The results of the basic research carried out by the group are always analysed from multiple angles with the aim of seeking their clinical application. Within this more translational facet of our research, our main objectives are to develop new diagnostic, monitoring and clinical prognostic procedures for drug-induced liver injury. This research involves setting up several clinical trials to validate the proposed procedures. Another priority objective is to obtain induced stem cells from patients with various liver diseases for their correction and subsequent use in cell therapy. In this same context, the group has also pioneered human hepatocyte transplants as an alternative to orthotopic organ transplantation.
Drug-induced liver injury, biomarkers, clinical diagnosis and follow-up, hepatocyte transplantation, induced stem cells, gene therapy, cell therapy