This study aims to assess the ability of a FTIR methodology to establish DKD diagnostic models applicable across diverse populations, instruments and experimental conditions worldwide. Results evidence that the spectral markers found in the IR spectra, based on signals arising from albumin and other glycoproteins, have proven to be robust, minimizing the effects of population and instrument variability. doi
A research team from 70 institutions, led by Cardiff University (United Kingdom) and the University of Wuppertal (Germany), and including Ángel Sánchez Illana from the University of Valencia (UV), has developed a guide of best practice recommendations for the analysis of oxylipins using liquid chromatography coupled with mass spectrometry (LC-MS/MS). The work was published on Tuesday in the journal Science Signaling.
uvnoticias: link
This study presents an automated, data-driven workflow for exploring drug metabolism in Upcyte human hepatocytes, focusing on α-pyrrolidinoisohexiophenone (a synthetic cathinone). Our approach reveals metabolic differences that may be linked to individual-specific profiles—highlighting the potential of combining high-content metabolomics with automated analysis to better understand inter-individual variability in drug metabolism. doi
Dr. Ángel Sánchez Illana delivered a community talk at the mzmine Community Meeting, held at the Institute of Organic Chemistry and Biochemistry (IOCB) in Prague. This international event brought together mzmine developers, experienced users, and newcomers to exchange knowledge, explore new features, and foster collaborative development of the open-source platform.
In his talk, titled "mzmine Meets LluisVives HPC: Untargeted Oxylipin Profiling in 491 Human Urine Samples", Ángel shared insights from our group's integration of high-performance computing (HPC) with mzmine for large-scale untargeted metabolomics, highlighting computational strategies and challenges encountered when processing hundreds of LC-MS datasets.
We're excited to announce the arrival of our newest instrument, the Alpha II Spectrometer from Bruker, a compact FT-IR spectrometer with a footprint the size of a laptop. We are looking forward to analyse new samples both in an out of the lab!
We had the pleasure to assist to the SPEC 2024 where Víctor presented his poster about the development of a global model fir CKD diagnosis using ATR-FTIR and David Perez Guaita talked about spectroscopy based urine screening in the Data science session.
Great experience at the ALBA synchrotron to dig into NPS toxicity in cells using IR light. Thanks heaps to Tanja and the funding from
@AgEInves. Stay tuned for the scoop!
We are pleased to announce that in the ICAVS 2023 held in Krakow David received an award for its contribution as young researcher to the field of vibrational spectroscopy.
Drag and Drop Website Builder
Follow us