Analysis of the neutralising and protective activity of polyclonal serum and monoclonal antibodies against viruses
Assessing the carbohydrates malabsorption (lactose, fructose)-intestinal parasitosis relationship and the influence of the latter on child development.
Characterisation of the distribution of mutational effects on the biological efficacy of RNA viruses
Characterisation of viral antigenic epitopes
Determination of SARS-CoV-2 in environmental samples
Development and assessment of rapid diagnostic methods for gastrointestinal bacterial and viral infections
Development of epidemiological studies on food-transmissible parasites
Development of epidemiological studies on helminths and arthropods of health interest with the development of GISs to analyse the effect of climate change.
Development of omics and exovesicle studies in human / animal helminths and their applicability in diagnosis, treatment and vaccination.
Development of probiotic microorganisms with protective capacity against viral infections
Development of viral vaccines
Elaboration of epidemiological studies on food-transmissible parasites
Epidemiologic analysis of infectious diseases through molecular biology methods and study on disease outbreaks
Estimation of the mutation rate of animal, plant and bacteriophage viruses (both RNA and DNA)
Evaluation of antiviral compounds on SARS-CoV-2 in the BSL3 (Biosafety level 3 Laboratory)
Evaluation of diagnostic methods
Evaluation of infection rates at the population level through rapid serological tests
Experimental model Aspiculuris treraptera in mice (CD1). Giardia intestinalis trophozoites of axenic cultivation
Use of animal experimental models (different strains of mice and rats. Animal Production Section, SCSIE). Isolation, analysis and characterisation of nucleic acids (DNA and RNA, especially miRNAs) and proteins via molecular biology techniques (restriction, PCR amplification, sequencing, dot-blot, southern and northern blot, western-blot). Bioinformatic analysis. Cloning and gene expression in heterologous systems (in bacteria, yeasts and superior eukaryotic cells, as well as in “cell-free” expression systems); production and purification of recombinant proteins. Production of polyclonal antibodies in rabbits. Cell cultures, SCSIE.
Genomics-related services; Proteomics; Microscopy; Electron microscopy (SEM and TEM) and Confocal laser microscopy; Cell culture; Flow cytometry and Animal production
Genomics-related services; Proteomics; Microscopy; Electron microscopy (SEM and TEM) and Confocal laser microscopy; Cell culture; Flow cytometry and Animal production.
Identification of molecular determinants that condition susceptibility to gastrointestinal viral diseases
Identification of transmission routes, gene introduction and spread, and drug resistance variants in viruses and bacteria
In-vitro and in-vitro estimation of mutation rates of different human viruses of high biomedical relevance, such as HIV-1 or Hepatitis C
Molecular epidemiology studies of viral infections: detection of new genotypes and variants
Quantitative estimation of RNA virus mutation rates
Rapid Immunoglobulin detection (IgA secretory, IgGs and IgMs) for the early diagnosis of SARS-COV-2 via portable graphene biosensor.
Screening for antivirals and antibodies to SARS-CoV-2
Seroepidemiology studies of viral infections
Studies on the experimental evolution of oncolytic viruses for the development of therapeutic applications
Study of evolutionary processes using viruses as model organisms
Study of the evolution of complete genomes and genes in bacteria and viruses
Study of the interactions between enteric virus-host, enteric virus-intestinal microbiota and intestinal microbiota-host
Study of the pathogenic mechanisms and the immune response to infections by the two main enteric viruses (rotavirus and norovirus)
Study of the spread of pathogenic microorganisms (bacteria and viruses) in human populations and natural reservoirs through genetic and genomic analysis for the purposes of epidemiological care and control
Study on evolutionary patterns of viruses and other pathogenic organisms via mutation and selection mechanisms
Study on the dynamic of pathogenic and non-pathogenic microorganisms with their hosts, especially human ones
Technical advice and consultancy in molecular studies related to genetic variability
Technical advice and consultancy on the microbiota impact on human health
Technical advice and scientific consultancy in genetics
Technical advice and scientific consultancy in quantitative genetics and analysis for the impact of multiple genes on the phenotype
Training in Food Parasitology
Specialisation course in Food Parasitology since 2001.
Training in Parasitic Zoonosis
Training given to health workers by the research group on the main parasitic zoonosis since 2015.
