Description
The addition of additives to the mobile phase allows the volume of organic solvent to be reduced in conventional reversed-phase HPLC. When the additive is biodegradable, a clean method (classified as Green Chemistry) is achieved. In particular, by using microemulsions, water and soap separations are developed.
Keywords
HPLC, green chemistry, biodegradable surfactants, pharmaceutical analysis
Frascati classification
