Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput Bioanalysis

Description

Quality and methodology applied to laboratories of routine (ISO 17205 Standard) and research: Development of ad hoc metrological tools, technical protocols, acceptance criteria, validation, quality assurance, control charts, uncertainty, including supporting software. Design of experiments, optimisation, simulation of future results. Research and development of high-throughput (bio)analysis methods (Liquid chromatography, Capillary electrophoresis, Mass spectrometry) for the separation and determination of molecules (including chiral) with analytical and bioanalytical applications. (Bio)sensors. Chemical assays of relevant compounds in environmental samples (water, sludge, soil, etc.).

Added value: In vitro estimation of ecotoxicological parameters. Chemical assays of bioactive molecules (in urine, plasma, saliva, etc.). Added value In vitro estimation of ADME/TOX indicators. Development of molecular biointeraction models. Computational simulation methods (“in silico” via “Molecular Docking”). Pharmacophores. QSAR.

Goals CT

Quality and metrology applied to laboratories.
Development of metrological tools for companies and laboratories.
Research and development of high-throughput (bio)analysis methods.
Chemical assays of relevant compounds in environmental samples and bioactive molecules.

Research lines

Analysis of bioactive molecules
Chemical assays of bioactive molecules (in urine, plasma, saliva, etc.). Added value In vitro estimation of ADME/TOX indicators.
Molecular and computational biointeraction
Development of molecular biointeraction models. Computational simulation methods (“in silico” via “Molecular Docking”). Pharmacophores. QSAR.
Quality and Metrology in Laboratories
ISO 17205 Standard. Development of ad hoc metrological tools, technical protocols, acceptance criteria, validation, quality assurance, control charts, uncertainty, including supporting software. Design of experiments, optimisation, simulation of future results.
R&D in (bio)analytical methods
Research and development of high-throughput (bio)analysis methods (Liquid chromatography, Capillary electrophoresis, Mass spectrometry) for the separation and determination of molecules (including chiral) with analytical and bioanalytical applications. (Bio)sensors.
Analysis of environmental samples
Chemical assays of relevant compounds in environmental samples (water, sludge, soil, etc.). Added value: In vitro estimation of ecotoxicological parameters.

Management

MEDINA HERNANDEZ, MARIA JOSE
PDI-Catedratic/a d'Universitat

View details

Members

ESCUDER GILABERT, LAURA
PDI-Titular d'Universitat

View details

MARTIN BIOSCA, YOLANDA
PDI-Titular d'Universitat

View details

SAGRADO VIVES, SALVADOR
PDI-Catedratic/a d'Universitat

View details

Scientific production by UV researcher

SAGRADO VIVES, SALVADOR
PDI-Catedratic/a d'Universitat
ContraerExpandir
- Martí-Andrés, P.; Escuder-Gilabert, L.; Martín-Biosca, Y.; Sagrado, S.; Medina-Hernández, M.J.(2015)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chemical Education, 92, pp. 903 - 906. ISSN: 0021-9584
- Asensi-Bernardi, L.; Martín-Biosca, Y.; Escuder-Gilabert, L.; Sagrado, S.; Medina-Hernández, M.J.(2015)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisBiomedical Chromatography, 29(11), pp. 1637 - 1642. ISSN: 0269-3879
- Ezquer-Garin, C.; Escuder-Gilabert, L.; Martín-Biosca, Y.; Ferriols-Lisart, R.; Sagrado, S.; Medina-Hernández, M.J.(2016)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisTalanta, 150, pp. 510 - 515. ISSN: 0039-9140
- Escuder-Gilabert, L.; Martín-Biosca, Y.; Medina-Hernández, M.J.; Sagrado, S.(2016)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chromatography A, 1467, pp. 391 - 399. ISSN: 0021-9673
- Escuder-Gilabert, L.; Martín-Biosca, Y.; Pérez-Baeza, M.; Sagrado, S.; Medina-Hernández, M.J.(2018)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisWater Research, 141, pp. 57 - 64. ISSN: 0043-1354
- Escuder-Gilabert, L.; Martín-Biosca, Y.; Pérez-Baeza, M.; Sagrado, S.; Medina-Hernández, M.J.(2018)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chromatography A, 1568, pp. 140 - 148. ISSN: 0021-9673
- Martín-Biosca, Y.; Escuder-Gilabert, L.; Medina-Hernández, M.J.; Sagrado, S.(2018)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chromatography A, 1567, pp. 111 - 118. ISSN: 0021-9673
- Martín-Biosca, Y.; Escuder-Gilabert, L.; Pérez-Baeza, M.; Sagrado, S.; Medina-Hernández, M.J.(2019)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisInternational journal of advanced research in chemical sciences, 6(1), pp. 16 - 23. ISSN: 2349-039X
- Escuder-Gilabert, L.; Martín-Biosca, Y.; Sagrado, S.; Medina-Hernández, M.J.(2019)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisEnvironmental Pollution, 252, pp. 128 - 136. ISSN: 0269-7491
- Escuder-Gilabert, L.; Martín-Biosca, Y.; Sagrado, S.; Medina-Hernández, M.J.(2019)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisEnvironmental Pollution, 255, p. 113275. ISSN: 0269-7491
- Martín-Biosca, Y.; Escuder-Gilabert, L.; Pérez-Baeza, M.; Sagrado, S.; Medina-Hernández, M.J.(2020)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisEnvironmental Chemistry, 17(3), pp. 278 - 288. ISSN: 1448-2517
- Pérez-Baeza, M.; Escuder-Gilabert, L.; Martín-Biosca, Y.; Sagrado, S.; Medina-Hernández, M.J.(2020)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chromatography A, 1625, p. 461334. ISSN: 0021-9673
- Pérez-Baeza, M.; Escuder-Gilabert, L.; Martín-Biosca, Y.; Sagrado, S.; Medina-Hernández, M.J.(2020)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chromatography A, 1625, p. 461281. ISSN: 0021-9673
- Gumede, N.J.; Nxumalo, W.; Bisetty, K.; Escuder Gilabert, L.; Medina-Hernandez, M.J.; Sagrado, S.(2020)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisBioorganic Chemistry, 94, 103462. ISSN: 0045-2068
- Y. Martín‐Biosca; L. Escuder‐Gilabert; S. Sagrado; M.J. Medina‐Hernández(2021)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisSeparations, 8(2). ISSN: 2297-8739
- Pérez-Baeza, M.; Escuder-Gilabert, L.; Martín-Biosca, Y.; Sagrado, S.; Medina-Hernández, M.J(2022)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chromatography A, 1680 (463430). ISSN: 0021-9673
- Pérez-Baeza, M.; Escuder-Gilabert, L.; Martín-Biosca, Y.; Sagrado, S.; Medina-Hernández, M.J.(2022)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chromatography A, 1673(463073). ISSN: 0021-9673
- Pérez-Baeza, M.; Martín-Biosca, Y.; Escuder-Gilabert, L.; Medina-Hernández, M.J; Sagrado, S(2022)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisJournal of Chromatography A, 1672(463048). ISSN: 0021-9673
- Gloria Ebube Uwaya; Salvador Sagrado; Krishna Bisetty(2022)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisTalanta Open, 6(100144), pp. 1 - 13. ISSN: 2666-8319
- Matshidiso Lephalala; Salvador Sagrado Vives; Krishna Bisetty(2024)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisScience of the Total Environment, 942(173754), pp. 1 - 11. ISSN: 0048-9697
- Sagrado, S; Pardo-Cortina, C; Escuder-Gilabert, L; Medina-Hernández, M.J.; Martín-Biosca, Y(2024)Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput BioanalysisAnalytical Chemistry, 96, pp. 12205 - 12212. ISSN: 0003-2700
- Escuder-Gilabert, L.; Martín-Biosca, Y.; Sagrado, S.; Medina-Hernández, M.J.,(2017).Enantioselective drug-plasma protein binding studies by capillary electrophoresis.Capillary Electrophoresis: Trends and Developments in Pharmaceutical Research.. (pp. 225 - 257)..
- Martín-Biosca, Y.; Escuder-Gilabert, L.; Sagrado, S.; Medina-Hernández, M.J.,(2017).Electrophoretically mediated microanalysis for evaluation of enantioselective drug metabolism.Capillary Electrophoresis: Trends and Developments in Pharmaceutical Research.. (pp. 277 - 303)..
- Salvador Sagrado; Emilio Bonet; Mª José Medina; Yolanda Martín; Laura Escuder,(2017).Manual práctico de calidad en los laboratorios. Enfoque ISO 17025... (pp. 1 - 408)..
- Editores: Suvardhan Kanchi; Salvador Sagrado; Myalowenkosi Sabela; Krishna Bisetty,(2017).Capillary Electrophoresis Trends and Developments in Pharmaceutical Research... (pp. 1 - 395)..

CNAE

Associated structure

Analytical Chemistry

www.uv.es/quimana

dep.quimica.analitica@uv.es

Contact group details

Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput Bioanalysis (GAMM-CyBAR)

Burjassot/Paterna Campus

C/ Dr. Moliner, 50

46100 Burjassot (Valencia)

Contact people

MEDINA HERNANDEZ, MARIA JOSE
PDI-Catedratic/a d'Universitat

View details

Research Group on Multivariate and Multicomponent Analysis - Quality and High-throughput Bioanalysis - GAMM-CyBAR