University of Valencia logo Logo Scientific Technological Offer Logo del portal

Mitochondrial-endothelial dysfunction, reticulum stress and autophagy in type 2 diabetes: pathophysiological and therapeutic implications

Description

We studied type 2 diabetes and mitochondrial dysfunction, having shown that it correlates with the development of silent ischaemic heart disease. We have also shown that high levels of myeloperoxidase correlate with the development of diabetic nephropathy in type 2 diabetes.

Keywords

type 2 diabetes, mitochondria, endothelium, cardiometabolic disease, humans

Frascati classification