ADME-tox prediction of drugs using Molecular Topology.
Ecotoxicity bioassays. Toxic accumulation in living organisms. Toxicity in environmental matrices. Biomarkers of oxidative stress and xenobiotic exposure.
Assessment of biological effects of components of food and food ingredients: cytoprotection and/or cytotoxicity, markers of oxidative stress, inflammation and apoptosis, using cell cultures.
It consists in the development of products based on bioactive ingredients of natural origin or of botanical or microbial origin with possible bio-stimulant / biocontrol effect in the field and to reduce the growth of toxin-producing fungi in fourth range fruit, cereals, dairy products, cured meat, nuts, etc.
Study of the presence, transport, fate and bioavailability of emerging and priority pollutants in environmental compartments. Environmental risk assessment. Development of methods for environmental forensics and sewage epidemiology.
Advanced chemical analysis. Characterisation of food quality and safety within the framework of food legislation. Foodomics: profiling and fingerprinting techniques for food characterisation, authenticity and origin characterisation.
Fundamental and applied limnology: Dynamics and functioning of epicontinental aquatic ecosystems. Community structure and functional diversity. Assessment of environmental and conservation status. Microbial ecology in lentic ecosystems: Study of the composition and functionality of the microbial community by molecular techniques. Metagenomics. Metabarcoding and e-DNA Biogeochemistry and carbon balances in Mediterranean wetlands, fluxes of carbonate greenhouse gases. Effects of environmental properties and conservation status on the climate change mitigation capacity of lentic ecosystems. Ecotoxicology. Geographic information systems (GIS). Remote-sensing. Polar limnology.
Advanced analysis. Human diet studies. Integrated risk assessment.
Study of medicinal plants, the structure of plant organs and the substances that provide medicinal, toxic or bromatological proprieties. This study is oriented towards the rational use of resources and its results can be directly applied to health, industry and agriculture.
Development of fast, accurate and selective analysis methods for the determination of mycotoxins in food to assess population intake.
This group is composed of professors from the Departments of Microbiology and Ecology and Analytical Chemistry of the Universitat de València. Its research activity is of a multidisciplinary nature and has been developed in applied areas in the fields of health, science and quality control.
Determine the toxicity of mycotoxins by in vivo methods, using different species of rodents, and alternative methods in vitro on mammalian cell lines (from ovary, kidney, liver, intestine, etc.)
Basic translational research on biochemical and molecular mechanisms related to free radical formation and oxidative stress in metabolic, cardiovascular and tumour diseases. Molecular signalling pathways in DNA damage and repair.
