University of Valencia logo Logo Scientific Technological Offer Logo del portal

2 high-performance digital oscilloscopes (with mixed analogue/digital inputs) ; 1 function generator; 2 dual power supplies ; 1 hand-held multimeter

Devices and equipment for electronic project development.

AMS Psychophysiological Recording System

Continuous physiological activity recording system for field studies, since it is an ambulatory system.

Accelerometers

Triaxial accelerometers.

Acquisition system and biosignal processing
  • Multi-Channel GTEC biosignal amplifier for ECG, EEG, EOG and biomedical signal aquisition.
  • Multi-Channel Whole-Head EEG acquisition.
  • Wireless biosignal amplifiers for EOG.
  • NATIONAL INSTRUMENTS Acquisition Cards and Signal Digitizing.
Activation complexity maps

Activation maps during ventricular fibrillation are constructed from the analysis of two-second time windows. Each map is classified into three categories according to its complexity: low (type I), comprising a single broad wavefront with no conduction block or areas of slow conduction; intermediate (type II), consisting of two wavefronts or a wavefront with areas of conduction block or slow conduction; and high (type III), comprising three or more wavefronts associated with areas of slow conduction and conduction block. The degree of complexity is expressed as a quantitative variable using the formula: CI = (number of type I maps x 0.1 + number of type II maps x 1 + number of type III maps x 2) / total number of activation maps.

Advanced Endodontic Microscopic Training Centre

Laboratory equipped with microscopes for endodontic practice and research.

Aggregometry MOD. 590-2D (CHRONO-LOG)

Platelet aggregation measurement system (whole blood or PRP).

Agilent 2100 Bioanalyzer

The Agilent 2100 Bioanalyzer is a microfluidic-based platform designed for sizing, quantification and quality control of DNA and RNA by small-chip electrophoresis in a single instrument. Results are obtained in a short time in an automated way, directly in digital format.

The miniaturisation of analytical instruments offers numerous advantages over conventional techniques. These include improved data accuracy and reproducibility, reduced analysis times, minimal sample consumption and improved automation and integration of complex workflows.

Analysis of sport technique and/or physical activity 3

The research team has the necessary resources to develop individualised analyses and reports for athletes and/or people who wish to carry out an evaluation of the physical activity practised (walking, running, etc...), with specific instruments and qualified personnel.

Analysis of sports practice

Research unit for the analysis of sports practice.

Animal housing and experimental operating theatres of the Central Research Unit (UCIM) of the Universitat de València

The group maintains a direct relationship with the Central Research Unit of the Faculty of Medicine and Dentistry (UCIM) where the housing and training of the rabbits is carried out. It also has access to the experimental operating theatres necessary for the execution of the experimental phase of the chronic infarct line and inhibition of histone deacetylase enzymes (IDAH).

Animal models of anxiety

Scientifically validated elevated maze, plus-maze and zero-maze tests as suitable animal models for anxiety assessment.

Animal models of learning

Scientifically validated object recognition, passive avoidance and water maze tests as suitable models for learning assessment.

Array platform: expression and cytogenetics

The Array platform, designed by Affymetrix, provides a holistic study of organisms from the perspective of systems biology, a better understanding of biological properties and interactions as a whole. This technology provides the flexibility to study a specific subset of genes of interest or to be able to focus on the study of the genome at a global level in order to understand and define in depth the complex mechanisms and networks that underlie biological processes and diseases. 

Assessment of optical quality and visual function in patients with pathologies

Modulation transfer function and contrast sensitivity measurements. Tests to detect colour vision defects (anomaloscope, pseudoisochromatic tests, sorting tests, measurement of colour thresholds). Perimetry (standard, blue-yellow, frequency doubling and flicker).

Audiovisual recording equipment for the recording and monitoring of psychological treatments

At the Faculty of Psychology, in the teaching laboratory unit (Stage 3), we have installed, at the expense of our projects, complete equipment for the video recording and reproduction of the evaluation, treatment and experimental sessions that we carry out with people affected by OC spectrum disorders and the general population.

Beckman Coulter Z2 Cell and Particle Counter

Automatic cell counter and size analyser.

Biomechanics Laboratory (UV, Blasco Ibáñez Campus, Valencia)

Biomechanics laboratory equipped with instruments and technology for the biomechanical analysis of physical activity and sport. Faculty of Physical Activity and Sports Sciences. Blasco Ibáñez Campus, Universitat de Val

Biomechanics Laboratory (UV, Ontinyent Campus)

Biomechanics laboratory equipped with instruments and technology for the biomechanical analysis of physical activity and sport. 

Faculty of Physical Activity and Sport Sciences. Ontinyent Campus, Universitat de València.

Biomechanics Laboratory

Large space equipped with technology and research material in the field of biomechanics applied to improving sports performance and health.

Blown glass

We work with laboratories that require borosilicate glass instruments:

  • Table-top torch.
  • Hand torch.
  • Lathe.
Body composition monitor

Tanita BF350 scale (TANITA Corporation, Arlington Heights, IL, USA).

CANTAB

Neuropsychological evaluation system that includes memory, attention, executive functions and social cognition tests, among others.

CAVE type inverse display system

Individual inverse visualisation system with 3D location systems and projection on three side screens and the floor.

CED Unit

Signal acquisition system.

COLORCAL colorimeter

Contact colorimeter for colour measurement on screens (Cambridge Research Ltd.).

Cadence design software

Assisted electronic design package for the design of integrated and printed circuits.

Calculation farm "Dresden"

Parallel computing server farm with capacity for 80 processors.

Calculation of driving speed

The conduction velocity of the electrical impulse during ventricular fibrillation is the ratio between the distance between two electrodes located in a direction perpendicular to the isochrones and the difference between their activation times (average of 5 determinations). Only maps in which both the input and output wavefronts are identified at the edges of the activation maps are used to determine the velocity. The wavelength of the activation process during VF is calculated as the product of velocity and refractoriness.

Calculation servers
  • Linux server 8 Core Intel Xeon X5450 3.0 GHz 16GB RAM 1.5TB hard disk in RAID5.
  • Linux server 8 Core Intel Xeon X5355 2.66 GHz 32GB RAM 2.5TB hard disk in RAID5
  • Linux server 16 Core Intel Xeon E5530 2.40 GHz 72 GB RAM 2.5TB hard disk in RAID5.
Calibrated CRT monitors for vision experiments

Various 21-inch CRT monitors (Sony and Mitshubisi), colourimetrically characterised, computer-controlled, for psychophysical measurements and perceptual training.

Capillary Electrophoresis Sequencing System

The equipment allows DNA sequencing by the Sanger method and fragment size determination.

Capillary pumps of liquid chromatography, conventional chromatography and nanochromatography. Detectors: fluorescence, diode array, electrochemical, chemiluminescence and masses
Cell Culture Unit A

Cell culture unit with class I laminar flow cabinet.

Cell Culture Unit C

Cell culture unit with class II laminar flow cabinet and IG750 hypoxia incubator (JOUAN).

Cell Culture Unit D

Cell culture unit with class II laminar flow cabinet.

Cell Cultures Unit B

Cell culture unit with class II laminar flow cabinet and INVIVO2 400 hypoxia chamber (RUSKINN).

Cell culture and conventional cytogenetics laboratory

Cell culture and conventional cytogenetics laboratory: equipped with CO2 incubators, phase contrast microscopy and laminar flow chambers.

Cell-free protein expression systems

In vitro transcription/translation systems.

Characterisation of biomaterials

Microscopic, structural and morphological analyses. Biocompatibility and bioactivity studies of dental materials.

Chemoluminiscence Detection Imager (LAS3000, Fujifilm)

Detector and chamber for chemiluminescence and fluorescence (Western blotting and DNA electrophoresis).

Chromatic filters

Interferential filters tuned to different visible wavelengths. Coloured lenses for use as optical aids for individuals with dyschromatopsia.

Cibertec Large inhalation anaesthesia equipment, animal operating theatre

Equipment that allows the induction and maintenance of rodents under anaesthesia for the performance of surgical procedures. Anaesthesia should always be complemented by an adequate analgesia protocol.

Circular Dichroism Spectrometer JASCO J-810

Circular Dichroism Spectrometer.

Clinical Research Laboratory in Physiotherapy

Open-plan laboratory for clinical research, enabling physiotherapy assessments and interventions to be carried out.

Cognitive assessment through questionnaires in humans

Assessment of cognitive status in humans through questionnaires such as Trai Making Test (TMT A and TMT B), Weschler Memory Scale, Mini-Cog, Mini-Mental State Examination (MMSE), etc.

Collection of fibroblast cell lines established from tumour and fibrotic tissue

Collection of fibroblast cell lines established from tumour and fibrotic tissue.

Collection of lung carcinoma cell lines established from tumour tissue

Collection of lung carcinoma cell lines established from tumour tissue

Collection of tumour tissue samples from lung cancer patients

Collection of tumour tissue samples from lung cancer patients.

Collection of tumour tissue samples from patients with pulmonary fibrosis

Collection of tumour tissue samples from patients with pulmonary fibrosis.

Colorimetric characterisation of image capture and display devices

Evaluation of the activity and spatial homogeneity of display devices. Colourimetric characterisation of display devices and characterisation by means of physical, polynomial models or LUT tables.

Colorimetry

Colorimeters and spectrophotometers for clinical and laboratory studies of dental colour.

Colorlab

Matlab library for colour spaces, vision models, control and stimulus generation, developed by different members of the Optics Department, including members of our group.

Colour vision test batteries

Anomaloscope. Ishihara test. Sorting tests (D15, Lanthony, Farnsworth-Munsell 100-tone). Threshold measurement test (Cambridge Colour Test. Optopad).

Computing Cluster Servers

The team has a cluster of five servers: geeitema.uv.es, bayesiano.uv.es, mebospuma.uv.es, valimba.uv.es and gdisco.uv.es. The gdisco server is used to centralize user information. The geeitema server is the server that hosts the website and various management services. And the bayesian, mesbospuma and valimba servers are used for intensive computing. The latter servers are the ones that have the software and tools necessary to perform all the calculations required for our research.

 

Computing cluster

High-performance distributed computing infrastructure to perform all kinds of multi-scale simulations.

Confocal Microscope

Confocal fluorescence scanning microscope.

Corneal topographer

Device for point-to-point measurement of corneal curvature by means of placido discs.

Corneas and crystalline lenses

Corneas and crystalline lenses from deceased donor and various animal species (pig, rabbit, horse, chicken, sheep).

Creative Robotics System Llec Mindstorms

Five robotics systems are available to give courses on these topics.

Demo_estimuls

Proprietary software for generation and processing of visual stimuli for vision testing.

Digital Sonifier (BRANSON)

Sonifier.

Digital ddPCR

Identification of markers (mutations in oncogenes) in solid tumours and monitoring of the evolution of the disease, detection of relapses or molecular progression of the disease in liquid biopsies.

Documents for theoretical and practical classes

Teaching documentation for training courses.

Double-pass device for optical quality assessment

Configurable optical bench device for measuring the MTF.

Dual modulation ATD perimeter

Configurable perimeter to analyse visual mechanisms of magno, parvo and koniocellular origin, developed by researchers from the Optics Department in collaboration with INDO.

Dynamometers

Handgrip (TKK 5101 Grip D; Takey, Tokio Japan) y Lafallete Manual Dynamometers (Nicholas Manual Muscle Tester, Lafayette Instruments, Lafayette, IN).

Dynamometric platforms

Dinascan/IBV Balance Platform (Biomechanics Institute of Valencia, Valencia, Spain), Wii Balance Board (Nintendo, Kyoto, Japan) and T-Plate (Medicaptures, France).

Electrical stimulation system

Stimulation system: Grass® electrodes and stimulator, model S88 (Grass Instruments Inc., Quincy, MA, USA) fitted with a stimulus isolation unit (model SIU5, from the same company). The stimulator can deliver current pulses and control parameters such as stimulation frequency, number, intensity and duration of stimuli.

Electromyograph

8-channel electromyograph.

Electrophysiology Unit

Electrophysiology unit used for neurons and pancreatic b-cells.

Electrotherapy equipment

Electrotherapy and ultrasound units COMBI 500, COMBI 200, GLOBUS PREMIUM 400, CEFAR MYO 2, ENDOMED 982, ENDOMED 582, ENDOMED 484, TENSMED 911, CURAPULS 419, TERATHERM, Biofeedback MYO 420.

Equipment for therapeutic exercise

Strength training and functional training equipment: Theraband balance trainer, Reebok Core Training, AM319S Seated Leg Press, M799 Freedom double pulley, Polar heart rate meters, Focus 308 cycloergometers and upper limb ergometers, AM311/DS Single Leg extension AC MOV LINE, Fitvibe Medical vibration platform, Domyos ST510 stepper.

Ethological assessment of animal behaviour

Computerised programme for the evaluation of animal behaviour in different behavioural tests (aggression, social interaction, anxiety, learning, exploration...).

FCAFE Performance Laboratory

Large space equipped with technology and research equipment in the field of sports performance (DEXA, isokinetic machines, ergometers - treadmill and bicycle - encoder and multipower for conditional assessment, etc.).

FDT perimeter

Perimeter with frequency doubling technology, for magnocellular channel analysis.

FN-expressing cell lines with alterations in strategic integrin and syndecan4 adhesion sites

These cell lines are used for in vitro studies of FN function.

Flow Cytometer (FACSCalibur, BD)

Flow cytometer with 2 lasers and 4-colour detection capability.

Flow cytometer analyser - BD LSR Fortessa X-20

Equipment that determines and quantifies the fluorescence of fluorescent probes attached to different parts of both eukaryotic and prokaryotic cells, organelles, proteins. The emitted fluorescence is collected on different filters limited to a certain wavelength. Fluorescence quantification is associated with the cell parameter being measured, generating quantitative results such as fluorescence intensity, percentage of cell populations, cell count/ML.

Fluorescence microscope (Olympus), coupled to static cytometry.

Inverted fluorescence microscope coupled to a computer with CellR and ScanR software to perform cytometry on plate cultured cells.

Fluoroskan Ascent FL (Thermo Labsystems)

Fluorescence and luminescence plate reader.

Force platform

Force platform with 4 piezoelectric sensors.

Free or subscription-based corpus programmes

Use of various software tools with which the tasks are carried out and which must be evaluated. There are a large number of them, both freely available and subscription-based, as well as through platforms. In all cases we already have the fundamental ones.

Freeze-dryer

Freeze-drying is a process in which the product is frozen and subsequently introduced into a vacuum chamber to perform the separation of water by sublimation. In this way, water from the solid to the gaseous state is removed from the environment without going through the liquid state. To speed up the process, freeze-sublimation cycles are used to practically eliminate all the free water contained in the original product, while preserving the molecular structure of the lyophilised substance.

Frequency-domain analysis of ventricular fibrillation

We use Welch's method to obtain the power spectrum of the signals recorded with each electrode. The periodogram is calculated for the first four seconds of each signal (4096 points, 1 kHz sampling rate), fragmenting the recordings into 8 segments with 50% overlap and using the Hamming window. The mean dominant frequency (FD) in the scanned area is determined by averaging the maximum peak power spectral density between 5 and 48 Hz at each electrode. The mean spectral concentration (EC) is also calculated by averaging the percentage of the total energy contained in the FrD range ± 0.5 Hz in each recording channel.

GPU Cluster

High-performance (vector) computing infrastructure to be able to perform all types of multi-scale simulations. 

Gas Chromatograph (GC): Agilent 6890N (equipped with chiral columns)

It helps in the analysis of solutions. Agilent offers customized, pre-tested systems and solutions for specific chemical analysis application. This GC has all the flexibility and performance needed for research and method development in any industry. It is also rugged and reliable—perfect for routine methods that require multiple columns or valves, specialty inlets or detectors, or a broad temperature range. This GC system offers proven, fourth-generation electronic pneumatics control (EPC) that keeps pressure and flow setpoints constant from run to run. 

Gas chromatrograph - Mass spectrometer

The chromatograph is used for the identification of non-polar and volatile molecules. It is a conventional equipment with quadrupole and NIST library that allows to identify a wide variety of compounds, including polycyclic aromatic hydrocarbons.

GeneAmp PCR System 2400 (Perkin Elmer)

PCR thermal cycler.

Generation of organoids from patient cells as a tool for disease characterisation and a platform for drug testing

We have personnel experienced in the generation and maintenance of organoids from tumour and normal patient tissue, as well as the facilities to do so. We also have experience in the molecular characterisation of these organoids (which recapitulate the characteristics of the patient from which they originate) and in the testing of drugs on them.

Principal Researcher: Pepa Castillo.

Genomic and transcriptomic analysis system for single cells

Platform to carry out transcriptomic studies in the single cell field, allowing the study of transcriptomic and phenotypic variability among thousands of cells based on single cell RNA.

HPLC equipment with fluorescence detector and an autosampler

High performance liquid chromatography (HPLC) equipment is used to separate the components of a mixture based on different types of chemical interactions between the analysed substances and the chromatographic column. The compound passes through the chromatographic column via the stationary phase (usually a cylinder with small rounded particles with certain chemical characteristics on its surface) by pumping liquid (mobile phase) at high pressure through the column. The sample to be analysed is introduced in small quantities with an autosampler and its components are differentially slowed depending on chemical or physical interactions with the stationary phase as they advance through the column. These components are quantified by a fluorescence detector that detects only those substances that emit fluorescent light. It’s used for naturally fluorescent compounds or fluorescent derivatives.

HPLC equipment with ultraviolet detector and an autosampler

High performance liquid chromatography (HPLC) equipment is used to separate the components of a mixture based on different types of chemical interactions between the analysed substances and the chromatographic column. The compound passes through the chromatographic column via the stationary phase (usually a cylinder with small rounded particles with certain chemical characteristics on its surface) by pumping liquid (mobile phase) at high pressure through the column. The sample to be analysed is introduced in small quantities with an autosampler and its components are differentially slowed down depending on chemical or physical interactions with the stationary phase as they advance through the column. These components are quantified by an ultraviolet detector which responds to light absorbing substances.

Haematology and Biochemistry Platform

This platform can determine the type of blood cells (red, white and platelets). For white blood cells, it also provides information on relative and absolute counts. On the other hand, it allows biochemical analysers to determine a wide range of analytes in blood, serum and plasma.

High frequency/speed signal measurement equipment

Equipment consisting of oscilloscopes up to 4 GHz bandwidth and 3 GHz spectrum and vector analyser for the analysis of high speed/frequency signals.

High resolution optical mapping system

Optical mapping techniques allow the recording of simultaneous voltage and calcium variations characterising the action potential as well as calcium transients with high spatial resolution. Dual voltage and calcium recording is used to characterise transmembrane potentials and calcium variations in the same viewing plane. A light source consisting of a triplet of LEDs and a camera with high-speed electron multiplier charge-coupled charge coupled device (EMCCD) imaging sensors is used. The lens system and the switching circuit allow the recording of voltage and calcium parameters at the same time with the same camera. We record transmembrane voltage using a voltage-dependent fluorescent compound (di-8-ANEPPS) while Ca2+ is recorded with fura-4F. By obtaining phase maps and singularities we can characterise activation patterns and the degree of organisation of complex arrhythmias.

High-performance brightfield and fluorescence scanner for immunohistopathological preparations

High-performance platform for the digitisation of histopathological preparations comprising a high-performance scanner in bright light and fluorescence field with its accessories for the organisation, visualisation, analysis and transfer of Whole Slides Images (WSI).

Principal Researcher: Carolina Martínez.

High-resolution graphic cards

12-bit and 14-bit graphics cards, Bits++ and Visage, from Colour Research Systems, for specific vision tests requiring small changes in stimulus colour parameters (e.g., colour threshold and contrast sensitivity measurements).

Histopathology Laboratory

Histopathology Laboratory: automated parts processors and slide microtomy.

Humphrey SAP-SWAP perimeter

Dome perimeter for white-white and blue-yellow threshold measurements.

Imaging platform: PET/CT-MRS-3T/IVIS-X5

This platform has various imaging scanners for experiments with small animals (mice and rats). These scanners can also be used to obtain images in solid biological samples.

Immunohistochemistry laboratory

Immunohistochemistry Laboratory: histochemical and immunohistochemical techniques. Instruments: sliding and freezing microtomy, microwave oven, balances, pH meters, various reagents, Beecher TMA tissue matrix processing equipment and automated immunostaining system (Dako Autostainer LINK48).

Inverted Microscope NIKON ECLIPSE TE 2000-S

Flow chamber microscopy system for determination of leukocyte-endothelium interaction in vitro.

KALEO system

System for the characterisation and optical quality control of intraocular lenses using optical interferometry techniques.

KI mice strains

The mice strains that our group has generated are a tool for in vivo analysis of those processes that may be conditioned by the adhesion of interins to the FN.

LEICA DMD108 Microscope

Digital imaging system (optical microscope).

Laboratory 01 (Department of Pharmacology, Faculty of Medicine and Dentistry)

Research laboratory with 3 peninsulas of benches and side benches, including desks.

Laboratory 0E2 (Department of Pharmacology, Faculty of Medicine and Dentistry)

Research laboratory with fume hoods, safety cabinets for chemical storage, 2 bench peninsulas and side benches, including desks and two additional rooms.

Laboratory of Experimental Cardiac Electrophysiology (1) of the Department of Physiology of the Faculty of Medicine and Dentistry at the Universitat de València

Laboratory 358. Campus 1. Building 6. Ground floor. It has the necessary equipment for electrophysiological studies with high-resolution electrical mapping of cardiac electrical activity: Langendorff type metabolic support systems for isolated heart, stimulation systems and recording of cardiac electrical activity.

Laboratory of Experimental Cardiac Electrophysiology (2), Department of Physiology, Faculty of Medicine and Odontology, Universitat de València

Laboratory 359. Campus 1. Building 6. Ground floor. It has the necessary equipment for electrophysiological studies with optical mapping of cardiac electrical activity. Langendorff type metabolic support systems for isolated pig heart, stimulation systems and optical mapping of cardiac electrical activity.

Laboratory of Experimental Cardiac Electrophysiology (3), Department of Physiology, Faculty of Medicine and Odontology, Universitat de València

Laboratory 403. Campus 1. Building 6. Ground floor. Equipment available necessary to develop electrophysiological studies in cellular cultives.

Langendorff isolated pig heart perfusion systems

Langendorff type metabolic support system for isolated pig heart specially designed to perform electrophysiological studies with high resolution mapping techniques (electrical or optical procedures).

Langendorff-type isolated rabbit heart perfusion systems

Langendorff type metabolic support systems for isolated rabbit heart specially designed to perform electrophysiological studies with high resolution mapping techniques (electrical or optical procedures).

Laser

He-Ne and diode lasers, anti-vibration tables and complementary optical equipment. Specific image analysis software.

Light sources

White light lamps for optical bench. Sources for UVA and UVB irradiation. Macbeth illumination booth with D65 and A illuminant. D65 illuminant simulator lamp.

LightCycler (Roche Applied Science)

Real-time thermal cycler (quantitative PCR).

Liquid chromatograph - Mass spectrometer

Equipped with ultra-high resolution liquid chromatography (UHPLC) equipment, automatic injector for 100 samples and triple quadrupole tandem mass spectrometer that is connected by means of an electrospray source.

MAPTECH electrical activity mapping system

Cardiac electrical activity mapping system (MapTech, Waalre, The Netherlands) for acquisition, digitisation and processing of ventricular electrographic signals: 256 channels, 50-300 gain, 1-400 Hz bandwidth, 1 kHz channel sampling rate and 12-bit resolution.

MP150 Psychophysiological Recording System

Continuous physiological activity recording system for laboratory studies.

Massarray Platform

The Massarray platform is responsible for the research study of biological samples through the fine mapping of DNA sequences and the analysis of methylation phenomena. With this equipment, dozens of DNA variants such as SNPs, insertions or deletions can be analysed in hundreds of samples in a short time with a high degree of precision and sensitivity. It is also possible to analyse somatic mutations such as those present in samples of cancerous origin. Finally, the degree of methylation of individual CpGs in short DNA sequences can be quantitatively quantified.

Massive sequencing system

High-throughput sequencing equipment that allows obtaining short sequences of up to 300 bp.

Massive sequencing system

High-throughput sequencing equipment that allows obtaining sequences with an average length of more than 30 kb.

Matrx VMS SCIL inhalation anaesthesia. Immunocompromised animal ward

Equipment that allows the induction and maintenance of rodents under anaesthesia for the performance of surgical procedures. Anaesthesia should always be complemented by an adequate analgesia protocol.

Measurement of transmittance of lenses and ocular media. Standard ISO 11979-1:2018

Measurement of spectral transmittance in vitro of lenses and ocular media (cornea, crystalline lens) extracted from patients or animals.

Measurement of visual quality of intraocular lenses. Standard ISO 11979-1:2018

Procedure for the evaluation of the modulation transfer function of intraocular lenses in vitro, from which it is possible to estimate the optical quality of the lens.

Microscope NIKON OPTIPHOT-2, SMZ1

Intravital microscopy system for determination of leukocyte-endothelium interaction in vivo.

Microscopic techniques: optical, confocal and electron scanning

Preparation of dental biological samples.

Microwave Office

High frequency circuit and system design package.

Mini spay dryer Aqueous sol.

Equipment that produces microparticles in dispersion. It is of great interest in the pharmaceutical, food and agricultural industries, since this type of formulation allows to control the release of active ingredients, their stability and functionality through the formation of small solid particles in dispersion. The main objective of the technique is to: reduce volume, facilitate storage and handling, obtain a particle size distribution, have a large specific surface area, change physical or chemical properties and stabilise chemically or biologically.

Miniaturized laser flash photolysis plus nanosecond laser mLFP-111

This transient absorption spectrometer has been developed for spectroscopic and kinetic laser flash photolysis measurements. It includes a ceramic xenon light source; 125 mm monochromator; Tektronix 9-bit digitizer TDS-3000 series with 300 MHz bandwidth; compact photomultiplier and power supply, Pentium computer with 17” monitor and back-up drive, cell holder and fiber optic connectors, fiber optic sensor for laser-sensing pretrigger signal, computer interfaces and the software needed to operate the system. The mLFP-111 instrument does not include the laser, but generates 5 volt trigger pulses suitable for most lasers, including the two-pulse sequence required for YAG lasers (flash lamps and Q-switch), with programmablefrequency and delay. The m-LFP 111 is capable of recording all the transient signals normally acquired with conventional laser flash photolysis (LFP) systems, but in addition it can perform much better in long times time scales. 

Modular system for paraffin embedding and histological sections

Incluye Módulo de incrustación en parafina calentado Leica EG1150, Placa fría para el sistema modular de incrustación de tejidos Leica EG1150 Micrótomo rotatorio semiautomatizado Leica RM2245 y Baño de agua para secciones en parafina Leica HI1210.

Molecular Pathology Laboratory

Molecular Pathology Laboratory: Fluorescent In Situ Hybridisation (FISH), Multiplex Amplified Probe Ligation (MLPA), single nucleotide polymorphism (aSNP) and sequencing (NGS) techniques. Instruments: baths, ovens, Nanodrop, sample homogeniser (FastPrep), thermal cyclers, hybridisation plate (Thernobrite), autoclave and microscopes for immunofluorescence with multiple filters (Axioplan2 Zeiss and Olympus BX-41) with video camera and software for image capture (Metasystem and Cell).

Morphometry Laboratory

Morphometry Laboratory: Morphometric techniques. Instruments: computerised microscopic equipment for Image analysis with the following software: Image Pro-Plus software, AperioImageScope and Panoramic viewer and AngioPath.

Mouse Ventilator

Ventilation equipment for animals weighing between 18 and 70 grams (mouse).

Multi-channel GTEC biosignal amplifiers for ECG, EEG, EOG and biomedical signal acquisition; Multi-channel whole-head EEG acquisition; Wireless biosignal amplifiers for EOG; National Instruments (NI) acquisition cards and signal digitising

Acquisition system and biosignal processing.

Multiparametric rodent monitor

Rodent monitor: for monitoring electrocardiogram, blood pressure, respiratory rate, oxygen saturation.

Multiskan Ascent (Thermo Labsystems)

Absorbance plate reader.

Nanodrop ND1000

Spectrophotometer.

Non-mydriatic retinograph

Retinograph for fundus evaluation in non-dilated pupil conditions with mydriatics.

Ocular aberrometer

Device for in vivo measurement of corneal aberrations.

Oral surgery unit

Equipment of the oral surgery unit on the first floor of the Lluis Alcanyís Foundation Dental Clinic.

PHOTO-REACTOR: Side irradiation model (LZC-5)

UV-Visible exposure tools for controlled irradiation of a wide range of materials.This unit is recommended for customers who only use liquid samples and who therefore prefer side irradiation. The irradiation chamber is approximately 12 inches wide, 12 inches deep and 8.5 inches high. Two switches allow control of the lamps used (8 lamps, 4 each side). An exhaust is needed when using UVC (254 nm) lamps. Fan is included. Different wavelength ranges in the UV and visible regions are available. The irradiation chamber is air-cooled, and the air flow design stabilizes the temperature about 3-4 degrees Celsius above room temperature.

PaceMap (Waalre, The Netherlands) and MatLab (Mathworks Inc., Natick, MA, U.S.A.)

Specific software for the analysis of the recorded signals specially designed for the available mapping systems. In the phase of acquisition of the electrical signals during the experiments, and in the subsequent processing and analysis of the data obtained, two working environments are basically used. On the one hand, the PaceMap software (Waalre, The Netherlands) incorporated in the MapTech acquisition system and, on the other hand, MatLab (Mathworks Inc., Natick, MA, USA) specific programmes for which the necessary codes were developed to extract the information from the records. PaceMap is therefore the software of the cardiac mapping system used in the capture and analysis of electrograms in the experiments and runs under the Windows operating system (Microsoft, Redmond, WA, USA). It performs the acquisition configuration functions, allowing the change of gain, sampling rate and control of the recordings.

Pain assessment tools

FDK 20 algometer, Somedic algometer, Von Frey monofilaments.

Panlab inhalation anaesthesia equipment, small animal operating theatre

Equipment that allows the induction and maintenance of rodents under anaesthesia for the performance of surgical procedures. Anaesthesia should always be complemented by an adequate analgesia protocol.

Peptide synthesizer ABI 433a

Automatic peptide synthesis.

Phase I Clinical Trials Unit

As an integral part of the Onco-Hematology Department, the main objective of the Clinical Trials Unit of the Onco-Hematology Department is to carry out clinical research at all stages of pharmacological development to meet the needs of society and the pharmaceutical industry. The Unit has all the human and material resources necessary to comply with current legislation and regulations applicable to clinical trials, and thus achieve quality clinical research.

Physical and Sports Performance Research Unit

Space equipped with three classrooms and a common area to develop the group's own projects.

Physiotherapy Research Laboratories

Research area with functional and biomechanical assessment material with the possibility of kinematic and ultrasound studies.

Physiotherapy and Exercise Research Laboratory

The laboratory is divided into two areas: an open-plan area for group exercise and another equipped with apparatus and devices for therapeutic exercise.

Psychological assessment through questionnaires in humans

Assessment of mental health and psychological state in humans through questionnaires such as the State-Trait Anxiety Questionnaire (STAI), Perceived Stress Questionnaire (PSS), Resilience Questionnaire (CD-RISK), Beck Depression Questionnaire (BDI-II), etc.

Psychophysical tests for visual function assessment

Proprietary software for measuring chromatic and achromatic contrast sensitivity function, chromatic thresholds, coherence threshold, for monitors and colorimetrically characterised tablets.

Pure fibronectin with mutations in binding sites for integrins, syndins and growth factors

Proteins used for coating materials and analysing cellular response.

Rack Raid Cabinet for virtualisation of IT systems

It is a high-performance mass storage computer system, with a set of redundant disks that allows a 24-hour service to be offered. The technical characteristics of the equipment are as follows:

  • 19-inch rack format.
  • 4 x 10 GbE iSCSI iSCSI host channels / ports with SFP+ connector.
  • 2 SAS expansion ports.
  • Support for RAID 0, 1, 3, 5, 6, 10, 30, 50, 60.
  • Redundant controller and hot swap.
  • 2 GB cache memory per controller.
  • Hot swap cache battery per controller.
  • Dynamic capacity expansion.
  • LUN Mapping.
  • Possibility of hot spare and hot swap disks.
  • Redundant power supply and fan modules.
  • Backplane for 16 SAS 6 Gbit disks.
  • 16 Hitachi 600 Gbytes 15,000 rpm 6 Gbit SAS disks.
  • Capacity to support up to 112 SAS 6 Gbit disks.
  • SES/SMART.
  • Management via LCD with keypad, telnet over Ethernet and web browser with GUI.
  • Remote alarm notification.
Rat and rabbit Ventilator

Ventilation equipment for animals weighing between 250 and 10 kg.

Reality room

Cylindrical immersive visualisation system with 3D stereoscopic projection and capacity for 40 people.

Rodent blood pressure equipment

A device designed to measure non-invasive tail blood pressure in rats and mice in up to 4 animals simultaneously.

SAVANT DNA 120 SpeedVac Concentrator

DNA concentrator.

SORVALL RC5C PLUS (SORVALL)

Sorvall centrifuge with SLA3000 SuperLIte® and SS34 rotors.

Scientific calculation cluster

Computer cluster for scientific calculation and data storage.

Server calculator

Server Calculator MacOS 4 Core Intel Xeon 2.8GHz 16GB RAM SSD 128GB, 1TB HDD.
 

Shack–Hartmann wavefront sensor

Measurement of optical aberrations of ophthalmic lenses.

Smiling faces programme

Perceptual training programme to improve the visual function of amblyopic people.

Solid phase extraction (SPE) systems

Equipment for semi-automatic solid phase extraction. It allows simultaneous extraction and elution of 12 extraction cartridges using a conventional vacuum.

Sotax flow-through dissolution system

This is a flow-through dissolution equipment. It is a flow-through dissolution method (undefined volume of medium) and the sample is placed in a small cell through which the medium is circulated at 37 °C and at a predetermined flow rate. This flow-through system is a dissolution test used by the pharmaceutical industry to characterise the dissolution properties, active drug release and dissolution of a dosage formulation. The dissolution test is used to formulate the dosage form of drugs and to develop quality control specifications for their manufacturing process.

Stage 2, 3rd floor, Faculty of Psychology, with three workspaces

Server with METBA System (remote monitoring and evaluation system) and Tests (online test presentation system) and video recording system.

Statistical analysis

The UV Statistics Unit works with experts in the use of computer equipment and specific software. The main software used for data analysis is the free R Software.

Structural characterisation of proteins using spectroscopic techniques

UV-visible absorbance spectroscopy, circular dichroism and fluorescence.

Structured light

Projector equipment, video camera, interactive touch-screen and specific image analysis software.

System for the evaluation of roadside equipment and image processing systems

A steel gantry with a span of 18 m and a gauge of 550 m, located on the CV 35 road, is available for the evaluation of traffic monitoring systems in real conditions of luminosity and traffic. The gantry consists of 3 mobile CCTV cameras of different quality, an infrared spotlight, an electronic toll sensor and a magnetic sensor located under the gantry. The information from the systems is sent to an ERU and from there to the laboratory from where images are received in real time and the installed equipment can be controlled.

Tanita scale

Bioimpedance scale.

Technological support laboratory (BIO-ITACA Institute of the Universitat Politècnica de València)

Technological support laboratory belonging to the BIO-ITACA Institute of the Universitat Politècnica de València (UPV). Polytechnic City of Innovation- CPI-(Building 8G). Vera Campus. It has the necessary material for research and development of new biomedical equipment and tools applied to cardiac electrophysiology.

Tendinopathy assessment

Dynamic test for the assessment of tendon injuries by means of specific exercises.

Texas Instruments (TI) DSP-based digital signal processing systems

Digital signal processors.

Thermal imaging camera

Thermal imaging camera FLIR E60bx (FLIR Systems, Wilsonville, OR).

Thermal imaging cameras

Scientific and demonstration thermographic cameras. Specific image analysis software.

Time-domain analysis of ventricular fibrillation

Activation times at each electrode are determined by identifying the moments of maximum negative slope of the ventricular electrograms. If the electrograms show two or more deflections, then the steepest slope of the activation complex is assigned as the local activation time. The mean of the consecutive activation intervals during ventricular fibrillation and the 5th percentile of the histogram of intervals between successive activations is determined for each channel of the multielectrode. We use the 5th percentile (shortest VV intervals) as an approximation of the functional refractory period during ventricular fibrillation.

UV/VIS HP 8453

The Agilent 8453 spectrophotometer is the core of powerful and productive systems for routine and occasional users that are easy to use and integrate seamlessly into the modern laboratory. The spectrophotometer comes equipped with all the diode-array advantages – fast scanning, excellent sensitivity, virtually absolute wavelength reproducibility, exceptional ruggedness and reliability, minimum maintenance and open sample area, and significant improvements in optical performance. Better than two nanometer resolution, wavelength range of 190 to 1100 nm and less than 0.03 % stray light is standard. 

Ultra-high resolution liquid chromatograph - High resolution mass spectrometer

It is an equipment focused on the identification of unknown polar compounds. The high resolution mass spectrometer (orbitrap) allows us to identify the most likely molecular formula and then identify the structure.

Ultrasonic Densitometer

Ultrasonic Densitometer Sonost 3000 (OsteoSys Co., Ltd. Seoul, Republic of Korea).

Ultrasound machines

Edan U50 ultrasound machine with 10-15 Mhz probe (Edan Instrument Inc., Nanshan Shenzhen, China), logicC5 ultrasound machine (General Electric), SAMSUNG HS30 (SAMSUNG MEDISON CO., LTD).

Uv-vis spectrophotometer

The spectrophotometer is a device for comparing the radiation absorbed or transmitted by a solution that contains an unknown amount of solute and one that contains a known amount of the same substance.

Virtual reality equipment

In the Faculty of Psychology, teaching laboratories unit (Stage 3), we have complete equipment for the dispensing of treatments (EPR) using virtual reality (44' TV, kinect devices, adapted computer, etc.).

Vision Laboratory

Laboratory of Psychophysics of Vision and Visual Perception, located in the Faculty of Physics and attached to the Department of Optics and Optometry and Vision Sciences.

X-RAD 225XL/OptiMAX irradiator

This system can be used to irradiate models in vivo (rats and mice) and in vitro (cell cultures). In addition, the integrated imaging system (OptiMAX) can provide bioluminescence imaging, 2D X-ray imaging and radioisotope imaging.