSN: 1662-453X

Castro E; Diessler S; Varea E; Marquez C; Larsen MH; Cordero MI, Sandi C (2012) Personality traits in rats predict vulnerability and resilience to developing stress-induced depression-like behaviors, HPA axis hyper-reactivity and brain changes in pERK1/2 activity. Psychoneuroendocrinology, 37(8), pp. 1209 - 1223 . ISSN: 0306-4530

Hernández S; Gilabert-Juan J; Blasco-Ibáñez JM; Crespo C; Nácher J; Varea E. (2012) Altered expression of neuropeptides in the primary somatosensory cortex of the Down syndrome model Ts65Dn. Neuropeptides, 46, pp. 29 - 37 . ISSN: 0143-4179

Liberia T; Blasco-Ibáñez JM; Nácher J; Varea E; Zwafink V; Crespo C. (2012) Characterization of a Population of tyrosine hydroxylase-containing interneurons in the external plexiform layer of the rat olfactory bulb. Neuroscience, 217, pp. 140 - 153 . ISSN: 0306-4522

Liberia T; Blasco-Ibáñez JM; Nácher J; Varea E; Lanciego JL; Crespo C. (2012) Two Types of periglomerular cells in the olfactory bulb of the macaque monkey (Macaca fascicularis). Brain Structure & Function, 218(4), pp. 873 - 887 . ISSN: 1863-2653

Gilabert-Juan J, Varea E, Guirado R, Blasco-Ibáñez JM, Crespo C, Nácher J. (2012) Alterations in the expression of PSA-NCAM and synaptic proteins in the dorsolateral prefrontal cortex of psychiatric disorder patients. Neuroscience Letters. ISSN: 0304-3940

Martí-Mengual U, Varea E, Crespo C, Blasco-Ibáñez JM, Nacher J. (2013) Cells expressing markers of immature neurons in the amygdala of adult humans. European Journal of Neuroscience, 37(1), pp. 10 - 22 . ISSN: 0953-816X

Guirado R; Perez-Rando M; Sanchez-Matarredona D; Castillo-Gómez E; Liberia T; Rovira-Esteban L; Varea E; Crespo C; Blasco-Ibáñez JM; Nacher J. (2014) The Dendritic Spines of Interneurons Are Dynamic Structures Influenced by PSA-NCAM Expression. Cerebral Cortex, 24(11), pp. 3014 - 3024 . ISSN: 1047-3211

Liberia T; Blasco-Ibáñez JM; Nácher J; Varea E; Lanciego JL; Crespo C. (2013) Two Types of periglomerular cells in the olfactory bulb of the macaque monkey (Macaca fascicularis). Brain Structure & Function, 218(4), pp. 873 - 887 . ISSN: 1863-2653

Crespo C; Liberia T; Blasco-Ibañez JM; Nácher J; Varea E. (2013) The Circuits of the olfactory bulb. The exception as a rule. Anatomical Record-Advances In Integrative Anatomy And Evolutionary Biology, 296, pp. 1401 - 1412 . ISSN: 1932-8486

Ballestín R; Blasco-Ibáñez JM; Crespo C; Nacher J; López-Hidalgo R; Gilabert-Juan J; Moltó D; Varea E. (2014) Astrocytes of the murine model for Down Syndrome Ts65Dn display reduced intracellular ionic zinc. Neurochemistry International, 75, pp. 48 - 53 . ISSN: 0197-0186

Crespo C; Liberia T; Blasco-Ibáñez JM; Nácher J; Varea E. (2013) The Circuits of the Olfactory Bulb. The Exception as a Rule. Anatomical Record-Advances In Integrative Anatomy And Evolutionary Biology, En prensa . ISSN: 1932-8486

Guirado R; Perez-Rando M; Sanchez-Matarredona D; Castillo-Gómez E; Liberia T; Rovira-Esteban L; Varea E; Crespo C; Blasco-Ibáñez JM; Nacher J. (2014) The Dendritic Spines of Interneurons Are Dynamic Structures Influenced by PSA-NCAM Expression. Cerebral Cortex, 24, pp. 3014 - 3024 . ISSN: 1047-3211

Liberia T; Blasco-Ibáñez JM; Nácher J; Varea E; Lanciego JL; Crespo C. (2015) Synaptic connectivity of the cholinergic axons in the olfactory bulb of the cynomolgus monkey. Frontiers In Neuroanatomy. ISSN: 1662-5129

Hernández-González S; Ballestín R; López-Hidalgo R; Gilabert-Juan J; Blasco-Ibáñez JM; Crespo C; Nácher J; Varea E. (2015) Altered distribution of hippocampal interneurons in the murine Down Syndrome model Ts65Dn. Neurochemical Research, 40(1), pp. 151 - 164 . ISSN: 0364-3190

Castillo-Gómez E; Varea E; Blasco-Ibáñez JM; Crespo C; Nacher J. (2016) Effects of Chronic Dopamine D2R Agonist Treatment and Polysialic Acid Depletion on Dendritic Spine Density and Excitatory Neurotransmission in the mPFC of Adult Rats. Neural Plasticity, 2016, p. 1615363 . ISSN: 0792-8483

López-Hidalgo R; Ballestín R; Vega J; Blasco-Ibáñez JM; Crespo C; Gilabert-Juan J; Nácher J; Varea E. (2016) Hypocellularity in the Murine Model for Down Syndrome Ts65Dn Is Not Affected by Adult Neurogenesis. Frontiers In Neuroscience. ISSN: 1662-453X

Mulet M; Blasco-Ibañez JM; Crespo C; Nacher J; Varea E (2017) Early increased density of COX-2 immunoreactive neurons in Down Syndrome. Folia Neuropathologica, 55(2), pp. 1 - 7 . ISSN: 1641-4640

Villarroya O; Ballestín R; López-Hidalgo R; Mulet M; Blasco-Ibánez JM; Crespo C; Nácher J; Gilabert-Juan J; Varea E (2018) Morphological alterations in the hippocampus of the Ts65Dn mouse model for Down Syndrome correlate with structural plasticity markers. Histology and Histopathology, 33(1), pp. 101 - 115 . ISSN: 0213-3911

Perez-Rando M; Castillo-Gómez E; Guirado R; Blasco-Ibañez JM; Crespo C; Varea E; Nacher J (2017) NMDA Receptors Regulate the Structural Plasticity of Spines and Axonal Boutons in Hippocampal Interneurons. Frontiers In Cellular Neuroscience, 11(166) . ISSN: 1662-5102

Crespo C; Liberia T; Blasco-Ibáñez JM; Nácher J; Varea E. (2019) Cranial Pair I: The Olfactory Nerve. The Anatomical Record, 302(3), pp. 405 - 427 . ISSN: 0003-276X

Alcaide J; Guirado; Crespo C; Blasco-Ibáñez JM; Varea E; Sanjuan J; Nacher J. (2019) Alterations of perineuronal nets in the dorsolateral prefrontal cortex of neuropsychiatric patients. International Journal Of Bipolar Disorders, 7(1), p. 24 . ISSN: 2194-7511

Rovira-Esteban L; Hájos N; Nagy GA; Crespo C; Nacher J; Varea E; Blasco-Ibáñez JM. (2020) Semilunar granule cells are the primary source of the perisomatic excitatory innervation onto parvalbumin-expressing interneurons in the dentate gyrus. Eneuro, ENEURO.0323-19. . ISSN: 2373-2822

Carbonell J; Blasco-Ibáñez JM; Crespo C; Nácher J; Varea E (2020) Piriform cortex alterations in the Ts65Dn model for down syndrome. Brain Research. ISSN: 0006-8993

Pinto B; Morelli G; Rastogi M; Savardi A; Fumagalli A; Petretto A; Bartolucci M; Varea E; Catelani T; Contestabile A; Perlini LE; Cancedda L (2020) Rescuing over-activated microglia restores cognitive performance in juvenile animals of the Dp(16) mouse model of Down Syndrome. Neuron, 108(5), pp. 887 - 904 . ISSN: 0896-6273

Mulet M; Blasco-Ibáñez JM; Kirstein M; Crespo C; Nacher J; Varea E. (2020) Phenotypic characterization of MCP-1 expressing neurons in the rat cerebral cortex. Journal of Chemical Neuroanatomy, 106, p. 101785 . ISSN: 0891-0618

Bellés M; Carbonell J; Blasco-Ibáñez JM; Crespo C; Nácher J; Varea E (2019) Alterations in reelin and reelin receptors in Down syndrome. Neuroreport. ISSN: 0959-4965

Kirstein M; Cambrils A; Segarra A; Melero A; Varea E (2022) Cholinergic Senescence in the Ts65Dn Mouse Model for Down Syndrome. Neurochemical Research, 47(10), pp. 3076 - 3092 . ISSN: 0364-3190

Coviello S; Gramuntell Y; Klimczak P; Varea E; Blasco-Ibañez JM; Crespo C; Gutierrez A; Nacher J. (2022) Phenotype and Distribution of Immature Neurons in the Human Cerebral Cortex Layer II. Frontiers In Neuroanatomy, 16, p. 851432 . ISSN: 1662-5129

Olivas-Cano I; Rodriguez-Andreu JM; Blasco-Ibañez JM; Crespo C; Nácher J; Varea E (2023) Fluoxetine increased adult neurogenesis is mediated by 5-HT3 receptor. Neuroscience Letters, 795, p. 137027 . ISSN: 0304-3940

López-Hidalgo, R.; Ballestín, R.; Lorenzo, L.; Sánchez-Martí, S.; Blasco-Ibánez, J.M.; Crespo, C.; Nacher, J.; Varea, E. (2024) Early chronic fasudil treatment rescues hippocampal alterations in the Ts65Dn model for down syndrome. Neurochemistry International, 174(March 2024), p. 105679 . ISSN: 0197-0186

Pastor-Alonso O; Durá I; Bernardo-Castro S; Varea E; Muro-García T; Martín-Suárez S; Encinas-Pérez JM; Pineda JR (2024) HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures. Life Science Alliance, 7(9), pp. e202201840-1 - 20 . ISSN: 2575-1077

Klimczak P; Alcaide J; Gramuntell Y; Castillo-Gómez E; Varea E; Perez-Rando M; Nacher J (2024) Long-term effects of a double hit murine model for schizophrenia on parvalbumin expressing cells and plasticity-related molecules in the thalamic reticular nucleus and the habenula. Translational Psychiatry, 14(Art. 450) . ISSN: 2158-3188

Recatalá M; Hidalgo P; Nàcher J; Blasco-Ibáñez JM; Crespo C; Varea E (2025) Ondansetron blocks fluoxetine effects in immature neurons in the adult rat piriform cortex layer II. Neuroscience Letters, 847, pp. 138099-1 - 7 . ISSN: 0304-3940

36828 - Cell Biology - Degree in Biology
36860 - Microscopic Techniques - Degree in Biology

Fitxa persona