In this line of research, new non-invasive microscopy techniques with high optical sectioning are developed, such as confocal microscopy, structured illumination microscopy (SIM) or digital holographic microscopy (DHM).
Development in the implementation of 3D image capture techniques based on taking multiple images with different perspectives. This multi-perspective information allows both the reconstruction of the original 3D scene and the development of new 3D digital processing techniques.
Using Monte Carlo simulations and the ACE system, to which the group has access thanks to the Elekta-La Fe-UV collaboration, we will proceed to locate systems where the formalism currently used in high-rate brachytherapy treatment planning is no longer valid.
Systems for the collection, processing and statistical treatment of data. Advanced database management applications. DWH design and implementation. Re-engineering of systems and client/server architectures. Data modelling. Document management. Multimodal systems. Hospital management.
Obtaining new specific parameters for the diagnosis of pathologies by processing biosignal recordings in humans and test animals. Risk prediction of sudden death (malignant arrhythmias or heart attacks). Support systems for neurosurgery through the analysis, prediction and detection of pathologies by means of intracerebral MER and cortical EEG recordings.
We want to find out what are the implications of removing the RGD sequence located in the 10th repeat of type III: 1) can a5ß1 integrins and av class bind to other regions of the FN or are they totally dependent on this sequence? can FN fibrillogenesis occur in the absence of this?
Validation of clinically useful tests.
Detection of genomic changes. Identification and characterisation of unusual cases.
Histological category determination and neuroblastic differentiation. Expression studies.
To assess the postural control of different populations as well as its evolution during childhood and adolescence.
Ventricular stretch, a pathophysiological condition present in situations involving pressure or volume overload of the cardiac chambers, generates proarrhythmogenic electrophysiological alterations. Search for and identification of pharmacological agents that counteract these effects.
Study of the protective electrophysiological effects of chronic physical exercise: influence of the autonomic nervous system and mitochondrial oxidative stress. Analysis of the effects on electrophysiological changes induced by myocardial ischaemia in relation to IKATP current.
Research by prioritising the use of corpus tools from a variety of genres and discourses in order to evaluate the effectiveness of corpus tools.
Evaluation of different factors of prevention and treatment of cognitive impairment and mental health related to the role of new technologies.
The study of musculoskeletal injuries via functional assessment with the use of ultrasound scanning and biomechanical material for the improvement of overall function and performance and the prevention of injuries.
Assessment of the body composition, the nutritional status and the effectiveness of substances that increase sports performance. Assessment and development of products aimed at ergogenic aid and high competition.
Audiovisual coeducation, gender, semiotics and cultural studies. Critical analysis of audiovisual culture and its coeducational dimension. Meaning and codification of gender in audiovisual discourses. Media interpellation: processes of identification and subjectivation.
Technical audits of ITS and ICT systems. Secretariat and management of European projects. Representation of the administration in standardisation and normalisation committees. Translation and evaluation of standards. Traffic and transport, ITS and ICT consultancy studies.
Research in the field of Augmented Reality, where real world information is increased with synthetic information. Augmented Reality systems require position locators, creation of synthetic information (usually 3D environments), and systems that integrate the real world with the synthetic one.
Neurodevelopmental disorders (NDD) are, by definition, dynamic and changing over time. This dynamism of neurodevelopmental disorders means that comorbidity with other disorders and diseases is very high throughout the life cycle, especially in adulthood and ageing. The aim of the Research Group is to study these disorders and their evolution over time, with special emphasis on techniques and methods that improve the abilities of the people who suffer from them and their family environment, so as to generate a better quality of life, promoting the general health not only of the person with a Developmental Disorder but of all the members of the family unit.
Development of automatic control algorithms for robotic systems and autonomous driving of vehicles in unstructured environments, using artificial intelligence techniques.
To advance methods of diagnosis and prevention of myocardial damage after acute myocardial infarction. The group will conduct an experimental analysis of the relationship between the characteristics of ischaemia-reperfusion injury and the inducibility and maintenance of ventricular arrhythmias.
Basic studies in psychophysics, mechanisms and models of visual processing. Physiological optics.
Development of multivariate dynamic models and their analysis by Bayesian mehtodology, using MCMC simulation methods. Incorporation of spatial dependencies into the temporal structure of the models. Design and implementation in R of algorithms for their analysis, estimation and prediction.
The main goal of this line is the development of bibliometric indicators useful in the evaluation of scientific activity that allow the easurement of research results and the performance of science, thus enabling public research policies to be better adapted.
Large database analysis in which there are three characteristics that make them special: growth velocity, variety in the data classes and volume.
Study of the kinetic and thermodynamic properties of membrane-active complexes. Description of the structure of active complexes and their formation mechanisms.
Methodology: Infrared, UV-Vis, DC and fluorescence spectroscopies. Fluorescence microscopy. AFM nanoscopy. Langmuir monocaps. Molecular simulations. Theoretical diffusion models. Statistical analysis.
Use of laser speckle techniques to study the activity of cell cultures and body deformations due to dynamic and light stress.
Study of the effects of biopower applied to the analysis of bodies, genders and sexualities. Social construction of health and illness.
Bone grafting studies in atrophic jaws and membrane placement.
The research group works on the modelling and multiscale simulation of the activation process of cardiac tissue, in order to characterise and predict different pathologies. The group has high-resolution simulation software that allows fully synthetic electrocardiograms to be reproduced, with the possibility of simulating different pathologies. Another active line of work in this field is the estimation of the cardiac conduction system using analysis of data acquired during surgical practice.
Study of the implications of caring for people with chronic conditions on the health of caregivers. Variables of vulnerability and protection. Application of intervention programmes for caregivers to prevent or improve their health.
Characterisation of electronic brachytherapy systems using Monte Carlo techniques. The response of commercially available ionisation chambers will then be calculated in order to obtain the correspondence factors that will allow their use in clinical practice.
We study the mechanisms responsible for the toxicity of antiretroviral therapy in different organs and tissues, with special emphasis on three of the main adverse effects associated with this treatment: liver toxicity, metabolic alterations and neurotoxicity.
Analysis of the role of practices, methods and techniques in the field of social intervention in the production of identities and sexualities.
The aim of this line is to investigate the pathophysiological mechanisms underlying chronic pain and to test the therapeutic efficacy of treatments targeting these mechanisms.
Design and testing of devices for visual function assessment, applied to the detection and characterisation of anomalies.
Nutritional assessment/intervention:
- Study of the functionality of bioactive compounds in patients with certain pathologies and/or treatments; retrospective and prospective population studies.
- Design and development of food products targeted to selected population groups.
This research line aims to improve the performance of Collaborative Augmented Reality (CAR) systems and applications, building on the group’s previous experience in Distributed Virtual Environments.
Molecular characterisation of colorectal cancer by liquid biopsy based on the analysis of ctDNA and CTCs. Application of radiomics in prognostic assessment. Study of the mechanisms of resistance to standard and targeted therapy and identification of new therapeutic targets. Development of clinical trials with drugs directed against potentially targetable alterations.
Properties of holomorphic functions and Banach spaces and algebras whose elements are these functions are studied.
Development of models with compositional data. In environments such as biology, economics or geology, it is common to work with data vectors whose components reflect the relative contribution of different parts in relation to a total, obtaining compositional samples. Work will be done on the progress of statistical modelling of compositional data, its application and its mathematical foundations.
Study of the neurobiological bases of cooperation and empathy, as well as the relationship between both and their social applications and inclusion in intervention programmes at different levels.
Research into learners' interlanguage, contrastive studies through corpus analysis, and the use of corpus techniques in language teaching and linguistics in the classroom (data driven learning).
Dental pathology: epidemiology, clinical manifestations, diagnosis and treatment. Quality of care and user satisfaction.
Design, synthesis and application of photoactive nanosystems.
Design of new polypeptide sequences with membrane activity from native proteins and peptides.
Methodologies: Computational analysis of polypeptide structures at various levels. Chemical synthesis of peptides.
The first step consists of migrating to C++ CUDA. Next, the numerical techniques needed to use it as an inverse scheduling algorithm will be improved. The final step would be to include it in a planning system and verify it in clinical practice.
WEB systems for access to databases. Semantic WEB, Ontologies and metadata. RDS dissemination systems and DATEX protocol data exchange systems. Development of WEB services. Mobile applications. Electronic forms, payment services and secure information processing.
Development of an animal model (New Zealand White rabbits) of metabolic syndrome and study of the impact of the combination of the different manifestations of the disease on cardiac electrical remodelling and its potential arrhythmogenic mechanisms.
Use and improvement of tools for genetic diagnosis of tumours.
Development, updating and integration of tools for the recording, processing and analysis of cardiac electrophysiological signals based on multi-electrode devices and optical mapping systems (voltage and calcium signal analysis).
Analysis of the effectiveness of tools designed by computational linguists and computer engineers in examining digital genres, such as computer-mediated communication. It includes the valuation or subjectivity conveyed by users in commercial and non-commercial uses.
Analysis of the fundamentals in the compilation of corpora, whether synchronic (current) or diachronic, monolingual or multilingual, for the examination of the language as a whole, or part of it. Analysis of the role of different types of annotation: grammatical, semantic, discursive, multimodal.
Diffractive lenses are very interesting elements because they are compact, lightweight and economical optical components. In this line of research, new designs are being developed for application in ophthalmology in the form of both intraocular (IOL) lenses and contact lenses.
Optical devices for manipulating pulses of tens of femtoseconds by using diffractive optical elements allowing spatial control of the wavefront of the pulsed beam, as well as the shaping of the temporal envelope of the ultra-short pulses.
Detection. Quantification and objective topology of biological parameters in histological samples.
Development of Bayesian hierarchical models for the study of the geographical variability of diseases and their temporal evolution with the aim of aiding decision-making and the development of surveillance programmes.
Ischaemia/reperfusion damage promotes pro-arrhythmogenic ventricular remodelling. The effects of histone deacetylase (DHA) enzyme inhibition on this process and its impact on electrophysiological properties and arrhythmogenesis will be discussed.
The current analytic chemistry and the adaptation of the new available instrumentation to research, allows the detection and characterisation of compounds at very low concentration levels, allowing the study of emerging pollulants, which only a few years ago was not possible to detect.
Endodontic materials. Irrigation techniques. Root canal preparation and obturation procedures. Material/dental tissue interface studies. Pathology of the dentin-pulp complex and its periapical complications.
The group studies the mechanisms of this enigmatic and common disease, its physiopathology and ways of early detection. It's also involved in the development of new medication for its treatment via clinical trials.
Study of the presence, transport, fate and bioavailability of emerging and priority pollutants in environmental compartments. Environmental risk assessment. Development of methods for environmental forensics and sewage epidemiology.
Analysis of the electrophysiological properties affecting the processes involved in the onset, perpetuation and cessation of VF, an arrhythmia responsible for about 80% of all sudden cardiac deaths, the underlying mechanisms of which remain incompletely understood.
Skeletal muscle regeneration involves the activation of satellite cells. The niche in which satellite cells live greatly increases FN expression when they are activated. We want to find out what role this FN plays
Study and improvement of ovarian tissue cryopreservation techniques, detection of occult metastatic diseases in breast cancer patients, in vitro activation and maturation, fertility preservation in leukaemia patients and uterus transplant.
The esTOCma app was developed to fight against the stigma associated with mental illness in general, and OC spectrum disorders in particular, by disseminating current knowledge and the possibilities for effective treatment and recovery from these disorders. https://estocma.blogs.uv.es/
The CoMMLab group uses computational fluid mechanics techniques applied to different fields. In biomedical engineering, the group uses fluid models for the simulation of the vascular system, especially in large vessels, to analyse and predict pathologies such as aneurysms. In the field of computer graphics, non Newtonian fluid models are developed with applications mainly in interactive simulation (Virtual Reality, Videogames, ...) and in simulations for physics-based animation and special effects.
Advanced chemical analysis. Characterisation of food quality and safety within the framework of food legislation. Foodomics: profiling and fingerprinting techniques for food characterisation, authenticity and origin characterisation.
Microbiological control of food- Traceability systems and HACCP- Analyses of pollutants through liquid chromatography-mass spectrometry: Study of extraction techniques, Development of analytical methods, Interpretation of analytical data by means of chemometric techniques.
Hardware implementation of biosignal processing algorithms in FPGA (Field Programmable Gate Array) reconfigurable devices. Development of software tools for the fast migration (Rapid Prototyping) of certain computer-based algorithms to their hardware implementation in stand-alone electronic devices (embedded systems).
The research line focuses on research in health services and technologies applied to health, and on the design, implementation and evaluation of health promotion and disease prevention interventions.
Developments in high-performance computing, using advanced computer architectures, for the processing and analysis of methylation in genomic data produced by Next-Generation Sequencing (NGS).
Design of printed circuit boards for high-speed digital electronics.
Advanced analysis. Human diet studies. Integrated risk assessment.
To examine transcultural variants of IMD (for its Spanish acronym, Unpleasant Mental Intrusions) with obsessive, dysmorphic, hypochondriacal and alimentary content.
Security analysis of computer systems, vulnerability detection, cryptography and secure communications. Mechanisms for the protection of personal data, traceability of information, privacy and security-oriented design. Data anonymization. Security audits. International regulations.
Studies on buttress implants and rehabilitation of patients with large maxillary atrophies. Studies of zygomatic, palatalised, frontomaxillary and pterygoid implants.
This research line seeks to understand how ovaries in female patients undergoing in vitro fertilisation work and to improve the results by reducing complications.
Electronic devices design and programming for the process automation in the industry. Equipment based on Programmable Logic Controllers supported by Human Machine Interface (HMI) systems, SCADA, industrial vision equipment, robotics, etc. Development of automated manufacturing and production systems using the technologies necessary for optimum factory operation. Applications in water treatment (drinking and waste water), automobile manufacturing and their components, food, and chemical processes (pharmacology, petrochemistry, cosmetics).
Basis of the inflammatory process. Anti-inflammatory drugs. New approaches to the treatment of inflammatory diseases. Arthritis. Osteoarthritis. Osteoporosis
Using intravital microscopy experiments in mouse cremaster muscle venules after injury, we are studying the speed of clot formation and clot stability in FN-Syn mice.
Assessment of scientific activity and analysis of the sharing of raw research data in the health sciences.
Design of tools based on ICT in the teaching, welfare and healthcare fields.
Infrared thermography is a completely non-injurious technique that allows the evaluation of surface temperature changes due to superficial vascular variations and in general alteration of thermoregulation, and is therefore applicable to the medical and sports fields.
We are currently working on forms of knowledge representation that allow the supervision of the students tasks resolution, as well as the incorporation of affective support through the detection of emotions by means of typical techniques within the field of computer vision
Application of automatic learning techniques for problems with prediction, classification and recognition of patterns or trends.
The main objective is to learn the basic principles for carrying out tasks of various kinds (driving vehicles, handling objects, surface treatment, etc.), to predict human intentions in situations where there is shared control and to provide personalised assistance.
Development of portfolio selection models, in which uncertainty about performance is described by possibility and credibility distributions. Multi-objective analysis of the selection problem, seeking approximations to the Pareto front using evolutionary algorithms.
Development of multi-agent simulation systems applied to social and healthcare systems, so that they can simulate not only the individual behaviour of each agent, but also the global behaviour of the system as an addition of individual behaviour.
The possibility of wavefront recording has as a potential application the realisation of microscopy techniques in which no objectives are used for imaging. Various techniques are developed, using a variety of light sources for the inspection of samples.
Evaluation of corpus linguistics in the compilation and elaboration of monolingual, multilingual lexicography, including phraseological aspects, the writing of grammars based on actual language use and translation.
Properties of bounded operators between Banach spaces are studied, as well as multilinear applications and polynomials in Banach spaces and the spaces formed by these applications.
Field of programmable optical components (diffractive elements, filters and polarisation components), and their realisation by means of spatial light modulators (basically liquid crystal displays).
Electronic toll collection systems and mobile vehicles. Satellite and telephony location systems. GPS and GSM applications. V2V, V2I and I2V communication systems. Bluetooth, RFID and WIFI detection systems. Cooperative systems. Dynamic navigation.
Longitudinal and survival data joint models with time or survival targets are studied, with special emphasis on dynamic predictive targets.
Design of low-noise analogue circuits.
In addition to the experience acquired over the years by the members of the group in different areas of simulation, mainly in bioengineering and mechanical engineering, recent advances in machine learning have been assimilated by the group as another way of exploiting the results of its simulations. The group has applied these techniques to the development of pedestrain models applied to crowd simulation. It also allows a further step in transferring the results of the simulations to new medical and industrial sectors (i.e. predictors of ectopic foci, aneurysms, arrhythmia detectors, etc.).
Direct and indirect sinus floor elevation studies. Bone graft studies in maxillary sinus floor elevation.
Our goal is to explore the mechanistic principles of membrane protein insertion, folding and assembly into lipid membranes and to investigate the factors that determine membrane protein stability.
Overexpression of membrane proteins is often essential for structural and functional studies, but yields are frequently too low. Therefore, we investigate the consequences of overexpression of different membrane proteins in search for new components to improve such yields.
Aimed at developing the validation strategies for the analytical parameters of a procedure.
New analysis strategies in miniaturised chromatographic techniques which incorporate solid phase microextraction in tubes with new (nano)materials.
We studied type 2 diabetes and mitochondrial dysfunction, having shown that it correlates with the development of silent ischaemic heart disease. We have also shown that high levels of myeloperoxidase correlate with the development of diabetic nephropathy in type 2 diabetes.
Our group addresses the problem of model selection from a Bayesian target point of view. We particularly work on the study of criteria that allow us to establish optimal prior distributions in order to carry out an effective selection and modeling.
Modelling and design of waveguides and other photonic devices, such as photonic-crystal fibers, integrated semiconductor and dielectric guides and resonators, fibre optic lasers, or metamaterials.
We study the mechanisms that regulate gastrointestinal mucosal recovery in chronic inflammatory pathologies (e.g. IBD), in particular how macrophages, cells of the innate immune system that accumulate in the mucosa of patients with this pathology, modulate these mechanisms.
Traffic monitoring, vehicle magnetic fingerprint identification systems, DAI systems, applications for route and/or time optimisation, travel times, O/D matrices, GIS applications, geographic data representation and virtual simulation. Emergency management plans.
Development of human-computer interaction technologies making use of different communication channels between user and computer.
The research is planned in two directions: nanomaterials characterisation including strategies for its detection and/or analytic determination and the study of its characteristics and its influence in the improvement of analytic parameters.
Extraction of structured information and knowledge from the analysis of free texts and a priori unstructured information.
This line of research focuses on the development of new network architectures and protocols, as well as on the creation of advanced telecommunication systems to improve communications between users. This work includes the development and implementation of our new services, technologies and network architectures centred on enhancing the quality of the final user’s experience.
Study of the biological bases of violent and criminal behaviour, with its applications at diagnosis, prevention and intervention levels in violence.
Study of the biological bases of happiness. Application of neurosciences to Positive Psychology. Intervention, prevention and other applications.
Study of the processes of precariousness in social contexts discursively dominated by the knowledge economy and which particularly involve people with higher education qualifications. Phenomena: entrepreneurial activation, new forms of vital precariousness and the role of higher education institutions.
Design and adaptation of new food products from traditional foodstuffs, Food enrichment/fortification, Evaluation of the nutritional composition of food products and its improvement, Study of new materials, Study of stability.
Functional genomics of lung cancer. Identification of new markers and molecular targets for the treatment of lung cancer using omics technologies (transcriptomics, proteomics, metabolomics). Study of the mechanisms of innate and acquired resistance to tyrosine kinase inhibitors based on the epithelial-mesenchymal transition (EMT) and the cancer stem cell (CSC) phenotype. Regulation of tumour metabolism by oncogenes and suppressor genes in lung cancer.
Identification of new markers and molecular targets for the treatment of pulmonary fibrosis. Identification of molecular determinants of fibroblast-myofibroblast transition using omics technologies. Role of inflammation and stroma in the tumour microenvironment and lung cancer progression.
Identification of new markers associated with oxidative metabolism by mass spectrometry. Study of pathologies associated with oxidative stress and tissue hypoxia. Cellular and molecular mechanisms of the prevention of tissue damage in hypoxic-ischaemic neuropathies by means of natural and synthetic polyphenols.
Design and validate new models of CBT dispensing for OC spectrum disorders, specifically Virtual Reality and mobile applications (App) to facilitate CBT dispensing and dissemination.
Design and proposal of systems to improve measurements, images and techniques in optometric and ophthalmological practice.
Persigue desarrollar conocimiento científico que genere nuevas herramientas que se adapten a las necesidades actuales de la sociedad. Los beneficios que pueden aportar son: bajo coste, no consumen energía, versatilidad del emplazamiento, uso puntual, evaluación de grandes áreas con resolución específica.
Comparative validity of the several proposals on the disorders to be included in the obsessive-compulsive spectrum.
Analyse whether the different symptomatic manifestations of OCD are:
- Consequence of diffeent aetiopathogenic factors.
- Respond differently to empirically validated psychological treatments (i.e., Cognitive Behavioural Therapy, CBT).
- They present a different comorbidity.
To analyse the different cognitive explanatory proposals for OCD (model based on dysfunctional appraisals versus inferential confusion) in relation to the context of occurence of intrusions/obsessions, the self, cognitive variables and content of thoughts.
Biomechanics of intraradicular pins. Materials and techniques for dental restoration. Tooth reconstruction with root canal treatment.
Techniques for improving resolution in optical systems. Under certain conditions, the limits imposed by diffraction or sensors can be overcome. These techniques are used in microscopy and in all imaging applications.
The line focuses on the application of high performance computing techniques, and the development and optimisation of distributed platforms within the cloud computing paradigm, for Big Data, multimedia applications and intelligent systems problem solving.
Recognition and machine learning techniques applied to linear and nonlinear models. Continuous Distance Learning. Heterogeneous and multi-dimensional data mining, with special emphasis on image analysis and recovery and the processing of audio and video signals.
Analysis of the production of pedagogical identity in specific contexts of educational and professional transition from a Social Justice perspective. Construction of the social positioning of young people in institutional transition processes. Analysis of Educational Policies from a critical perspective: conservative modernisation.
Maintenance studies on implants and peri-implantitis.
Pharmacokinetic evaluation of drugs administered intravenously, orally and through the skin, especially those with bioavailability problems and/or plasma concentrations with high variability and which correlate poorly with the dose administered.
This field exploits the ability to perform wavefront capture by holographic methods to obtain phase measurements of objects, mainly in microscopy. The techniques are analogous to those required for 3-D capture in metrology.
In this line of research, studies are carried out to quantify the habitual physical activity of groups of people with some special situation, usually a pathology that affects the musculoskeletal system. In this way, the aim is to establish the effect of the practice of physical activity on parameters related to the health and functionality of these people.
To assess the effect of therapeutic exercise and physiotherapy on cardiocirculatory function in adults and older adults with cardiovascular disease, as well as to study the effectiveness of strategies to improve adherence to a physically active lifestyle in these subjects.
Physiotherapy from a global perspective can improve the health of patients with respiratory problems. This line of research aims to develop new tools and implement interventions to assess the prognosis and improve the functional capacity of these patients.
This line focuses on the search for assessment tools and the definition of health promotion and specialised physiotherapy intervention programmes for young children with psychomotor developmental disorders as well as for children or adults with neurological pathologies.
Pedagogical relations in contexts of social and educational exclusion (poverty, ghettoisation, ethnic minorities). Analysis of policies to combat failure and early school leaving. Curricular justice and educational equity. Childhood and RECE.
Galenic development, preferably modified-release oral and topical dosage forms. Evaluation of transdermal administration with iontophoresis. The studies help to guide the selection of the adjuvant substances used in the formulation of…
Development of reinforcement learning models and dynamic programming for cost reduction, the improvement of important parameters and the increase of efficiency.
Study of pedagogical practice based on Basil Bernstein's theory. Analysis of the processes of distribution and construction of legitimate knowledge in the pedagogical device. Pedagogical modes of transmission. Sociology of pedagogy. Critical pedagogy and critical table.
To analyse attitudes, professional values and other parameters related to professional ethics and health in physiotherapists, physiotherapy students and patients. To design and validate assessment tools. To study the effectiveness of innovative programmes on ethics and health in physiotherapy.
Skin inflammation, psoriasis, wound healing.
Active and healthy ageing is a construct of growing relevance. In its psychological aspect, clinical (cognitive and emotional), functional, cultural and socio-familial aspects must be included, as well as different demographic and lifestyle variables. Among the objectives of the group is the assessment and intervention throughout the life cycle, including the optimisation of their development, both of the persons or patients involved and their family environment, carers, etc., especially in the cognitive, emotional, functional and lifestyle areas. Within frailty in ageing, the topic of cognitive frailty and the variables involved in it is of particular interest.
Use of formalism of quantum mechanics to improve the performance of machine learning algorithms. Use of machine learning for the description and extraction of quantum phenomena knowledge.
FN-RGE mice express FN that cannot bind a5ß1 integrins, but does bind av class integrins. We are studying how knee cartilage evolves in these mice after injury induction.
Development of product recommendation engines based on the characteristics of the customer and management of personalised promotions.
Using the self-interference produced when coherent light strikes a diffusing surface, techniques are employed that allow the detection of nanometre-amplitude motion of the objects under analysis. This allows vibrations and sound to be measured over large distances.
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Analysis of the effects of alterations in calcium homeostasis on arrhythmogenesis. Search for and study of the electrophysiological effects of drugs that act on intracellular calcium dynamics.
Development of equipment and algorithms custom-made for their aqcuisition and signal processing.
Theoretical studies for the improvement of signal integrity (reduction of coupling and electromagnetic emission in high-speed digital transmission systems. Study of power distribution schemes to improve the quality of digital signals.
Advanced methods for the capture, analysis and synthesis of acoustic signals, including musical and voice processes, acoustic simulation of rooms, 3D reproduction methods and intelligent monitoring of acoustic environments.
Simulation models for animation of complex behaviours in interactive graphics applications, including physical behaviours (fluids, granular systems, etc.) and behaviours based on artificial intelligence (reinforcement learning, etc.).
Study by computational tools of chemical reactions in enzymes and aqueous solution by means of QM/MM Molecular Dynamica.
Our hypothesis suggests that the adhesions made by the keratinocyte with FN, which are necessarily mediated by a5ß1 integrins, are weaker. To study this, we are using microprinting of FN-syn lines of different thicknesses and distances that force the cell to withstand more stress.
To contribute to the body of knowledge on human behaviour and social interaction by collecting data of interest from different social sectors and decision-makers in the public and private spheres, as well as from research personnel.
Development of statistical methodologies for the rapid and reliable detection of influenza epidemics. We approach the inference and prediction of these models from the Bayesian paradigm, which allows the implementation of complex models with spatial, temporal and hierarchical structures.
Deepen knowledge of common musculoskeletal injuries in patients with haemophilia and their sequelae, as well as design and validate assessment methods. Study the effectiveness of physiotherapy techniques and protocols to improve physical function and quality of life.
Development of models to predict the spatial and spatial-temporal distribution of species. The incorporation of uncertainty in covariates, the problems generated by missing values, the effect of preferential sampling and the handling of large volumes of data are addressed.
Biomechanical evaluation and analysis of any type of physical activity, especially during running, walking and cycling, as well as the analysis of sports activity from the applied perspective of sports biomechanics and physiological variables.
Evaluation and analysis of sports equipment and apparel materials, especially plantar supports, footwear, compressive fabrics, and other sports textile apparel materials.
Assessment of factors that may help promote cognitive reserve and healthier ageing as well as mechanisms that may protect against the deleterious effects of stress.
Functionality and bioavailability tests in cell cultures and in-vitro. Metabolomic analysis (LC-MS) and interpretation of results (Foodomics), Characterisation of bioactive compounds, Evaluation of stability in matrices, Bioavailability in vitro of bioactive compounds.
Once the development of effective algorithms has been completed, the necessary computed tomography-ultrasound fusion-strain techniques will be implemented. They will then be implemented in a commercial planning system and clinically verified.
Study of the population affected by or at risk of osteoporosis and its improvement and prevention through physical exercise using a working system with elastic bands that is easy to handle and applicable to home treatment.
Study of tendon pathologies in general and tendon injuries in sports in particular, and their recovery using a work methodology with physical activity.
We study the mechanisms responsible for the vascular toxicity described for some antiretroviral drugs. We have analysed the effect of the most commonly used antiretroviral drugs on leukocyte-endothelium interaction as a first step in the development of vascular pathologies.
The following beams will be studied: 6 MV, 12 MV, Esteya, HDR & LDR brachytherapy source; the chambers of PTW: Soft X-Ray Chamber Type 23342, 23344 and 34013, Farmer Chamber Type 30010, 30011, 30012 and 30013, Semiflex Chamber Type 31010, 31013 and 31021, Roos Chamber Type 34001 and Advanced Markus Chamber Type 34045.
Development and characterisation of devices, based on the processing carried out by the visual system: colourimetric characterisation of image capture and display devices, image processing. Characterisation of optical devices.
This is a pioneering work with international collaboration and the first in the world to study the influence of the genetic factor on tendinopathies in the shoulder in different populations where we will study sportsmen, haemophiliacs, disabled people in wheelchairs and the general population.
The study of pseudo-differential operators with time-frequency analysis methods.
Diagnosis and treatment of dental colour pathology. Colorimetry. In vivo and in vitro studies on bleaching agents and procedures.
To find out which variables of factors operate transdiagnostically in the various dimensions and/or subtypes of OCD and in other disorcers of the emotional spectrum (anxiety and mood disorders). Specifically, we focus the study on unpleasant mental intrusions (IMD for its Spanish acronym).
We want to cross a strain of tumour-prone mice with our FN-syn mice and analyse the influence of this mutation on tumour development, migration and metastasis formation of tumour cells.
Research in the interaction paradigm based on immersive virtual environments where the user is isolated from the environment and introduced in a synthetic environment in order to perform a training or live a different experience. Includes use of specific devices.
