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Publicaciones del año 2011

Snake venomics of African spitting cobras: Toxin composition and assessment of congeneric cross-reactivity of the Pan-African EchiTAb-Plus-ICP® antivenom by antivenomics and neutralization approaches
Petras, D., Sanz, L., Segura, A., Herrera, M., Villalta, M., Solano, D., Vargas, M., León, G., Warrell, D.A., Theakston, R.D.G., Harrison, R.A., Durfa, N., Nasidi, A., Gutiérrez, J.M. & Calvete, J.J.
J. Proteome Res. 10 (2011) 1266-1280

Snake population venomics and antivenomics of Bothrops atrox: paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management
Calvete, J.J., Sanz, L., Pérez, A., Borges, A., Vargas, A.M., Lomonte, B., Angulo, Y., Gutiérrez, J.M., Chalkidis, H.M., Mourão, R.H.V., Furtado, M.F.D. & Moura da Silva, A.M.
J. Proteomics 74 (2011) 510-527

Venomic and antivenomic analyses of the Central American coral snake, Micrurus nigrocinctus (Elapidae)
Fernández, J., Alape-Girón, A., Angulo, Y., Sanz, L., Gutiuérrez, J., Calvete, J.J. & Lomonte, B.
J. Proteome Res. 10 (2011) 1816–1827

Snake venomics and venom gland tranacriptomic analysis of Brazilian coral snakes, Micrurus altirostris and M. corallinus
Corrêa-Netto, C., Junqueira de Azevedo, I.L.M., Silva, D.A., Ho, P.L., Leitão de Araujo, M., Alves, M.L.M., Sanz, L., Foguel, D., Zingali, R.B. & Calvete, J.J.
J. Proteomics 74 (2011) 1795-1809

Profiling venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing
Durban, J., Juárez, P., Angulo, Y., Lomonte, B., Flores-Diaz, M., Alape-Girón, A., Sasa, M., Sanz, L., Gutiérrez, J.M., Dopazo, J., Conesa, A. & Calvete, J.J.
BMC Genomics 12:259 (2011)

NMR structure and dynamics of recombinant wild-type and mutated jerdostatin, a selective inhibitor of integrin α1β1
Carbajo, R.J., Sanz, L., Mosulén S., Pérez, A., Marcinkiewicz, C., Pineda-Lucena, A. & Calvete, J.J.
PROTEINS: Structure, Function, and Bioinformatics 79 (2011) 2530-2534

Proteomic analysis of ontogenetic and diet-related changes in venom composition of juvenile and adult Dusky Pigmy rattlesnakes (Sistrurus miliarius barbouri)
Gibbs, H.L., Sanz, L., Chiucchi, J.E., Farrell, T.M. & Calvete, J.J.
J. Proteomics 74 (2011) 2169-2179

Temperature-controlled release via paraffin-capped mesoporous silica nanoparticles
Aznar E., Mondragón L., Ros-Lis, J.V, Sancenón, F., Marcos, M.D., Martínez-Máñez, R.*, Soto, J., Pérez-Payá, E., Amorós, P.
Angewandte Chemie Int Ed (in press)

Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1
Sancho M., Herrera, A.E., Gortat, A., Carbajo, R.J., Pineda-Lucena, A., Orzáez, M., Pérez-Payá E.
Human Mol Gen 20(18) 3545-53 (2011)

Click chemistry anchoring of peptide sequences for the design of enzyme-mediated controlled release systems based on silica mesoporous supports
Coll, C., Mondragón, L., Martínez-Máñez, R., Sancenón, F., Marcos, M.D., Soto, J., Amorós, P., Pérez-Payá E.
Angewandte Chemie Int Ed 50(9), 2138-40 (2011)

Characterization of Dequalinium as a XIAP antagonist that targets the BIR2 domain
Orzáez, M., Gortat, A., Sancho M., Carbajo, R.J., Pineda-Lucena, A., Palacios-Rodríguez, Y., Pérez-Payá E.
Apoptosis 10(5), 460-7 (2011)

Molecules that modulate Apaf-1 activity
Pérez-Payá, E., Orzáez, M., Mondragón, L., Wolan, D., Wells, J.A., Messeguer, A., Vicent, M.J.
Medicinal Research Reviews 31(4), 649-675 (2011)

Membrane protein integration into the endoplasmic reticulum.
Martínez-Gil L, Saurí A, Marti-Renom MA, Mingarro I.
FEBS J. 2011 May 19. doi: 10.1111/j.1742-4658.2011.08185.x.

Membrane insertion and topology of the translocating chain-associating membrane protein (TRAM).
Tamborero S, Vilar M, Martínez-Gil L, Johnson AE, Mingarro I.
J Mol Biol. 2011 Mar 4;406(4):571-82.

N-glycosylation efficiency is determined by the distance to the C-terminus and the amino acid preceding an Asn-Ser-Thr sequon.
Bañó-Polo M, Baldin F, Tamborero S, Marti-Renom MA, Mingarro I.
Protein Sci. 2011 Jan;20(1):179-86.

Publicaciones del año 2010

Recombinant expression in human cells of active integrin a1b1-blocking RTS-disintegrin jerdostatin
Juárez, P., Bolás, G., de Rezende, F.F., Calvete, J.J. & Eble, J.A.
Toxicon 56 (2010) 1052-1058

Enzyme-responsive intracellular controlled release using nanometric silica mesoporous supports capped with ‘saccharides’.
Bernardos, A., Mondragón, L., Aznar, E., Marcos, M.D., Martínez-Máñez, R., Sancenón, F., Soto, J., Barat, J.M., Pérez-Payá E., Guillem, C., Amorós, P.
ACS Nano 4(11), 6353-68 (2010)

© 2011. PROMETEO 2010 005: Identificación de nuevas dianas terapéuticas en angiogénesis y apoptosis basadas en interacciones proteína-proteína