In the study published by our research group in Experimental Physiology “Differential contribution of T-type voltage-gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits” we analysed the role of these channels in vascular contraction and, in the case of the renal artery, also in endothelium-dependent vasodilation. We have seen that their involvement increases when nitric oxide decreases, a common condition in cardiovascular diseases. The results suggest that T-type channels could become new therapeutic targets for improving vascular regulation and cardiovascular health.