- ALEPUZ MARTINEZ, ELIA PAULAPDI-Catedratic/a d'Universitat
- Alepuz, P.M.; Cunningham, K. W.; Estruch, F. (1997) Glucose repression affects ion homeostasis in yeast through the regulation of the stress activated ENA1 gene. Molecular Microbiology , 26(1), pp. 91 - 99 . ISSN: 0950-382X
- de Alteriis, E., Alepuz, P.M., Estruch, F. and Parascandola, P (1997) Clues to the origin of high invertase activity in immobilized growing yeast: prolonged SUC2 transcription and less susceptibility of the enzyme to endogenous proteolysis. . Canadian Journal of Microbiology , 45(1), pp. 413 - 417 . ISSN: 0008-4166
- Alepuz, P. M., D. Matheos, K. Cunningham and F. Estruch (1999) The Saccharomyces cerevisiae RanGTP binding protein Msn5p is involved in different signal transduction pathways . Genetics , 153(3), pp. 1219 - 1231 . ISSN: 0016-6731
- Blondel, M., P. M. Alepuz, L. S. Huang, S. Shaham, G. Ammerer and M. Peter (1999) Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes & Development , 13(17), pp. 2284 - 2300 . ISSN: 0890-9369
- Alepuz, P. M., Jovanovic, A., Reiser, V. and Ammerer, G (2001) Stress induced MAP kinase Hog1 is part of transcription activation complexes. Molecular Cell , 7(17), pp. 767 - 777 . ISSN: 1097-2765
- de Nadal, E., Alepuz, P. M., and Posas, F (2002) Dealing with osmo-stress through MAP kinase activation. Embo Reports , 3(8), pp. 735 - 740 . ISSN: 1469-221X
- Alepuz, P. M., de Nadal, E., Zapater, M., Ammerer, G. and Posas, F., (2003) Osmostress induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA polymerase II. Embo Journal , 22(10), pp. 2433 - 2442 . ISSN: 0261-4189
- de Nadal, E., Zapater, M., Alepuz, P. M., Sumoy, L., Mas, G. and Posas, F (2004) Regulation of gene expression by the Hog1 MAPK is mediated by the Rpd3 histone deacetylase. Nature , 427, pp. 271 - 274 . ISSN: 0028-0836
- Jimeno-González, S., Gómez-Herreros, F., Alepuz, P. M. and Chávez, S., (2006) FACT requirement for transcription of yeast genes exhibiting nucleosomes positioned at the 5' end of their transcribed region. . Molecular and Cellular Biology , 26(23), pp. 8710 - 8721 . ISSN: 0270-7306
- Pérez-Ortín, J. E., Alepuz, P. M. and Moreno, J (2007) Genomics and gene transcription kinetics in yeast . Trends in Genetics , 23, pp. 250 - 257 . ISSN: 0168-9525
- Romero Santacreu, Lorena; Moreno Mariño, Joaquín; Pérez Ortín, José Enrique; Alepuz Martínez, Paula (2009) Specific and global regulation of mRNA stability during osmotic stress in Saccharomyces cerevisiae. RNA-A Publication of the Rna Society , 15(6), pp. 1110 - 1120 . ISSN: 1355-8382
- Romero-Santacreu, L., H. Orozco, E. Garre and P. Alepuz (2010) The bidirectional cytomegalovirus immediate/early promoter is regulated by Hog1 and the stress transcription factors Sko1 and Hot1 in yeast. Molecular Genetics and Genomics , 283(5), pp. 511 - 518 . ISSN: 1617-4615
- Garre, E.; Romero-Santacreu L; De Clercq, N.; Blasco-Angulo, N.; Sunnerhagen, P.; Alepuz P. (2012) Yeast mRNA cap-binding protein Cbc1/Sto1 is necessary for the rapid reprogramming of translation after hyperosmotic shock. Molecular Biology of the Cell , 23(1), pp. 137 - 150 . ISSN: 1059-1524
- Garre García, Elena; Romero Santacreu Lorena; Barneo-Muñoz, Manuela; Miguel, Ana; Pérez Ortín, José Enrique; Alepuz Martínez, Paula (2013) Nonsense-mediated mRNA decay controls the changes in yeast ribosomal protein pre-mRNAs levels upon osmotic stress. Plos One , 8(4), p. e61240 . ISSN: 1932-6203
- Miguel, A.; Montón, F.; Li, T.; Gómez-Herreros, G.; Chávez, S.; Alepuz, P. y Pérez-Ortín, J.E. (2013) External conditions inversely change the RNA polymerase II elongation rate and density in yeast. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1829, pp. 1248 - 1255 . ISSN: 1874-9399
- Pérez-Ortín, J.E., Alepuz, P.; Chávez, S. y Choder, M. (2013) Eukaryotic mRNA decay: methodologies, pathways, and links to other stages of gene expression. Journal of Molecular Biology , 425(20), pp. 3750 - 3775 . ISSN: 0022-2836
- Mercè Gomar-Alba; Paula Alepuz; Marcel·lí del Olmo (2013) Dissection of the elements of osmotic stress response transcription factor Hot1 involved in the interaction with MAPK kinase Hog1 and in the activation of transcription. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1829, pp. 1111 - 1125 . ISSN: 1874-9399
- Li, T.; Belda-Palazón, B.; Ferrando, A.; Alepuz, P (2014) Fertility and polarized cell growth depends on eIF5A for translation of polyproline-rich Formins in Saccharomyces cerevisiae. Genetics , 197(4), pp. 1191 - 1200 . ISSN: 0016-6731
- Canadell D, García-Martínez J, Alepuz P, Pérez-Ortín JE, Ariño J. (2015) Impact of high pH stress on yeast gene expression: A comprehensive analysis of mRNA turnover during stress responses. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1849(6), pp. 653 - 664 . ISSN: 1874-9399
- Aurora Zuzuarregui; Tianlu Li; Christina Friedmann; Gustav Ammerer; Paula Alepuz (2015) Msb2 is a Ste11 membrane concentrator required for full activation of the HOG pathway. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1849(6), pp. 722 - 730 . ISSN: 1874-9399
- Tianlu Li; Nikki De Clercq; Daniel A. Medina; Elena Garre; Per Sunnerhagen; José E. Pérez-Ortín; Paula Alepuz (2016) The mRNA cap-binding protein Cbc1 is required for high and timely expression of genes by promoting the accumulation of gene-specific activators at promoters. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1859, pp. 405 - 4119 . ISSN: 1874-9399
- van Wijlick L, Geissen R, Hilbig JS, Lagadec Q, Cantero PD, Pfeifer E, Juchimiuk M, Kluge S, Wickert S, Alepuz P, Ernst JF (2016) Dom34 Links Translation to Protein O-mannosylation. Plos Genetics , 12(10), p. e1006395 . ISSN: 1553-7390
- Ballester-Tomás L; Prieto JA; Alepuz P; González A; Garre E; Randez-Gil F (2017) Inappropriate translation inhibition and P-body formation causes cold-sensitivity in tryptophan-auxotroph yeast mutants. Biochimica et Biophysica Acta-Molecular Cell Research , 1864(2), pp. 314 - 323 . ISSN: 0167-4889
- Benet M, Miguel A, Carrasco F, Li T, Planells J, Alepuz P, Tordera V, Pérez-Ortín JE. (2017) Modulation of protein synthesis and degradation maintains proteostasis during yeast growth at different temperatures. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1860, pp. 794 - 802 . ISSN: 1874-9399
- Pelechano V; Alepuz P (2017) eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences. Nucleic Acids Research , 45(12), pp. 7326 - 7338 . ISSN: 0305-1048
- MUÑOZ-SORIANO V.; LI T.; DOMINGO-MUELAS A.; GAMERO E.; BIZY A.; FARIÑAS I.; ALEPUZ P.; PARICIO N. (2017) Evolutionary conserved role of eukaryotic translation factor eIF5A in the regulation of actin-nucleating formins. Scientific Reports , 7(1), p. 9580 . ISSN: 2045-2322
- Ramos-Alonso L; Romero AM; Soler MÀ; Perea-García A; Alepuz P; Puig S; Martínez-Pastor MT. (2018) Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency. PLOS genetics , 14(6), p. e1007476 . ISSN: 1553-7390
- Desai PR; Lengeler K; Kapitan M; Janßen SM; Alepuz P; Jacobsen ID; Ernst JF. (2018) The 5' Untranslated Region of the EFG1 Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in Candida albicans. Msphere , 3(4), p. e00280-18 . ISSN: 2379-5042
- Garre E; Pelechano V; Sánchez Del Pino M; Alepuz P; Sunnerhagen P. (2018) The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock. Plos Genetics , 14(7), p. e1007563 . ISSN: 1553-7390
- Quilis, I.; Taberner, F.J.; Martínez-Garay, C.A.; Alepuz, P.; Igual, J.C. (2019) Karyopherin Msn5 is involved in a novel mechanism controlling the cellular level of cell cycle regulators Cln2 and Swi5. Cell Cycle , 18(5), pp. 580 - 595 . ISSN: 1538-4101
- Pérez-Martínez ME, Benet M, Alepuz P, Tordera V. (2019) Nut1/Hos1 and Sas2/Rpd3 control the H3 acetylation of two different sets of osmotic stress-induced genes. Epigenetics , 15(3), pp. 251 - 271 . ISSN: 1559-2294
- Romero AM; Ramos-Alonso L; Alepuz P; Puig S; Martínez-Pastor MT (2020) Global translational repression induced by iron deficiency in yeast depends on the Gcn2/eIF2α pathway. Scientific Reports , 10(1), p. 233 . ISSN: 2045-2322
- Rosa-Téllez, S., Kanhonou R., Castellote-Bellés, C., Serrano, R., Alepuz, P., Ros, R. (2020) RNA-Binding Proteins as Targets to Improve Salt Stress Tolerance in Crops. Agronomy-Basel , 10(250) . ISSN: 2073-4395
- Barba-Aliaga M; Villarroel-Vicente C; Stanciu A; Corman A; Martínez-Pastor MT; Alepuz P. (2021) Yeast translation elongation factor eIF5A expression is regulated by nutrient availability through different signalling pathways. International Journal Of Molecular Sciences , 22(219) . ISSN: 1661-6596
- José García-Martínez; María E Pérez-Martínez; José E Pérez-Ortín; Paula Alepuz (2021) Recruitment of Xrn1 to stress-induced genes allows efficient transcription by controlling RNA polymerase II backtracking. Rna Biology , 18(10), pp. 1458 - 1474 . ISSN: 1547-6286
- Begley V; Jordán-Pla A; Peñate X; Garrido-Godino AI; Challal D; Cuevas-Bermúdez A; Mitjavila A; Barucco M; Gutiérrez G; Singh A; Alepuz P; Navarro F; Libri D; Pérez-Ortín JE; Chávez S. (2021) Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration. Rna Biology , 18(9), pp. 1310 - 1323 . ISSN: 1547-6286
- Barba-Aliaga M.; Alepuz P.; Pérez-Ortín J.E. (2021) Eukaryotic RNA Polymerases: the many ways to transcribe a gene. Frontiers In Molecular Biosciences , 8(663209) . ISSN: 2296-889X
- Barba-Aliaga M; Mena A; Espinoza V; Apostolova N; Costell M; Alepuz P. (2021) Hypusinated eIF5A is required for the translation of collagen. Journal of Cell Science , 134(18), pp. jcs258643-1 - 21 . ISSN: 0021-9533
- Marina Barba-Aliaga; Paula Alepuz (2022) Role of eIF5A in Mitochondrial Function. International Journal Of Molecular Sciences , 23(3), p. 1284 . ISSN: 1661-6596
- Marina Barba-Aliaga M; Paula Alepuz (2022) The activator/repressor Hap1 binds to the yeast eIF5A-encoding gene TIF51A to adapt its expression to the mitochondrial functional status. Febs Letters , 596((14)), pp. 1809 - 1818 . ISSN: 0014-5793
- Tania Jordá; Marina Barba-Aliaga; Nicolas Rozès; Paula Alepuz; María Teresa Martínez-Pastor; Sergi Puig (2022) Transcriptional regulation of Ergosterol biosynthesis genes in response to iron deficiency. Environmental Microbiology . ISSN: 1462-2912
- Yu Xiao; Jia Li, Ruanlin Wang; Yajiao Fan; Xiaxia Han; Yuejun Fu; Paula Alepuz; Wei Wang; Aihua Liang (2023) eIF5A promotes +1 programmed ribosomal frameshifting in Euplotes octocarinatus. International Journal of Biological Macromolecules , 254, p. 127743 . ISSN: 0141-8130
- Rosa-Téllez, S., Alcántara-Enguídanos, A., Martínez-Seidel, F., Casatejada-Anchel, R., Saeheng, S., Bailes, C. L., Erban, A., Barbosa-Medeiros, D., Alepúz, Paula., Matus, J.T. Kopka, J., Muñoz-Bertomeu,J., Krueger, S., Roje, S., Fernie, A.R., Ros, R (2024) The Serine-Glycine-One-Carbon metabolic network orchestrates changes in nitrogen and sulfur metabolism and shapes plant development. Plant Cell , 36, pp. 404 - 426 . ISSN: 1040-4651
- Rocío Seoane; Tomás Lama‑Díaz; Antonia María Romero; Ahmed El Motiam; Arantxa Martínez‑Férriz; Santiago Vidal; Yanis H. Bouzaher; María Blanquer; Rocío M. Tolosa; Juan Castillo Mewa; Manuel S. Rodríguez; Adolfo García‑Sastre; Dimitris Xirodimas; James D. Sutherland; Rosa Barrio; Paula Alepuz; Miguel G. Blanco; Rosa Farràs; Carmen Rivas (2024) SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells. Cellular and Molecular Biology Letters , 29(1), p. 15 . ISSN: 1689-1392
- Marina Barba-Aliaga; Vanessa Bernal; Cynthia Rong; Madeleine Volfbeyn; Keguang Zhang; Brian Zid; Paula Alepuz (2024) eIF5A controls mitoprotein import by relieving ribosome stalling at TIM50 translocase mRNA. Journal of Cell Biology . ISSN: 0021-9525
Publicaciones en revistas
- Elena Garre, Paula Alepuz, Per Sunnerhagen, (2018). Exploring how an RNA-binding protein affects stress-exposed cells. . . (pp. 1 - 3). .
Otras Publicaciones
- PEREZ ORTIN, JOSE ENRIQUEPDI-Catedratic/a d'Universitat+Coordinador/a de Programa de Doctorat+Secretari/a d' Institut Universitari
- Igual, J.C.; Matallana, E.; González-Bosch, C.; Franco, L.; Pérez-Ortín, J.E. (1991) A new glucose-repressible gene identified from the analysis of chromatin structure of deletion mutants of the yeast SUC2 locus. Yeast , 7, pp. 379 - 389 . ISSN: 1097-0061
- Matallana, E.; Franco, L. y Pérez-Ortín, J.E. (1992) Chromatin structure of the yeast SUC2 promoter in regulatory mutants. Molecular and General Genetics , 231, pp. 395 - 400 . ISSN: 0026-8925
- Igual, J.C.; González-Bosch, C; Dopazo, J.; Pérez-Ortín, J.E. (1992) Phylogenetic analysis of the thiolase family. Implications on the evolutionary origin of peroxisomes. Journal of Molecular Evolution , 35, pp. 147 - 155 . ISSN: 0022-2844
- Igual, J.C.; González-Bosch, C.; Franco, L.; Pérez-Ortín, J.E. (1992) The POT1 gene for the yeast peroxisomal thiolase is subjected to three different mechanisms of regulation. Molecular Microbiology , 6, pp. 1867 - 1875 . ISSN: 0950-382X
- Del Olmo M. y Pérez-Ortín, J.E. (1993) A natural A/T-rich sequence from the 3' end of yeast FBP1 gene exists as a cruciform in E. coli cells. Plasmid , 29, pp. 222 - 232 . ISSN: 0147-619X
- Tordera, V., Sendra, R. y Pérez-Ortín, J.E. (1993) The role of histones and their modifications in informative content of chromatin. Experientia , 49, pp. 780 - 788 . ISSN: 0014-4754
- Del Olmo, M.; Sogo, J.M.; Franco, L. y Pérez-Ortín, J.E. (1993) Chromatin structure of the yeast FBP1 gene: transcription-dependent changes in the regulatory and coding regions. Yeast , 9, pp. 1229 - 1240 . ISSN: 1097-0061
- Bargues, M.; Salom, D.; Gómez, A.; Paricio, N.; Pérez-Alonso, M. y Pérez-Ortín, J.E. (1996) Sequencing analysis of a 4.1 kb subtelomeric region from yeast chromosome IV identifies HXT15, a new member of the hexose transporter family. Yeast , 12, pp. 1005 - 1011 . ISSN: 1097-0061
- Puig, S.; Querol, A.; Ramón, D. y Pérez-Ortín, J.E. (1996) Evaluation of the use of late phase gene promoters for the expression of enological enzymes in an industrial wine yeast strain. Biotechnology Letters , 18, pp. 887 - 892 . ISSN: 0141-5492
- Jacq, C...Pérez-Ortín, J.E. et al. (1997) The complete nucleotide sequence of yeast chromosome IV. Nature , 387 (suplement), pp. 75 - 78 . ISSN: 0028-0836
- Aranda, A.; Pérez-Ortín, J.E.; Benham, C.J. y del Olmo, M. (1997) Analysis of the in vivo structure of a natural alternating d(TA)n sequence in yeast chromatin. Yeast , 13, pp. 313 - 326 . ISSN: 1097-0061
- Puig, S., Ramón D. y Pérez-Ortín, J. E. (1998) An optimized method to obtain stable food-safe recombinant wine yeast strains. Journal of Agricultural and Food Chemistry , 46, pp. 1689 - 1693 . ISSN: 0021-8561
- Aranda, A.; Pérez-Ortín, J.E.; Moore, C. y del Olmo, M. (1998) Transcription termination downstream of the Saccharomyces cerevisiae FBP1 poly(A) site does not depend on efficient 3' end processing. RNA-A Publication of the Rna Society , 4(3), pp. 303 - 318 . ISSN: 1355-8382
- Ruiz-García, A.B.; Sendra, R.; Galiana, M.; Pamblanco, M.; Pérez-Ortín, J.E. y Tordera., V. (1998) HAT1 and HAT2 proteins are componets of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4. Journal of Biological Chemistry , 273, pp. 12599 - 12605 . ISSN: 0021-9258
- Aranda, A.; Pérez-Ortín, J.E.; Moore, C. y del Olmo, M. (1998) The yeast FBP1 poly(A) signal functions in both orientations and overlaps with a gene promoter. Nucleic Acids Research , 26(20), pp. 4588 - 4596 . ISSN: 0305-1048
- Gimeno-Alcañiz, J.; Pérez-Ortín, J.E. y Matallana, E. (1999) Differential patterns of threalose accumulation in wine yeast strains during microvinification process. Biotechnology Letters , 21, pp. 271 - 274 . ISSN: 0141-5492
- Ivorra, C.; Pérez-Ortín, J.E.y del Olmo, M. (1999) Reverse correlation of stress-resistance ability and stuck fermentations in wine yeasts. A molecular study. Biotechnology and Bioengineering , 64(6), pp. 698 - 708 . ISSN: 0006-3592
- Rodriguez-Navarro, S.; Estruch, F. y Pérez-Ortín, J.E. (1999) Functional analysis of twelve ORFs from Saccharomyces cerevisiae. Yeast , 15, pp. 913 - 919 . ISSN: 1097-0061
- Puig, S.; Matallana, E. y Pérez-Ortín, J.E (1999) Stochastical nucleosome positioning in a yeast chromatin region is not dependent on Histone H1. Current Microbiology , 39, pp. 168 - 172 . ISSN: 0343-8651
- Puig, S.; Pérez-Ortín, J.E y Matallana, E. (1999) Transcriptional and structural study of a region of two convergent overlapping yeast genes. Current Microbiology , 39, pp. 369 - 373 . ISSN: 0343-8651
- Puig, S.y Pérez-Ortín, J.E. (2000) Stress response and expression patterns in wine fermentation of yeast genes induced at the diauxic shift. Yeast , 16, pp. 139 - 148 . ISSN: 1097-0061
- van Helden, J.; Olmo Muñoz, Marcel·lí del; Pérez Ortín, José Enrique (2000) Statistical analysis of yeast genomic downstream sequences reveals putative polyadenylation signals. Nucleic Acids Research , 28(4), pp. 1000 - 1010 . ISSN: 0305-1048
- Puig Todolí, Sergi; Querol Simón, Amparo; Barrio Esparducer, Eladio; Pérez Ortín, José Enrique (2000) Mitotic recombination and genetic changes in Saccharomyces cerevisiae during wine fermentation. Applied and Environmental Microbiology , 66(5), pp. 2057 - 2061 . ISSN: 0099-2240
- Puig, S. y Pérez-Ortín, J.E. (2000) Expression levels and pattern of glycolytic yeast genes during wine fermentation. Systematic and Applied Microbiology , 23, pp. 300 - 303 . ISSN: 0723-2020
- Hauser, N.C.; Fellenberg, K.; Gil, R., Bastuck, S.; Hoheisel, J.D.; Pérez Ortín, José Enrique (2001) Whole genome analysis of a wine yeast strain. Comparative And Functional Genomics , 2(2), pp. 69 - 79 . ISSN: 1531-6912
- PAMBLANCO, M.; POVEDA, A.; SENDRA, R.; RODRÍGUEZ-NAVARRO, S.; PÉREZ-ORTÍN, J. E.; TORDERA, V. (2001) Bromodomain factor 1 (Bdf1) protein interacts with histones. Febs Letters , 496, pp. 31 - 35 . ISSN: 0014-5793
- Rodríguez-Navarro, S.; Igual, J.C.; Pérez-Ortín, J.E. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast , 19, pp. 43 - 54 . ISSN: 1097-0061
- Pérez-Ortín, J.E.; García-Martínez, J. and Alberola T. M. (2002) DNA chips for yeast biotechnology. The case of wine yeasts. Journal of Biotechnology , 98, pp. 227 - 241 . ISSN: 0168-1656
- Pérez-Torrado, R., Carrasco, P., Aranda, A., Gimeno-Alcañiz, J., Pérez-Ortín, J.E., Matallana, E, y Del Olmo, M. (2002) Study of the first hours of vinification by the use of osmotic stress-specific response genes as probes. Systematic and Applied Microbiology , 25(1), pp. 153 - 161 . ISSN: 0723-2020
- Rodríguez-Navarro, Susana; Llorente, B.; Rodríguez-Manzaneque, M.T.; Ramne, A.; Uber Garcia, Genoveva; Marchesan, D.; Dujon, B.; Herrero,E.; Sunnerhagen, P.; Pérez-Ortín, José Enrique (2002) Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6. Yeast , 19, pp. 1261 - 1276 . ISSN: 1097-0061
- Pérez Ortín, José Enrique; Querol Simón, Amparo; Puig Todolí, Sergi; Barrio Esparducer, Eladio (2002) Molecular characterization of a chromosomal rearrangement involved in the adaptative evolution of yeast strains. Genome Research , 12(10), pp. 1533 - 1539 . ISSN: 1088-9051
- Carrasco, P.; Pérez-Ortín, J.E. y del Olmo, M. (2003) Arginase Activity is a Useful Marker of Growth Nitrogen Limitation During Wine Fermentations. Systematic and Applied Microbiology , 26, pp. 471 - 479 . ISSN: 0723-2020
- Rodríguez-Navarro, Susana; Fischer, Tomás; Luo, Ming Juan; Antúnez, Oreto; Brettschneider, Susanne; Pérez Ortín, José Enrique; Reed, Robin; Hurt, Ed (2004) SUS1, a functional component of the SAGA transcription complex and the mRNA export machinery. Cell , 116(1), pp. 75 - 86 . ISSN: 0092-8674
- Bellí, G.; Molina, M.M.; García Martínez, José; Pérez-Ortín, José Enrique; Herrero, Enrique (2004) Saccharomyces cerevisiae glutaredoxin 5-deficient cells subjected to constitutive oxidizing conditions are affected in the expression of specific sets of genes. Journal of Biological Chemistry , 279(13), pp. 12386 - 12395 . ISSN: 0021-9258
- Alberola, T. M., García-Martínez, J., Antúnez, O., Viladevall, L., Barceló, A., Ariño, J. y Pérez-Ortín, J.E. (2004) A new set of DNA macrochips for the yeast Saccharomyces cerevisiae: features and uses. International Microbiology , 7(3), pp. 199 - 206 . ISSN: 1139-6709
- Pérez-Ortín, J.E.; del Olmo, M.; Matallana, E. y Tordera, V. (1997) Make your own gene library. Biochemical Education , 25, pp. 237 - 242 . ISSN: 0307-4412
- Del OLMO, M.; ARANDA, A.; TORDERA, V.; PÉREZ-ORTÍN, J.E. (1998) Detection of non-B-DNA secondary structures by S1 nuclease digestion. Journal of Chemical Education , 75, pp. 762 - 765 . ISSN: 0021-9584
- Pérez-Ortín, J.E. ; Moya, A. y Ramón, D. (1998) Els altres genomes. Mètode - Revista de la Universitat de València , 32, pp. 57 - 60 . ISSN: 1133-3987
- Carro, D.; García-Martínez, J; Pérez-Ortín, J.E. y Piña, B. (2003) Structural characterization of chromosome I size variants from a natural yeast strain. Yeast , 20, pp. 171 - 180 . ISSN: 1097-0061
- Güldener, U; Münsterkötter, M.; Kastenmüller, G; Strack1, N; van Helden, J.; Lemer, C.; Richelles, J.; Wodak, S.J.; García Martínez, José; Pérez Ortín, José E.; Michael, H.; Kaps, A.; Talla, E.; Dujon, B.; André, B.; Souciet, J.L.; De Montigny, J.; Bon, E.; Gaillardin, C. y Mewes, H.W (2005) CYGD: The Comprehensive Yeast Genome Database. Nucleic Acids Research , 33(suppl 1), pp. D364 - D368 . ISSN: 0305-1048
- Pérez-Ortín, J.E. y García-Martínez, J. (2004) Evaluation of transcription rates at the genomic level. Bioforum Europe , 8(5), pp. 46 - 48 . ISSN: 1611-597X
- Garcia Martinez, José; Aranda Fernández, Agustín; Pérez Ortín, José Enrique (2004) Genomic run-on evaluates transcription rates for all yeast genes and identifies gene regulatory mechanisms. Molecular Cell , 15(2), pp. 303 - 313 . ISSN: 1097-2765
- Rosaleny Peralvo, Lorena Estefania; Antúnez, O.; Ruiz Garcia, Ana Belén; Pérez Ortin, José Enriqu.; Tordera Donderis, Vicente (2005) Yeast HAT1 and HAT2 deletions have different life-span and transcriptome phenotypes. Febs Letters , 579(19), pp. 4063 - 4068 . ISSN: 0014-5793
- Solieri, L.; Gullo, M.; De Vero, L.; Antúnez, O.; Pérez Ortín, José Enrique; Giudici, P. (2005) Homogeneity of Interspecific Hybrids Between Saccharomyces cerevisiae and Saccharomyces uvarum by Phenotypic and Transcriptional Analysis. International Journal of Biotechnology & Biochemistry (IJBB) , 1(1), pp. 11 - 21 . ISSN: 0973-2691
- Pelechano, Vicente José; García Martínez, José; Pérez Ortín, José Enrique (2006) A genomic study of the Inter-ORF distances in Saccharomyces cerevisiae. Yeast , 23, pp. 689 - 699 . ISSN: 1097-0061
- Mendes-Ferreira A.; Olmo Muñoz, Marcel·lí del; García Martínez José; Jiménez Martí Elena; Mendes-Faia A.; Pérez Ortín, José Enrique; Leão C. (2007) Transcriptional response of Saccharomyces cerevisiae to different nitrogen concentrations during alcoholic fermentation. Applied and Environmental Microbiology , 73(9), pp. 3049 - 3060 . ISSN: 0099-2240
- Pérez Ortín, José Enrique; Alepuz Martínez, Paula; Moreno Mariño, Joaquín (2007) Genomics and the gene transcription kinetics in yeast. Trends in Genetics , 23(5), pp. 250 - 257 . ISSN: 0168-9525
- Rosaleny Peralvo, Lorena Estefanía; Ruiz García, Ana Belén; García Martínez, José; Pérez Ortín, José Enrique; Tordera Donderis, Vicente (2007) The Sas3p and Gcn5p histone acetyltransferases are recruited to similar genes. Genome biology , 8(6), p. R119 . ISSN: 1474-7596
- Mendes-Ferreira A.; Olmo Muñoz, Marcel·li del; García Martínez José; Jiménez Martí, Elena; Leão, C.; Mendes-Faia A, Pérez Ortín José E. (2007) Saccharomyces cerevisiae signature genes for predicting nitrogen deficiency during alcoholic fermentation. Applied and Environmental Microbiology , 73(16), pp. 5363 - 5369 . ISSN: 0099-2240
- Pelechano García, Vicente José; Pérez Ortín, José Enrique (2007) The transcriptional inhibitor thiolutin blocks mRNA degradation. Yeast , 25(2), pp. 85 - 92 . ISSN: 1097-0061
- García Martínez, José; González Candelas, Fernando; Pérez Ortín, José Enrique (2007) Common gene expression strategies revealed by genome-wide analysis in yeast. Genome biology , 8, p. R222 . ISSN: 1474-7596
- Pérez Ortín, José Enrique (2007) Genomics of mRNA turnover. Briefings in Functional Genomics & Proteomics , 6(4), pp. 282 - 291 . ISSN: 1473-9550
- Fernando Cardona, Purificación Carrasco, José Enrique Pérez-Ortín, Marcel.lí del Olmo*, Agustín Aranda (* corresponding author) (2007) A novel approach for the improvement of stress resistance in wine yeasts. International Journal of Food Microbiology , 114(1), pp. 83 - 91 . ISSN: 0168-1605
- Molina-Navarro, M.M.; Castells-Roca, L.; Bellí, G.; García-Martínez, J.; Marín-Navarro, J.; Moreno, J. Pérez-Ortín, J.E. y Herrero, E. (2008) Comprehensive transcriptional analysis of the oxidative response in yeast. Journal of Biological Chemistry , 283, pp. 17908 - 17918 . ISSN: 0021-9258
- Solieri, L.; Antúnez, O.; Pérez-Ortín, J.E.; Barrio, E. y Giudici, P (2008) Mitochondria inheritance and fermentative/oxidative balance in hybrids between Saccharomyces cerevisiae and Saccharomyces uvarum. Yeast , 25(7), pp. 485 - 500 . ISSN: 1097-0061
- Grund, S.E.; Fischer, T.; Cabal, G.G.; Antúnez, O.; Pérez Ortín, José Enrique; Hurt, E. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. Journal of Cell Biology , 182(5), pp. 897 - 910 . ISSN: 0021-9525
- Belloch, Carmela; Pérez Torrado, Roberto; González, Sara S.; Pérez Ortín, José Enrique; García Martínez, José; Querol Simón, Amparo; Barrio Esparducer, Eladio (2009) Chimeric Genomes of Natural Hybrids of Saccharomyces cerevisiae and Saccharomyces kudriavzevii. Applied and Environmental Microbiology , 75(8), pp. 2534 - 2544 . ISSN: 0099-2240
- Pelechano García, Vicente José; Jimeno-González, Silvia; Rodríguez-Gil, Alfonso; García Martínez, José; Pérez Ortín, José Enrique; Chávez, Sebastián (2009) Regulon-specific control of transcription elongation across the yeast genome. PLOS genetics , 5(8), p. e1000614 . ISSN: 1553-7390
- Romero Santacreu, Lorena; Moreno Mariño, Joaquín; Pérez Ortín, José Enrique; Alepuz Martínez, Paula (2009) Specific and global regulation of mRNA stability during osmotic stress in Saccharomyces cerevisiae. RNA-A Publication of the Rna Society , 15(6), pp. 1110 - 1120 . ISSN: 1355-8382
- Pelechano García, Vicente José; Pérez Ortín, José Enrique (2010) There is a steady-state transcriptome in exponentially growing yeast cells. Yeast , 27(7), pp. 413 - 422 . ISSN: 1097-0061
- Rodríguez-Gil, Alfonso; García Martínez, José; Pelechano García, Vicente José; Muñoz-Centeno, María de la Cruz; Geli, Vincent; Pérez Ortín, José Enrique; Chávez, Sebastián (2010) The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors. Nucleic Acids Research , 38(14), pp. 4651 - 4664 . ISSN: 0305-1048
- Bermúdez, Ignacio; García Martínez, José; Pérez Ortín, José Enrique; Roca, Joaquim (2010) A method for genome-wide analysis of DNA helical tension by means of psoralen-DNA photobinding. Nucleic Acids Research , 38(19), p. e182 . ISSN: 0305-1048
- Pelechano García, Vicente José; Chávez, Sebastián; Pérez Ortín, José Enrique (2010) A complete set of nascent transcription rates for yeast genes. Plos One , 5(11), p. e15442 . ISSN: 1932-6203
- Castells-Roca, L.; García-Martínez, J.; Moreno Mariño, Joaquín; Herrero, E.; Bellí, G. y Pérez Ortín, José Enrique (2011) Heat shock response in yeast involver changes in both transcription rates and mRNA stabilities. Plos One , 6(2), p. e17272 . ISSN: 1932-6203
- Pérez Ortín, José Enrique; Jordán Pla, Antonio; Pelechano García, Vicente José (2011) A genomic view of mRNA turnover in yeast. Comptes Rendus Biologies , 334(8-9), pp. 647 - 654 . ISSN: 1631-0691
- Vicente Tordera y José E. Pérez Ortín (2011) Hipótesis y dogmas. Investigación y Ciencia , 2011(Agosto), pp. 3 - 3 . ISSN: 0210-136X
- Pérez Ortín, José Enrique; Medina, Daniel A; Jordán Plá, Antonio (2011) Genomic insights into the layers of gene regulation in yeast. Genetics Research International , 2011(989303) . ISSN: 2090-3154
- M. Carmen García-López, Vicent Pelechano, M. Carmen Mirón-García, Ana I. Garrido-Godino,Alicia García, Olga Calvo, Michel Werner, José E. Pérez-Ortín, and Francisco Navarro (2011) The conserved foot domain of RNA Pol II associates with proteins involved in transcritpion initiation and/or early elongation. Genetics , 189, pp. 1235 - 1248 . ISSN: 0016-6731
- García Martínez, José; Ayala Gallego, Guillermo; Pelechano García, Vicente José; Chávez, S.; Herrero, E.; Pérez Ortín, José Enrique (2012) The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast. Transcription , 3(1), pp. 39 - 44 . ISSN: 2154-1264
- Pérez Ortín, José Enrique; De Miguel-Jiménez, Lola; Chávez, Sebastián (2012) Genome-wide studies of mRNA synthesis and degradation in eukaryotes. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1819(6), pp. 604 - 615 . ISSN: 1874-9399
- Alic, Andrei; Pérez Ortín, José Enrique; Moreno Mariño, Joaquín.; Arnau LLombart, Vicente (2013) mRNAstab. A web application for mRNA stability analysis. Bioinformatics , 29, pp. 813 - 814 . ISSN: 1367-4803
- Garre García, Elena; Romero Santacreu Lorena; Barneo-Muñoz, Manuela; Miguel, Ana; Pérez Ortín, José Enrique; Alepuz Martínez, Paula (2013) Nonsense-mediated mRNA decay controls the changes in yeast ribosomal protein pre-mRNAs levels upon osmotic stress. Plos One , 8(4), p. e61240 . ISSN: 1932-6203
- José E. Pérez-Ortín, Paula Alepuz, Sebastián Chávez and Mordechai Choder (2013) Eukaryotic mRNA Decay: Methodologies, Pathways, and Links to Other Stages of Gene Expression. Journal of Molecular Biology , S0022-2836(13), pp. 00131 - 00139 . ISSN: 0022-2836
- Haimovich, G.; Medina, D.A.; Causse, S.Z.; Garber, M.; Millán-Zambrano, G.; Barkai, O.; Chávez, S.; Pérez Ortín, José Enrique; Darzacq, X.; Choder, M. (2013) Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis. Cell , 153(5), pp. 1000 - 1011 . ISSN: 0092-8674
- Nikolaou, C.; Bermúdez, I.; Manichanh, C.; García-Martínez, José; Guigó, R.; Pérez-Ortín, José E.; Roca, J. (2013) Topoisomerase II regulates yeast genes with singular chromatin architectures. Nucleic Acids Research , 41(20), pp. 9243 - 9256 . ISSN: 0305-1048
- Miguel, A.; Montón, F.; Li, T.; Gómez-Herreros, G.; Chávez, S.; Alepuz, P. y Pérez-Ortín, J.E. (2013) External conditions inversely change the RNA polymerase II elongation rate and density in yeast. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1829, pp. 1248 - 1255 . ISSN: 1874-9399
- Pérez-Ortín, J.E., Alepuz, P.; Chávez, S. y Choder, M. (2013) Eukaryotic mRNA decay: methodologies, pathways, and links to other stages of gene expression. Journal of Molecular Biology , 425(20), pp. 3750 - 3775 . ISSN: 0022-2836
- José E. Pérez-Ortín, Daniel A. Medina, Sebastián Chavez y Joaquín Moreno (2013) What do you mean by transcription rate?. Bioessays , 35, pp. 1056 - 1062 . ISSN: 0265-9247
- Medina, DA; Jordán-Pla, A.; Millán-Zambrano, G.; Chávez, S.; Choder, M.; Pérez Ortín, José Enrique (2014) Cytoplasmic 5'-3' exonuclease Xrn1p is also a genome-wide transcription factor in yeast. Frontiers In Genetics , 5(1) . ISSN: 1664-8021
- Jordán-Pla, A.; Gupta, I.; de Miguel-Jiménez, L.; Steinmetz, L.M.; Chávez, S.; Pelechano V. y Pérez-Ortín, J.E. (2015) Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle. Nucleic Acids Research , 43(2), pp. 787 - 802 . ISSN: 0305-1048
- Barbosa C, García-Martínez J, Pérez-Ortín JE, Mendes-Ferreira A. (2015) Comparative Transcriptomic Analysis Reveals Similarities and Dissimilarities in Saccharomyces cerevisiae Wine Strains Response to Nitrogen Availability. Plos One , 10(4), p. e0122709 . ISSN: 1932-6203
- Canadell D, García-Martínez J, Alepuz P, Pérez-Ortín JE, Ariño J. (2015) Impact of high pH stress on yeast gene expression: A comprehensive analysis of mRNA turnover during stress responses. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1849(6), pp. 653 - 664 . ISSN: 1874-9399
- Juanes JM, Miguel A, Morales LJ, Pérez-Ortín JE, Arnau V (2015) A web application for the unspecific detection of differentially expressed DNA regions in strand-specific expression data. Bioinformatics , 31(19), pp. 3228 - 3230 . ISSN: 1367-4803
- Natalia Gómez-Navarro, Antonio Jordán-Pla, Francisco Estruch y José E. Pérez-Ortín (2016) Defects in the NC2 repressor affect both canonical and non-coding RNA polymerase II transcription initiation in yeast. Bmc Genomics , 17, pp. 183-1 - 183-9 . ISSN: 1471-2164
- Tianlu Li; Nikki De Clercq; Daniel A. Medina; Elena Garre; Per Sunnerhagen; José E. Pérez-Ortín; Paula Alepuz (2016) The mRNA cap-binding protein Cbc1 is required for high and timely expression of genes by promoting the accumulation of gene-specific activators at promoters. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1859, pp. 405 - 4119 . ISSN: 1874-9399
- García-Martínez, José; Delgado-Ramos, Lidia; Ayala, Guillermo; Pelechano, Vicent; Medina, Daniel A.; Carrasco, Fany; González, Ramón; Andrés-León, Eduardo; Steinmetz, Lars; Warringer, Jonas; Chávez, Sebastián; Pérez-Ortín, José E (2016) The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons. Nucleic Acids Research , 44, pp. 3643 - 3658 . ISSN: 0305-1048
- Garrido-Godino AI; García-López MC; García-Martínez J; Pelechano V; Medina DA; Pérez-Ortín JE; Navarro F. (2016) Rpb1 foot mutations demonstrate a major role of Rpb4 in mRNA stability during stress situations in yeast. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1859(5), pp. 731 - 743 . ISSN: 1874-9399
- Sebastián Chávez; José García-Martínez;· Lidia Delgado-Ramos; José E. Pérez-Ortín (2016) The Importance of controlling mRNA turnover during cell proliferation. Current Genetics , 62(4), pp. 701 - 710 . ISSN: 0172-8083
- José García-Martínez; Kevin Troulé; Sebastián Chávez; José E. Pérez-Ortín (2016) Growth Rate controls mRNA turnover in steady and non-steady states. Rna Biology , 13(12), pp. 1175 - 1181 . ISSN: 1547-6286
- Benet M, Miguel A, Carrasco F, Li T, Planells J, Alepuz P, Tordera V, Pérez-Ortín JE. (2017) Modulation of protein synthesis and degradation maintains proteostasis during yeast growth at different temperatures. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1860, pp. 794 - 802 . ISSN: 1874-9399
- Adriana Mena, Daniel A. Medina, José García-Martínez, Victoria Begley, Abhyudai Singh, Sebastián Chávez, Mari C. Muñoz-Centeno, José E. Pérez-Ortín (2017) Asymmetric cell division requires specific mechanisms for adjusting global transcription. Nucleic Acids Research , 45(21), pp. 12401 - 12412 . ISSN: 0305-1048
- Gabriel Gutiérrez; Gonzalo Millán-Zambrano; Daniel A. Medina; Antonio Jordán-Pla; José E. Pérez-Ortín; Xenia Peñate; Sebastián Chávez (2017) Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning. Epigenetics & Chromatin , 10(58), pp. 1 - 22 . ISSN: 1756-8935
- Varinia García‑Molinero, José García‑Martínez, Rohit Reja, Pedro Furió‑Tarí, Oreto Antúnez, Vinesh Vinayachandran, Ana Conesa, B. Franklin Pugh, José E. Pérez‑Ortín, Susana Rodríguez‑Navarro (2018) The SAGA/TREX‑2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally. Epigenetics & Chromatin , 11(13), pp. 1 - 12 . ISSN: 1756-8935
- Fernando Gómez-Herreros, Thanasis Margaritis, Olga Rodríguez-Galán, Vicent Pelechano, Victoria Begley, Gonzalo Millán-Zambrano, Macarena Morillo-Huesca, Mari Cruz Muñoz-Centeno, José E. Pérez-Ortín, Jesús de la Cruz, Frank C. P. Holstege y Sebastián Chávez. (2017) The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation. Nucleic Acids Research , 45(16), pp. 9302 - 9318 . ISSN: 0305-1048
- Blasco-Moreno B; de Campos-Mata L; Böttcher R; García-Martínez J; Jungfleisch J; Nedialkova DD; Chattopadhyay S; Gas ME; Oliva B; Pérez-Ortín JE; Leidel SA; Choder M; Díez J (2019) The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins. Nature Communications , 10, p. 1298 . ISSN: 2041-1723
- Paula Oliete-Calvo; Joan Serrano-Quílez; Carme Nuño-Cabanes; María E Pérez-Martínez; Luis M Soares; Bernhard Dichtl; Stephen Buratowski; José E Pérez-Ortín; Susana Rodríguez-Navarro (2018) A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export. Embo Reports , 19, p. e 45992 . ISSN: 1469-221X
- Antonio Jordán-Pla; Maria E. Pérez-Martínez; José E. Pérez-Ortín (2019) Measuring RNA polymerase activity genome-wide with high-resolution run-on- based methods. Methods-A Companion to Methods in Enzymology , 159-160, pp. 177 - 182 . ISSN: 1046-2023
- Olga Calvo; Nathalie Grandin; Antonio Jordán-Pla; Esperanza Miñambres; Noelia González-Polo; José E. Pérez-Ortín; Michel Charbonneau (2019) The telomeric Cdc13-Stn1-Ten1 complex regulates RNA polymerase II transcription. Nucleic Acids Research , 47(12), pp. 6250 - 6268 . ISSN: 0305-1048
- Victoria Begley; Daniel Corzo; Antonio Jordán-Pla; Abel Cuevas-Bermúdez; Lola de Miguel-Jiménez; David Pérez-Aguado; Mercedes Machuca-Ostos; Francisco Navarro; María José Chávez; José E. Pérez-Ortín; Sebastián Chávez (2019) The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4. Nucleic Acids Research , 47(18), pp. 9524 - 9541 . ISSN: 0305-1048
- José E. Pérez-Ortín; Vicente Tordera; Sebastián Chávez (2019) Homeostasis in the Central Dogma of molecular biology: the importance of mRNA instability. Rna Biology , 16, pp. 1659 - 1666 . ISSN: 1547-6286
- Romero AM; Ramos-Alonso L; Montellá-Manuel S; García-Martínez J; de la Torre-Ruiz MÁ; Pérez-Ortín JE; Martínez-Pastor MT; Puig S (2019) A genome-wide transcriptional study reveals that iron deficiency inhibits the yeast TORC1 pathway. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1862(9), p. 194414 . ISSN: 1874-9399
- A.I. Garrido-Godino; I. Gupta; F Gutiérrez-Santiago; A.B. Martínez-Padilla; A. Alekseenko; L.M. Steinmetz; J.E. Pérez-Ortín; V. Pelechano; F. Navarro (2021) Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast. Rna Biology , 18(8), pp. 1206 - 1220 . ISSN: 1547-6286
- Forés‐Martos, J.; Forte, A.; García‐Martínez, J; Pérez‐Ortín, J.E. (2021) A trans‐omics comparison reveals common gene expression strategies in four model organisms and exposes similarities and differences between them. Cells , 10(2), p. 334 . ISSN: 2073-4409
- Begley V; Jordán-Pla A; Peñate X; Garrido-Godino AI; Challal D; Cuevas-Bermúdez A; Mitjavila A; Barucco M; Gutiérrez G; Singh A; Alepuz P; Navarro F; Libri D; Pérez-Ortín JE; Chávez S. (2021) Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration. Rna Biology , 18(9), pp. 1310 - 1323 . ISSN: 1547-6286
- José García-Martínez; María E Pérez-Martínez; José E Pérez-Ortín; Paula Alepuz (2021) Recruitment of Xrn1 to stress-induced genes allows efficient transcription by controlling RNA polymerase II backtracking. Rna Biology , 18(10), pp. 1458 - 1474 . ISSN: 1547-6286
- Pérez-Ortín JE; Mena A; Barba-Aliaga M; Singh A; Chávez S; García-Martínez J. (2021) Cell volume homeostatically controls the rDNA repeat copy number and rRNA synthesis rate in yeast. Plos Genetics , 17(4), p. e1009520 . ISSN: 1553-7390
- Barba-Aliaga M.; Alepuz P.; Pérez-Ortín J.E. (2021) Eukaryotic RNA Polymerases: the many ways to transcribe a gene. Frontiers In Molecular Biosciences , 8(663209) . ISSN: 2296-889X
- García-Martínez J; Medina DA; Bellvis P; Sun M; Cramer P; Chávez S; Pérez-Ortín JE (2021) The total mRNA concentration buffering system in yeast is global rather than gene-specific. RNA-A Publication of the Rna Society , 27, pp. 1281 - 1290 . ISSN: 1355-8382
- Romero, A.M.; García-Martínez, J.; Pérez-Ortín, J.E.; Martínez-Pastor, M.T.; Puig, S. (2022) Changes in mRNA stability play an important role in the adaptation of yeast cells to iron deprivation. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1865, p. 194800 . ISSN: 1874-9399
- Antonio Jordán-Pla; José E Pérez-Ortín (2022) High-Resolution Deep Sequencing of Nascent Transcription in Yeast with BioGRO-seq. Methods in Molecular Biology , 2477, pp. 57 - 70 . ISSN: 1064-3745
- José E Pérez-Ortín; Sebastián Chávez (2022) Nucleo-cytoplasmic shuttling of RNA-binding factors: mRNA buffering and beyond. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1865, p. 194849 . ISSN: 1874-9399
- Vicente Arnau; Marina Barba-Aliaga; Gaurav Singh; Javier Ferri; José García-Martínez; José E. Pérez-Ortín (2022) A feedback mechanism controls rDNA copy number evolution in yeast independently of natural selection. Plos One , 17(9), p. e0272878 . ISSN: 1932-6203
- Shiladitya Chattopadhyay; Jose Garcia-Martinez; Gal Haimovich; Jonathan Fischer; Aya Khwaja; Oren Barkai; Silvia Gabriela Chuartzman; Maya Schuldiner; Ron Elran; Miriam I. Rosenberg; Shira Urim; Shubham Deshmukh; Katherine E. Bohnsack; Markus T. Bohnsack; Jose E. Perez-Ortin; Mordechai Choder (2022) RNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway. Nature Communications , 13(7184), pp. 1 - 17 . ISSN: 2041-1723
- José García-Martínez; Abhyudai Singh; Daniel Medina; Sebastián Chávez; José E. Pérez-Ortín (2023) Enhanced gene regulation by cooperation between mRNA decay and gene transcription. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1866, p. 194910 . ISSN: 1874-9399
- M. Kelbert; A. Jordan-Pla; L. de-Miguel-Jiménez; J García-Martínez; M. Selitrennik; A. Gutman; N Henig; S Granneman; J.E. Pérez-Ortín; S. Chávez; M. Choder (2023) The transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis and cytoplasmic decay. Elife , 12(RP90766) . ISSN: 2050-084X
- José E. Pérez-Ortín; María J. García-Marcelo; Irene Delgado-Roman; María C. Muñoz- Centeno; Sebastián Chávez (2024) Influence of cell volume on the gene transcription rate. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1867(195008) . ISSN: 1874-9399
- José E. Pérez Ortín; Antonio Jordán Pla; Yujie Zhang; Jorge Moreno García; Claudio Bassot; Marina Barba Aliaga; Leire de Campos‐Mata; Mordechai Choder; Juana Díez; Ilaria Piazza; Vicent Pelechano; José García Martínez (2024) Comparison of Xrn1 and Rat1 5′→3′ exoribonucleases in budding yeast supports the specific role of Xrn1 in cotranslational mRNA decay. Yeast , 41, pp. 458 - 472 . ISSN: 1097-0061
- Jordán-Pla, A; Zhang, Y; García-Martínez, J; Chattopadhyay, S; Forte, Anabel; Choder, M; Pelechano, V; Pérez-Ortín, J.E; (2025) Proper 5'-3' cotranslational mRNA decay in yeast requires import of Xrn1 to the nucleus. Plos One , 20(1), p. e0308195 . ISSN: 1932-6203
- Maya-Miles, D.; García-Martínez, J.; Cases, I.; Pasión, R.; de la Cruz, J.; Pérez-Ortín, J.E.; Muñoz-Centeno, M.C.; Chávez, S. (2025) Regulation of transcription elongation anticipates alternative gene expression strategies across the cell cycle. Plos One , 20(5), p. e0317650 . ISSN: 1932-6203
- Jordán-Pla, A.; Gupta, I.; de Miguel-Jiménez, L.; Steinmetz, L.M.; Chávez, S.; Pelechano V. y Pérez-Ortín, J.E. 2015 Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle Nucleic Acids Research Volumen 43. Número 2.
- Barbosa C, García-Martínez J, Pérez-Ortín JE, Mendes-Ferreira A. 2015 Comparative Transcriptomic Analysis Reveals Similarities and Dissimilarities in Saccharomyces cerevisiae Wine Strains Response to Nitrogen Availability Plos One Volumen 10. Número 4.
- Canadell D, García-Martínez J, Alepuz P, Pérez-Ortín JE, Ariño J. 2015 Impact of high pH stress on yeast gene expression: A comprehensive analysis of mRNA turnover during stress responses Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms Volumen 1849. Número 6.
- Juanes JM, Miguel A, Morales LJ, Pérez-Ortín JE, Arnau V. 2015 A web application for the unspecific detection of differentially expressed DNA regions in strand-specific expression data Bioinformatics Volumen 31. Número 19.
- Natalia Gómez-Navarro, Antonio Jordán-Pla, Francisco Estruch y José E. Pérez-Ortín. 2016 Defects in the NC2 repressor affect both canonical and non-coding RNA polymerase II transcription initiation in yeast Bmc Genomics Volumen 17.
- Tianlu Li; Nikki De Clercq; Daniel A. Medina; Elena Garre; Per Sunnerhagen; José E. Pérez-Ortín; Paula Alepuz. 2016 The mRNA cap-binding protein Cbc1 is required for high and timely expression of genes by promoting the accumulation of gene-specific activators at promoters Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms Volumen 1859.
- García-Martínez, José; Delgado-Ramos, Lidia; Ayala, Guillermo; Pelechano, Vicent; Medina, Daniel A.; Carrasco, Fany; González, Ramón; Andrés-León, Eduardo; Steinmetz, Lars; Warringer, Jonas; Chávez, Sebastián; Pérez-Ortín, José E. 2016 The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons Nucleic Acids Research Volumen 44.
- Garrido-Godino AI; García-López MC; García-Martínez J; Pelechano V; Medina DA; Pérez-Ortín JE; Navarro F. 2016 Rpb1 foot mutations demonstrate a major role of Rpb4 in mRNA stability during stress situations in yeast Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms Volumen 1859. Número 5.
- Sebastián Chávez; José García-Martínez;· Lidia Delgado-Ramos; José E. Pérez-Ortín. 2016 The Importance of controlling mRNA turnover during cell proliferation Current Genetics Volumen 62. Número 4.
- José García-Martínez; Kevin Troulé; Sebastián Chávez; José E. Pérez-Ortín. 2016 Growth Rate controls mRNA turnover in steady and non-steady states Rna Biology Volumen 13. Número 12.
Publicaciones en revistas
- Pérez-Ortín, J.E., (1997). Organización molecular del genoma de Saccharomyces cerevisiae. Organización y evolución del genoma eucariota. Marcadores moleculares. Colección Cursos, Congresos e Simposios.. . Volumen. 30 . (pp. 99 - 114). .
- Pérez-Ortín, J.E. y García Martínez, J, (2005). Genómica y proteómica de levaduras vínicas. Microbiología del vino. A.V. Carrascosa, R. González y R. Muñoz (eds).. . (pp. 185 - 209). .
- Tordera, V.; Del Olmo, M. Pérez-Ortín, J.E. y Matallana, E., (2007). Qüestions en Biologia Molecular. Colección 'Educació. Laboratori de Materials'. . Volumen. 10 . (pp. 1 - 259). .
- Ji., S.; Chaovalitwongsea, W.A.; Fefferman, N.; Yoo, W. y Pérez-Ortín, J.E., (2009). Mechanism-Based Clustering of Genome-Wide mRNA Levels: Roles of Transcription and Transcript-Degradation Rates. Clustering Challenges in Biological Networks. . (pp. 237 - 255). .
- Pérez-Ortín, J.E., del Olmo, M., García-Martínez, J., (2009). DNA arrays. Biology of microorganisms on grapes, in must and in wine. . (pp. 469 - 488). .
- García Martínez, J, Pelechano, V. y Pérez-Ortín, J.E., (2011). Genomic methods for evaluating transcription rates in yeast. Yeast Genetic Networks. . Volumen. 734 . Número. part 1 . (pp. 25 - 44). .
- Marín-Navarro, J., Jauhiainen, A., Moreno, J., Alepuz, P.M., Pérez-Ortín, P.M. y Sunnerhagen, P., (2011). Global estimation of mRNA stability in yeast. Yeast Genetic Networks. . Volumen. 734 . Número. part 1 . (pp. 3 - 23). .
- Pérez-Ortín, J.E.; Alepuz, P.; García-Martínez, J.; Tordera, V. y Arnay, V., (2014). Grupo Genómica Funcional de Levaduras. . . Número. 58 . (pp. 113 - 115). .
- Jordán-Pla, A., Miguel, A.; Serna, E. Pelechano. V. y Pérez-Ortín, J.E., (2016). Biotin-Genomic Run-On (Bio-GRO): A High-Resolution Method for the Analysis of Nascent Transcription in Yeast. Yeast Functional Genomics. . Volumen. 1361 . (pp. 125 - 139). .
- Ana Mendes-Ferreira, Marcel.lí del Olmo, José García-Martínez, José E. Pérez-Ortín, (2017). Functional Genomics in Wine Yeast: DNA Arrays and Next Generation Sequencing. Biology of Microorganisms on Grapes, in Must and in Wine. 2ª edición. Helmut König ¿ Gottfried Unden ¿ Jürgen Fröhlich, Editores. . (pp. 573 - 604). .
- García-Marcelo, M.J.; Singh, G.; Chávez, S.; Pérez-Ortín, J.E., (2025). Measurement of rRNA Synthesis Rate by 3H-Uracil Labeling in yeast. mRNA Decay: Methods and Protocols. . Volumen. 2863 . (pp. 183 - 204). .
Otras Publicaciones
- GARCIA MARTINEZ, JOSEPDI-Titular d'Universitat+Director/a de Departament
- García-Martínez, J; Barrio, E; Raga, J.A. and Latorre, A (1995) Mitochondrial DNA variability of striped dolphin (Stenella coeruleoalba) in the Mediterranean Spanish waters. Marine Mammal Science , 11(2), pp. 183 - 199 . ISSN: 0824-0469
- Martínez-Izquierdo, J.A; García-Martínez, J. and Vicient, C.M. (1997) What makes Grande1 retrotransposon different?. Genetica , 100, pp. 15 - 28 . ISSN: 0016-6707
- García-Martínez, J; Castro, J.A; Ramón, M; Latorre, A. and Moya, A. (1998) Mitochondrial DNA haplotype frequencies in natural and experimental populations of Drosophila subobscura. Genetics , 149, pp. 1377 - 1382 . ISSN: 0016-6731
- García-Martínez, J; Raga, J.A. and Latorre, A (1999) Genetic differentiation in the striped dolphin Stenella coeruleoalba from European waters according to mitochondrial DNA (mtDNA) restriction analysis. Molecular Ecology , 8(6), pp. 1069 - 1073 . ISSN: 0962-1083
- Pérez-Ortín, J.E.; García-Martínez, J. and Alberola T. M. (2002) DNA chips for yeast biotechnology. The case of wine yeasts. Journal of Biotechnology , 98, pp. 227 - 241 . ISSN: 0168-1656
- Carro, D.; García-Martínez, J; Pérez-Ortín, J.E. y Piña, B. (2003) Structural characterization of chromosome I size variants from a natural yeast strain. Yeast , 20, pp. 171 - 180 . ISSN: 1097-0061
- García-Martínez, J. and Martínez-Izquierdo, J.A. (2003) Study on the evolution of the Grande retrotransposon in the Zea genus. Molecular Biology and Evolution , 20(5), pp. 831 - 841 . ISSN: 0737-4038
- Alberola, T. M., García-Martínez, J., Antúnez, O., Viladevall, L., Barceló, A., Ariño, J. y Pérez-Ortín, J.E. (2004) A new set of DNA macrochips for the yeast Saccharomyces cerevisiae: features and uses. International Microbiology , 7(3), pp. 199 - 206 . ISSN: 1139-6709
- Pérez-Ortín, J.E. y García-Martínez, J. (2004) Evaluation of transcription rates at the genomic level. Bioforum Europe , 8(5), pp. 46 - 48 . ISSN: 1611-597X
- Bellí, G.; Molina, M.M.; García Martínez, José; Pérez-Ortín, José Enrique; Herrero, Enrique (2004) Saccharomyces cerevisiae glutaredoxin 5-deficient cells subjected to constitutive oxidizing conditions are affected in the expression of specific sets of genes. Journal of Biological Chemistry , 279(13), pp. 12386 - 12395 . ISSN: 0021-9258
- Garcia Martinez, José; Aranda Fernández, Agustín; Pérez Ortín, José Enrique (2004) Genomic run-on evaluates transcription rates for all yeast genes and identifies gene regulatory mechanisms. Molecular Cell , 15(2), pp. 303 - 313 . ISSN: 1097-2765
- Güldener, U; Münsterkötter, M.; Kastenmüller, G; Strack1, N; van Helden, J.; Lemer, C.; Richelles, J.; Wodak, S.J.; García Martínez, José; Pérez Ortín, José E.; Michael, H.; Kaps, A.; Talla, E.; Dujon, B.; André, B.; Souciet, J.L.; De Montigny, J.; Bon, E.; Gaillardin, C. y Mewes, H.W (2005) CYGD: The Comprehensive Yeast Genome Database. Nucleic Acids Research , 33(suppl 1), pp. D364 - D368 . ISSN: 0305-1048
- Pelechano, Vicente José; García Martínez, José; Pérez Ortín, José Enrique (2006) A genomic study of the Inter-ORF distances in Saccharomyces cerevisiae. Yeast , 23, pp. 689 - 699 . ISSN: 1097-0061
- Castillo, L; Martínez, A.I; Garcerá, A; García-Martínez, J; Ruiz-Herrera, J; Valentín, E. and Sentandreu, R (2006) Genomic response programs of Candida albicans following protoplasting and regeneration. Fungal Genetics and Biology , 43, pp. 124 - 134 . ISSN: 1087-1845
- Mendes-Ferreira A.; Olmo Muñoz, Marcel·lí del; García Martínez José; Jiménez Martí Elena; Mendes-Faia A.; Pérez Ortín, José Enrique; Leão C. (2007) Transcriptional response of Saccharomyces cerevisiae to different nitrogen concentrations during alcoholic fermentation. Applied and Environmental Microbiology , 73(9), pp. 3049 - 3060 . ISSN: 0099-2240
- Rosaleny Peralvo, Lorena Estefanía; Ruiz García, Ana Belén; García Martínez, José; Pérez Ortín, José Enrique; Tordera Donderis, Vicente (2007) The Sas3p and Gcn5p histone acetyltransferases are recruited to similar genes. Genome biology , 8(6), p. R119 . ISSN: 1474-7596
- Mendes-Ferreira A.; Olmo Muñoz, Marcel·li del; García Martínez José; Jiménez Martí, Elena; Leão, C.; Mendes-Faia A, Pérez Ortín José E. (2007) Saccharomyces cerevisiae signature genes for predicting nitrogen deficiency during alcoholic fermentation. Applied and Environmental Microbiology , 73(16), pp. 5363 - 5369 . ISSN: 0099-2240
- García Martínez, José; González Candelas, Fernando; Pérez Ortín, José Enrique (2007) Common gene expression strategies revealed by genome-wide analysis in yeast. Genome biology , 8, p. R222 . ISSN: 1474-7596
- Molina-Navarro, M.M.; Castells-Roca, L.; Bellí, G.; García-Martínez, J.; Marín-Navarro, J.; Moreno, J. Pérez-Ortín, J.E. y Herrero, E. (2008) Comprehensive transcriptional analysis of the oxidative response in yeast. Journal of Biological Chemistry , 283, pp. 17908 - 17918 . ISSN: 0021-9258
- Campo, S; Manrique, S; García-Martínez, J. and San Segundo, B (2008) Production of Cecropin A in transgenic rice plants has an impact on host gene expression. Plant Biotechnology Journal , 6, pp. 585 - 608 . ISSN: 1467-7644
- Belloch, Carmela; Pérez Torrado, Roberto; González, Sara S.; Pérez Ortín, José Enrique; García Martínez, José; Querol Simón, Amparo; Barrio Esparducer, Eladio (2009) Chimeric Genomes of Natural Hybrids of Saccharomyces cerevisiae and Saccharomyces kudriavzevii. Applied and Environmental Microbiology , 75(8), pp. 2534 - 2544 . ISSN: 0099-2240
- Pelechano García, Vicente José; Jimeno-González, Silvia; Rodríguez-Gil, Alfonso; García Martínez, José; Pérez Ortín, José Enrique; Chávez, Sebastián (2009) Regulon-specific control of transcription elongation across the yeast genome. PLOS genetics , 5(8), p. e1000614 . ISSN: 1553-7390
- Bermúdez, Ignacio; García Martínez, José; Pérez Ortín, José Enrique; Roca, Joaquim (2010) A method for genome-wide analysis of DNA helical tension by means of psoralen-DNA photobinding. Nucleic Acids Research , 38(19), p. e182 . ISSN: 0305-1048
- Rodríguez-Gil, Alfonso; García Martínez, José; Pelechano García, Vicente José; Muñoz-Centeno, María de la Cruz; Geli, Vincent; Pérez Ortín, José Enrique; Chávez, Sebastián (2010) The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors. Nucleic Acids Research , 38(14), pp. 4651 - 4664 . ISSN: 0305-1048
- Castells-Roca, L.; García-Martínez, J.; Moreno Mariño, Joaquín; Herrero, E.; Bellí, G. y Pérez Ortín, José Enrique (2011) Heat shock response in yeast involver changes in both transcription rates and mRNA stabilities. Plos One , 6(2), p. e17272 . ISSN: 1932-6203
- García Martínez, José; Ayala Gallego, Guillermo; Pelechano García, Vicente José; Chávez, S.; Herrero, E.; Pérez Ortín, José Enrique (2012) The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast. Transcription , 3(1), pp. 39 - 44 . ISSN: 2154-1264
- Campos-Soriano, L; García-Martínez, J. and San Segundo, B. (2012) The arbuscular mycorrhizal symbiosis promotes systemic induction of regulatory defence-related genes in rice leaves and confers resistance to pathogen infection. Molecular Plant Pathology , 13(6), pp. 579 - 592 . ISSN: 1464-6722
- Nikolaou, C.; Bermúdez, I.; Manichanh, C.; García-Martínez, José; Guigó, R.; Pérez-Ortín, José E.; Roca, J. (2013) Topoisomerase II regulates yeast genes with singular chromatin architectures. Nucleic Acids Research , 41(20), pp. 9243 - 9256 . ISSN: 0305-1048
- Barbosa C, García-Martínez J, Pérez-Ortín JE, Mendes-Ferreira A. (2015) Comparative Transcriptomic Analysis Reveals Similarities and Dissimilarities in Saccharomyces cerevisiae Wine Strains Response to Nitrogen Availability. Plos One , 10(4), p. e0122709 . ISSN: 1932-6203
- Canadell D, García-Martínez J, Alepuz P, Pérez-Ortín JE, Ariño J. (2015) Impact of high pH stress on yeast gene expression: A comprehensive analysis of mRNA turnover during stress responses. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1849(6), pp. 653 - 664 . ISSN: 1874-9399
- García-Martínez, José; Delgado-Ramos, Lidia; Ayala, Guillermo; Pelechano, Vicent; Medina, Daniel A.; Carrasco, Fany; González, Ramón; Andrés-León, Eduardo; Steinmetz, Lars; Warringer, Jonas; Chávez, Sebastián; Pérez-Ortín, José E (2016) The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons. Nucleic Acids Research , 44, pp. 3643 - 3658 . ISSN: 0305-1048
- Garrido-Godino AI; García-López MC; García-Martínez J; Pelechano V; Medina DA; Pérez-Ortín JE; Navarro F. (2016) Rpb1 foot mutations demonstrate a major role of Rpb4 in mRNA stability during stress situations in yeast. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1859(5), pp. 731 - 743 . ISSN: 1874-9399
- Sebastián Chávez; José García-Martínez;· Lidia Delgado-Ramos; José E. Pérez-Ortín (2016) The Importance of controlling mRNA turnover during cell proliferation. Current Genetics , 62(4), pp. 701 - 710 . ISSN: 0172-8083
- José García-Martínez; Kevin Troulé; Sebastián Chávez; José E. Pérez-Ortín (2016) Growth Rate controls mRNA turnover in steady and non-steady states. Rna Biology , 13(12), pp. 1175 - 1181 . ISSN: 1547-6286
- Adriana Mena, Daniel A. Medina, José García-Martínez, Victoria Begley, Abhyudai Singh, Sebastián Chávez, Mari C. Muñoz-Centeno, José E. Pérez-Ortín (2017) Asymmetric cell division requires specific mechanisms for adjusting global transcription. Nucleic Acids Research , 45(21), pp. 12401 - 12412 . ISSN: 0305-1048
- Varinia García‑Molinero, José García‑Martínez, Rohit Reja, Pedro Furió‑Tarí, Oreto Antúnez, Vinesh Vinayachandran, Ana Conesa, B. Franklin Pugh, José E. Pérez‑Ortín, Susana Rodríguez‑Navarro (2018) The SAGA/TREX‑2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally. Epigenetics & Chromatin , 11(13), pp. 1 - 12 . ISSN: 1756-8935
- Blasco-Moreno B; de Campos-Mata L; Böttcher R; García-Martínez J; Jungfleisch J; Nedialkova DD; Chattopadhyay S; Gas ME; Oliva B; Pérez-Ortín JE; Leidel SA; Choder M; Díez J (2019) The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins. Nature Communications , 10, p. 1298 . ISSN: 2041-1723
- Romero AM; Ramos-Alonso L; Montellá-Manuel S; García-Martínez J; de la Torre-Ruiz MÁ; Pérez-Ortín JE; Martínez-Pastor MT; Puig S (2019) A genome-wide transcriptional study reveals that iron deficiency inhibits the yeast TORC1 pathway. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1862(9), p. 194414 . ISSN: 1874-9399
- Forés‐Martos, J.; Forte, A.; García‐Martínez, J; Pérez‐Ortín, J.E. (2021) A trans‐omics comparison reveals common gene expression strategies in four model organisms and exposes similarities and differences between them. Cells , 10(2), p. 334 . ISSN: 2073-4409
- Pérez-Ortín JE; Mena A; Barba-Aliaga M; Singh A; Chávez S; García-Martínez J. (2021) Cell volume homeostatically controls the rDNA repeat copy number and rRNA synthesis rate in yeast. Plos Genetics , 17(4), p. e1009520 . ISSN: 1553-7390
- García-Martínez J; Medina DA; Bellvis P; Sun M; Cramer P; Chávez S; Pérez-Ortín JE (2021) The total mRNA concentration buffering system in yeast is global rather than gene-specific. RNA-A Publication of the Rna Society , 27, pp. 1281 - 1290 . ISSN: 1355-8382
- José García-Martínez; María E Pérez-Martínez; José E Pérez-Ortín; Paula Alepuz (2021) Recruitment of Xrn1 to stress-induced genes allows efficient transcription by controlling RNA polymerase II backtracking. Rna Biology , 18(10), pp. 1458 - 1474 . ISSN: 1547-6286
- Romero, A.M.; García-Martínez, J.; Pérez-Ortín, J.E.; Martínez-Pastor, M.T.; Puig, S. (2022) Changes in mRNA stability play an important role in the adaptation of yeast cells to iron deprivation. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms , 1865, p. 194800 . ISSN: 1874-9399
- Vicente Arnau; Marina Barba-Aliaga; Gaurav Singh; Javier Ferri; José García-Martínez; José E. Pérez-Ortín (2022) A feedback mechanism controls rDNA copy number evolution in yeast independently of natural selection. Plos One , 17(9), p. e0272878 . ISSN: 1932-6203
- Shiladitya Chattopadhyay; Jose Garcia-Martinez; Gal Haimovich; Jonathan Fischer; Aya Khwaja; Oren Barkai; Silvia Gabriela Chuartzman; Maya Schuldiner; Ron Elran; Miriam I. Rosenberg; Shira Urim; Shubham Deshmukh; Katherine E. Bohnsack; Markus T. Bohnsack; Jose E. Perez-Ortin; Mordechai Choder (2022) RNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway. Nature Communications , 13(7184), pp. 1 - 17 . ISSN: 2041-1723
Publicaciones en revistas
Grupo de Investigación en Expresión Génica en Eucariontes: del DNA a las Proteínas (EGE-DtoP)
© 2025 UV. - Facultad de Ciencias Biológicas. Dep. de Bioquímica y Biología Molecular / Institut BioTecMed. C/ Doctor Moliner, 50 Burjassot (Valencia) egedtop@uv.es