The goal of our group is to deepen the knowledge of the host immune response against the opportunistic fungal pathogen Candida albicans.

Toll-like receptors (TLR) is the most important type of pattern recognition receptors and they are mainly present in neutrophils, macrophages and dendritic cells. They are responsible for detecting pathogenic microorganisms and initiate immune response against them.

Our group studies the role of TLRs in the defence against candidiasis, using an experimental model of candidiasis in knockout mice for different TLR (TLR2-/ -, TLR4-/ -).