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Modulation of epithelial autophagy by macrophages: relevance to Crohn's disease and NSAID gastroenteropathy

Description

We study the mechanisms that regulate gastrointestinal mucosal recovery in chronic inflammatory pathologies (e.g. IBD), in particular how macrophages, cells of the innate immune system that accumulate in the mucosa of patients with this pathology, modulate these mechanisms.

Keywords

inflammation, barrier-epithelial function, Chron's disease, ulcerative colitis, innate immunity

Frascati classification