• Universitat de València
• University of Castilla La Mancha
• Servicio Andaluz de Salud
• Fundación INCLIVA

• María Gloria Bueno García
• Óscar Déniz Suárez
• María del Milagro Fernández Carrobles
• Marcial García Rojo
• Irene Tadeo Cervera

It is now widely accepted that tumour growth and metastasis depend on angiogenesis and that the lymphatic system, hitherto thought to play a passive role in cancer metastasis, is now known to play an integral role in the metastatic spread of disease.

Researchers from the Universitat de València together with the University of Castilla La Mancha, the Servicio Andaluz de Salud and the Fundación INCLIVA have developed ANGIOPATH, a morphometric tool capable of easily segmenting blood and lymphatic vessels to study vascularisation. ANGIOPATH is able to segment closed and open vessels and obtain information on the density, size and shape of the total vasculature and the vasculature of all vessel segments, according to their size.

The main customers would be researchers in the field of vascularisation, including the fields of cancer, inflammatory diseases, cardiovascular diseases or dermatological pathologies.

Unlike other imaging tools, ANGIOPATH:

• Provides vessel closure when the entire vessel perimeter is not completely stained.
• It provides information on the different vessel segments and not only on the total vascularisation of the sample.
• Uses automatic algorithms, which do not require manual interaction, but allow manual correction.
• Can process large image files.

• Registered intellectual property