Researchers of the Molecular Biology and Biochemistry Department of the Universitat de València/ Biotecmed Institute published in Scientia Global an outreach article about the eIF5A, involved in cancer and ageing, that describes its role in the maintenance of protein delivery to the mitochondria

The researchers of the Universitat de València Marina Barba-Aliaga, Vanessa Bernal y Paula Alepuz, in collaboration with the group of Dr. Brian Zid in the University of California (UCLA), have published in Scientia Global, the article ‘Proteins on the Move: Gateways into Mitochondria’, that explains how this protein maintains the mitochondrial breath. The innovative research of this collaboration has provided new knowledge on the complex mechanisms of production and transport of proteins to mitochondria. 

Scientia Global presents a some research publications that cover themes of science, technology and education. Its objective is to close the breach between science, education, policy, research, the government and the private sector "Opening a dialogue between science and society We’re not disrupting an existing format, we’re creating a new one". 

The initial factor of the eukaryote translation 5A (eIF5A) is an essential factor for the actual translation in almost every living organism. Helping ribosomes, the molecular machines that build proteins, in the translation of proteins that contain specific amino acids The need of eIF5A is related with various diseases, as well as with ageing. Even if it is known that the eIF5A is essential for the mitochondrial function, it has not been describe the specific mechanism that links them.

• Link to the article (Scientia Global) written by Luisa Postlethwaite
• DOI http://doi.org/10.33548/SCIENTIA1235
• Download ebook (pdf)
• Web of the research group EGE-DtoP Eukaryotic Gene Expression Research Group: from DNA to Proteins (https://www.uv.es/egedtop)