Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and Cosmetics

Description

The characterisation of drug release, absorption, distribution, metabolism and excretion processes has a major impact on medicine design and provides rational criteria for selecting the most appropriate dosage form, route and method of administration. These aspects are particularly important for drugs with bioavailability problems and/or high pharmacokinetic variability.

The research group is dedicated to pre-formulation studies of medicine (and cosmetics), characterisation of drug release and/or absorption processes from the medicine containing them and evaluation of the pharmacokinetic profile after its administration to the organism.

Goals CT

Provide knowledge to facilitate the development of effective and safe dosage forms and to enable the selection of dosing regimens

Research lines

Pharmacokinetic evaluation of drugs administered intravenously, orally and through the skin
Pharmacokinetic evaluation of drugs administered intravenously, orally and through the skin, especially those with bioavailability problems and/or plasma concentrations with high variability and which correlate poorly with the dose administered.
Preformulation
Galenic development, preferably modified-release oral and topical dosage forms. Evaluation of transdermal administration with iontophoresis. The studies help to guide the selection of the adjuvant substances used in the formulation of…

Management

MERINO SANJUAN, MATILDE
PDI-Catedratic/a d'Universitat
Coordinador/a de Programa de Doctorat

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Members

DIEZ SALES, OCTAVIO
PDI-Emerit/a Universitat

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MANGAS SANJUAN, VICTOR
Alumn.-Servei de Formacio Permanent

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MERINO SANJUAN, VIRGINIA
PDI-Catedratic/a d'Universitat
Secretari/a de Departament
Responsables de Gestio Academica
Coordinador/a Titulacio de Grau

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NACHER ALONSO, AMPARO
PDI-Titular d'Universitat

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Scientific production by UV researcher

MERINO SANJUAN, VIRGINIA
PDI-Catedratic/a d'UniversitatSecretari/a de DepartamentResponsables de Gestio AcademicaCoordinador/a Titulacio de Grau
ContraerExpandir
- García-Arieta A, Gordon J, Gwaza L, Merino V, Mangas-Sanjuan V.(2023)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsPharmaceutics, 15, p. 601. ISSN: 1999-4923
- Villanueva-Martínez A, Merino V, Ganem-Rondero A.(2022)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsJournal Of Drug Delivery Science And Technology, 69, p. 103111. ISSN: 1773-2247
- Cámara-Martinez I, Blechar JA, Ruiz-Picazo A, Garcia-Arieta A, Calandria C, Merino-Sanjuan V, Langguth P, Gonzalez-Alvarez M, Bermejo M, Al-Gousous J, Gonzalez-Alvarez I.(2022)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsInternational Journal of Pharmaceutics, 614, p. 121415. ISSN: 0378-5173
- Gigante V, Pauletti GM, Kopp S, Xu M, Gonzalez-Alvarez I, Merino V, McIntosh MP, Wessels A, Lee BJ, Rezende KR, Scriba GKE, Jadaun GPS, Bermejo M.(2021)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsADMET & DMPK, 9(1), pp. 23 - 39. ISSN: 1848-7718
- López-Sánchez L; Miralles P; Salvador A; Merino-Sanjuán M; Merino V.(2021)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsRegulatory Toxicology and Pharmacology, 122, p. 104881. ISSN: 0273-2300
- Singhal M, Serna C, Merino V, Kalia YN.(2021)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsEuropean Journal of Pharmaceutics and Biopharmaceutics, 166, pp. 175 - 181. ISSN: 0939-6411
- Alambiaga-Caravaca AM, Domenech-Monsell IM, Sebastián-Morelló M, Calatayud-Pascual MA, Merino V, Rodilla V, López-Castellano A.(2021)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsInternational Journal of Pharmaceutics, 606, p. 120921. ISSN: 0378-5173
- Bueno-López C, Tamarit-Martínez C, Alambiaga-Caravaca AM, Balaguer-Fernández C, Merino V, López-Castellano A, Rodilla V.(2021)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsPharmaceutics, 14, p. 1240. ISSN: 1999-4923
- Ocaña J, Monleón-Getino T, Merino V, Peris D, Soler L.(2020)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsPharmaceutics, 12, p. 318. ISSN: 1999-4923
- Figueroa-Campos A, Sánchez-Dengra B, Merino V, Dahan A, González-Álvarez I, García-Arieta A, González-Álvarez M, Bermejo M.(2020)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsPharmaceutics, 12(12), p. 633. ISSN: 1999-4923
- Teruel AH, González-Álvarez I, Bermejo M, Merino V, Marcos MD, Sancenón F, González-Álvarez M, Martínez-Máñez R.(2020)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsInternational Journal Of Molecular Sciences, 21(18), p. 6502. ISSN: 1661-6596
- Zhengguo Xu; Víctor Mangas-Sanjuán; Matilde Merino-Sanjuán; Virginia Merino; Alfredo García-Arieta(2020)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsPharmaceutics, 12(12), p. 1159. ISSN: 1999-4923
- Martínez-Martínez M, Rodríguez-Berna G, Bermejo M, Gonzalez-Alvarez I, Gonzalez-Alvarez M, Merino V.(2019)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsEuropean Journal of Pharmaceutics and Biopharmaceutics, 136, pp. 174 - 183. ISSN: 0939-6411
- Daniel Ferri; Ana M. Costero; Pablo Gaviña; Margarita Parra; Virginia Merino; Adrián H. Teruel; Félix Sancenón; Ramón Mártínez-Máñez(2019)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsInternational Journal of Pharmaceutics, 561, pp. 93 - 101. ISSN: 0378-5173
- Martínez-Moreno J; Mir-Palomo S; Merino V; Nácher A; Merino-Sanjuán M(2019)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsColloids and Surfaces B-Biointerfaces, 118, pp. 1 - 5. ISSN: 0927-7765
- Adrián H. Teruel; Édgar Pérez-Esteve; Isabel González-Álvarez; Marta González-Álvarez; Ana M. Costero; Daniel Ferri; Pablo Gaviña; Virginia Merino; Ramón Martínez-Máñez; Félix Sancenón(2019)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsMolecular Pharmaceutics, 16, pp. 2418 - 2429. ISSN: 1543-8384
- Singhal M, Merino V, Rosini M, Cavalli A, Kalia YN.(2019)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsMolecular Pharmaceutics, 16(8), pp. 3460 - 3468. ISSN: 1543-8384
- Mangas-Sanjuán V; Pleguezuelos-Villa M; Merino-Sanjuán M; Hernández MJ; Nácher A; García-Arieta A; Peris D; Hidalgo I; Soler L; Sallan M; Merino V.(2019)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsPharmaceutics, 11(10), pp. 503 - 515. ISSN: 1999-4923
- Pleguezuelos-Villa M; Merino-Sanjuán M; Hernández MJ; Nácher A; Peris D; Hidalgo I; Soler L; Sallan M; Merino V.(2019)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsInternational Journal of Pharmaceutics, 572(118755). ISSN: 0378-5173
- Gonzalez-Alvarez I, Ruiz-Picazo A, Selles-Talavera R, Figueroa-Campos A, Merino V, Bermejo M, Gonzalez-Alvarez M.(2024)Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and CosmeticsPharmaceutics, 16, p. 390. ISSN: 1999-4923
- Jesús Blesa Jarque; Mª Amparo Blázquez Ferrer; Antonio Cilla Tatay; María José Esteve Mas; Carmel Ferragud Domingo; Mª Luisa Ferrándiz Manglano; Teresa Mª Garrigues Pelufo; Rosa Mª Giner Pons; Mª Carmen González-Mas; Mª Luisa Guillem Domínguez; Mª Dolores Ivorra Insa; Virginia Merino Sanjuan; Mª Carmen Recio Iglesias; Carla Soler Quiles,(2020).Proyecto ApS multidisciplinar de la facultat de farmàcia de la universitat de València.El papel del Aprendizaje-Servicio en la construcción de una ciudadanía global.. (pp. 563 - 566)..

CNAE

Manufacture of basic pharmaceutical products

Associated structure

Inter-university Research Institute for Molecular Recognition and Technological Development (IDM)

www.uv.es/idm

idm@uv.es

Contact group details

Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and Cosmetics (EVALUAMECO)

Burjassot/Paterna Campus

Av.Vicent Andrés Estellés, s/n

46100 Burjassot (Valencia)

Contact people

MERINO SANJUAN, MATILDE
PDI-Catedratic/a d'Universitat
Coordinador/a de Programa de Doctorat

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Research Group on Formulation, Technologycal Assessment and Pharmacokinetic Evaluation of Drugs and Cosmetics - EVALUAMECO