GONZALO BLAY                                                              ASYMMETRIC SYNTHESIS AND CATALYSIS

Journal Publications 2012-

 

Authors (signature): Carlos Vila, Alejandra Rendón-Patiño, Marc Montesinos-Magraner, Gonzalo Blay, M. Carmen Muñoz, José R. Pedro

Title: Organocatalytic Enantioselective Functionalization of Hydroxyquinolines through an aza-Friedel-Crafts Alkylation with Isatin-derived Ketimines

Journal: Advanced Synthesis & Catalysis

Volume: 360 Number: --- Pages, Initial: 859 final: 864 Year: 2018 Place of publication: GERMANY ISSN: 1615-4150

 

Authors (signature): Pablo Martínez-Pardo; Gonzalo Blay; M. Carmen Muñoz; José R. Pedro; Amparo Sanz-Marco; Carlos Vila

Title: Enantioselective synthesis of chiral oxazolines from unactivated ketones and isocyanoacetate esters by synergistic silver/organocatalysis

Journal: Chemical Communications

Volume: 54 Number: --- Pages, Initial: 2862 final: 2865 Year: 2018 Place of publication: ENGLAND ISSN: 1359-7345

 

Authors (signature): Amparo Sanz-Marco, Gonzalo Blay, M. Carmen Muñoz, José R. Pedro

Title: Catalytic Enantioselective Conjugate Alkynylation of &&;,&&;-Unsaturated 1,1,1-Trifluoromethyl Ketones with Terminal Alkynes

Journal: Chemistry-A European Journal

Volume: 22 Number: --- Pages, Initial: 10057 final: 10064 Year: 2016 Place of publication: GERMANY ISSN: 0947-6539

 

Authors (signature): Carlos Vila; Andrés del Campo; Gonzalo Blay; José R. Pedro

Title: Catalytic Enantioselective Addition of Me₂Zn to Isatins

Journal: Catalysts

Volume: 7 Number: --- Pages, Initial: 387 final: --- Year: 2017 Place of publication: SWITZERLAND ISSN: 2073-4344

 

Authors (signature): Miguel Espinosa; Jorge Herrera; Gonzalo Blay; Luz Cardona; M. Carmen Muñoz; José R. Pedro

Title: Copper-catalysed enantioselective Michael addition of malonic esters to ²-trifluoromethyl-±,²-unsaturated imines

Journal: Organic & Biomolecular Chemistry

Volume: 15 Number: --- Pages, Initial: 3849 final: 3853 Year: 2017 Place of publication: ENGLAND ISSN: 1477-0520

 

Authors (signature): Miguel Espinosa, Gonzalo Blay, Luz Cardona, M. Carmen Muñoz, José R. Pedro

Title: Catalytic Asymmetric Formal [3+2] Cycloaddition of 2-Isocyanatomalonate Esters and Unsaturated Imines: Synthesis of Highly Substituted Chiral Lactams

Journal: Chemistry-A European Journal

Volume: 23 Number: --- Pages, Initial: 14707 final: 14711 Year: 2017 Place of publication: GERMANY ISSN: 0947-6539

 

Authors (signature): Marc Montesinos-Magraner; Carlos Vila; Gonzalo Blay; Isabel Ferna_ndez; M. Carmen Mun_oz; Jose_ R. Pedro

Title: Hydroxy-Directed Enantioselective Hydroxyalkylation in the Carbocyclic Ring of Indoles

Journal: Organic Letters

Volume: 19 Number: 7 Pages, Initial: 1546 final: 1549 Year: 2017 Place of publication: UNITED STATES ISSN: 1523-7060

Authors (signature): Carlos Vila; Lucia Quintero; Gonzalo Blay; M. Carmen Mun_oz; Jose_ R. Pedro

Title: Organocatalytic Enantioselective Synthesis of &&;_Hydroxyketones through a Friedel_Crafts Reaction of Naphthols and Activated Phenols with Aryl- and Alkylglyoxal Hydrates

Journal: Organic Letters

Volume: 18 Number: --- Pages, Initial: 5652 final: 5655 Year: 2016 Place of publication: UNITED STATES ISSN: 1523-7060

 

Authors (signature): Amparo Sanz-Marco; Gonzalo Blay; Carlos Vila; José R. Pedro

Title: Catalytic Enantioselective Conjugate Alkynylation of &&;-Aryl-&&;-trifluoromethyl Enones Constructing Propargylic All-Carbon Quaternary Stereogenic Centers

Journal: Organic Letters

Volume: 18 Number: --- Pages, Initial: 3538 final: 3541 Year: 2016 Place of publication: UNITED STATES ISSN: 1523-7060

 

Authors (signature): Marc Montesinos-Magraner; Carlos Vila; Alejandra Rendón-Patiño; Gonzalo Blay; Isabel Fernández; M. Carmen Muñoz; José R Pedro

Title: Organocatalytic Enantioselective Friedel-Crafts Aminoalkylation of Indoles in the Carbocyclic Ring

Journal: Acs Catalysis

Volume: 6 Number: --- Pages, Initial: 2689 final: 2693 Year: 2016 Place of publication: UNITED STATES ISSN: 2155-5435

 

Authors (signature): Marc Montesinos-Magraner; Carlos Vila; Gonzalo Blay; José R. Pedro

Title: Catalytic Enantioselective Friedel-Crafts Reactions of Naphthols and Electron-Rich Phenols

Journal: Synthesis-Stuttgart

Volume: 48 Number: --- Pages, Initial: 2151 final: 2164 Year: 2016 Place of publication: GERMANY ISSN: 0039-7881

 

Authors (signature): Fares Ibrahim Amr, Carlos Vila, Gonzalo Blay, M. Carmen Muñoz, José R. Pedro

Title: Organocatalytic Enantioselective Alkylation of Pyrazol-3-ones with Isatin-Derived Ketimines: Stereocontrolled Construction of Vicinal Tetrasubstituted Stereocenters

Journal: Advanced Synthesis & Catalysis

Volume: 358 Number: --- Pages, Initial: 1583 final: 1588 Year: 2016 Place of publication: GERMANY ISSN: 1615-4150

 

Authors (signature): Miguel Espinosa; Andrea García-Ortiz; Gonzalo Blay; Luz Cardona; M. Carmen Muñoz; José R. Pedro

Title: E,Z-Stereodivergent synthesis of N-tosyl &&;,&&;-dehydroamino esters via a Mukaiyama-Michael addition

Journal: Rsc Advances

Volume: 6 Number: --- Pages, Initial: 15655 final: 15659 Year: 2016 Place of publication: ENGLAND ISSN: 2046-2069

 

Authors (signature): Carlos Vila, Fares Ibrahim Amr, Gonzalo Blay, M. Carmen Muñoz, José R. Pedro

Title: Organocatalytic Enantioselective Synthesis of Pyrazoles Bearing a Quaternary Stereocenter

Journal: Chemistry-An Asian Journal

Volume: 11 Number: --- Pages, Initial: 1532 final: 1536 Year: 2016 Place of publication: GERMANY ISSN: 1861-4728

 

Authors (signature): Amparo Sanz-Marco; Gonzalo Blay; M. Carmen Muñoz; José R. Pedro

Title: Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to &&;,&&;-unsaturated trifluoromethyl ketones

Journal: Chemical Communications

Volume: 51 Number: --- Pages, Initial: 8958 final: 8961 Year: 2015 Place of publication: ENGLAND ISSN: 1359-7345

 

Authors (signature): Marc Montesinos-Magraner; Carlos Vila; Rubén Cantón; Gonzalo Blay; Isabel Fernández; M. Carmen Muñoz; José R. Pedro

Title: Organocatalytic Asymmetric Addition of Naphthols and Electron-Rich Phenols to Isatin-Derived Ketimines: Highly Enantioselective Construction of Tetrasubstituted Stereocenters

Journal: Angewandte Chemie

Volume: 54 Number: --- Pages, Initial: 6320 final: 6324 Year: 2015 Place of publication: GERMANY ISSN: 1433-7851

Comments:

 

Authors (signature): Marc Montesinos-Magraner; Rubén Cantón; Carlos Vila; Gonzalo Blay; Isabel Fernández; M. Carmen Muñoz; José R. Pedro

Title: Organocatalytic enantioselective aza-Friedel¿Crafts reaction of 2-naphthols with benzoxathiazine 2,2-dioxides

Journal: Rsc Advances

Volume: 5 Number: --- Pages, Initial: 60101 final: 60105 Year: 2015 Place of publication: ENGLAND ISSN: 2046-2069

 

Authors (signature): Melireth Holmquist; Gonzalo Blay; M. Carmen Muñoz; José R. Pedro

Title: Aza-Henry Reaction of Isatin Ketimines with Methyl 4-Nitrobutyrate en Route to Spiro[piperidine-3,3'-oxindoles]

Journal: Advanced Synthesis & Catalysis

Volume: 357 Number: --- Pages, Initial: 3587 final: 3862 Year: 2015 Place of publication: GERMANY ISSN: 1615-4150

 

Authors (signature): Marc Montesinos-Magraner; Carlos Vila; Gonzalo Blay; Isabel Fernández; M. Carmen Muñoz; José R. Pedro

Title: Organocatalytic enantioselective Friedel-Crafts alkylation of 1-naphthol derivatives and activated phenols with ethyl trifluoropyruvate

Journal: Advanced Synthesis & Catalysis

Volume: 357 Number: --- Pages, Initial: 3047 final: 3051 Year: 2015 Place of publication: GERMANY ISSN: 1615-4150

 

Authors (signature): Alicia Monleón, Gonzalo Blay, Luis R. Domingo, M. Carmen Muñoz, José R. Pedro

Title: Efficient Synthesis of 5-Chalcogenyl-1,3-oxazin-2-ones by Chalcogen-Mediated Yne¿Carbamate Cyclisation: An Experimental and Theoretical Study

Journal: European Journal of Organic Chemistry

Volume: --- Number: --- Pages, Initial: 1020 final: 1027 Year: 2015 Place of publication: GERMANY ISSN: 1434-193X

 

Authors (signature): Melireth Holmquist; Gonzalo Blay; José R. Pedro

Title: Highly enantioselective aza-Henry reaction with isatin N-Boc ketimines

Journal: Chemical Communications

Volume: 50 Number: --- Pages, Initial: 9309 final: 9312 Year: 2014 Place of publication: ENGLAND ISSN: 1359-7345

 

Authors (signature): Solinas, Maurizio; Sechi, Barbara; Chelucci, Giorgio; Baldino, Salvatore; Pedro, José R.; Blay, Gonzalo

Title: Synthesis and application of new iminopyridine ligands in the enantioselective palladium-catalyzed allylic alkylation

Journal: Journal of Molecular Catalysis A-Chemical

Volume: 385 Number: --- Pages, Initial: 73 final: 77 Year: 2014 Place of publication: NETHERLANDS ISSN: 1381-1169

 

Authors (signature): Amparo Sanz-Marco; Andrea Garcí_a-Ortiz; Gonzalo Blay; Isabel Ferná_ndez; José R. Pedro

Title: Highly Enantioselective Copper(I)-Catalyzed Conjugate Addition of Terminal Alkynes to 1,1-Difluoro-1-(phenylsulfonyl)-3-en-2- ones: New Ester/Amide Surrogates in Asymmetric Catalysis

Journal: Chemistry-A European Journal

Volume: 20 Number: --- Pages, Initial: 668 final: 672 Year: 2014 Place of publication: GERMANY ISSN: 0947-6539

 

Authors (signature): Amparo Sanz-Marco; Andrea Garcí_a-Ortiz; Gonzalo Blay; José R. Pedro

Title: Catalytic asymmetric conjugate addition of terminal alkynes to &&;-trifluoromethyl &&;,&&;-enones.

Journal: Chemical Communications

Volume: 50 Number: --- Pages, Initial: 2275 final: 2278 Year: 2014 Place of publication: ENGLAND ISSN: 1359-7345

 

Authors (signature): Melireth Holmquist; Gonzalo Blay; M. Carmen Muñoz; José R. Pedro

Title: Enantioselective Addition of Nitromethane to 2-Acylpyridine N-Oxides. Expanding the Generation of Quaternary Stereocenters with the Henry Reaction

Journal: Organic Letters

Volume: 16 Number: 4 Pages, Initial: 1204 final: 1207 Year: 2014 Place of publication: UNITED STATES ISSN: 1523-7060

 

Authors (signature): Gonzalo Blay; Rosa M. Girón; Marc Montesinos-Magraner; José R. Pedro

Title: Leaving Group and Regioselectivity Switches in the Aminoalkylation Reaction of Indoles and Related Heterocycles with ±-Amido Sulfones

Journal: European Journal of Organic Chemistry

Volume: --- Number: --- Pages, Initial: 3885 final: 3895 Year: 2013 Place of publication: GERMANY ISSN: 1434-193X

 

Authors (signature): Gonzalo Blay; Isabel Fernández; M. Carmen Muñoz; José R. Pedro; Carlos Vila

Title: Enantioselective Friedel-Crafts Alkylation of Indoles with (E)-1-Aryl-4-benzyloxybut-2-en-1-ones Catalyzed by an (R)-3,3'-Br₂BINOLate-Hafnium(IV) Complex

Journal: European Journal of Organic Chemistry

Volume: --- Number: --- Pages, Initial: 1902 final: 1907 Year: 2013 Place of publication: GERMANY ISSN: 1434-193X

 

Authors (signature): Gonzalo Blay; Celia Incerti; M. Carmen Muñoz; José R. Pedro

Title: Enantioselective La^III-pyBOX-Catalyzed Nitro-Michael Addition to (E)-2-Azachalcones

Journal: European Journal of Organic Chemistry

Volume: --- Number: --- Pages, Initial: 1696 final: 1705 Year: 2013 Place of publication: GERMANY ISSN: 1434-193X

 

Authors (signature): Miguel Espinosa; Gonzalo Blay; Luz Cardona, José R. Pedro

Title: Asymmetric conjugate addition of malonate esters to &&;,&&;-unsaturated N-sulfonylimines: An expeditious route to chiral &&;-aminoesters and piperidones

Journal: Chemistry-A European Journal Resaltat a ChemistryViews website

Volume: 19 Number: --- Pages, Initial: 14861 final: 14866 Year: 2013 Place of publication: GERMANY ISSN: 0947-6539

 

Authors (signature): Alicia Monleón; Gonzalo Blay; Luis R. Domingo; M. Carmen Muñoz; José R. Pedro

Title: Synthesis of densely functionalised 5-halogen-1,3-oxazin-2-ones by halogen-mediated regioselective cyclisation of N-Cbz-protected propargylic amines: A combined experimental and theoretical study

Journal: Chemistry-A European Journal

Volume: 19 Number: --- Pages, Initial: 14852 final: 14860 Year: 2013 Place of publication: GERMANY ISSN: 0947-6539

 

Authors (signature): Gonzalo Blay; M. Carmen Muñoz; José R. Pedro; Amparo Sanz-Marco

Title: Enantioselective Synthesis of 4-Substituted Dihydrocoumarins through a Zinc Bis(hydroxyamide)-Catalyzed Conjugate Addition of Terminal Alkynes

Journal: Advanced Synthesis & Catalysis

Volume: 355 Number: --- Pages, Initial: 1071 final: 1076 Year: 2013 Place of publication: GERMANY ISSN: 1615-4150

 

Authors (signature): Gonzalo Blay; Ana Escamilla; Victor Hernández-Olmos; José R. Pedro; Amparo Sanz-Marco

Title: Enantioselective copper-aminopyridine-catalyzed aza-Henry reaction with chelating N-(2-pyridyl)sulfonyl imines

Journal: Chirality USA

Volume: 24 Number: --- Pages, Initial: 441 final: 450 Year: 2012 Place of publication: UNITED STATES ISSN: 0899-0042

 

Authors (signature): Gonzalo Blay; Isabel Fernández; José R. Pedro; Carlos Vila

Title: Enantioselective synthesis of substituted indoles through zirconium(IV)-catalyzed Friedel-Crafts alkylation

Journal: Synthesis-Stuttgart

Volume: 44 Number: --- Pages, Initial: 3590 final: 3594 Year: 2012 Place of publication: GERMANY ISSN: 0039-7881

 

Authors (signature): Gonzalo Blay; Ana Brines; Alicia Monleón; José R. Pedro

Title: Enantioselective Zn/BINOL-catalysed alkynylation of aldimines generated in situ from &&;-amido sulfones

Journal: Chemistry-A European Journal

Volume: 18 Number: --- Pages, Initial: 2440 final: 2444 Year: 2012 Place of publication: GERMANY ISSN: 0947-6539

 

Authors (signature): Gonzalo Blay; Eric Ceballos; Alicia Monleón; José R. Pedro

Title: Enantioselective addition of terminal alkynes to N-(diphenylphosphinoyl)imines catalyzed by Zn-BINOL complexes

Journal: Tetrahedron

Volume: 68 Number: --- Pages, Initial: 2129 final: 2134 Year: 2012 Place of publication: ENGLAND ISSN: 0040-4020

 

Authors (signature): Gonzalo Blay; Luz Cardona; José R. Pedro; Amparo Sanz-Marco

Title: Enantioselective Zn-mediated conjugate addition of terminal alkynes to enones

Journal: Chemistry-A European Journal

Volume: 18 Number: --- Pages, Initial: 12966 final: 12969 Year: 2012 Place of publication: GERMANY ISSN: 0947-6539

 

Authors (signature): Gonzalo Blay; Joan Cano; Luz Cardona; Isabel Fernández; M. Carmen Muñoz; José R. Pedro; Carlos Vila

Title: NMR spectroscopic characterization and DFT calculations of zirconium(IV)-3,3'-Br2-BINOLate and related complexes used in an enantioselective Friedel-Crafts alkylation of indoles with ±,²-unsaturated ketones

Journal: Journal of Organic Chemistry

Volume: 77 Number: 23 Pages, Initial: 10545 final: 10556 Year: 2012 Place of publication: UNITED STATES ISSN: 0022-3263

 

 

Book Publications

 

 

Authors (signature): Gonzalo Blay; Marc Montesinos Magraner; José R. Pedro

Title: Friedel-Crafts Alkylation of Arenes in Total Synthesis

Book: Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds. Jacques Mortier Ed.

Publisher: Wiley

Volume: --- Number: --- Pages, Initial: 33 final: 58 Year: 2016 Place of publication: Hoboken, New Jersey (UNITED STATES) ISBN: 978-1-118-75201-2 Legal Deposit: ---

 

Also available in Amazon