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Analysis of FNdeltaRGD mice

Description

We want to find out what are the implications of removing the RGD sequence located in the 10th repeat of type III: 1) can a5ß1 integrins and av class bind to other regions of the FN or are they totally dependent on this sequence? can FN fibrillogenesis occur in the absence of this?

Keywords

fibronectin, integrins, embryonic development

Manager UV
  • Costell Rossello, M.mercedes
  • PDI-Catedratic/a d'Universitat
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Frascati classification