IPT; EMT; INT; TAR
-80 °C freezer for cryopreservation of samples and biological prodcuts.
recording of neurotoxic substances in saliva in humans
3D culture methodology from surgical resection specimens.
In vivo models of lung tumours, obtained by injection of CSCs in murine models.
Continuous physiological activity recording system for field studies, since it is an ambulatory system.
The ASDE Driver Test N-845 Psycho-technical Equipment is a standardised equipment (approved by the D.G.T.) and registered with the Spanish Medicines Agency as a Medical Device, for carrying out psycho-technical tests by means of a battery of totally independent and specific tests to measure the psychophysical and psychological aptitudes of drivers and firearms carriers.
Triaxial accelerometers.
Access to the facilities of the Servei Central de Suport a la Investigació Experimental (SCSIE), which include infrared spectroscopy (IR), nuclear magnetic resonance (NMR), mass spectrometry (MS), X-rays, etc.
Assessment of motor behaviour using a computerised activimetry system.
Morphological, morphometric and molecular protozoa diagnosis; diagnosis of helminths and arthropod parasites of human and animal nature. Epidemiological modelling of human and animal parasitic diseases via creation of Geographical Information Systems (GIS).
Platelet aggregation measurement system (whole blood or PRP).
The Agilent 2100 Bioanalyzer is a microfluidic-based platform designed for sizing, quantification and quality control of DNA and RNA by small-chip electrophoresis in a single instrument. Results are obtained in a short time in an automated way, directly in digital format.
The miniaturisation of analytical instruments offers numerous advantages over conventional techniques. These include improved data accuracy and reproducibility, reduced analysis times, minimal sample consumption and improved automation and integration of complex workflows.
System for the characterisation of pain.
Expertise in modifier genetic screens, transcriptomics and proteomics.
Determination of the cellular fatty acid composition of microbial strains using gas chromatography.
The research team has the necessary resources to develop individualised analyses and reports for athletes and/or people who wish to carry out an evaluation of the physical activity practised (walking, running, etc...), with specific instruments and qualified personnel.
Research unit for the analysis of sports practice.
Animal behaviour laboratory consisting of 3 animal facilities in accordance with current regulations, various experimental rooms for behaviour, surgery, histology and HPLC.
Model that records analgesia threshold in mice
Different Drosophila lines for the study of Friedreich’s Ataxia and Spastic Paraplegia Type 7:
- With generalised and tissue-specific reduction/increase of the expression of the endogenous gene that encodes frataxin and paraplegin respectively.
- With expression of the human genes.
- With expression of the human mutation responsible for both diseases.
Scientifically validated elevated maze, plus-maze and zero-maze tests as suitable animal models for anxiety assessment.
Scientifically validated object recognition, passive avoidance and water maze tests as suitable models for learning assessment.
Equipment of the Experimental Aquarium Plant Laboratory.
The Array platform, designed by Affymetrix, provides a holistic study of organisms from the perspective of systems biology, a better understanding of biological properties and interactions as a whole. This technology provides the flexibility to study a specific subset of genes of interest or to be able to focus on the study of the genome at a global level in order to understand and define in depth the complex mechanisms and networks that underlie biological processes and diseases.
Modulation transfer function and contrast sensitivity measurements. Tests to detect colour vision defects (anomaloscope, pseudoisochromatic tests, sorting tests, measurement of colour thresholds). Perimetry (standard, blue-yellow, frequency doubling and flicker).
At the Faculty of Psychology, in the teaching laboratory unit (Stage 3), we have installed, at the expense of our projects, complete equipment for the video recording and reproduction of the evaluation, treatment and experimental sessions that we carry out with people affected by OC spectrum disorders and the general population.
Automatic cell counter and size analyser.
Specialised library.
Lab spaces disposition, equipped with the necessary inventory and fungible material to finalise investigations in detailed lines. Laboratories equipped with ELISA readers, mono- and two-dimensional electrophoresis systems, ChemiDoc XRS Bio-Rad analysis and documentation system, normal and real-time PCR thermocyclers (real-time PCR CFX96 Touch system; Bio-Rad). Electroporator, incubators, coolers, -20 and -80 freezers. Semi-wet transfer equipment. Refrigerated centrifuges with fixed and oscillating rotors, for various tube sizes. Floor and tabletop ultracentrifuges. Autoclaves, water purification systems. Optic and fluorescence microscopes. Staining trays and specific staining reagents. ELISA plate reader and real-time thermocycler.
Serum, plasma or saliva samples from persons assessed form a frailty and comprehensive geriatric assessment point of view.
Biomechanics laboratory equipped with instruments and technology for the biomechanical analysis of physical activity and sport. Faculty of Physical Activity and Sports Sciences. Blasco Ibáñez Campus, Universitat de Val
Biomechanics laboratory equipped with instruments and technology for the biomechanical analysis of physical activity and sport.
Faculty of Physical Activity and Sport Sciences. Ontinyent Campus, Universitat de València.
Large space equipped with technology and research material in the field of biomechanics applied to improving sports performance and health.
Tanita BF350 scale (TANITA Corporation, Arlington Heights, IL, USA).
Recording of alcohol in exhaled air in humans.
Neuropsychological evaluation system that includes memory, attention, executive functions and social cognition tests, among others.
Signal acquisition system.
Contact colorimeter for colour measurement on screens (Cambridge Research Ltd.).
Assisted electronic design package for the design of integrated and printed circuits.
Parallel computing server farm with capacity for 80 processors.
Various 21-inch CRT monitors (Sony and Mitshubisi), colourimetrically characterised, computer-controlled, for psychophysical measurements and perceptual training.
Driving simulator to perform different tests related to car driving.
The care unit of patients with craniofacial fissures and anomalies was created in response to the need for a specialised multidisciplinary referral unit to care for families with children with structural and functional anomalies: children with llavi-palatal fissures and craniofacial syndromes (22q11. 2, Crouzon, Pfeiffer, Treacher Collins, etc.), from birth to adulthood.
The objectives of this unit, in addition to professional support to families, are to develop actions related to the prevention, assessment, diagnosis, rehabilitation and research of disorders of vision, speech, resonance and feeding in people with fractures and other craniofacial anomalie.
Cell culture unit with class I laminar flow cabinet.
Cell culture unit with class II laminar flow cabinet and IG750 hypoxia incubator (JOUAN).
Cell culture unit with class II laminar flow cabinet.
Cell culture unit with class II laminar flow cabinet and INVIVO2 400 hypoxia chamber (RUSKINN).
Cell Separator equipped with 6 lasers, biosafety cabinet and aerosol extraction. It allows, firstly, the rapid measurement of morphological and functional parameters of a large number of individual cells suspended in liquid medium. For this, cells are initially labelled with fluorochrome-conjugated antibodies, or fluorescent probes that bind to proteins located on the cell surface or inside the cell. The scattered light and fluorescence emitted by the markers as the cells are passed one by one through the different lasers allows simultaneous measurement of structural features and various parameters in each of these cells.
In addition, after analysis, it is possible to separate and collect subpopulations of interest from the sample for further studies.
Complete cell and molecular biology laboratory equipment.
We perform cultures of various cell types, both primary and line maintenance. Our main focus is the primary culture of neurospheres, although we are also performing primary cultures of mesenchymal cells and the maintenance of several tumour lines.
Laboratory located in the Department of Pathology, Faculty of Medicine and Dentistry, Universitat de València.
In vitro transcription/translation systems.
In accordance with European and Spanish regulations, all experiments with live animals are carried out in the facilities of the animal production service of the Universitat de València. Similarly, work with cell cultures or primary cell cultures is carried out in the cell culture unit of the University. Other services are occasionally used by the group.
Detector and chamber for chemiluminescence and fluorescence (Western blotting and DNA electrophoresis).
Interferential filters tuned to different visible wavelengths. Coloured lenses for use as optical aids for individuals with dyschromatopsia.
Circular Dichroism Spectrometer.
Open-plan laboratory for clinical research, enabling physiotherapy assessments and interventions to be carried out.
Tests to assess: emotional processing, theory of mind and attributional style.
Assessment of cognitive status in humans through questionnaires such as Trai Making Test (TMT A and TMT B), Weschler Memory Scale, Mini-Cog, Mini-Mental State Examination (MMSE), etc.
PCR oligos pairs amplifying genes or parts of genes of S. cerevisiae.
Collection of fibroblast cell lines established from tumour and fibrotic tissue.
Collection of lung carcinoma cell lines established from tumour tissue
Collection of tumour tissue samples from lung cancer patients.
Collection of tumour tissue samples from patients with pulmonary fibrosis.
Numerous mutant strains of S. cerevisiae have been developed throughout the group's history.
Evaluation of the activity and spatial homogeneity of display devices. Colourimetric characterisation of display devices and characterisation by means of physical, polynomial models or LUT tables.
Matlab library for colour spaces, vision models, control and stimulus generation, developed by different members of the Optics Department, including members of our group.
Anomaloscope. Ishihara test. Sorting tests (D15, Lanthony, Farnsworth-Munsell 100-tone). Threshold measurement test (Cambridge Colour Test. Optopad).
Performance of tests for the assessment of the frail patient.
Heterogeneous computer cluster, consisting of multicore servers and GPU-based servers.
Assessment of the reinforcing effect of drugs.
It allows the scanning and acquisition of specific volume of the patient's head and generates 3D data, using a radiation dose many times lower than the dose used by medical tomographs.
Device for point-to-point measurement of corneal curvature by means of placido discs.
Corneas and crystalline lenses from deceased donor and various animal species (pig, rabbit, horse, chicken, sheep).
Coulter counter for estimating cell number and cell size.
Cultius cel·lulars de cèl·lules epitelials, cèl·lules musculars, cèl·lules endotelials, fibroblasts, queratinòcits i cultius 3d.
Culture laboratory dedicated to the collection and maintenance of human vascular cells.
Room equipped with two laminar flow cabinets, thermostatised bath, centrifuge, normal inverted microscope, inverted microscope with fluorescence module.
Fully equipped culture room with biological safety cabinets and CO2 incubators.
Storage service for biological material under controlled conditions.
Upper limb pedalling system for stress testing.
Fully equipped laboratory for sample preparation, acquisition, separation and analysis by flow cytometry.
InAlyzer (MEDIKORS INC.) is a body composition analyser for laboratory animals using DXA (Dual Energy X-ray Absorptiometry) with FAM BEAM 2 technology using a dual DR and DXA imaging model. This instrument provides accurate results of mineral content and density, bone, body composition (BMC, FAT, LEAN) of laboratory animals, in units of 0.001g without dissection, allowing serial evaluation of several laboratory animals after anaesthesia.
Proprietary software for generation and processing of visual stimuli for vision testing.
The Universitat de València has an extensive infrastructure in terms of equipment that makes it possible for research groups such as ours to carry out measurements of the most diverse types of functional performance, body composition, oxidative stress and metabolic risk, for example.
University department
Numerous international publications with impact show competence in developing reliable and valid measures in psychosocial and health contexts, including interdisciplinary intervention protocols.
Analysis of mutations in specific genes by highly sensitive technique (digital PCR) in liquid biopsy samples.
Sonifier.
Identification of markers (mutations in oncogenes) in solid tumours and monitoring of the evolution of the disease, detection of relapses or molecular progression of the disease in liquid biopsies.
Teaching documentation for training courses.
Configurable optical bench device for measuring the MTF.
SIMAX driving simulator. It has different training modules: one focused on road safety, in which students will be able to safely face risky situations, and another focused on efficient and ecological driving.
We have more than 200 Drosophila strains from stock centres or generated by the group.
Configurable perimeter to analyse visual mechanisms of magno, parvo and koniocellular origin, developed by researchers from the Optics Department in collaboration with INDO.
Isometric strength and fatigue analysis system.
The Lafayette Manual Muscle Tester Lafayette (MMT) is used to measure different types of grip strength and detect grip strength variations. The Lafayette MMT is ergonomically designed to fit the therapist's hand. 9 volt battery (included). The interactive menu allows the user to select a wide range of options such as data storage, test times (1-10 seconds), and choice of high and low threshold settings. In our interventions as we perform applications of strengthening exercise protocols it is essential to quantify the force performed by the subjects and specially to objectify it by means of the isometric maximal force value.
Handgrip (TKK 5101 Grip D; Takey, Tokio Japan) y Lafallete Manual Dynamometers (Nicholas Manual Muscle Tester, Lafayette Instruments, Lafayette, IN).
Gait corridor with a dynamometric platform for the analysis of gait, balance or any functional gesture of the lower limbs.
Dinascan/IBV Balance Platform (Biomechanics Institute of Valencia, Valencia, Spain), Wii Balance Board (Nintendo, Kyoto, Japan) and T-Plate (Medicaptures, France).
Electrochemistry Laboratory
System for the assessment of muscle activation, used for the characterisation of the sequencing of movement activation and the determination of fatigue.
8-channel electromyograph.
Electrophysiology unit used for neurons and pancreatic b-cells.
Electrotherapy and ultrasound units COMBI 500, COMBI 200, GLOBUS PREMIUM 400, CEFAR MYO 2, ENDOMED 982, ENDOMED 582, ENDOMED 484, TENSMED 911, CURAPULS 419, TERATHERM, Biofeedback MYO 420.
Anxiety assessment.
Se dispone de equipamiento para la realización de numerosas técnicas de Coprología Parasitaria.
Equipment and experience for the measurement of these behaviours: self-administration boxes, conditioned place preference boxes, open field, light/dark box, Barnes maze, Von Frey filaments and Hargreaves test.
Strength training and functional training equipment: Theraband balance trainer, Reebok Core Training, AM319S Seated Leg Press, M799 Freedom double pulley, Polar heart rate meters, Focus 308 cycloergometers and upper limb ergometers, AM311/DS Single Leg extension AC MOV LINE, Fitvibe Medical vibration platform, Domyos ST510 stepper.
Laboratory equipped with cookers, baths, refrigerators, plate and tube centrifuges, freezer and other small equipment to carry out the experiments to be performed.
Computerised programme for the evaluation of animal behaviour in different behavioural tests (aggression, social interaction, anxiety, learning, exploration...).
Automated ethopharmacological observation system.
Laboratory for the exploration of human driving behaviour using different technologies. It consists of a driving simulator, tests for measuring psychophysical and psychological aptitudes and a device for measuring visual campimetry.
Large space equipped with technology and research equipment in the field of sports performance (DEXA, isokinetic machines, ergometers - treadmill and bicycle - encoder and multipower for conditional assessment, etc.).
Perimeter with frequency doubling technology, for magnocellular channel analysis.
These cell lines are used for in vitro studies of FN function.
Modular system composed of binary pump, degasser, thermostated column compartment, automatic injector and high sampling frequency variable wavelength ultraviolet detector, controlled by data station, Agilent 1200 and 1260 series.
Flow cytometer with 2 lasers and 4-colour detection capability.
A 5-laser analysing cytometer for rapid measurement of morphological and functional parameters of large numbers of single cells suspended in a liquid medium. For this purpose, cells are initially labelled with fluorochrome-conjugated antibodies or fluorescent probes that bind to proteins located on the cell surface or inside the cell. The scattered light and fluorescence emitted by the markers as the cells are passed one by one through the different lasers allows simultaneous measurement of structural features and various parameters in each of these cells.
A three-laser analysing cytometer for rapid measurement of morphological and functional parameters of large numbers of single cells suspended in liquid medium. For this purpose, cells are initially labelled with fluorochrome-conjugated antibodies or fluorescent probes that bind to proteins located on the cell surface or inside the cell. The scattered light and fluorescence emitted by the markers as the cells are passed one by one through the different lasers allows simultaneous measurement of structural features and various parameters in each of these cells.
Equipment that determines and quantifies the fluorescence of fluorescent probes attached to different parts of both eukaryotic and prokaryotic cells, organelles, proteins. The emitted fluorescence is collected on different filters limited to a certain wavelength. Fluorescence quantification is associated with the cell parameter being measured, generating quantitative results such as fluorescence intensity, percentage of cell populations, cell count/ML.
Equipment that determines and quantifies the fluorescence of fluorescent probes attached to different parts of both eukaryotic and prokaryotic cells, organelles, proteins. The emitted fluorescence is collected on different filters limited to a certain wavelength. Fluorescence quantification is associated with the cell parameter being measured, generating quantitative results such as fluorescence intensity, percentage of cell populations, cell count/ML.
Fluorescence and phase contrast microscope fully equipped with video camera and software for imaging and video capture.
Inverted fluorescence microscope coupled to a computer with CellR and ScanR software to perform cytometry on plate cultured cells.
Fluorescence microscope dedicated to the acquisition of images of cell cultures and fixed histological and cytological preparations.
We are equipped with a Nikon microscope that has a digital camera and a fluorescence unit attached to it.
Fluorescence and luminescence plate reader.
Force platform with 4 piezoelectric sensors.
There is enough space in this laboratory to carry out patient evaluations and examinations. It is equipped with many of the resources specified above for this task.
System for the assessment of oxygen consumption and energy expenditure.
PCR thermal cycler.
We have personnel experienced in the generation and maintenance of organoids from tumour and normal patient tissue, as well as the facilities to do so. We also have experience in the molecular characterisation of these organoids (which recapitulate the characteristics of the patient from which they originate) and in the testing of drugs on them.
Principal Researcher: Pepa Castillo.
This device enables reactions to be carried out under flow conditions in hydrogenation processes where hydrogen is generated electrolytically.
Determination of monoamines, Dopamine, Serotonin and their metabolites in brain tissue.
HPLC chromatograph equipped with diode array detector and chiral stationary phase HPLC columns for the determination of the enantiomer ratio in chiral product samples.
Equipment consisting of oscilloscopes up to 4 GHz bandwidth and 3 GHz spectrum and vector analyser for the analysis of high speed/frequency signals.
High-performance platform for the digitisation of histopathological preparations comprising a high-performance scanner in bright light and fluorescence field with its accessories for the organisation, visualisation, analysis and transfer of Whole Slides Images (WSI).
Principal Researcher: Carolina Martínez.
High-performance liquid chromatography with electrochemical detection for quantitative analysis of dopamine and other neurotransmitters in dialysate samples obtained from different areas of the central nervous system using the in vivo microdialysis technique.
12-bit and 14-bit graphics cards, Bits++ and Visage, from Colour Research Systems, for specific vision tests requiring small changes in stimulus colour parameters (e.g., colour threshold and contrast sensitivity measurements).
Assessment of analgesia.
Genomic DNA and cDNA samples from a wide range of psychosis patients and healthy individuals.
Human tisstue from biopsies and surgical procedures in pathologies such as asthma, COPD, IPF, pulmonary hypertension, dermatitis and skin fibrosis.
Dome perimeter for white-white and blue-yellow threshold measurements.
This platform has various imaging scanners for experiments with small animals (mice and rats). These scanners can also be used to obtain images in solid biological samples.
Immunohistochemistry is a technique that allows the detection and quantification of different substances that act as antigens (receptors, neurons, etc.) in the fixed tissue by staining them. Our laboratory has all the necessary equipment to carry out this technique, as well as for tissue fixation.
The means are available to carry out numerous immunological and molecular techniques.
Equipment is available for the performance of numerous immunological and molecular techniques.
Microdialysis is a unique technique for monitoring the chemistry of the extracellular space in living tissue. In basic research it is mainly used to determine in vivo changes in endogenous compounds, drug delivery, PK/PD, bioavailability and bioequivalence. Our team has the necessary equipment for the development of in vivo microdialysis. It is performed on awake animals with freedom of movement. After implantation surgery and subsequent recovery of the animal, the animal remains in the stable cage until the time of analysis.
In-house resources are those that have been integrated into the laboratories of the Department of Paediatrics, Obstetrics and Gynaecology, as a result of subsidised projects or infrastructure investments by the UV.
Model that assesses emotional memory in mice
Experience in previous publications and consultancy work with multinational companies, by OTRI contract.
Material used for intervention, awareness-raising and re-education courses on the points-based driving licence.
Allows an accurate scanning of patients' dental arches, which helps to perform a diagnosis and/or work on the digital model itself.
Intravital microscopy for in vivo leukocyte interaction studies and measurements.
Flow chamber microscopy system for determination of leukocyte-endothelium interaction in vitro.
Software used to visualize CBCTS performed on patients. It allows their segmentation to visualize the dental arches. It also allows the measurement of three-dimensional cephalometry and of the respiratory tract.
These machines use a technology called isoinertial. It consists of a set of mechanisms that reinforce the eccentric part of the movement. Remember that many movements are made up of three phases: concentric (against gravity), isometric (where muscle contraction is maintained but without movement) and eccentric (slowing down the action of gravity). Well, it has been scientifically proven that emphasising the latter phase will help prevent injuries. The structural basis of these machines lies in flywheels or flywheels. When we apply force in the concentric phase, the machine stores the kinetic energy generated in various ways. This is returned in the eccentric phase and the subject will have to brake this inertia.
Quantification, collection and culture of human endothelial progenitor cells from peripheral blood.
Obtaining human endothelial cells from different vascular beds.
The mice strains that our group has generated are a tool for in vivo analysis of those processes that may be conditioned by the adhesion of interins to the FN.
Equipment that quantitatively determines the concentrations of one, several or many substances in a biological (serum, plasma, tissue or urine), food or environmental sample. This is achieved by chromatographic separation of the compounds present in the matrix to be studied, either by liquid chromatography or gas chromatography and their subsequent nebulisation with fragmentation to detect the components according to their molecular weight.
Mass spectrometer with TQ Detector triple quadrupole analyser. Metabolite quantification.
Digital imaging system (optical microscope).
The different laboratories that the Universitat de València has and that it makes available to the various research groups enable us to access the development of any type of functional, biochemical and psychological evaluation, this being possible in our case due to the contrasted multidisciplinary team that makes up this research group.
Research laboratory with 3 peninsulas of benches and side benches, including desks.
Research laboratory with fume hoods, safety cabinets for chemical storage, 2 bench peninsulas and side benches, including desks and two additional rooms.
Laboratory for organic synthesis, equipped with fume hoods with vacuum lines and inert gases for carrying out organic reactions under inert atmosphere under safe and hygienic conditions.
There is a space (physiotherapy laboratory for physical activity and sport) with a large amount of equipment for physical exercises or any intervention with weight training machines, weights, etc.
A laboratory is available for the performance of numerous immunological and molecular techniques.
The large equipment resources used are those of the UCIM of the Faculty of Medicine and Dentistry, including sequencers, qRT-PCR, confocal microscopy, flow cytometry, etc.
The Echinostoma caproni Life Cycle is maintained in our laboratory and other laboratories are asked to provide this material.
White light lamps for optical bench. Sources for UVA and UVB irradiation. Macbeth illumination booth with D65 and A illuminant. D65 illuminant simulator lamp.
Real-time thermal cycler (quantitative PCR).
Modular system composed of isocratic pump, quaternary pump, degasser, thermostatised column compartment, automatic injector and high sampling frequency diode array detector, controlled by Agilent 1200 series data station. Fluorescence and refractive index detectors are also available.
Modular system composed of isocratic pump, quaternary pump, degasser, thermostatised column compartment, automatic injector and diode array detector, controlled by Agilent 1200 series data station.
Modular system composed of quaternary pump, degasser, thermostated column compartment, automatic injector and UV detectors of variable wavelength and refractive index, controlled by data station, Agilent 1200 and 1260 series.
- Gambling addiction prevention programme for schools and the community. It consists of structured sessions with numerous audiovisual materials on gambling and gambling addiction. It aims to inform, raise awareness and change attitudes about gambling and gambling addiction in order to prevent addiction.
- It consists of test-retest assessment tools.
- It is a programme accredited by the Health Department of the Valencian Government.
Technique that allows the lyophilisation of biological material.
Solvent removal and drying of samples under mild conditions.
Software for the measurement of chromatographic peaks of various asymmetries, retention modelling for hydro-organic and micellar reversed-phase liquid chromatography, as well as optimisation of chromatographic methods. It contains numerous functions for retention modelling and chromatographic resolution. The software was commercialised on an international level.
Continuous physiological activity recording system for laboratory studies.
High resolution hybrid mass spectrometer and quadrupole time-of-flight analyser TRIPLETOF 6600+ and UHPLC (QTOF6600+).
The Massarray platform is responsible for the research study of biological samples through the fine mapping of DNA sequences and the analysis of methylation phenomena. With this equipment, dozens of DNA variants such as SNPs, insertions or deletions can be analysed in hundreds of samples in a short time with a high degree of precision and sensitivity. It is also possible to analyse somatic mutations such as those present in samples of cancerous origin. Finally, the degree of methylation of individual CpGs in short DNA sequences can be quantitatively quantified.
Massive DNA sequencing equipment based on sequencing by synthesis, using nucleotides labelled with fluorophores of different colours, and capturing images of the emitted fluorescence.
Measurement of spectral transmittance in vitro of lenses and ocular media (cornea, crystalline lens) extracted from patients or animals.
Procedure for the evaluation of the modulation transfer function of intraocular lenses in vitro, from which it is possible to estimate the optical quality of the lens.
Microbial characterisation using several approaches.
Microbial identification by essential gene sequencing.
The MALDI-TOF MS technique allows obtaining the characteristic protein profile of a microbial strain from the analysis of its ribosomal proteins, mainly.
- Deposit of strains of archaea, bacteria, filamentous fungi and yeasts up to risk group 3* according to the definition of Royal Decree 664/1997 of 12 May 1997.
- Deposit of phages of microbial strains up to risk group 2 according to the definition of Royal Decree 664/1997 of 12 May 1997.
The CECT has a public catalogue that includes more than 8000 strains of bacteria, archaea, filamentous fungi and yeasts. It also has the Mengovirus vMCO and will soon incorporate some phage strains.
Intravital microscopy system for determination of leukocyte-endothelium interaction in vivo.
NIKON DXM 1200C Digital Camera. NIKON E400 microscope. Progres CT3 USB Digital Camera; NIKON SMZ 745T Magnifier.
Experience in optical and confocal microscopy.
Room equipped with various pieces of equipment for cutting samples using different techniques. The equipment includes: vibratome, cryostat, paraffin/freezing microtome, paraffin/freezing sliding microtome, ultramicrotomes.
High frequency circuit and system design package.
Device widely used in thermal reactions, which allows drastic shortening of reaction times.
Incluye Módulo de incrustación en parafina calentado Leica EG1150, Placa fría para el sistema modular de incrustación de tejidos Leica EG1150 Micrótomo rotatorio semiautomatizado Leica RM2245 y Baño de agua para secciones en parafina Leica HI1210.
Experience in nucleic acid and protein separation and analysis techniques (electrophoresis, digestion, quantification, PCR, western blot, etc.), as well as cell analysis techniques (cell culture, immunohistochemistry, etc.).
Model that assesses spatial and reference memory in mice
Assessment of spatial memory.
Multiparametric protein analysis methodology (Luminex system).
The system allows a large number of analytes to be analysed in the same sample, with high sensitivity and reproducibility. The methodology used saves a great deal of time and minimises sample consumption.
Absorbance plate reader.
Benchtop Cytometer
We have extensive experience in the generation of mutant flies and analysis of different phenotypes (climbing ability, neurodegeneration, oxidative stress measurements, cuticle analysis, etc).
Spectrophotometer.
Laboratory located in the Department of Pathology, Faculty of Medicine and Dentistry, Universitat de València.
Retinograph for fundus evaluation in non-dilated pupil conditions with mydriatics.
Nuclear Magnetic Resonance (NMR) spectroscopy is defined as the study of molecules by recording the interaction of radiofrequency electromagnetic radiation with the nuclei of molecules located in an external magnetic field. It is a technique used to evaluate the biochemical content of living tissues, providing metabolic information complementary to the anatomical alterations that can be found in radiological studies.
Collection of probes for the manufacture of macroarrays. Macroarrays on nylon support with 5400 probes for S. cerevisiae genes.
Model that assesses recognition memory in mice
Use of different strategies (UAS-GAL4, RNA interference; CRISPR-Cas9) to obtain humanised models of diseases in Drosophila and study the phenotypes generated at biochemical, cellular, physiological and behavioural level.
Device for in vivo measurement of corneal aberrations.
Assessment of spontaneous motor behaviour and assessment of impulsivity.
This infrastructure consists of a box, also known as Skinner box, in which the animal is placed for a certain period of time and trained to perform a specific task (activate a lever) in order to receive a reward. It is a tool widely used in the field of psychology and addiction research.
Our group has extensive experience in the processing of samples for optical microscopy using various techniques depending on the variable to be analysed, such as paraffin, freezing or obtaining semi-thin sections. In addition to applying different types of staining, immunohistochemistry for the detection of a large number of antigens, autoradiographic techniques...
Equipment of the oral surgery unit on the first floor of the Lluis Alcanyís Foundation Dental Clinic.
System for testing the contractile response of isolated organ preparations (vessels, intestine, uterus...).
FDK 20 algometer, Somedic algometer, Von Frey monofilaments.
Collection of paired normal/tumour tissue samples obtained from patients with resectable stage (I-IIIA) non-small cell lung cancer, who have not received previous treatment. Cryopreserved tissue, DNA and RNA are available from all of them. The samples have associated clinical data.
Obtained with Informed Consent for Line of Research.
Tissue samples prepared for histology, western blotting, RT-PCR, and metabolite analysis.
Parallel Flow chamber for in vitro and ex vivo leukocyte interaction studies and measurements.
A laboratory is available for the performance of numerous parasitic coprology techniques.
Memory evaluation.
Automatic peptide synthesis.
Phage collection.
They are located on the fourth floor of the Faculty of Pharmacy. In the Pharmacognosy department, we have equipment for measuring the inflammatory process (plethysmometer, micrometer, etc.) as well as elisa and chemiluminescence readers, etc. We have the means to carry out Western blot techniques. Refrigerators and -80º C freezers. Tissue homogenisers. Cell counter. Histology equipment.
As an integral part of the Onco-Hematology Department, the main objective of the Clinical Trials Unit of the Onco-Hematology Department is to carry out clinical research at all stages of pharmacological development to meet the needs of society and the pharmaceutical industry. The Unit has all the human and material resources necessary to comply with current legislation and regulations applicable to clinical trials, and thus achieve quality clinical research.
To obtain genetically modified rodents, a characterisation (phenotyping) is required. It would include exploring behavioural and learning changes. Our laboratory has the experience needed to offer this service in the community. Including:
- Exploration test.
- Quantification of the locomotor activity and anomaly identification.
- Learning through classic conditioning (fear conditioning).
- Anxiety.
- Operant conditioning.
- Spatial memory.
- Olfactory sensitivity.
To obtain genetically modified rodents, a characterisation (phenotyping) which includes morphological alterations is required. Our laboratory has extensive experience in analysing in detail any alteration in the development or adult structure of the nervous system.
Space equipped with three classrooms and a common area to develop the group's own projects.
Physical space with teaching infrastructures for experimentation on learning processes.
Research area with functional and biomechanical assessment material with the possibility of kinematic and ultrasound studies.
The laboratory is divided into two areas: an open-plan area for group exercise and another equipped with apparatus and devices for therapeutic exercise.
Es tracta d'una plataforma que serveix per a determinar per una banda les cèl·lules sanguinis; rojos, blancs i plaquetes. En el cas de les blanques, també dona informació dels valors relatius i absoluts. Per l'altra banda, els analitzadors de bioquímica poden determinar una gran varietat de anàlits en sang, serum o plasma.
Equipment for the manufacture of density gradients and their subsequent fractionation used in the study of polysome profiling in cell extracts.
DNA extraction, whole genome sequencing (WGS), assembling, determination of quality parameters, genomic analysis...
Assessment of psychotic behaviour.
Monolayer and suspension cultures (3D cultures, organoids) obtained from tumour tissue samples from patients with resectable stage non-small cell lung cancer.
El programa de formació Empowering Coaching TM està basat en la teoria i en la investigació. Consisteix a formar als entrenadors en la creació de climes motivacionals que afavoreixen la diversió, la implicació esportiva i el benestar dels joves esportistes. Comprén tallers interactius (diapositives en power point, quadern de treball, vídeo-clips, jocs d'aprenentatge) i formació e-learning.
This group uses programming and tools to carry out an adequate acoustic and electromyographic recording of the voice, with sonometry, soundproofed rooms, computer programmes (PRAAT, VOCALAB), sound cards and microphones.
Assessment of mental health and psychological state in humans through questionnaires such as the State-Trait Anxiety Questionnaire (STAI), Perceived Stress Questionnaire (PSS), Resilience Questionnaire (CD-RISK), Beck Depression Questionnaire (BDI-II), etc.
Instruments for assessing personality, psychopathology and substance use.
Psychological intervention techniques for mental health and drug use.
- 1 State-Trait Anxiety Inventory (STAI).
- 1 Perceived Stress Scale (PSS-14).
- 1 AUDIT Scale (Alcohol Use Disorders Identification Test).
- 1 CAST Scale (Cannabis Abuse Screening Test).
Proprietary software for measuring chromatic and achromatic contrast sensitivity function, chromatic thresholds, coherence threshold, for monitors and colorimetrically characterised tablets.
Our laboratory is equipped with instruments to evaluate behaviour at cognitive, emotional and psychophysiological levels. This allows us to assess the cardiovascular (cardiac variability), electrodermal, respiratory and electromyographic responses.
Proteins used for coating materials and analysing cellular response.
A more sensitive and selective piece of equipment, faster in carrying out analysis and a solid service improver for the analysis of trace-level samples (pico-nanograms levels) of a great metabolite number in complex matrices such as biofluids and tissues, in an automated and relatively fast manner, generating a profile by multivariate statistical techniques, etc.
Laboratory adapted to the study of bone samples in the anthropological context that has, among other resources, a photographic laboratory, stereomicroscope BMS SL-40, Digital. stereomicroscope Motic DM-143-FBGG-B, mandibulometer, orbitometer, digital goniometer, etc. This laboratory allows the first phase of research to be carried out, which is complemented by the virtual morphology laboratory.
Given the experienced multidisciplinary team of the present research group, one of the primary objectives is the holistic understanding of the human being and for this a psycho-social analysis techniques will be incorporated, which will be complemented with the more eminently physiological ones and will enable to obtain an integral knowledge of the human being through motor skills as a common denominator.
Model that assesses emotionality and locomotor activity in mice
Real-time PCR is a technique that combines amplification and detection in a single step by correlating the PCR product of each cycle with a fluorescence intensity signal. They consist of a thermal cycler coupled to an optical system, which monitors the signal of the fluorophores used to detect the amplified product. Because the fluorescence of the fluorophores increases as the product is amplified, the amplification and detection processes are combined in a single step.
Immersion coolants for controlled low-temperature reactions.
Lector òptic d'enquestes.
Consolidated group with proven experience in epidemiology and environmental health research. Bibliographic database with more than 6000 references.
Research laboratories equipped with specially configured computers for research in DNA methylation analysis and Distributed Virtual Enviroments.
The Faculty of Psychology and Speech Therapy has laboratories for the research groups that are requested according to their needs.
BioGrid II is a robot for the fabrication of macroarryas on nylon support or for the copying of collections of microorganism strains deposited on microtitre plates.
DNA concentrator.
Its aim is to provide the IIDL researchers with the infrastructure necessary for the mapping associated with their research projects using Geographic Information Systems (SIG)
Sorvall centrifuge with SLA3000 SuperLIte® and SS34 rotors.
Software for statistical data analysis.
Sample preparation for HPLC, gas chromatography, ELISA or enzyme assays.
Our group has extensive experience in processing samples for electron microscopy including fixing, embedding and obtaining ultra-thin sections, as well as analysing a wide range of samples with the electron microscope.
System design for the detection of different species.
Equipment that determines and quantifies the fluorescence of fluorescent probes attached to different parts of both eukaryotic and prokaryotic cells, organelles, proteins. The emitted fluorescence is collected on different filters limited to a certain wavelength. Fluorescence quantification is associated with the cell parameter being measured, generating quantitative results such as fluorescence intensity, percentage of cell populations, cell count/ML.
The equipment has a cell separation system allowing the physical separation of a given population with different levels of purity. It allows separation under sterile conditions.
Collection of blood samples (serum, plasma, leukocyte fraction, platelets) from cancer patients prior to initiation of treatment or progression. The samples have associated clinical data.
Obtained with Informed Consent for Line of Research.
Test room with driving simulator.
Assessment of the reinforcing effect of drugs.
Perceptual training programme to improve the visual function of amblyopic people.
A unique and versatile place for training in research and excellence in the field of social sciences. Equipped with state-of-the-art infrastructures and equipment, this laboratory is divided into three rooms, dedicated to the application of quantitative and qualitative social research techniques in all phases of the research process (collection, registration and data and information analysis)
Feasibility of social systems through mathematical modelling.
Software for the design of implicit memory assessment tests.
System for collaborative music creation and sound production, automated or not.
This unit focuses its interest in developing tools and resources for the speech therapy care of people with neurological disorders that involve communication, oral and written language, speech and eating disorders (dysphagia), in its preventive aspect, in the evaluation, diagnosis, rehabilitation and research.
Blood pressure recording in humans.
Server with METBA System (remote monitoring and evaluation system) and Tests (online test presentation system) and video recording system.
The UV Statistics Unit works with experts in the use of computer equipment and specific software. The main software used for data analysis is the free R Software.
UV-visible absorbance spectroscopy, circular dichroism and fluorescence.
Electromyography is a test widely used in medical science to assess the health of the neuromotor system, among many other uses it can have for the development of biomedical projects. The electromyograph is equipment used to activate, record, conduct and expose nerve and muscle action potentials for the purpose of assessing nerve and muscle function. Surface EMG signals (EMGS) are essentially a one-dimensional pattern, so any signal processing technique for feature extraction and pattern recognition can be applied to this type of signal. The information extracted from EMGS signals is selected in such a way as to minimise error in the control of myoelectric prosthesis systems. In neuromuscular pathology, the starting point is always a fundamental physiological concept: the motor unit (MU) (Lidell and Sherrington, 1925).
By means of this technique it is possible to measure the electromyographic activity of the muscles related to phono-articulation, and it provides objective dates of activities related to voice production, speech, singing, swallowing and chewing, most of which are of interest to the people who form part of this research group.
A system for determining the affinity of a drug for its drug target by binding radioligands.
Laboratory with high-tech biomechanical tools and an important team of psychiatrists and psychologists making functional and neurocognitive assessments by offering three services:
- Neurocognitive Assessment: clinical and comprehensive neurocognitive assessments are carried out and the affected people as well their relatives are treated in order to guarantee a quality and independent life.
- Biomechanical Assessment of Human Functions: it provides objective and quantitative information on functional repercussions of a pathology in a person’s activities and functions, becoming an additional tool for health workers in the control of functional deficiencies of the musculoskeletal system.
- Gaze monitoring system (TOBII): it allows the recording and analysis of the gaze which can be used as an assessment and rehabilitation tool. Providing information in various fields of knowledge as an interpretation of human behaviour.
Bioimpedance scale.
Chemi-Doc XRS gels documentation system (Bio-Rad). Floor and tabletop ultracentrifuges. Real-time PCR CFX96 Touch System (Bio-Rad). Fluorescence microscope. Image contrast microscope and digital video camera-imaging system. ELISA microplate readers. Mono and two-dimensional electrophoresis systems. Refrigerated centrifuges, freezers and coolers; orbital incubators; electroporator; sonicator; autoclaves and water purification systems.
Histopathology. Microscopy. Fluorescence. Morphometry. Laser dissection microscopy Genetics. Western blotting. Molecular biology. Genomics. Proteomics. Cell cultures. Metabolomics. Karyotypes.
TecnoTest is a tool that has two main objectives:
- Screening or early detection of technological addictions (video games, mobile, social media) and gambling.
- Prevention guidelines.
It consists of 24 items, in which there are 12 items (three for each of the four addictions mentioned) that discriminate between those who make appropriate use of technologies or play without problems, and those who have a problem of addiction to gambling or technology. A score on all three items for an addiction is related to a probable addiction problem (gambling, video games, mobile or social media), which requires further assessment and probably specialised intervention. In the event that the person scores 1 or 2 items, specific guidelines will be required to prevent the onset of addiction.
This survey has been developed at the Universitat de València.
Dynamic test for the assessment of tendon injuries by means of specific exercises.
Tensiomyography (TMG) is an innovative and simple technique that allows us to detect and analyse separately the contractile properties of superficial muscles. It is a diagnostic method that works by observing the geometric changes that occur in the muscle belly when the muscle contracts. The purpose of TMG is the continuous monitoring of the state of the muscle fibres and the surveillance of their separate evolution, which will allow us to obtain selective information on the measured muscles.
Assessment of learning and memory.
Thermal imaging camera FLIR E60bx (FLIR Systems, Wilsonville, OR).
Decelluralisation of tissues, cell culture, isolation and characterisation of stem cells.
Permet l'escanejat i l'adquisició de volum especifique del cap del pacient i que genera dades en 3D, amb utilització de dosi de radiació moltes vegades menor que la dosi utilitzada pels tomògrafs mèdics.
This is an O2-CO2 gas analyser with air flow and two-animal switch. It contains: a software platform for metabolism, "respiratory metabolism" extension of the Metabolism software, single line Treadmill for mouse with shock, Calorimetry Runner for the treadmill, Rat/Mouse tray, Two Calorimetry lids for food and drink rats, Calorimetry Feeder/Drink, 100mL bottle for Oxylet system, Rat grid floor, Mouse grid floor. This equipment has been supervised by the specialist technician Javier Cuenca.
Driving simulator to perform different tests related to truck driving.
Experimental behavioural room and infrastructure of the Central Research Unit.
Ultrasonic Densitometer Sonost 3000 (OsteoSys Co., Ltd. Seoul, Republic of Korea).
Edan U50 ultrasound machine with 10-15 Mhz probe (Edan Instrument Inc., Nanshan Shenzhen, China), logicC5 ultrasound machine (General Electric), SAMSUNG HS30 (SAMSUNG MEDISON CO., LTD).
The ultrasound scanner is an electromedical medical device used to perform ultrasound scans, which takes advantage of high-frequency sound waves to generate image sequences of organs and formations within the body. It is used in our area to determine certain anatomical aspects such as muscular lesions, alterations or other aspects that cannot be quantified by sight.
Collection of instruments and material sources of science and technology.
Virtual morphology laboratory, headed by research group member Dr. Markus Bastir, for the application of different methods and techniques for quantitative research in 3D morphology using computerised (virtual) techniques.
The laboratory is equipped to allow the digitisation of anatomical objects by means of a scanner, either surface (laser, structured light) or computed tomography (clinical CT, or microCT) to obtain a virtual 3D model of the object under study, 3D quantification by measurement of landmarks and semilandmarks to obtain quantitative morphology data, statistical analysis of the quantitative data by geometric morphometry (Procrustes analysis), virtual modelling, and rapid prototyping of all these virtual models by 3D printing in different sizes (original scale, larger or smaller) for study, scientific communication or also for museum purposes.
In the Faculty of Psychology, teaching laboratories unit (Stage 3), we have complete equipment for the dispensing of treatments (EPR) using virtual reality (44' TV, kinect devices, adapted computer, etc.).
Laboratory of Psychophysics of Vision and Visual Perception, located in the Faculty of Physics and attached to the Department of Optics and Optometry and Vision Sciences.
cognitive recording of memory in humans
Protein detection, DAT, SERT.
Western Blot is a widely used analytical technique for the study of proteins. This method allows the detection of a single protein within a biological sample. The specificity of Western Blot is achieved by using an antibody that recognises and binds to a single epitope of the protein of interest. The Western Blotting technique can estimate the size of a protein, confirm the presence of post-translational modifications such as phosphorylation, and be used to quantitatively compare protein levels between samples.
This system can be used to irradiate models in vivo (rats and mice) and in vitro (cell cultures). In addition, the integrated imaging system (OptiMAX) can provide bioluminescence imaging, 2D X-ray imaging and radioisotope imaging.
Collection of plasmids with different yeast genes.
Collections of wild-type and mutant strains of S. cerevisiae, S. pombe and C. albicans and E. coli transformed with recombinant plasmids.
Fluorescence microscope
In IDOCAL laboratory. Ability to measure physiological reactions of the individual (dermal response, heartbeat, sweating, etc.) to the presentation of various stimuli (brands, packaging, advertisements, etc.), in order to measure their effectiveness.
