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Advanced human liver cell models

Description

In this line, the main objective is to develop and improve human liver cell models in vitro so that they maintain a differentiated adult phenotype and show a pathophysiological response similar to that observed in vivo.

Keywords

hepatocytes, continuous liver lines, cell cultures, 2D cultures, 3D cultures, biomaterials, spheroids, organoids, differentiated hepatic phenotype, cellular response to drugs, inter-individual variability, idiosyncrasies

Frascati classification