In this line of research, new non-invasive microscopy techniques with high optical sectioning are developed, such as confocal microscopy, structured illumination microscopy (SIM) or digital holographic microscopy (DHM).
Development in the implementation of 3D image capture techniques based on taking multiple images with different perspectives. This multi-perspective information allows both the reconstruction of the original 3D scene and the development of new 3D digital processing techniques.
Biomedical applications of bacteriophages, including diagnosis, prevention, and therapy, as an alternative tool against multidrug-resistant bacteria. Isolation and characterization of novel phages, directed evolution for phage optimization, resistant emergence, and nanotechnology.
Isolation and characterisation of extracellular vesicles (EVs) in different helminth parasites. Identification of molecules present in EVs. Analysis for the usefulness of EVs in helminthiasis control and other diseases (diagnosis, vaccination and treatment).
Molecular and genetic basis of neurocognitive alterations in patients with SMI, in order to develop biomarkers, diagnostic assessment tools and therapeutic interventions helping to improve the functional prognosis, the autonomy and the life quality of these people.
Diffractive lenses are very interesting elements because they are compact, lightweight and economical optical components. In this line of research, new designs are being developed for application in ophthalmology in the form of both intraocular (IOL) lenses and contact lenses.
Optical devices for manipulating pulses of tens of femtoseconds by using diffractive optical elements allowing spatial control of the wavefront of the pulsed beam, as well as the shaping of the temporal envelope of the ultra-short pulses.
Comprehend the unexpected associations between apparently different diseases, like cancer and certain diseases of the central nervous system.
Epidemiological (life cycle, transmission, population dynamic) and ecological (influence of biotic and abiotic factors) analysis of human and animal parasites (especially rodents). Analysis of behaviour and response of parasites after natural disasters.
Study of the evolution of complete genomes and the genes present in them, with special emphasis on bacteria and viruses.
We use viruses as model organisms in the laboratory to study evolutionary processes on an experimental basis.
Epidemiological study of food-transmitted human parasites (protozoa and helminths). Study of the influence of intrinsic and extrinsic factor on parasitism. Morphological and molecular diagnosis and identification of parasite species. Anisakiasis study.
Prevention of fragility signs in populations at risk by assessing human functions (functional and neurocognitive assessment) and by incorporating nutritional medicine studies on Omega 3.
Creation of Geographic Information Systems with the use of satellite images and thematic maps (climate, surface, parasitological parameters, etc.) for the modelling of epidemiology and the transmission of human / animal parasites, as well as the influence of climate change on them.
Networking on the burden of disease.
Diagnosis and epidemiological study of human ectoparasite arthropods (mosquitoes, myiasis, lice, bedbugs, etc.). Pest control and vectors on an individual level. Analysis of vector-transmitted parasitic diseases and influence of climate change on them.
Our goal is to explore the mechanistic principles of membrane protein insertion, folding and assembly into lipid membranes and to investigate the factors that determine membrane protein stability.
Overexpression of membrane proteins is often essential for structural and functional studies, but yields are frequently too low. Therefore, we investigate the consequences of overexpression of different membrane proteins in search for new components to improve such yields.
Modelling and design of waveguides and other photonic devices, such as photonic-crystal fibers, integrated semiconductor and dielectric guides and resonators, fibre optic lasers, or metamaterials.
Use of genetic and genomic information of pathogenic microorganisms (bacteria and viruses) to study their spread in human populations and in their natural reservoirs, complementing the tasks of epidemiological care and control.
There's an analysis for the parasites-food intolerance relationship and the prevalence, transmission routes and risk factors of suffering from intestinal parasitosis, the correlation between parasitosis and the reception of breastfeeding, as well as the parasites-child development relationship.
Study of molecular interactions between helminth parasites and their hosts. Tools destined to the control of said parasitosis (proteins and recombinant peptides along with polyclonal antibodies) stem from identified molecules.
Epidemiological study of teniasis / cisticercosis, with special reference to the third new parasitic tapeworm: Taenia asiatica. Ultrastructural studies of infective forms. Secretomics analysis of cisticercosis' infective forms (eggs) of the three human Taenia species.
Monitoring natural and anthropogenic environments for disease surveillance, specially viral outbreaks. Detection of emerging viruses in natural environments and development of quantification techniques for population monitoring. Study of new transmission routes of emerging viruses.
Using various experimental approaches, we aim to identify and characterise mechanisms in the generation of RNA virus diversity, and to obtain quantitative estimates of mutation rates in RNA viruses.
