RD06/0010/1006 (Simón Vallés, Carlos Antonio, Group
PI) 2007-2013
Cell Teraphy Network.
Spanish Ministry of Health.
Tercel is a cross network dedicated to research in cell therapy. More
than 160 researchers from Spain, in 27 research groups and 6
associated clinical groups, are active (with international partners)
in order to transfer to National Health System advances and
discoveries generated in this new therapeutic technique. The Red Cell
Therapy (Tercel) is divided into 6 platforms, providing techniques
and equipment to all research groups, and in 3 general areas of
research for the 3 germ layers (endoderm, mesoderm, and ectoderm).
PROMETEO/2008/163 (Simón Vallés, Carlos Antonio,
PI)
2008-2011
Conselleria d’Educació, Generalitat Valenciana.
Isolation and characterization of endometrial somatic stem cells in
endometriosis. Pathogenic and therapeutic implications.
This project aims the identification and characterization of somatic
stem cell population of endometrium in endometriosis using cell
biology techniques previously described and published by our group in
a mouse model, and even unprecedented in human and we developed in
our previous project SAF 2004-00204 which was aimed at identifying
somatic stem cell population in healthy women. Finally the somatic
stem cell population "endometriotic" identified in this project will
be used to search for therapeutic targets that inhibit clonal growth
as a new therapeutic approach to treat endometriosis.
LOGO CE
PROMETEOII/2013/018 (Simón Vallés, Carlos Antonio,
PI)
2013-2016
Conselleria d’Educació, Generalitat Valenciana.
Isolation and characterization of endometrial somatic stem cells in
endometriosis. Pathogenic and therapeutic implications.
Identification of Endometrial Stem Cell Markers. From Animal Models
to Human Endometrial Stem Cell Therapy
Our hypothesis is based on the analysis of specific Endometrial Stem
Cell Markers in order to identify SSC in human endometrium and to
know more about the localization, regulation and cellular niche in
human endometrium. We pretend to localize specific Stem Cell Markers
in the endometrial cells in different menstrual phases. Moreover, we
aim to isolate and to differentiate in vitro and in vivo human
endometrium from those endometrial markers cells. Finally we prove
our results in two established animal models.
LOGO CE