Evolution & Health home
and Health Research Unit
Virus experimental evolution, virus social evolution, mutation rates, oncolytic viruses, phage
In our lab at the Science Park of the University of Valencia (find us), we study virus evolution from an experimental approach. Currently, we are investigating how social-like interactions shape the variability and evolution of viruses. We are also interested in exploring the use of viruses as anti-cancer therapeutic agents, and for phage therapy.
Rafael Sanjuán, Ph.D. in Evolutionary Genetics
Tel: +34 963 543 270
de Biología Integrativa de Sistemas (I2SysBio)
C/ Catedrático Agustín Escardino 9
46980 Paterna, Valencia
José M. Cuevas
José´s career has focused on the study of experimental and molecular evolution of viruses. After a 3-year postdoc granted by the Welcome Trust, he returned to the University of Valencia as a Juan de la Cierva postdoc to work on phage and VSV experimental evolution. After a stay at the Instituto de Biología Molecular y Celular de Plantas (IBMCP-CSIC) where he analyzed adaptive mechanisms of tobacco etch virus using microarrays and massive sequencing technologies, we returned to our group to study HIV variability, funded by the ERC and MINECO. He now has a Ramón y Cajal 5-year contract and runs his own project on the human plasma virome.
Pilar did her PhD in our lab and then moved to Strasbourg for a 4-year postdoc in which she investigated how adaptive immunity shapes the genetic diversity of polyomaviruses in renal transplant patients. She obtained a 3-year Juan de la Cierva senior postdoc contract in our laboratory and is currently contracted as a senior postdoc funded by the European Research Council (ERC)
did her PhD at the University of Sao Paulo on
the kinetics peroxiredoxin reduction by
ascorbate. She now has a postdoc funded by the European
Research Council (ERC) in which we aim
at characterizing the molecular basis
of saliva-driven virion aggregation in
vesicular stomatitis virus (VSV).
did a PhD in biomedicine at the University of
Barcelona and has joined us, funded by a MINECO
project, to work on oncolytic viruses. The aim
of his research is to use directed evolution to
improve the efficacy of an oncolytic VSV.
Juan Vicente Bou
Jenni has a Degree in Biotechnology and her PhD focuses on the origins of genetic diversity inhuman adenoviruses.
María has a PhD
on brain ultrastructure advised by Prof. José M.
García-Verdugo at the Universitat de València.
She joined our lab to analyse the structure of
viral infectious units.