Research Group on Study on Stability, Bioavailability and Biological Effects of Components of the Food and Nutritional Evaluation - BIONUTEST
The BIONUTEST group specialises in the study of components of food ingredients and food, including nutrients, as well as other bioactive components (carotenoids, sterols, sialic acids, gangliosides and polyphenols).
- Quantification and stability studies of: components of the lipid fraction of food and ingredients; Maillard reaction compounds; nitrogen fraction: (proteins, casein phosphopeptides and amino-acids); minerals of nutritional interest; antioxidants and assessment of antioxidant capacity.
- Bioavailability assessment: a) in vitro by application of gastrointestinal simulation and uptake and transport models in combined systems incorporating cell cultures (Caco-2, HepG2); b) in vivo by determination of food components and metabolites in biological fluids and faeces, from clinical trials and animal experimentation.
- Assessment of biological effects by in vitro techniques: cytoprotection and/or cytotoxicity, markers of oxidative stress, inflammation and apoptosis, using cell cultures.
- Advice and assessment of: a) Nutritional and functional quality of formulations, food, ingredients, diets and/or menus and b) Food information: mandatory and nutritional labelling, nutrition and health claims.