Description
Many compounds of pharmaceutical interest have an acid-base character, therefore the nature and concentration of the dominant species depend on pH. Models of mobile phase behaviour are developed in the absence and presence of additives, and with conventional or extended pH columns.
Keywords
HPLC, acid-base species, drugs, retention models, optimisation, pharmaceutical analysis
Manager UV
- Torres Lapasio, Jose Ramon
- PDI-Titular d'Universitat
Frascati classification
