Women present a specific profile in many areas of ageing, including frailty, chronic diseases (examples are clearly musculoskeletal diseases, cardiovascular diseases, certain forms of cancer, cognitive impairment or depression), social interaction, and quality of life.
Our activity has focused on the female determinants of osteoporosis and cardiovascular diseases, quality of life after menopause, cognitive impairment and, more recently, frailty. More recently, we have also been doing research on endometriosis, a disease that causes morbidity and affects quality of life, and whose impact on healthy ageing is just beginning to be understood.
We have carried out basic and applied research work, and are therefore an example of a multidisciplinary group with interaction between basic and clinical researchers and with a profile of publications and funded projects that meet this criterion.
- Health ageing in women.
- Osteoporosis.
- Reproductive senescence.
- Endometriosis.
- Frailty and cognitive impairment.
- Frailty in women
Frailty is a state of vulnerability to illness and death and in its early stages can be prevented. It is more prevalent in women than in men in every age group. Multidimensional frailty, both physically and cognitively, its prevalence and characteristics are investigated.
- Psico-social frailty
The psychological aspect of frailty includes clinical (cognitive and emotional), functional and socio-familial aspects as well as different demographic and lifestyle variables. The aim is to research and define the profile of these variables in different population groups.
- Prevention of chronic disease in women
Women have a specific disease profile, which is particularly evident in some pathologies, such as osteoporosis, heart disease, etc. It is important to develop prevention policies, especially through healthy lifestyles, including physical activity, and with the support of ICTs.
- Long-term effects on maternal and oocyte ageing on offspring; Assisted Reproduction and Infertility; Physiology and Endocrinology
The objectives of these lines of research are to clarify at epidemiological/population, cellular and molecular/epigenetic levels the effect of maternal oocyte ageing and assisted reproduction techniques on the reproductive health of women and their offspring.
- Genetics of osteoporosis and bone fractures
The objectives of this line of research are, on the one hand, to identify genes and polymorphisms associated with bone phenotypes through candidate gene association studies and through translational studies from animal models, and on the other hand, the functional characterisation of each variant.
Contributor/s
- Pedro Belo Santos - Instituto Politécnico de Coimbra (Portugal)
- Sara Cholvi Camarasa - Clinical University Hospital of Valencia
- Ana Cristina Fulgencio Cruz - Fundação ADFP - Assistência, Desenvolvimento e Formação Profissional (Portugal)
- Raul Gómez Gallego - Foundation for Research at the Clinical University Hospital of the Comunitat Valenciana
- Carmela Llinares Valldecabres - Clinical University Hospital of Valencia
- Isabel Moscardó Chafer - Clinical University Hospital of Valencia
- Fernando Luis Nunes Rodrigues - Instituto Politécnico de Leiría (Portugal)
- Carlos Pascual Botia - Clinical University Hospital of Valencia
- Francisco de Jesus Vazquez Martinez - Ministry of Economy, Planning and Development of the Government of the Dominican Republic (Madrid)
Blasco Ibáñez Campus
Av. Blasco Ibáñez, 15
46010 València (Valencia)
