Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput Bioanalysis

Description

Quality and methodology applied to laboratories of routine (ISO 17205 Standard) and research: Development of ad hoc metrological tools, technical protocols, acceptance criteria, validation, quality assurance, control charts, uncertainty, including supporting software. Design of experiments, optimisation, simulation of future results. Research and development of high-throughput (bio)analysis methods (Liquid chromatography, Capillary electrophoresis, Mass spectrometry) for the separation and determination of molecules (including chiral) with analytical and bioanalytical applications. (Bio)sensors. Chemical assays of relevant compounds in environmental samples (water, sludge, soil, etc.).

Added value: In vitro estimation of ecotoxicological parameters. Chemical assays of bioactive molecules (in urine, plasma, saliva, etc.). Added value In vitro estimation of ADME/TOX indicators. Development of molecular biointeraction models. Computational simulation methods (“in silico” via “Molecular Docking”). Pharmacophores. QSAR.

Goals CT

Quality and metrology applied to laboratories.
Development of metrological tools for companies and laboratories.
Research and development of high-throughput (bio)analysis methods.
Chemical assays of relevant compounds in environmental samples and bioactive molecules.

Research lines

Analysis of bioactive molecules
Chemical assays of bioactive molecules (in urine, plasma, saliva, etc.). Added value In vitro estimation of ADME/TOX indicators.
Molecular and computational biointeraction
Development of molecular biointeraction models. Computational simulation methods (“in silico” via “Molecular Docking”). Pharmacophores. QSAR.
Quality and Metrology in Laboratories
ISO 17205 Standard. Development of ad hoc metrological tools, technical protocols, acceptance criteria, validation, quality assurance, control charts, uncertainty, including supporting software. Design of experiments, optimisation, simulation of future results.
R&D in (bio)analytical methods
Research and development of high-throughput (bio)analysis methods (Liquid chromatography, Capillary electrophoresis, Mass spectrometry) for the separation and determination of molecules (including chiral) with analytical and bioanalytical applications. (Bio)sensors.
Analysis of environmental samples
Chemical assays of relevant compounds in environmental samples (water, sludge, soil, etc.). Added value: In vitro estimation of ecotoxicological parameters.

Management