ANTONIO JOSE GUILLOT GARCIA
PDI-Ajudant Doctor/A
PDI-Ajudant Doctor/A
Knowledge area: PHARMACY AND PHARMACEUTICAL TECHNOLOGY
Department: Pharmacy, Pharmaceutical Technology and Parasitology
Department: Pharmacy, Pharmaceutical Technology and Parasitology
Academic training
- Farmacia. Universitat de Valencia. (Diploma / Degree / Activities).
- Advanced Systems for Skin Delivery of Cyanocobalamin: A Model Molecule for > 1kDa Drugs. Universidad de Valencia. 07/10/2022 (Ph.D.).
- Investigación y desarrollo de medicamentos. Universitat de Valencia. (Official Master).
Journal Publications
- Lia Carolina Oliveira dos Santos; Carlonie Magnani Spagnol; Antonio Guillot; Ana Melero; Antonio Correa (2019) Caffeic Acid skin absorption: delivery of microparticles to hair follicles. Saudi Pharmaceutical Journal, 27, pp. 791 - 797 . ISSN: 1319-0164
- Christfort JF, Guillot AJ, Melero A, Thamdrup LHE, Garrigues TM, Boisen A, Zór K, Nielsen LH. (2020) Cubic Microcontainers Improve In Situ Colonic Mucoadhesion and Absorption of Amoxicillin in Rats. Pharmaceutics, 12(355) . ISSN: 1999-4923
- Carreras, J.J.; Tapia-Ramirez, W.E.; Sala, A.; Guillot, A.J.; Garrigues, T.M.; Melero, A. (2020) Ultraflexible lipid vesicles allow topical absorption of cyclosporin A. Drug Delivery And Translational Research, 10, pp. 486 - 497 . ISSN: 2190-393X
- Antonio José Guillot; Ana Sara Cordeiro; Ryan F. Donnelly; M. Carmen Montesinos; Teresa M. Garrigues and Ana Melero. (2020) Microneedle-Based Delivery: An Overview of Current Applications and Trends. Pharmaceutics, 12(6), pp. 569-1 - 27 . ISSN: 1999-4923
- Melero, A.; Guillot, A.J; Carneiro, C.; Nuñez-Sanchez, H.; Rodríguez-Martí, L.; Chiari-Andréo, B.G.; Marto, J.; Ribeiro, H.; Garrigues, T.; Isaac, V. (2020) Caffeine analysis and extraction from a topical cream intended for UV-skin protection. Journal of Dispersion Science and Technology, 43(2), pp. 157 - 163 . ISSN: 0193-2691
- Guillot, A.J.; Petalas, D.; Skondra, P.; Rico, H.; Garrigues, T.M.; Melero, A. (2021) Ciprofloxacin self-dissolvable Soluplus based polymeric films: a novel proposal to improve the management of eye infections. Drug Delivery And Translational Research, 11, pp. 608 - 625 . ISSN: 2190-393X
- Guillot, A.J.; Jornet-Mollá, E; Landsberg, N; Milián-Guimerá. C; Montesinos, M.C.; Garrigues, T.M.; Melero, A. (2021) Cyanocobalamin ultraflexible lipid vesicles: Characterization and in vitro evaluation of drug-skin depth profiles. Pharmaceutics, 13(3), p. 418 . ISSN: 1999-4923
- Vicente Mirabet; Daniel García; Amparo Roca; Arnold R Quiroz; Joan Antón; Miguel Rodríguez-Cadarso; Dolores Ocete; Lucas Aranda; Ana Melero; Antonio J Guillot; Nuria Yagüe; Isabel Guillén; Carlos Botella. (2021) Cranioplasty with Autologous Bone Flaps Cryopreserved with Dimethylsulphoxide: Does Tissue Processing Matter. World Neurosurgery, 149, pp. 582 - 591 . ISSN: 1878-8750
- V. Mirabet; M. Arrébola; J. Briones; M. P. Bosch; M. D. Ocete; A. Melero; S. Mirabet; L. Aranda; A. J. Guillot; L. R. Larrea; C. Escobedo-Lucea; J. Pemán (2021) Microbiological assessment of arterial allografts processed in a tissue bank. Cell And Tissue Banking, 22, pp. 539 - 549 . ISSN: 1389-9333
- Bruna G. Chiari-Andréo; Joana Marto; Andreia Ascenso; Carlos Carneiro; Laura Rodríguez; Antonio José Guillot; Teresa M Garrigues; Helena M Ribeiro; Ana Melero; Vera Isaac (2021) The Impact of Titanium Dioxide Type Combined with Coffee Oil Obtained from Coffee Industry Waste on Sunscreen Product Performance. Dermato. ISSN: 2673-6179
- Rafaela Santos de Oliveira, Stephani Silva Fantaus, Antonio José Guillot, Ana Melero, Ruy Carlos Ruver Beck (2021) 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery. Pharmaceutics, 13(11), pp. 1946-1 - 39 . ISSN: 1999-4923
- Antonio José Guillot, Pablo Merino-Gutiérrez, Andrea Bocchino, Conor O'Mahony, Rosa Maria Giner, Maria Carmen Recio, Teresa Maria Garrigues, Ana Melero (2022) Exploration of Microneedle-assisted skin delivery of cyanocobalamin formulated in ultraflexible lipid vesicles. European Journal of Pharmaceutics and Biopharmaceutics, 177, pp. 184 - 198 . ISSN: 0939-6411
- Leonardo Delello Di Filippo,Jonatas Lobato Duarte,Cesar Augusto Roque-Borda,Fernando Rogério Pavan, Andreia Bagliotti Meneguin, Marlus Chorilli,Ana Melero, Antonio José Guillot,Caroline Magnani Spagnol, Marcos Antônio Correa (2022) In Vitro Skin Co-Delivery and Antibacterial Properties of Chitosan-Based Microparticles Containing Ascorbic Acid and Nicotinamide. Life-Basel, 12(1049) . ISSN: 2075-1729
- Andressa MariaPironi, AnaMelero, Josimar O.Eloy, Antonio JoséGuillot, KaioPini Santos, MarlusChorilli (2022) Solid dipersions included in poloxamer hydrogels have favorable rheological properties for topical application and enhance the in vivo antiinflammatory effect of ursolic acid. Journal Of Drug Delivery Science And Technology, 74, pp. 103602-1 - 12 . ISSN: 1773-2247
- Guillot AJ, Martínez-Navarrete M; Garrigues TM; Melero A (2023) Skin drug delivery using lipid vesicles: A starting guideline for their development. Journal of Controlled Release, 355, pp. 624 - 654 . ISSN: 0168-3659
- Guillot AJ; Martínez-Navarrete M; Zinchuk-Mironova V; Melero A (2023) Microneedle-assisted transdermal delivery of nanoparticles: Recent insights and prospects. Wiley Interdisciplinary Reviews-Nanomedicine And Nanobiotechnology, e1884, pp. 2 - 30 . ISSN: 1939-5116
- S. Demartis; G. Rassu; V. Mazzarello; E. Larrañeta; A. Hutton; R.F. Donnelly; A. Dalpiaz; M. Roldo; A.J. Guillot; A. Melero; P. Giunchedi; E. Gavini (2023) Delivering hydrosoluble compounds through the skin: what are the chances?. International Journal of Pharmaceutics, 646(123457) . ISSN: 0378-5173
- Miquel Martínez-Navarrete; Antonio José Guillot; Maria C. Lobita; María Carmen Recio; Rosa Giner; Juan Aparicio-Blanco; María Carmen Montesinos; Hélder A. Santos; Ana Melero (2024) Cyclosporin A-loaded dissolving microneedles for dermatitis therapy: Development, characterisation and efficacy in a delayed-type hypersensitivity in vivo model. Drug Delivery And Translational Research. ISSN: 2190-393X
- Miquel Martínez-Navarrete; Alexandre Pérez-López; Antonio José Guillot; Ana Sara Cordeiro; Ana Melero; Juan Aparicio-Blanco (2024) Latest advances in glucose-responsive microneedle-based systems for transdermal insulin delivery. International Journal of Biological Macromolecules. ISSN: 0141-8130
- Duarte RS Almeida; João Ferreira Gil; Antonio José Guillot, Jiachen Li; Ricardo JB Pinto; Hélder A Santos; Gil Gonçalves (2024) Advances in Microfluidic-Based Core@Shell Nanoparticles Fabrication for Cancer Applications. Advanced Healthcare Materials, 13(23), pp. 1 - 26 . ISSN: 2192-2640
- Antonio José Guillot; Miquel Martínez-Navarrete; Rosa Maria Giner; Maria Carmen Recio; Helder A. Santos; Ana Sara Cordeiro; Ana Melero (2024) Cyanocobalamin-loaded dissolving microneedles diminish skin inflammation in vivo. Journal of Controlled Release, 375, pp. 537 - 551 . ISSN: 0168-3659
- Paula Bucci; Miquel Martínez-Navarrete; Francisco J. Marti-Quijal; Antonio José Guillot; Francisco J. Barba; Emilia Ferrer; Danilo Cantero; Raúl Muñoz; Ana Melero (2024) In vivo reduction of skin inflammation using ferulic acid-loaded lipid vesicles derived from Brewer¿s spent grain. International Journal of Pharmaceutics, 666, pp. 124764-1 - 12 . ISSN: 0378-5173
- Miquel Martínez-Navarrete; Mafalda Correia; J.Alejandro Bernabeu-Martínez; Ana Cláudia Paiva-Santos; Ana Borrego-Sánchez; Antonio José Guillot (2025) Enhanced ex vivo skin retention of bicalutamide using a nano-in-micro composite: Drug-loaded lipid vesicles in a dissolving microarray patch. European Journal of Pharmaceutics and Biopharmaceutics, 212(114728), pp. 1 - 12 . ISSN: 0939-6411
- Antonio José Guillot; Ana Melero (2025) (Re)evolution in nanoparticles-loaded microneedle delivery systems: are we getting closer to a clinical translation?. Nanomedicine, 20(10), pp. 1195 - 1207 . ISSN: 1743-5889
- Andressa Tardim Cruz; Leonardo Delello Di Filippo; Jonatas Lobato Duarte; Antonio José Guillot; Alberto Pérez-García; Ana Melero andMarlus Chorilli (2025) Solid Lipid Nanoparticles for Skin Delivery of Trans-Resveratrol: Impact of Preparation Methods on Formulation Stability. Cosmetics, 12(7), pp. 1 - 10 . ISSN: 2079-9284
- Renan Stein; Miquel Martínez-Navarrete; Ana Paula Leão; Ana Melero; Silvio Buchner; Edilson Valmir Benvenutti; Monique Deon; Antonio José Guillot; Ruy Carlos Ruver Beck (2025) Curcumin and resveratrol loaded in nanostructured mesoporous silica as a promising delivery system in Inflammatory Bowel Disease. Journal Of Drug Delivery Science And Technology, 112(107262), pp. 1 - 16 . ISSN: 1773-2247
- Matilde R. Rodrigues; Patrícia C. Pires; Ana Melero; Antonio José Guillot; Ana Borrego-Sánchez; Alina Sesarman; Manuela Banciu; Francisco Veiga; Ana Cláudia Paiva-Santos (2025) Anti-inflammatory drug repurposing in skin diseases: ketoprofen-loaded nanoemulsion development and characterization for topical administration. European Journal of Pharmacology, 1004, p. 177992 . ISSN: 0014-2999
- Miquel Martínez-Navarrete; María Carmen Recio; Rosa María Giner; Francisco J. Martí-Quijal; Antonio José Guillot; Ana Melero (2026) Ultraflexible lipid vesicles loaded with cyanocobalamin or cyclosporin A downregulate acute and chronic immuno-inflammatory skin states. Journal of Controlled Release, 389(114461) . ISSN: 0168-3659
- Antonio José Guillot; Miquel Martínez-Navarrete; Jose Alejandro Bernabeu-Martínez; Miguel Ángel Rubio-López; Ana Melero (2026) Dissolving Microneedle Array Patches Manufactured By Solvent Casting Technique and Essential Characterization of Microneedle-Based Biomedical Devices. Jove-Journal Of Visualized Experiments, 227, p. e69923 . ISSN: 1940-087X
- Anitta Lutta; Miquel Martínez-Navarrete; Matteo Tollemeto; Amalie Kjær Andresen; Gabriel Kristian Pedersen; Antonio José Guillot; Zhongyang Zhang; Holger Grohganz; Ana Melero; Signe Tandrup Schmidt; Line Hagner Nielsen (2026) The Role of Pectin in Optimizing Cationic Liposomes for Oral Delivery. ACS Applied Bio Materials, 9(6), pp. 2815 - 2826 . ISSN: 2576-6422
- Isadora de Souza Lopes; Bruno Dufau Mattos; Antonio José Guillot; Zhangmin Wan; Yi Lu; Luiz Henrique Fasolin; Hélder A. Santos; Orlando J. Rojas; Carolina Siqueira Franco Picone (2026) Co-precipitation of quercetin and lignin: unveiling phenolic fruit-derived extracts encapsulation. Chemical Engineering Journal, 537, pp. 176172-1 - 12 . ISSN: 1385-8947
Other publications
- Melero A; Guillot AJ; Garrigues TM (2022). ¿Un inofensivo tatuaje o la eterna lucha de nuesto sistema inmune? Lo que debes saber sobre medicamentos y salud . (pp. 369 - 376) .
- Melero A; Guillot AJ; Garrigues TM (2022). ¿Vapear es más sano que fumar? Lo que debes saber sobre medicamentos y salud . (pp. 377 - 385) .
- Antonio José Guillot; Miquel Martínez-Navarrete; José Alejandro Bernabeu-Martínez; Ana Sara Cordeiro; Ana Melero (2025). Microneedles: Fabrication, Characterization and Translational Potential Microneedles (MNs)-Based Technology . (pp. 1 - 41) .
Stays abroad in Research Centers
- Leicester. UNITED KINGDOM, 2022. Liposome-loaded microneedles for topical drug delivery. **Doctorand.
Projects
- Desarrollo y caracterización de una crema radioprotectora para la prevención de quemaduras radioinducidas (BIOMED ). 2018 - 2019. Universitat de València. Instituto de Investigación Sanitaria - Fundación para la Investigación Hospital La Fe (IIS-La Fe). PI: Ana Melero Zaera y Natividad Sebastià Fabregat.
- Microagujas solubles cargadas con Colistina para el tratamiento local de infecciones bacterianas cutáneas (COL@DMAPs4SKIN) (). 2025 - 2026. Conselleria d'Educació, Cultura i Universitats. . PI: Antonio José Guillot García.
- Optimización de la administración tópica de fármacos mediante herramientas no invasivas (TopDDOp) (). 2021 - 2024. Ministerio de Ciencia e Innovación. Agencia Estatal de Investigación (AEI). PI: Ana Melero.
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