Prometeo Smart-Chemical-LAB

Departamento de Química Analítica, Universidad de Valencia

Prometeo Smart-Chemical-LAB

Smart-Chemical-LAB is a project to develop an interdisciplinary, sustainable and portable analytical chemistry laboratory combining resources from the fields of Analytical Chemistry, Food Technology, Optics, Forensics, Chemometrics, Environmental, and Cultural Heritage. Smart-Chemical-LAB aims to develop sustainable analytical methods, combining signals from portable instrumentation and specifically designed 3D-printed analytical Arduino-based devices and smartphone data acquisition. The fast on-site data acquisition process, permits real-time decisions to be made for problem-solving in areas that, though different, share similar problems, and that would benefit from the reduction in reagent consumption, the use of portable equipment, non-invasive and non-destructive techniques, based in low-cost but precise and robust technology.
The transfer of the project’s outcomes to public and private institutions will benefit and reduce costs in quality and safety food controls and reduce food waste due to inappropriate decisions during farming and harvesting. Moreover, the application of such direct, in-field and portable technology in the forensic sector will reduce the risks related to the consumption of psychoactive substances and will provide very useful tools for law enforcement interventions. Thanks to the collaboration with different museums, the methods developed in the field of Cultural Heritage valorization and conservation can be transferred to society in general and to Valencian Museums in particular.
Regarding the applications of environmental analysis, the need to know the levels of contaminants to keep the environment safe and clean is a social demand. Having in situ, simple and quick procedures to control the quality of water, soil and crops will enable decision making in real time, not only to minimize the content of contaminants found, but can also help to counteract the micronutrient deficiency in crops.

Team members

The members of the team have extensive research experience research experience covering various fields such as analytical chemistry, image processing, food, forensic and environmental analysis, as well as materials science and chemometric data processing.
Regarding the Analytical Chemistry area, the principal investigator (PI) (Dr. M.L. Cervera) and three other members of the team (Dr. A. Morales, Dr. A. Mauri and Dr. J. Verdú) belong to the Department of Analytical Chemistry and have a wide experience in the use of very diverse instrumentation, both fixed and portable, the development of analytical methods and their application to the fields of environmental and their application to the fields of environmental analysis, agri-food, forensics and archaeometry. Dr. Rafael Ibañez, from the Department of Inorganic Chemistry, is an expert in materials science and has extensive experience in the transfer of research results to industry. In addition, the PI is a specialist in food analysis, having obtained the title of High Specialization in Food Technology (IATA - CSIC), and completed her PhD Thesis at this center. 

In addition, the research team includes Dr. Jordi Cruz and Dr. Manel Alcalà, specialists in data processing and chemical imaging, as well as in the application of chemometric techniques for the extraction of valuable information.

The research team is completed with doctoral students, as well as with the collaboration of Dr. G. Gallello, of the Department of Prehistory, Archaeology and Ancient History. In addition, Dr. A. Mauri has a degree in History, which completes the multidisciplinary background of the team.

Maria Luisa Cervera
Analytical Chemistry Department
University of Valencia

Angel Morales
Analytical Chemistry Department
University of Valencia

Adela Mauri
Analytical Chemistry Department
University of Valencia

Jorge Verdu
Analytical Chemistry Department
University of Valencia

Roberto Saez
Analytical Chemistry Department
University of Valencia

Rafael Ibañez
Inorganic Chemistry Department
University of Valencia

Manel Alcalà
Analytical Chemistry Department
Universitat Autonoma de Barcelona

Jordi Cruz
Analytical Chemistry Department
Escola Universitaria Salesiana Sarrià (EUSS)

Scientific publications

Group’s expertise and background in the proposed studies 

Multicommutation based-papers:

1

Improvement of the atomic fluorescence determination of mercury I by using multicommutation.

Reis BF, Ródenas-Torralba E, Sancenón-Buleo J, Morales-Rubio A, de la Guardia M. (2002)  J. Anal. At. Spectrom. 17, 537-540.

2

Multicommutation as an environmentally friendly analytical tool in the hydride generation atomic fluorescence determination of tellurium in milk. 

Ródenas-Torralba E, Cava-Montesinos P, Morales-Rubio A, Cervera Sanz ML, de la Guardia M. (2004) Anal. Bioanal. Chem. 379, 83-89.

3

Multicommutation ATR-FTIR: determination of sodium alpha-olefin sulfonate in detergent formulations. 

Ventura-Gayete J, Reis BF, Garrigues S, Morales-Rubio A, de la Guardia M. (2004) Microchem. J. 78, 47-54.

4

An environmentally friendly multicommutated alternative to the reference method for anionic surfactant determination in water. 

Ródenas-Torralba E, Reis BF, Morales-Rubio A, de la Guardia M. (2005) Talanta 66, 591-599.

5

Determination of phenols in waters using micro-pumped multicommutation and spectrophotometric detection: an automated alternative to the standard procedure.

Ródenas-Torralba E, Morales-Rubio A, de la Guardia M. (2005)  Anal. Bioanal. Chem. 383, 138-144.

6

Monitoring of the smoking process by multicommutation FTIR spectroscopy.

Lavorante AF, Garrigues S, Reis BF, Morales-Rubio A, de la Guardia M. (2007)  Anal. Chim. Acta 593, 39-45.

7

Micropumping multicommutation turbidimetric analysis of Waters.

Ródenas-Torralba E, Morales-Rubio A, Lavorante AF, Reis BF, de la Guardia M. (2007)  Talanta 73, 742-747.

8

A Multicommuted flow system with solenoid micro-pumps for paraquat determination in natural Waters.

Infante CMC, Morales A, de la Guardia M, Rocha FRP. (2008)  Talanta 75, 1376-1381.

9

Sequential spectrofluorimetric determination of free and total glycerol in biodiesel in a multicommuted flow system. 

Silva SG, Morales-Rubio A, de la Guardia M, Rocha FRP. (2011) Anal. Bioanal. Chem. 401, 365-371.

“Smartphone and Green Chemistry” based-papers:

1

Phosphate determination in environmental, biological and industrial samples using a smartphone as a capture device.

Sáez-Hernández R, Mauri-Aucejo, AR, Morales-Rubio A, Pastor A, Cervera ML. (2022)  New J. Chem. 46, 1286-1294.

2

Determination of acrylamide in toasts using digital image colorimetry by smartphone.

Sáez-Hernández R, Ruiz P, Mauri-Aucejo AR, Yusa V, Cervera ML. (2022) Food Control 141, 109163.

3

Determinación de quinina en tónicas mediante tratamiento de imagen.

Antela KU, Ochoa-Ballesteros A, Sáez-Hernández R, Cervera ML, Pastor A, Luque MJ, Morales-Rubio A. (2022)  XIII Congreso nacional de color.

4

Smartphone-based colorimetric study of adulterated tuna samples.

Sáez-Hernández R, Antela KU, Mauri-Aucejo AR, Morales-Rubio A, Cervera ML. (2022).  Food Chem. 389, 133063.

5

A fast and non-invasive imaging procedure to fight red tuna fraud.

Sáez-Hernández R, Antela KU, Mauri-Aucejo AR, Morales-Rubio A, Luque MJ, Cervera ML. (2023)  LWT, 186, 115231.

6

Development of an automated colorimeter controlled by Raspberry Pi4.

Antela K, Sáez-Hernández R, Cervera ML, Morales-Rubio, A, Luque MJ. (2023)  Analytical Methods 15(4), 512-518.

7

Smartphone application for ancient mortars identification developed by a multi-analytical approach. 

Ramacciotti M, Gallello G, Lezzerini M, Pagnotta S, Aquino A, Alapont L, Martín-Ruiz JA, Pérez-Malumbres Landa A, Hiraldo Aguilera R, Godoy Ruiz D, Morales-Rubio A, Cervera ML, Pastor A. (2022) J. Arch. Sci. Rep. 43, 103433.

8

A smartphone-based innovative approach to discriminate red pigments in roman frescoes mock-ups.

Sáez-Hernández R, Antela KU, Gallello G, Cervera ML, Mauri-Aucejo AR. (2022) J. Cult. Herit. 58, 156-166.

Research activities

The general aim of Smart-Chemical-LAB is to develop portable laboratories employing fast analytical methods based on imaging, colorimetric and spectrometric multianalytical approaches, including mobile phones as a data acquisition system, coupled with Arduino devices in the environmental protection, food safety, forensic analysis and cultural heritage areas.
The Project is subdivided in specific objectives related to three main categories: Design and manufacturing of especially devoted 3D printed devices combined with mechanized parts controlled by Arduino using the smartphone and TCS34725 sensors as detectors, characterization and optimization of the smartphone based methodologies and finally application of the “lab-on-a-phone” concept to the different sectors.

Design and manufacturing of analytical devices

A. Design and manufacturing of the 3D printed parts of the analytical devices.
B. Assembly of the 3D printed accessories to the mechanized parts controlled by Arduino.
C. Final development of mechanized portable labs to carry out chemical reactions using smartphone and TCS34725 sensors as detectors.

Characterization and optimization of the smartphone based methodologies

A. Colorimetric characterization of the cameras of phones under changing illumination conditions, using
standard and custom-designed color charts.
B. Development of user-friendly software to compute color descriptors with the appropriate colorimetric
characterization models that could be used in computers and easily adapted for smartphone
applications.
C. Verification of the utility of the models and devices obtained.

“Lab-on-a-phone” as analytical platform in different application areas

Smart-Chemical-LAB in Environmental applications
● Development of kits and automated systems to determine copper content in water using a specially designed
app and a Smartphone as detector.
● Determination of PAHs in water samples using 3D-printed devices and smartphone-based methodologies.
● In situ determination in soils of the required micronutrients for adequate crop growth.

Smart-Chemical-LAB in Agri-Food applications
● Development of a smartphone application for quality control of vegetables at harvest time, and prediction of
shelf-life based on sensory quality.
● Determination of aflatoxins in food using 3D-printed devices and smartphone-based methodologies.

Smart-Chemical-LAB in Cultural Heritage applications
● Analytical applications for Cultural Heritage including metal objects, ancient paintings, building materials
among others.

Smart-Chemical-LAB in Forensic Analysis
● Preliminary identification of illicit drugs using colorimetric reactions.
● Development of analytical devices for the determination of synthetic cannabinoids using a low-cost smartphone fluorometer.

Outreach activities

Under construction. We will be available shortly...

Mobirise

Collaborations

Mobirise

Prof. José Manuel Herrero. CLECEM research group, University of Valencia. 

Specialists in the development of smart materials for sample preparation and separation techniques with enhanced characteristics.

Mobirise

Prof. Pedro Amorós, Grupo de Materiales Nanoestructurados, Instituto de Ciencia de la Materiales (ICMUV), Universitat de València. 

Specialists in the synthesis and characterization of new functionalized mesoporous materials.

Mobirise

Prof. Gianni Gallello, Dept. of Prehistory, Archaeology and Ancient History, University of Valencia

ArchaeChemis is a research unit which was born between the Department of Analytical Chemistry and the Department of Prehistory, Archaeology and Ancient History of the University of Valencia.

Mobirise

IRTA, Food Quality and Technology Program, Finca Camps i Armet, s/n, Girona, Monells, 17121, Spain

 

Financiado por:

Generalitat Valenciana
PROMETEO CIPROM/2023/37

Dirección

Edificio Jeronimo Muñoz,
Doctor Moliner, 50
46100 Burjassot, Valencia

 

 

Contacto

Email: cslab@uv.es
Phone:  +34 96354 3486

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