2012

Publicaciones 2012
Gelis S; de Groot PWJ; Castillo L; Moragues MD; Sentandreu R; Gómez MM; Valentín E. PgA 13 in Candida albicans is localized in the cell wall and influences cell surface properties, morphogenesis and virulence. Fungal Genetics and Biology.49, 322–331 (2012).
Collado R, Oliver I, Tormos C, Egea M, Miguel A, Cerdá C, Ivars D, Borrego S, Carbonell F, Sáez GT. Early ROS-mediated DNA damage and oxidative stress biomarkers in Monoclonal B Lymphocytosi. Cancer Lett. 28;317(2):144-149. (2012)
Mitjavila, M.T., Fandos, M., Salas-Salvadó, J., Covas, M.I., Borrego, S., Estruch, R., Lamuela-Raventós, R., Corella, D., Martínez-Gonzalez, M.A., Sánchez, M.J., Bulló, M., Fitó, M., Tormos, C., Cerdá, C., Casillas, R., Moreno J.J., Iradi, A., Zaragoza, C., Chaves, J., Sáez, G.T. The mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled, trial. Clin. Nutr. (2012)
Ortega-Azorín C, Sorlí JV, Asensio EM, Coltell O, Martínez-González MA, Salas-Salvadó J, Covas MI, Arós F, Lapetra J, Serra-Majem L, Gómez-Gracia E, Fiol M, Sáez-Tormo G, Pintó X, Muñoz MA, Ros E, Ordovás JM, Estruch R, Corella D.Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low. Cardiovasc Diabetol. Nov 6; 11(1):137(2012)
Pedro T, Martinez-Hervas S, Tormo C, García-García AB, Saez-Tormo G, Ascaso JF, Chaves FJ, Carmena R, Real JT.Oxidative stress and antioxidant enzyme values in lymphomonocytes after an oral unsaturated fat load test in familial hypercholesterolemic subjects.Transl Res. Oct 13. doi:pii: S1931-5244(12)00303-9. 10.1016/j.trsl.2012.09.002. (2012)
Tresserra-Rimbau, A., Medina-Remón, A., Pérez-Jiménez, J., Martínez-González, MA., Covas, M.I., Corella, D., Salas-Salvado, J., Gómez-Gracia, E , Lapetra, J., Arós, F., Fiol, M., Ros, E., Serra-Majem L., Pintó, X., Munóz, M.A, Saez, G.T, Ruiz-Gutiérrez, V., Warnberg, V., Estruch R., Lamuela-Raventós, R.M. Dietary intake and major food sources of polyphenols in a Spanish population at high cardiovascular risk: The PREDIMED study (2012)
Saéz G.T. DNA damage and repair in degenerative diseases. Int. J. Mol. Sci. Special Issue. Invited Guest Editor. (2012).
Moya M, Benet M, Guzman C, Tolosa L, Garcia-Monzon C, Pareja E, Castell JV and Jover R. Foxa1Reduces Lipid Accumulation in Human Hepatocytes and Is Down-regulated in Nonalcoholic Fatty Liver. PLoS-ONE. 7(1):e30014. (2012).
Guzman C, Benet M, Moya, Pisonero S, García-Mediavilla MV, Martínez-Chantar ML, González-Gallego J, Castell JV, Sánchez-Campos S and Jover R. The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARa; and repressed by C/EBPa: implications in FABP1 down-regulation in nonalcoholic fatty liver disease. BBA Molecular and Cell Biology of Lipids. (2012)
Gómez-Lechón MJ, Lahoz A, Castell JV, Donato MT Evaluation of cytochrome P450 activities in human hepatocytes in vitro . Methods Molecular Biology 806:87-97 (2012)
Donato MT, Tolosa L, Jiménez N, Castell JV, Gómez-Lechón MJ. High-Content Imaging Technology for the Evaluation of Drug-Induced Steatosis Using a Multiparametric Cell-Based Assay. Journal of Biomolecular Screening 17(3):394-400 (2012)
Tolosa L, Donato MT, Pérez-Cataldo G, Castell JV, Gómez-Lechón MJ. Upgrading cytochrome P450 activity in HepG2 cells co-transfected with adenoviral vectors for drug hepatotoxicity assessment. Toxicology In Vitro 26 (8):1272-7 (2012)
García-Cañaveras JC, Donato MT, Castell JV, Lahoz A. Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method. Journal of Lipid Research 53 (10):2231-41 (2012)
Donato MT, Gomez-Lechon MJ. Drug-induced Liver Steatosis and Phospholipidosis: Cell-Based Assays for Early Screening of Drug Candidates. Current Drug Metabolism 13 (8):1160-73 (2012)
Tolosa L, Pinto S, Donato MT, Lahoz A, Castell JV, O'Connor JE, Gómez-Lechón MJ. Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. Toxicological Sciences 127(1):187-98 (2012)
Freville, A., Landrieu, I., Garcia-Gimeno, M.A., Vicogne, J., Montbarbon, M., Bertin, B., Verger, A., Kalamou, H., Sanz, P., Werkmeister, E., Pierrot, C. and Khalife, J. “Plamodium falciparum inhibitor 3 homolog increases protein phosphatase type1 activity and is Essentials for parasitic survival. J.Biol.Chem, 287, 1306-1321 (2012).
Criado, O., Aguado, C., Gayarre, J., Duran-Trio, L., Garcia-Cabrero, A.M., Vernia, S., San Millan, B., Heredia, M., Romá-Mateo, C., Mouron, S., Dominguez, M., Navarro, C., Serratosa, J.M., Sanchez, M., Sanz, P., Bovolenta, P., Knecht, E. and Rodriguez de Cordoba, S. Lafora bodies and neurological defects in malin-deficient mice correlates with impaired autophagy. Hum. Mol. Genet. 21,1521-1533, (2012).
Knecht, E., Criado, O., Aguado, C., Gayarre, J., Duran, L., Garcia-Cabrero, A.M., Vernia, S., San Millán, B., Heredia, M., Romá-Mateo, C., Mouron, S., Juana-López, L., Domínguez, M., Navarro, C., Serratosa, J.M., Sanchez, M., Sanz, P., Bovolenta, P. and Rodriguez de Cordoba, S. Malin knockout mice support a primary role of autophagy in the pathogenesis of Lafora disease. Autophagy, 8, 701-703, (2012).
Gentry, M.S., Romá-Mateo, C., Sanz, P. Laforin, a protein with many faces: glucan phosphatase, adaptor protein, et alii FEBS Journal doi: 10.1111/j.1742-4658.2012.08549.x. (2012)
Garcia-Gimenez, J.L., Velazquez-Ledesma, A.M., Esmoris, I., Romá-Mateo, C., Sanz, P., Viña, J., Pallardo, F.V. Histone carbonylation occurs in proliferating cells. Free Rad. Biol. Med. 52, 1453-1464 (2012).
Roma-Mateo, C., Sanz, P., Gentry, M.S. Deciphering the role of malin in the Lafora progressive myoclonus epilepsy. IUBMB Life, 64, 801-808 (2012).
Garcia-Haro,L., Garcia-Gimeno, M.A., Neumann, D., Beullens, M., Bollen, M., and Sanz, P. “Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway”. FEBS Letters 586, 4241-4247 (2012).
Gil-Benso R, Monteagudo C, Cerdá-Nicolás M, Callaghan RC, Pinto S, Martínez-Romero A, Pellín-Carcelén A, San-Miguel T, Cigudosa JC, López-Ginés C. Characterization of a new human melanoma cell line with CD133 expression. Hum Cell. Jun; 25(2):61-7. (2012)
Megías, J., Yáñez, A., Moriano, S., O'Connor, J.-E., Gozalbo, D., Gil, M.L. Direct toll-like receptor-mediated stimulation of hematopoietic stem and progenitor cells occurs in vivo and promotes differentiation toward macrophages Stem Cells, 30 (7), pp. 1486-1495. (2012)
Gibellini, L., de Biasi, S., Pinti, M., Nasi, M., Riccio, M., Carnevale, G., Cavallini, G.M., Oyanguren, F.J.S., O'Connor, J.E., Mussini, C., de Pol, A., Cossarizza, A. The protease inhibitor atazanavir triggers autophagy and mitophagy in human preadipocytes. AIDS(2012)
Clothier R, Gómez-Lechón MJ, Kinsner-Ovaskainen A, Kopp-Schneider A, O'Connor JE, Prieto P, Stanzel S. Comparative analysis of eight cytotoxicity assays evaluated within the ACuteTox Project. Toxicol In Vitro. Aug 23. doi:pii: S0887-2333(12)00222-6. 10.1016/j.tiv.2012.08.015. (2012)
Prieto P, Kinsner-Ovaskainen A, Stanzel S, Albella B, Artursson P, Campillo N, Cecchelli R, Cerrato L, Díaz L, Di Consiglio E, Guerra A, Gombau L, Herrera G, Honegger P, Landry C, O'Connor JE, Páez JA, Quintas G, Svensson R, Turco L, Zurich MG, Zurbano MJ, Kopp-Schneider A. The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: Results from the European Project ACuteTox. Toxicol In Vitro. 2012 Aug 16. doi:pii: S0887-333 (12) 00217-2. 10.1016/j.tiv.2012.07.013.
Codoñer-Franch, P; Tavárez-Alonso, S; Murria-Estal, R; Tortajada-Girbés, M; Simó-Jordá, R; Alonso-Iglesias, E. Elevated advanced oxidation protein products (AOPPs) indicate metabolic risk in severely obese children. Nutrition Metabolism and Cardiovascular Diseases, 22: 237-243. (2012).
Codoñer-Franch, P; Tavárez-Alonso, S; Simó-Jordá, R; Laporta-Martín, P; Carratalá-Calvo,A; Alonso-Iglesias, E. Vitamin D status is linked to biomarkers of oxidative stress, inflammation, and endotelial activation in obese children. Journal of Pediatrics, 161: 848–854. (2012)
Tavárez-Alonso, S; Codoñer-Franch, P; O´Connor-Blasco, JE; Alonso-Iglesias, E. Looking at polyamine metabolism and functions: results from different experimental models of cardiovascular risk support their relation to body oxidant status. FEBS Journal, 279: 286-287. (2012)
Dasí F.; Navarro-García M.M.; Jiménez-Heredia M.; Magraner J.; Viña J.R.; Pallardó F.V.; Cervantes A.; Morcillo E. Evaluation of the Quality of Publications on Randomized Clinical Trials Using the Consolidated Standards of Reporting Trials (CONSORT) Statement Guidelines in a Spanish Tertiary Hospital.Journal of Clinical Pharmacology.52: 1106 –1114 (2012)
Bodi V.; Sanchis J.; Morales J.M.; Marrachelli V.G.; Nuñez J.; Forteza M.J.; Chaustre F.; Gomez C.; Mainar L.; Miñana G.; Rumiz E.; Husser o.; Noguera I.; Diaz A.; Moratal D.; Carratala A.; Bosch X.; Chorro F.J.; Viña J.R.; Monleon D. Metabolomic profile of human myocardial ischemia by nuclear magnetic resonance spectroscopy of peripheral blood serum: a translational study based on transient coronary occlusion models. Journal of the American College of Cardiology. 59:1629 – 1641 (2012)
Rodeiro I, Gomez-Lechon MJ, Tolosa, Perez G, Hernandez I, Menendez R Regalado EL, Castell JV, Donato MT. Modulation of biotransformation and elimination systems by BM-21, an aqueous ethanolic extract from Thalassia testudinum, and thalassiolin B on human hepatocytes. Journal of Functional Foods. 2012. 4: 167-176.

Publicaciones año 2012