JOSE GARCIA MARTINEZ
PDI-Titular d'Universitat
Director/a de Departament
PDI-Titular d'Universitat
Director/a de Departament
Área de conocimiento: GENETICA
Departamento: Genética
Departamento: Genética
Edificio B de Biología, 6ª planta
Despacho 2.12.P6.038
96 3543402
43402 (I)
96 3543402
43402 (I)
Asignaturas impartidas y modalidades docentes
Formación académica
- Llicenciat amb Grau amb Premi Extraordinari. Facultat de Biología. 02/04/1993 (Diplomatura / Licenciatura / Grado).
- Doctor en Ciencies Biològiques. Dept. de Genètica, Universitat de València. 18/09/1996 (Doctorado).
Publicaciones en revistas
- García-Martínez, J; Barrio, E; Raga, J.A. and Latorre, A (1995) Mitochondrial DNA variability of striped dolphin (Stenella coeruleoalba) in the Mediterranean Spanish waters. Marine Mammal Science, 11(2), pp. 183 - 199 . ISSN: 0824-0469
- Martínez-Izquierdo, J.A; García-Martínez, J. and Vicient, C.M. (1997) What makes Grande1 retrotransposon different?. Genetica, 100, pp. 15 - 28 . ISSN: 0016-6707
- García-Martínez, J; Castro, J.A; Ramón, M; Latorre, A. and Moya, A. (1998) Mitochondrial DNA haplotype frequencies in natural and experimental populations of Drosophila subobscura. Genetics, 149, pp. 1377 - 1382 . ISSN: 0016-6731
- García-Martínez, J; Raga, J.A. and Latorre, A (1999) Genetic differentiation in the striped dolphin Stenella coeruleoalba from European waters according to mitochondrial DNA (mtDNA) restriction analysis. Molecular Ecology, 8(6), pp. 1069 - 1073 . ISSN: 0962-1083
- Pérez-Ortín, J.E.; García-Martínez, J. and Alberola T. M. (2002) DNA chips for yeast biotechnology. The case of wine yeasts. Journal of Biotechnology, 98, pp. 227 - 241 . ISSN: 0168-1656
- Carro, D.; García-Martínez, J; Pérez-Ortín, J.E. y Piña, B. (2003) Structural characterization of chromosome I size variants from a natural yeast strain. Yeast, 20, pp. 171 - 180 . ISSN: 1097-0061
- García-Martínez, J. and Martínez-Izquierdo, J.A. (2003) Study on the evolution of the Grande retrotransposon in the Zea genus. Molecular Biology and Evolution, 20(5), pp. 831 - 841 . ISSN: 0737-4038
- Alberola, T. M., García-Martínez, J., Antúnez, O., Viladevall, L., Barceló, A., Ariño, J. y Pérez-Ortín, J.E. (2004) A new set of DNA macrochips for the yeast Saccharomyces cerevisiae: features and uses. International Microbiology, 7(3), pp. 199 - 206 . ISSN: 1139-6709
- Pérez-Ortín, J.E. y García-Martínez, J. (2004) Evaluation of transcription rates at the genomic level. Bioforum Europe, 8(5), pp. 46 - 48 . ISSN: 1611-597X
- Bellí, G.; Molina, M.M.; García Martínez, José; Pérez-Ortín, José Enrique; Herrero, Enrique (2004) Saccharomyces cerevisiae glutaredoxin 5-deficient cells subjected to constitutive oxidizing conditions are affected in the expression of specific sets of genes. Journal of Biological Chemistry, 279(13), pp. 12386 - 12395 . ISSN: 0021-9258
- Garcia Martinez, José; Aranda Fernández, Agustín; Pérez Ortín, José Enrique (2004) Genomic run-on evaluates transcription rates for all yeast genes and identifies gene regulatory mechanisms. Molecular Cell, 15(2), pp. 303 - 313 . ISSN: 1097-2765
- Güldener, U; Münsterkötter, M.; Kastenmüller, G; Strack1, N; van Helden, J.; Lemer, C.; Richelles, J.; Wodak, S.J.; García Martínez, José; Pérez Ortín, José E.; Michael, H.; Kaps, A.; Talla, E.; Dujon, B.; André, B.; Souciet, J.L.; De Montigny, J.; Bon, E.; Gaillardin, C. y Mewes, H.W (2005) CYGD: The Comprehensive Yeast Genome Database. Nucleic Acids Research, 33(suppl 1), pp. D364 - D368 . ISSN: 0305-1048
- Pelechano, Vicente José; García Martínez, José; Pérez Ortín, José Enrique (2006) A genomic study of the Inter-ORF distances in Saccharomyces cerevisiae. Yeast, 23, pp. 689 - 699 . ISSN: 1097-0061
- Castillo, L; Martínez, A.I; Garcerá, A; García-Martínez, J; Ruiz-Herrera, J; Valentín, E. and Sentandreu, R (2006) Genomic response programs of Candida albicans following protoplasting and regeneration. Fungal Genetics and Biology, 43, pp. 124 - 134 . ISSN: 1087-1845
- Mendes-Ferreira A.; Olmo Muñoz, Marcel·lí del; García Martínez José; Jiménez Martí Elena; Mendes-Faia A.; Pérez Ortín, José Enrique; Leão C. (2007) Transcriptional response of Saccharomyces cerevisiae to different nitrogen concentrations during alcoholic fermentation. Applied and Environmental Microbiology, 73(9), pp. 3049 - 3060 . ISSN: 0099-2240
- Rosaleny Peralvo, Lorena Estefanía; Ruiz García, Ana Belén; García Martínez, José; Pérez Ortín, José Enrique; Tordera Donderis, Vicente (2007) The Sas3p and Gcn5p histone acetyltransferases are recruited to similar genes. Genome biology, 8(6), p. R119 . ISSN: 1474-7596
- Mendes-Ferreira A.; Olmo Muñoz, Marcel·li del; García Martínez José; Jiménez Martí, Elena; Leão, C.; Mendes-Faia A, Pérez Ortín José E. (2007) Saccharomyces cerevisiae signature genes for predicting nitrogen deficiency during alcoholic fermentation. Applied and Environmental Microbiology, 73(16), pp. 5363 - 5369 . ISSN: 0099-2240
- García Martínez, José; González Candelas, Fernando; Pérez Ortín, José Enrique (2007) Common gene expression strategies revealed by genome-wide analysis in yeast. Genome biology, 8, p. R222 . ISSN: 1474-7596
- Molina-Navarro, M.M.; Castells-Roca, L.; Bellí, G.; García-Martínez, J.; Marín-Navarro, J.; Moreno, J. Pérez-Ortín, J.E. y Herrero, E. (2008) Comprehensive transcriptional analysis of the oxidative response in yeast. Journal of Biological Chemistry, 283, pp. 17908 - 17918 . ISSN: 0021-9258
- Campo, S; Manrique, S; García-Martínez, J. and San Segundo, B (2008) Production of Cecropin A in transgenic rice plants has an impact on host gene expression. Plant Biotechnology Journal, 6, pp. 585 - 608 . ISSN: 1467-7644
- Belloch, Carmela; Pérez Torrado, Roberto; González, Sara S.; Pérez Ortín, José Enrique; García Martínez, José; Querol Simón, Amparo; Barrio Esparducer, Eladio (2009) Chimeric Genomes of Natural Hybrids of Saccharomyces cerevisiae and Saccharomyces kudriavzevii. Applied and Environmental Microbiology, 75(8), pp. 2534 - 2544 . ISSN: 0099-2240
- Pelechano García, Vicente José; Jimeno-González, Silvia; Rodríguez-Gil, Alfonso; García Martínez, José; Pérez Ortín, José Enrique; Chávez, Sebastián (2009) Regulon-specific control of transcription elongation across the yeast genome. PLOS genetics, 5(8), p. e1000614 . ISSN: 1553-7390
- Bermúdez, Ignacio; García Martínez, José; Pérez Ortín, José Enrique; Roca, Joaquim (2010) A method for genome-wide analysis of DNA helical tension by means of psoralen-DNA photobinding. Nucleic Acids Research, 38(19), p. e182 . ISSN: 0305-1048
- Rodríguez-Gil, Alfonso; García Martínez, José; Pelechano García, Vicente José; Muñoz-Centeno, María de la Cruz; Geli, Vincent; Pérez Ortín, José Enrique; Chávez, Sebastián (2010) The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors. Nucleic Acids Research, 38(14), pp. 4651 - 4664 . ISSN: 0305-1048
- Castells-Roca, L.; García-Martínez, J.; Moreno Mariño, Joaquín; Herrero, E.; Bellí, G. y Pérez Ortín, José Enrique (2011) Heat shock response in yeast involver changes in both transcription rates and mRNA stabilities. Plos One, 6(2), p. e17272 . ISSN: 1932-6203
- García Martínez, José; Ayala Gallego, Guillermo; Pelechano García, Vicente José; Chávez, S.; Herrero, E.; Pérez Ortín, José Enrique (2012) The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast. Transcription, 3(1), pp. 39 - 44 . ISSN: 2154-1264
- Campos-Soriano, L; García-Martínez, J. and San Segundo, B. (2012) The arbuscular mycorrhizal symbiosis promotes systemic induction of regulatory defence-related genes in rice leaves and confers resistance to pathogen infection. Molecular Plant Pathology, 13(6), pp. 579 - 592 . ISSN: 1464-6722
- Nikolaou, C.; Bermúdez, I.; Manichanh, C.; García-Martínez, José; Guigó, R.; Pérez-Ortín, José E.; Roca, J. (2013) Topoisomerase II regulates yeast genes with singular chromatin architectures. Nucleic Acids Research, 41(20), pp. 9243 - 9256 . ISSN: 0305-1048
- Barbosa C, García-Martínez J, Pérez-Ortín JE, Mendes-Ferreira A. (2015) Comparative Transcriptomic Analysis Reveals Similarities and Dissimilarities in Saccharomyces cerevisiae Wine Strains Response to Nitrogen Availability. Plos One, 10(4), p. e0122709 . ISSN: 1932-6203
- Canadell D, García-Martínez J, Alepuz P, Pérez-Ortín JE, Ariño J. (2015) Impact of high pH stress on yeast gene expression: A comprehensive analysis of mRNA turnover during stress responses. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms, 1849(6), pp. 653 - 664 . ISSN: 1874-9399
- García-Martínez, José; Delgado-Ramos, Lidia; Ayala, Guillermo; Pelechano, Vicent; Medina, Daniel A.; Carrasco, Fany; González, Ramón; Andrés-León, Eduardo; Steinmetz, Lars; Warringer, Jonas; Chávez, Sebastián; Pérez-Ortín, José E (2016) The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons. Nucleic Acids Research, 44, pp. 3643 - 3658 . ISSN: 0305-1048
- Garrido-Godino AI; García-López MC; García-Martínez J; Pelechano V; Medina DA; Pérez-Ortín JE; Navarro F. (2016) Rpb1 foot mutations demonstrate a major role of Rpb4 in mRNA stability during stress situations in yeast. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms, 1859(5), pp. 731 - 743 . ISSN: 1874-9399
- Sebastián Chávez; José García-Martínez;· Lidia Delgado-Ramos; José E. Pérez-Ortín (2016) The Importance of controlling mRNA turnover during cell proliferation. Current Genetics, 62(4), pp. 701 - 710 . ISSN: 0172-8083
- José García-Martínez; Kevin Troulé; Sebastián Chávez; José E. Pérez-Ortín (2016) Growth Rate controls mRNA turnover in steady and non-steady states. Rna Biology, 13(12), pp. 1175 - 1181 . ISSN: 1547-6286
- Adriana Mena, Daniel A. Medina, José García-Martínez, Victoria Begley, Abhyudai Singh, Sebastián Chávez, Mari C. Muñoz-Centeno, José E. Pérez-Ortín (2017) Asymmetric cell division requires specific mechanisms for adjusting global transcription. Nucleic Acids Research, 45(21), pp. 12401 - 12412 . ISSN: 0305-1048
- Varinia García‑Molinero, José García‑Martínez, Rohit Reja, Pedro Furió‑Tarí, Oreto Antúnez, Vinesh Vinayachandran, Ana Conesa, B. Franklin Pugh, José E. Pérez‑Ortín, Susana Rodríguez‑Navarro (2018) The SAGA/TREX‑2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally. Epigenetics & Chromatin, 11(13), pp. 1 - 12 . ISSN: 1756-8935
- Blasco-Moreno B; de Campos-Mata L; Böttcher R; García-Martínez J; Jungfleisch J; Nedialkova DD; Chattopadhyay S; Gas ME; Oliva B; Pérez-Ortín JE; Leidel SA; Choder M; Díez J (2019) The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins. Nature Communications, 10, p. 1298 . ISSN: 2041-1723
- Romero AM; Ramos-Alonso L; Montellá-Manuel S; García-Martínez J; de la Torre-Ruiz MÁ; Pérez-Ortín JE; Martínez-Pastor MT; Puig S (2019) A genome-wide transcriptional study reveals that iron deficiency inhibits the yeast TORC1 pathway. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms, 1862(9), p. 194414 . ISSN: 1874-9399
- Forés‐Martos, J.; Forte, A.; García‐Martínez, J; Pérez‐Ortín, J.E. (2021) A trans‐omics comparison reveals common gene expression strategies in four model organisms and exposes similarities and differences between them. Cells, 10(2), p. 334 . ISSN: 2073-4409
- Pérez-Ortín JE; Mena A; Barba-Aliaga M; Singh A; Chávez S; García-Martínez J. (2021) Cell volume homeostatically controls the rDNA repeat copy number and rRNA synthesis rate in yeast. Plos Genetics, 17(4), p. e1009520 . ISSN: 1553-7390
- García-Martínez J; Medina DA; Bellvis P; Sun M; Cramer P; Chávez S; Pérez-Ortín JE (2021) The total mRNA concentration buffering system in yeast is global rather than gene-specific. RNA-A Publication of the Rna Society, 27, pp. 1281 - 1290 . ISSN: 1355-8382
- José García-Martínez; María E Pérez-Martínez; José E Pérez-Ortín; Paula Alepuz (2021) Recruitment of Xrn1 to stress-induced genes allows efficient transcription by controlling RNA polymerase II backtracking. Rna Biology, 18(10), pp. 1458 - 1474 . ISSN: 1547-6286
- Romero, A.M.; García-Martínez, J.; Pérez-Ortín, J.E.; Martínez-Pastor, M.T.; Puig, S. (2022) Changes in mRNA stability play an important role in the adaptation of yeast cells to iron deprivation. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms, 1865, p. 194800 . ISSN: 1874-9399
- Vicente Arnau; Marina Barba-Aliaga; Gaurav Singh; Javier Ferri; José García-Martínez; José E. Pérez-Ortín (2022) A feedback mechanism controls rDNA copy number evolution in yeast independently of natural selection. Plos One, 17(9), p. e0272878 . ISSN: 1932-6203
- Shiladitya Chattopadhyay; Jose Garcia-Martinez; Gal Haimovich; Jonathan Fischer; Aya Khwaja; Oren Barkai; Silvia Gabriela Chuartzman; Maya Schuldiner; Ron Elran; Miriam I. Rosenberg; Shira Urim; Shubham Deshmukh; Katherine E. Bohnsack; Markus T. Bohnsack; Jose E. Perez-Ortin; Mordechai Choder (2022) RNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway. Nature Communications, 13(7184), pp. 1 - 17 . ISSN: 2041-1723
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