Viral mutation rates
This
on-line resource contains estimates of
the spontaneous mutation rate for 25
different viruses.
Several
independent estimates are available for
some viruses.
Viral
mutation rates can be expressed as
substitutions per nucleotide site per cell
infection (s/n/c) or as substitutions per
nucleotide per strand copying (s/n/r).
Mutation
rates per cell infection
Mutation
rates per strand copying
The goal of
this site is to provide an easily
available, curated data set on viral
mutation rates and to promote the use of
common units. References to original
publications and methodological details of
each estimate are provided.
Data are
taken from the following article, which
also contains a detailed description of
the methods used:
Sanjuán R.,
Nebot M.R., Chirico N., Mansky L.M.,
Belshaw R. (2010). Viral mutation rates. J. Virol. 84:
9733-9748. [pdf]
A few more
recent estimates that do not appear in
the above paper have been added.
The data
span from the late 70´s until 2013. Please
check Sanjuán and Domingo-Calap (2016) for newer estimates.
Rafael
Sanjuán, Institute for Integrative Systems Biology
University of Valencia, Spain
Tel: +34 963 543 270
E-mail: rafael.sanjuan@uv.es
Mailing address: Institute for Integrative Systems Biology
Parc Cientific de la Universitat de Valencia
C/ Catedratico Agustin Escardino n° 9
46980 Paterna, Valencia
Spain