In this conference we will present the main future challenges we have to confront towards the development of an economically, socially and environmentally sustainable system. Furthermore, we will discuss the contributions of the Chairs of Economics for the Common Good, Feminist Economics and Business and Humanism, which have been creating and disseminating useful knowledge to respond to these challenges since 2016, thanks to the support of the Regional Ministry of Sustainable Economy, Productive Sectors, Trade and Labour of the Valencian government.