Publications
2022
Perea-García A, Puig S, Peñarrubia L. The role of post-transcriptional modulators of metalloproteins in response to metal deficiencies. J Exp Bot. 2022. 73(6):1735-1750. doi: 10.1093/jxb/erab521.
2021
Perea-García A, Andrés-Bordería A, Huijser P, Peñarrubia L. The Copper-microRNA Pathway Is Integrated with Developmental and Environmental Stress Responses in Arabidopsis thaliana. Int J Mol Sci. 2021. 22(17):9547. doi: 10.3390/ijms22179547.
Romero P, Gabrielli A, Sampedro R, Perea-García A, Puig S, Lafuente MT. Identification and molecular characterization of the high-affinity copper transporters family in Solanum lycopersicum. Int J Biol Macromol. 2021. 192:600-610. doi: 10.1016/j.ijbiomac.2021.10.032.
2020
Perea-García A, Andrés-Bordería A, Vera-Sirera F, Pérez-Amador MA, Puig S, Peñarrubia L. Deregulated High Affinity Copper Transport Alters Iron Homeostasis in Arabidopsis. Front Plant Sci. 2020. 11:1106. doi: 10.3389/fpls.2020.01106.
2019
Escaray FJ, Antonelli CJ, Copello GJ, Puig S, Peñarrubia L, Ruiz OA, Perea-García A. Characterization of the Copper Transporters from Lotus spp. and Their Involvement under Flooding Conditions. Int J Mol Sci. 2019. 20(13):3136. doi: 10.3390/ijms20133136.
Carrió-Seguí À, Ruiz-Rivero O, Villamayor-Belinchón L, Puig S, Perea-García A, Peñarrubia L. The Altered Expression of microRNA408 Influences the Arabidopsis Response to Iron Deficiency. Front Plant Sci. 2019. 10:324. doi: 10.3389/fpls.2019.00324.
Carrió-Seguí À, Romero P, Curie C, Mari S, Peñarrubia L. Copper transporter COPT5 participates in the crosstalk between vacuolar copper and iron pools mobilisation. Sci Rep. 2019. 9(1):4648. doi: 10.1038/s41598-018-38005-4.
Sanz A, Pike S, Khan MA, Carrió-Seguí À, Mendoza-Cózatl DG, Peñarrubia L, Gassmann W. Copper uptake mechanism of Arabidopsis thaliana high-affinity COPT transporters. Protoplasma. 2019. 256(1):161-170. doi: 10.1007/s00709-018-1286-1.
2018
Andrés-Colás N, Carrió-Seguí A, Abdel-Ghany SE, Pilon M, Peñarrubia L. Expression of the Intracellular COPT3-Mediated Cu Transport Is Temporally Regulated by the TCP16 Transcription Factor. Front Plant Sci. 2018. 9:910. doi: 10.3389/fpls.2018.00910.eCollection 2018.
2017
Andrés-Bordería A, Andrés F, Garcia-Molina A, Perea-García A, Domingo C, Puig S, Peñarrubia L. Copper and ectopic expression of the Arabidopsis transport protein COPT1 alter iron homeostasis in rice (Oryza sativa L.). Plant Mol Biol. 2017. 95(1-2):17-32. doi: 10.1007/s11103-017-0622-8.
Tiwari M, Venkatachalam P, Penarrubia L, Sahi SV. COPT2, a plasma membrane located copper transporter, is involved in the uptake of Au in Arabidopsis. Sci Rep. 2017. 7(1):11430. doi: 10.1038/s41598-017-11896-5.
2016
Carrió-Seguí À, Romero P, Sanz A, Peñarrubia L. Interaction Between ABA Signaling and Copper Homeostasis in Arabidopsis thaliana. Plant Cell Physiol. 2016. 57(7):1568-1582. doi: 10.1093/pcp/pcw087.
Perea-García A, Sanz A, Moreno J, Andrés-Bordería A, de Andrés SM, Davis AM, Huijser P, Davis SJ, Peñarrubia L. Daily rhythmicity of high affinity copper transport. Plant Signal Behav. 2016. 11(3):e1140291. doi: 10.1080/15592324.2016.1140291.
Perea-García A, Andrés-Bordería A, Mayo de Andrés S, Sanz A, Davis AM, Davis SJ, Huijser P, Peñarrubia L. Modulation of copper deficiency responses by diurnal and circadian rhythms in Arabidopsis thaliana. J Exp Bot. 2016. 67(1):391-403. doi: 10.1093/jxb/erv474.
2015
Peñarrubia L, Romero P, Carrió-Seguí A, Andrés-Bordería A, Moreno J, Sanz A. Temporal aspects of copper homeostasis and its crosstalk with hormones. Front Plant Sci. 2015. 6:255. doi: 10.3389/fpls.2015.00255.eCollection 2015
Carrió-Seguí A, Garcia-Molina A, Sanz A, Peñarrubia L. Defective copper transport in the copt5 mutant affects cadmium tolerance. Plant Cell Physiol. 2015. 56(3):442-54. doi: 10.1093/pcp/pcu180.
2014
Puig S. Function and Regulation of the Plant COPT Family of High-Affinity Copper Transport Proteins. Advances in Botany. 2014. Article ID 476917, 9 pages. doi:10.1155/2014/476917.
2013
García-Molina A, Andrés-Colás N, Perea-García A, Neumann U, Dodani SC, Huijser P, Peñarrubia L, Puig S. The Arabidopsis COPT6 transport protein functions in copper distribution under copper-deficient conditions. Plant Cell Physiol. 2013. 54(8): 1378-1390. doi: 10.1093/pcp/pct088.
Andrés-Colás N, Perea-García A, Mayo de Andrés S, Garcia-Molina A, Dorcey E, Rodríguez-Navarro S, Pérez-Amador MA, Puig S, Peñarrubia L. Comparison of global responses to mild deficiency and excess copper levels in Arabidopsis seedlings. Metallomics. 2013. 5(9): 1234-1246. doi: 10.1039/c3mt00025g.
Perea-García A, Garcia-Molina A, Andrés-Colás N, Vera-Sirera F, Pérez-Amador MA, Puig S, Peñarrubia L. Arabidopsis Copper Transport Protein COPT2 Participates in the Cross Talk between Iron Deficiency Responses and Low Phosphate Signaling. Plant Physiol. 2013. 162(1): 180-194. doi: 10.1104/pp.112.212407.
2012
Rodrigo-Moreno A, Andrés-Colás N, Poschenrieder C, Gunsé B, Peñarrubia L, Shabala S. (2012). Calcium- and potassium-permeable plasma membrane transporters are activated by copper in Arabidopsis root tips: linking copper transport with cytosolic hydroxyl radical production. Plant Cell Environ. doi: 10.1111/pce.12020. PubMed
2011
Garcia-Molina A, Andrés-Colás N, Perea-García A, Del Valle-Tascón S, Peñarrubia L, Puig S (2011). The intracellular Arabidopsis COPT5 transport protein is required for photosynthetic electron transport under severe copper deficiency. Plant J. 65(6): 848-60. PubMed
2010
Perea-García A, Andrés-Colás N, Peñarrubia L (2010). Copper homeostasis influences the circadian clock in Arabidopsis. Plant Signal Behav. 5(10). [Epub ahead of print] PubMed PMID: 20861682. PubMed
Andrés-Colás N, Perea-García A, Puig S, Peñarrubia L (2010). Deregulated copper transport affects Arabidopsis development especially in the absence of environmental cycles. Plant Physiol. 153(1): 170-84. PubMed
Peñarrubia L, Andrés-Colás N, Moreno J, Puig S (2010). Regulation of copper transport in Arabidopsis thaliana: a biochemical oscillator? J Biol Inorg Chem. 15(1): 29-36. PubMed
2009
Puig S and Peñarrubia L (2009) Placing metal micronutrients in context: transport and distribution in plants.Curr. Opin. Plant Biol.. 12(3): 299-306. PubMed
2008
Perales L, Peñarrubia L, Cornejo MJ. (2008). Induction of a polyubiquitin gene promoter by dehydratation stresses in transformed rice cells. J. Plant Physiol. 165(2): 159-171. PubMed
2007
Puig S, Andrés- Colás N, García-Molina A and Peñarrubia L. (2007). Copper and iron homeostasis in Arabidopsis: responses to metal deficiencies, interactions and biotechnological applications. Plant Cell Environ. 30: 271-290. PubMed
Puig S, Mira H, Dorcey E, Sancenón V, Andrés-Colás N, García-Molina A, Burkhead JL, Gogolin KA, Abdel-Ghany SE, Thiele DJ, Ecker JR, Pilon M and Peñarrubia L. (2007). Higher plants possess two types of ATX1- like copper chaperones. Biochem. Biophys. Res. Com. 354: 385-390. PubMed
2006
Andrés-Colás N, Sancenon V, Rodriguez-Navarro S, Mayo S, Thiele DJ, Ecker JR, Puig S, Peñarrubia L. (2006). The Arabidopsis heavy metal P-type ATPase HMA5 interacts with metallochaperones and functions in copper detoxification of roots. Plant J. 45(2): 225-236. PubMed
2005
Abdel-Ghany SE, Burkhead JL, Gogolin KA, Andrés-Colás N, Bodecker JR, Puig S, Peñarrubia L, Pilon M. (2005). AtCCS is a functional homolog of the yeast copper chaperone Ccs1/Lys7. FEBS Lett. 579(11): 2307-2312. PubMed
2004
Sancenon V, Puig S, Mateu-Andres I, Dorcey E, Thiele DJ, Peñarrubia L. (2004). The Arabidopsis copper transporter COPT1 functions in root elongation and pollen development. J Biol Chem. 279(15): 15348-15355. PubMed
Mira H, Vilar M, Esteve V, Martinell M, Kogan MJ, Giralt E, Salom D, Mingarro I, Peñarrubia L, Perez-Paya E. (2004). Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper metallochaperone protein. BMC Struct Biol. 4: 7. PubMed
2003
Sancenon V, Puig S, Mira H, Thiele DJ, Peñarrubia L. (2003). Identification of a copper transporter family inArabidopsis thaliana.Plant Mol Biol. 51(4): 577-587. PubMed
2002
Mira H, Martinez N, Peñarrubia L. (2002). Expression of a vegetative- storage-protein gene from Arabidopsis is regulated by copper, senescence and ozone. Planta. 214(6): 939-946. PubMed
2001
Mira H, Martinez- Garcia F, Peñarrubia L. (2001). Evidence for the plant- specific intercellular transport of the Arabidopsis copper chaperone CCH. Plant J. 25(5): 521-528. PubMed
Mira H, Vilar M, Perez-Paya E, Peñarrubia L. (2001). Functional and conformational properties of the exclusive C-domain from the Arabidopsis copper chaperone (CCH). Biochem J. 357(Pt 2): 545-549. PubMed
1998
Himelblau E, Mira H, Lin SJ, Culotta VC, Peñarrubia L, Amasino RM. (1998). Identification of a functional homolog of the yeast copper homeostasis gene ATX1 from Arabidopsis. Plant Physiol. 117(4): 1227-1234. PubMed