The Gastrointestinal Infection Research Group of the Department of Microbiology and Ecology works in the Faculty of Medicine and Dentistry and is linked to the Clinical Microbiology Service of the Hospital Clínico Universitario de Valencia.
Our main objective is to investigate the pathogenic mechanisms of infectious agents that produce gastrointestinal pathology, mainly viruses (rotavirus and norovirus), as well as the immune response caused by these infections. Rotavirus and norovirus produce gastroenteritis that affect children, although noroviruses can also infect people of any age, often causing epidemic outbreaks. We study the immunological mechanisms of protection against these infections, as well as the molecular determinants that condition susceptibility to them.
- Study of the pathogenic mechanisms of rotavirus and norovirus.
- Study of the immune response to rotavirus and norovirus.
- Study of virus-host interactions.
- Study of virus / microbiota / host interactions
The aim of this line of research is to study the interactions that occur between enteric viruses and the host without excluding the interactions that occur between enteric viruses and the intestinal microbiota or the interaction between the intestinal microbiota and the host.
- Molecular epidemiology of rotavirus and norovirus infections
This line of research focuses on the study of the epidemiology of rotavirus and norovirus through the application of molecular techniques (RT-PCR, qPCR, cDNA sequencing, etc.) and the detection of new variants of viral genotypes.
- Pathogenesis and immune response of enteric virus infections: rotavirus and norovirus
The aim of this line of research is to study the pathogenic mechanisms and the immune response of infections by the two main enteric viruses (rotavirus and norovirus).
Burjassot/Paterna Campus
Av. Blasco Ibáñez, 15
46010 València (Valencia)
