The main objective of this line is to better understand, from a molecular point of view, non-alcoholic fatty liver disease. This disease has pandemic overtones as it affects a high percentage of our population. The difficulty lies in the fact that it is a multifactorial disease, with diverse and incompletely understood aetiological mechanisms. The group is mainly investigating transcriptional causal mechanisms. We are also interested in the specific pathways leading to metabolic steatosis and steatosis caused by xenobiotics, such as drugs. From basic knowledge we hope to find predictive and diagnostic biomarkers that allow better management of this disease.
Non-alcoholic fatty liver disease, metabolic steatosis, iatrogenic steatosis, transcriptional mechanisms, predictive biomarkers
