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Laboratorio de Fisiopatología de las Enfermedades Raras

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Publicaciones

A continuación una selección de publicaciones del grupo durante los últimos cinco años:

1. Seco-Cervera M, González-Rodríguez D, Ibáñez-Cabellos JS, Peiró-Chova L, Pallardó FV, García-Giménez JL. Small RNA-seq analysis of circulating miRNAs to identify phenotypic variability in Friedreich's ataxia patients. Sci Data. 2018 Mar 6;5:180021. doi: 10.1038/sdata.2018.21. PubMed PMID: 29509186; PubMed Central PMCID: PMC5839159.

2. García-Giménez JL, Rubio-Belmar PA, Peiró-Chova L, Hervás D, González-Rodríguez D, Ibañez-Cabellos JS, Bas-Hermida P, Mena-Mollá S, García-López EM, Pallardó FV, Bas T. Circulating miRNAs as diagnostic biomarkers for adolescent idiopathic scoliosis. Sci Rep. 2018 Feb 8;8(1):2646. doi: 10.1038/s41598-018-21146-x. PubMed PMID: 29422531; PubMed Central PMCID: PMC5805715.

3. García-Giménez JL, Seco-Cervera M, Tollefsbol TO, Romá-Mateo C, Peiró-Chova L, Lapunzina P, Pallardó FV. Epigenetic biomarkers: Current strategies and future challenges for their use in the clinical laboratory. Crit Rev Clin Lab Sci. 2017 Nov - Dec;54(7-8):529-550. doi: 10.1080/10408363.2017.1410520. Epub 2017 Dec 11. Review. PubMed PMID: 29226748.

4. Ibáñez-Cabellos JS, Pérez-Machado G, Seco-Cervera M, Berenguer-Pascual E, García-Giménez JL, Pallardó FV. Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. Redox Biol. 2018 Apr;14:398-408. doi: 10.1016/j.redox.2017.10.004. Epub 2017 Oct 7. PubMed PMID: 29055871; PubMed Central PMCID: PMC5650655.

5. Mollá B, Muñoz-Lasso DC, Riveiro F, Bolinches-Amorós A, Pallardó FV, Fernandez-Vilata A, de la Iglesia-Vaya M, Palau F, Gonzalez-Cabo P. Reversible Axonal Dystrophy by Calcium Modulation in Frataxin-Deficient Sensory Neurons of YG8R Mice. Front Mol Neurosci. 2017 Aug 30;10:264. doi: 10.3389/fnmol.2017.00264. eCollection 2017. PubMed PMID: 28912677; PubMed Central PMCID: PMC5583981.

6. García-Giménez JL, Romá-Mateo C, Carbonell N, Palacios L, Peiró-Chova L, García-López E, García-Simón M, Lahuerta R, Gimenez-Garzó C, Berenguer-Pascual E, Mora MI, Valero ML, Alpízar A, Corrales FJ, Blanquer J, Pallardó FV. A new mass spectrometry-based method for the quantification of histones in plasma from septic shock patients. Sci Rep. 2017 Sep 6;7(1):10643. doi: 10.1038/s41598-017-10830-z. PubMed PMID: 28878320; PubMed Central PMCID: PMC5587716.

7. García-Giménez JL, Romá-Mateo C, Pérez-Machado G, Peiró-Chova L, Pallardó FV. Role of glutathione in the regulation of epigenetic mechanisms in disease. Free Radic Biol Med. 2017 Nov;112:36-48. doi: 10.1016/j.freeradbiomed.2017.07.008. Epub 2017 Jul 10. Review. PubMed PMID: 28705657.

8. Seco-Cervera M, González-Rodríguez D, Ibáñez-Cabellos JS, Peiró-Chova L, González-Cabo P, García-López E, Vílchez JJ, Sanz-Gallego I, Pallardó FV, García-Giménez JL. Circulating miR-323-3p is a biomarker for cardiomyopathy and an indicator of phenotypic variability in Friedreich's ataxia patients. Sci Rep. 2017 Jul 12;7(1):5237. doi: 10.1038/s41598-017-04996-9. PubMed PMID: 28701783; PubMed Central PMCID: PMC5507909.

9. Romá-Mateo C, Aguado C, García-Giménez JL, Ibáñez-Cabellos JS, Seco-Cervera M, Pallardó FV, Knecht E, Sanz P. Increased oxidative stress and impaired antioxidant response in Lafora disease. Free Radic Biol Med. 2014 Oct;75 Suppl 1:S47. doi: 10.1016/j.freeradbiomed.2014.10.809. Epub 2014 Dec 10. PubMed PMID: 26461389.

10. López Del Amo V, Seco-Cervera M, García-Giménez JL, Whitworth AJ, Pallardó FV, Galindo MI. Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot-Marie-Tooth neuropathy. Hum Mol Genet. 2015 Jan 1;24(1):21-36. doi: 10.1093/hmg/ddu416. Epub 2014 Aug 13. PubMed PMID: 25122658.

11. Seco-Cervera M, Spis M, García-Giménez JL, Ibañez-Cabellos JS, Velázquez-Ledesma A, Esmorís I, Bañuls S, Pérez-Machado G, Pallardó FV. Oxidative stress and antioxidant response in fibroblasts from Werner and atypical Werner syndromes. Aging (Albany NY). 2014 Mar;6(3):231-45. PubMed PMID: 24799429; PubMed Central PMCID: PMC4012939.

12. García-Giménez JL, Òlaso G, Hake SB, Bönisch C, Wiedemann SM, Markovic J, Dasí F, Gimeno A, Pérez-Quilis C, Palacios O, Capdevila M, Viña J, Pallardó FV. Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure. Antioxid Redox Signal. 2013 Oct 20;19(12):1305-20. doi: 10.1089/ars.2012.5021. Epub 2013 May 21. PubMed PMID: 23541030; PubMed Central PMCID: PMC3791047.


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